الصفحة 52
الصفحة 52
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Apoptotic pathways as targets for novel therapies in cancer and other diseases

The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients.

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Anxiety in health behaviors and physical illness

While the links between physical illness and depression have been well-documented and analyzed, little has been made of the data relating physical illness to anxiety—until now. Anxiety in Health Behavior and Physical Illness explores complex relationships between medical and anxiety pathology on the theoretical, research, and practical fronts. Over forty experts examine reciprocal roles of anxiety and medical illness as causal or exacerbating factors in each other’s onset and development, describe forms of anxiety typical to major disease entities, discuss common health behaviors as they impact anxiety, recast anxiety disorders as chronic illness, and identify patients for whom new forms of treatment may be warranted.

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Antifouling Compounds

Increasing awareness of the deleterious effects of toxic components in antifouling coatings has raised interest in the potential for nontoxic alternatives. This book examines how marine organisms from bacteria to invertebrates and plants use chemicals to communicate and defend themselves. Chemicals that prevent colonisation of living surfaces are particularly pertinent to antifouling technology and may inspire new solutions. The challenge is to identify such compounds, identify the means for sustainable production and incorporate them into coatings to give long-term antifouling efficacy.

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Anesthesia Considerations for the Oral and Maxillofacial Surgeon

Strengthens the margin of safety of office-based anesthesia administration by helping practitioners determine whether the patients they treat are good candidates for office-based anesthesia. This book is organized into three sections. The first section provides a review of the principles of anesthesia, including the pharmacology of anesthetic agents, local anesthesia, patient monitoring, preoperative evaluation, the airway, and management of emergencies and complications. The major organ systems of the body are reviewed in section two, and the most common comorbid conditions that affect these systems are described in terms of their pathophysiology, diagnosis, management, and anesthesia-related considerations. Section three reviews patient groups that warrant special consideration in the administration of office-based anesthesia, such as geriatric, pediatric, pregnant, and obese patients. Spiral-bound and featuring tabs for quick and easy reference, this important book belongs on the shelf of every clinician who provides anesthesia in the office setting.

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Ancient monuments and modern identities : A critical history of archaeology in 19th and 20th century Greece

Sets out to examine the role of archaeology in the creation of ethnic, national and social identities in 19th and 20th century Greece. The essays included in this volume examine the development of interpretative and methodological principles guiding the recovery, protection and interpretation of material remains and their presentation to the public. The role of archaeology is examined alongside prevailing perceptions of the past, and is thereby situated in its political and ideological context. The book is organized chronologically and follows the changing attitudes to the past during the formation, expansion and consolidation of the Modern Greek State. The aim of this volume is to examine the premises of the archaeological discipline, and to apply reflection and critique to contemporary archaeological theory and practice.

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Analyzing the availability of fin tech and its role in enhancing the strategic : Performance of Syrian banks using the balanced scorecard

Aims to examine the role of financial technology (FinTech) in enhancing the strategic performance of Syrian banks by analyzing its impact on the four dimensions of the balanced scorecard : financial performance, customer satisfaction, internal process quality, and learning and growth. Amid economic and technological challenges, integrating fintech emerges as a strategic tool to boost operational efficiency, reduce costs, and promote financial inclusion. The study explores the experiences of several Syrian banks in implementing modern financial technologies, such as digital banking and smart payment systems, while evaluating key financial indicators like return on assets (ROA) and return on equity (ROE).

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Analyzing computer system performance with Perl::PDQ

Analyzing computer system performance is often regarded by most system administrators, IT professionals and software engineers as a black art that is too time consuming to learn and apply. Finally, this book by acclaimed performance analyst Dr. Neil Gunther makes this subject understandable and applicable through programmatic examples. The means to this end is the open-source performance analyzer Pretty Damn Quick (PDQ) written in Perl As the epigraph in this book points out, Common sense is the pitfall of performance analysis. The performance analysis framework that replaces common sense is revealed in the first few chapters of Part I. The important queueing concepts embedded in PDQ are explained in a very simple style that does not require any knowledge of formal probability theory. Part II begins with a full specification of how to set up and use PDQ replete with examples written in Perl. Subsequent chapters present applications of PDQ to the performance analysis of multicomputer architectures, benchmark results, client/server scalability, and Web-based applications.

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Analytical scientists in pharmaceutical product development : Task management and practical knowledge

Explains task management concepts and outlines practical knowledge to help pharmaceutical analytical scientists become productive and enhance their career. •Presents broad topics such as product development process, regulatory requirement, task and project management, innovation mindset, molecular recognition, separation science, degradation chemistry, and statistics. •Provokes thinking through figures, tables, and case studies to help understand how the various functions integrate and how analytical development can work efficiently and effectively by applying science and creativity in their work. •Discusses how to efficiently develop a fit-for-purpose HPLC method without screening dozens of columns, gradients, or mobile phase combinations each time, since the extra effort may not provide enough of a benefit to justify the cost and time in a fast-paced product development environment.

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Analysis of failure in fiber polymer laminates : the theory of Alfred Puck

This book presents for the first time comprehensively the Theory of Alfred Puck on failure in Fiber Polymer Laminates. After a brief introduction into the failure analysis of laminates and its history, the text focuses first on Puck’s fracture criteria and gives detailed information on their physical background, mathematical derivation and application. Another core part of Puck’s Theory is his concept for Post Failure Analysis. Here, too, the physical background and the analytical procedure are presented. The theoretical chapters are completed by the presentation of the latest developments, namely the consideration of residual stresses and probabilistic effects. The second main part of the book deals with the extensive experimental verification program which has been accomplished since the mid 1990’s. As a result of this work, the Puck Theory can be regarded as better verified than any other theory. All experimental set ups and the major results are presented and explained.

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Analysis and Design of Information Systems : Third ed.

This third edition of the successful Analysis and Design of Information Systems provides a comprehensive introduction and user-friendly survey to all aspects of business transformation and analysis, and aims to provide the complex set of tools covering all types of systems, including legacy, transactional, database, and web/e-commerce topics.

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Analysis and Control of Ultrafast Photoinduced Reactions

 The present monograph summarizes, in a comprehensive way, several years of joint experimental and theoretical frontier research on ultrafast laser-induced molecular dynamics and its control. Emphasis is set on the characterization of the nuclear dynamics within molecular systems in various environments (gas phase, surfaces, solids, solution, strong fields) triggered by optical excitations spanning from the infrared to the ultraviolet. Building on the converged analysis between experiment and theory, control of chemical reactions is established by means of optimally shaped laser pulses. This paves the road toward new applications and future challenges in this rapidly developing research field.

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Analysis and Algorithms for Service Parts Supply Chains

Services requiring parts has become a $1.5 trillion business annually worldwide, creating a tremendous incentive to manage the logistics of these parts efficiently by making planning and operational decisions in a rational and rigorous manner. This book provides a broad overview of modeling approaches and solution methodologies for addressing service parts inventory problems found in high-powered technology and aerospace applications. The focus in this work is on the management of high cost, low demand rate service parts found in multi-echelon settings. This unique book, with its breadth of topics and mathematical treatment, begins by first demonstrating the optimality of an order-up-to policy [or (s-1,s)] in certain environments. This policy is used in the real world and studied throughout the text. The fundamental mathematical building blocks for modeling and solving applications of stochastic process and optimization techniques to service parts management problems are summarized extensively. A wide range of exact and approximate mathematical models of multi-echelon systems is developed and used in practice to estimate future inventory investment and part repair requirements.

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Analysing Ecological Data

This book provides a practical introduction to analysing ecological data using real data sets collected as part of postgraduate ecological studies or research projects. The first part of the book gives a largely non-mathematical introduction to data exploration, univariate methods (including GAM and mixed modelling techniques), multivariate analysis, time series analysis (e.g. common trends) and spatial statistics. The second part provides 17 case studies, mainly written together with biologists who attended courses given by the first authors. The case studies include topics ranging from terrestrial ecology to marine biology.

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Analog-baseband architectures and circuits For multistandard and lowvoltage wireless transceivers

"Analog-Baseband Architectures and Circuits reviews the fundamentals and studies the state-of-the-art multistandard transceivers before describing novel architectural and circuit techniques for implementing multimode and wideband (tens of MHz) baseband analog front-ends under low-voltage constraints. Techniques developed on architecture level for efficient system-in-package (SiP) integration, testability and multi-standardability; and on circuit level for reducing the required supply voltage, power and area are generally applicable for most wireless systems, and are somewhat independent to technology scaling. Experimental 1-V baseband building blocks (i.e., double-quadrature-downconversion filter, programmable-gain amplifier and dc-offset canceler) and a 1-V fully-integrated receiver analog-baseband chain for IEEE 802.11a/b/g WLAN validate the techniques. The implementations are all in standard-VTH CMOS process, and no voltage boosting is required at any node." "Analog-Baseband Architectures and Circuits will be relevant to system architects, circuit designers, professors and students engaged in wireless transceiver front-ends research and development."

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Analisi matematica II : Teoria ed esercizi con complementi in rete = Mathematical analysis 2 : Theory and exercises with online complements

Intends to support a second teaching of Mathematical Analysis according to the principles of the new Didactic Regulations. It is especially designed for those study courses (such as Engineering, Computer Science, Physics) in which the mathematical tool is a significant part of the training. The fundamental concepts and methods of the differential and integral calculus of several variables, the series of functions and the ordinary differential equations are presented with the primary objective of training the student in their operational but critical use. The didactic setting of the text follows the one used for ANALYSIS I. The method of presentation of the arguments allows a flexible and modular use of the text, in order to respond to the various possible didactic choices in the organization of a Mathematical Analysis course.

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An Undergraduate Primer in Algebraic Geometry

This book consists of two parts. The first is devoted to an introduction to basic concepts in algebraic geometry: affine and projective varieties, some of their main attributes and examples. The second part is devoted to the theory of curves: local properties, affine and projective plane curves, resolution of singularities, linear equivalence of divisors and linear series, Riemann–Roch and Riemann–Hurwitz Theorems.The approach in this book is purely algebraic. The main tool is commutative algebra, from which the needed results are recalled, in most cases with proofs. The prerequisites consist of the knowledge of basics in affine and projective geometry, basic algebraic concepts regarding rings, modules, fields, linear algebra, basic notions in the theory of categories, and some elementary point–set topology.

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An R and S-Plus® Companion to Multivariate Analysis

Most data sets collected by researchers are multivariate, and in the majority of cases the variables need to be examined simultaneously to get the most informative results. This requires the use of one or other of the many methods of multivariate analysis, and the use of a suitable software package such as S-PLUS or R. In this book the core multivariate methodology is covered along with some basic theory for each method described. The necessary R and S-PLUS code is given for each analysis in the book, with any differences between the two highlighted.

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An Invitation to Abstract Mathematics

this book begins with a playful exploration of the building blocks of mathematics, such as definitions, axioms, and proofs. A study of the fundamental concepts of logic, sets, and functions follows, before focus turns to methods of proof. Having covered the core of a transition course, the author goes on to present a selection of advanced topics that offer opportunities for extension or further study. Throughout, appendices touch on historical perspectives, current trends, and open questions, showing mathematics as a vibrant and dynamic human enterprise.This second edition has been reorganized to better reflect the layout and curriculum of standard transition courses. It also features recent developments and improved appendices. An Invitation to Abstract Mathematics is ideal for those seeking a challenging and engaging transition to advanced mathematics, and will appeal to both undergraduates majoring in mathematics, as well as non-math majors interested in exploring higher-level concepts.

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An Introduction to Sobolev Spaces and Interpolation Spaces

After publishing an introduction to the Navier–Stokes equation and oceanography (Vol. 1 of this series), Luc Tartar follows with another set of lecture notes based on a graduate course in two parts, as indicated by the title. A draft has been available on the internet for a few years. The author has now revised and polished it into a text accessible to a larger audience.

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An Introduction to Queueing Theory: and Matrix-Analytic Methods

The present textbook contains the recordsof a two–semester course on que- ing theory, including an introduction to matrix–analytic methods. This book provides a mathematical introduction to the theory of queuing theory and matrix-analytic methods … . The style of the text … is concise and rigorous. The proofs are presented for study. Each chapter concludes with a set of exercises inviting readers to prove supplementary results and review particular aspects of the theory. The book under review attempts to give an introduction to the theory of queues without losing contact with its applicability. … For instructors who prefer the topics covered, this book is a nice candidate as they do not need to choose the topics but only need to elaborate on them. Nevertheless, it would be a good reference book for an introductory course in queuing theory, stochastic modelling, or applied probability

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