الصفحة 52
الصفحة 52
Analytical scientists in pharmaceutical product development : Task management and practical knowledge
Explains task management concepts and outlines practical knowledge to help pharmaceutical analytical scientists become productive and enhance their career. •Presents broad topics such as product development process, regulatory requirement, task and project management, innovation mindset, molecular recognition, separation science, degradation chemistry, and statistics. •Provokes thinking through figures, tables, and case studies to help understand how the various functions integrate and how analytical development can work efficiently and effectively by applying science and creativity in their work. •Discusses how to efficiently develop a fit-for-purpose HPLC method without screening dozens of columns, gradients, or mobile phase combinations each time, since the extra effort may not provide enough of a benefit to justify the cost and time in a fast-paced product development environment.
Analytic Methods for Design Practice
In the competitive world of modern engineering, rigorous and definite design methodologies are needed. However, many parts of engineering design are performed in either an ad-hoc manner or based on the intuition of the engineer.Analytic Methods for Design Practice is the first book to look at both stages of the design process – conceptual design and detailed design – and detail design methodologies for every step of the entire design process. The book introduces the following analytic design methodologies and explores their usefulness with many mathematical and practical examples: Axiomatic design; Optimization; Design of experiments; Robust design; Structural optimization; Dynamic response optimization; and Multidisciplinary optimization. A chapter of the book is devoted to case studies showing how practical design problems can be solved with analytic design methods based on Professor Park’s experiences of teaching design engineering over the past ten years.
Analysis by Its History
This book presents first-year calculus roughly in the order in which it first was discovered. The first two chapters show how the ancient calculations of practical problems led to infinite series, differential and integral calculus and to differential equations. The establishment of mathematical rigour for these subjects in the 19th century for one and several variables is treated in chapters III and IV. The text is complemented by a large number of examples, calculations and mathematical pictures and will provide stimulating and enjoyable reading for students, teachers, as well as researchers.
Analysing Ecological Data
This book provides a practical introduction to analysing ecological data using real data sets collected as part of postgraduate ecological studies or research projects. The first part of the book gives a largely non-mathematical introduction to data exploration, univariate methods (including GAM and mixed modelling techniques), multivariate analysis, time series analysis (e.g. common trends) and spatial statistics. The second part provides 17 case studies, mainly written together with biologists who attended courses given by the first authors. The case studies include topics ranging from terrestrial ecology to marine biology.
Analog and Pulse Circuits
Intended for anyone who has an interest to learn the analysis and design of analog and digital systems. The book covers the foundation of analysis and design of all analog and pulse circuits. The book is organized into seven chapters. In each chapter, practical derivations are explained step by step.
An Introduction to Soil Mechanics
Offers a superb introduction to theoretical and practical soil mechanics. Special attention is given to the risks of failure in civil engineering, and themes covered include stresses in soils, groundwater flow, consolidation, testing of soils, and stability of slopes. The basic principles of applied mechanics, that are frequently used, are offered in the appendices. The author’s considerable experience of teaching soil mechanics is evident in the many features of the book: it is packed with supportive color illustrations, helpful examples and references.
An Introduction to Scientific Computing : Twelve Computational Projects Solved with MATLAB
This book provides twelve computational projects aimed at numerically solving problems from a broad range of applications including Fluid Mechanics, Chemistry, Elasticity, Thermal Science, Computer Aided Design, Signal and Image Processing. For each project the reader is guided through the typical steps of scientific computing from physical and mathematical description of the problem, to numerical formulation and programming and finally to critical discussion of numerical results. Considerable emphasis is placed on practical issues of computational methods. The last section of each project contains the solutions to all proposed exercises and guides the reader in using the MATLAB scripts.
An Introduction to Network Programming with Java
This book provides an overview of Java … . Each chapter is supplemented with practical programming exercises.The combination of code templates with good supporting discussions allows a competent Java programmer to rapidly expand his or her skill base to include network programming.
An introduction to bioanalysis of biopharmaceuticals
Provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. Focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides.
An introduction to architectural conservation : Philosophy, legislation and practice
An Introduction to Architectural Conservation introduces non-specialist architects to the principles behind legislation concerning historic buildings. It is a practical guide to good working practice.
An Interactive Multimedia Introduction to Signal Processing
A didactic concept is undertaken for microelectronics, computer technology and communication engineering, which deals with the visualization of signals and processes in addition to graphical programming of signal processing systems. Through the utilization of a professional and globally supported software for metrology and control engineering, DasyLab, useful applications can be developed, modified and optimized. Computer supported processing of real signals is made possible over the sound card and the parallel port. Over two hundred pre-programmed signal engineering systems and design transparencies are provided. Pictures also play a dominant rule in this book: there are numerous introduction-videos, one for every chapter, more than 250 high-quality pictures and - most important – all the "living" experiments and their results are visualized. With this learning system, readers can now make use of "equipment" and software, which was practically unaffordable for individuals in the past. What's more, here is a very new concept for learning Signal Processing, not only from the physically-based scientific fundamentals, but also from the didactic perspective, based on modern results of brain research.
Ambisonics : A Practical 3D Audio Theory for Recording, Studio Production, Sound Reinforcement, and Virtual Reality
Provides a concise explanation of the fundamentals and background of the surround sound recording and playback technology Ambisonics. It equips readers with the psychoacoustical, signal processing, acoustical, and mathematical knowledge needed to understand the inner workings of modern processing utilities, special equipment for recording, manipulation, and reproduction in the higher-order Ambisonic format. The book comes with various practical examples based on free software tools and open scientific data for reproducible research. The book includes an extensive mathematical appendix. The book offers readers a deeper understanding of Ambisonic technologies, and will especially benefit scientists, audio-system and audio-recording engineers.
Alternatives to Animal Testing : Proceedings of Asian Congress 2016
This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs.
Alternative breast imaging : Four model-based approaches
Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible. Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS).
Allergic Diseases : Diagnosis and Treatment
In this updated third edition of the critically-acclaimed volume, expert physicians assemble user-friendly, clinically-oriented guides to aid in the day-to-day management of the allergic patient. With an emphasis on common allergic diseases and the pharmacological tools to control them, Allergic Diseases: Diagnosis and Treatment, Third Edition disseminates the practical knowledge that practitioners have accumulated through practice and teaching in the field of allergy and immunology.
Allelopathy in Sustainable Agriculture and Forestry
This book reports on the latest advances in allelopathy through the contributions of leading scientists in the field. The book addresses the history of allelopathy, the science of allelochemicals, and the application of allelopathy in agriculture and forestry. An emphasis on both methodology and application makes Allelopathy a truly practical reference for scientists, researchers and students of plant science, agriculture, forestry, terrestrial ecology and environmental science.
Aligner Techniques in Orthodontics
Filled with the theoretical and practical clinical information on the popular aligner techniques with a focus on Invisalign. Written by practicing orthodontists and noted experts on the topic, the book is designed to help practitioners develop their skills in using aligners in orthodontics. The authors describe in detail the clear and simple methods for treating patients using different aligner techniques, as well as material on treating any given malocclusion.
Aligner systems in invisible orthodontics: basic concepts and clinical management
Describes the processes, techniques and biomechanics involved in providing aligner treatment for different types of malocclusions. It opens with an overview of the material characteristics and the basic concepts of aligner therapy including topics like biocompatibility and intraoral deterioration. The main part of the book is dedicated to the various types of aligners, the methods used in their application and the practical aspects of delivery. It is structured based on the type of malocclusion being managed giving the reader a systematic pattern and a practical way of progressing through the book. The book closes with a discussion of the scientific data available.
Algorithms on Trees and Graphs : With Python Code
Introduces graph algorithms on an intuitive basis followed by a detailed exposition using structured pseudocode, with correctness proofs as well as worst-case analyses. Centered around the fundamental issue of graph isomorphism, the content goes beyond classical graph problems of shortest paths, spanning trees, flows in networks, and matchings in bipartite graphs. Advanced algorithmic results and techniques of practical relevance are presented in a coherent and consolidated way. Numerous illustrations, examples, problems, exercises, and a comprehensive bibliography support students and professionals in using the book as a text and source of reference. Furthermore, Python code for all algorithms presented is given in an appendix. Topics and features: Algorithms are first presented on an intuitive basis, followed by a detailed exposition using structured pseudocode / Correctness proofs are given, together with a worst-case analysis of the algorithms / Full implementation of all the algorithms in Python / An extensive chapter is devoted to the algorithmic techniques used in the book / Solutions to all the problems
Algorithms in Bioinformatics : Theory and Implementation
Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results
