الصفحة 5
الصفحة 5
Metal-containing molecules and nanomaterials : from diagnosis to therapy
Since the discovery and successful deployment of salvarsan to treat syphilis, as well as cisplatin as a cancer drug, the field of metallodrugs has been flourishing. In addition to therapeutic applications, metals and metal-containing molecules have properties, such as an electrochemical or an optical signal, used to diagnose biologically relevant molecules or unravel cellular metabolism. Metals are part of the essential elements for life, and of increased attention in nutraceuticals. Most of the current diagnosis processes, therapeutics and nutraceuticals are based on organic molecules. MILS-26 reviews the most recent metal-containing molecules and nanomaterials for diagnosis and therapy
Messenger RNA therapeutics
Focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine.
Mente e Cuore : Clinica psicologica della malattia cardiaca = Mind and heart : Psychological Clinic of Heart Disease
Recent data has shown that there is a relationship between psychological conditions and heart disease. Furthermore, psychological interventions on patients with coronary heart disease (CHD) can reduce heart risk and improve their quality of life. This volume, which is the result of collaboration with the most committed international researchers in the field of clinical psychology and health applied to heart disease, presents an updated and complete overview of scientific research in this area. The first part of the volume presents the psychological pictures and relational aspects associated with heart disease with a particular focus on personality traits. The second part illustrates the psychological interventions in cardiac rehabilitation that research has shown to be effective in reducing cardiac risk. This text can be a useful reference to the practice of doctors, psychologists and health professionals who want to understand and deepen the link between heart disease and psychological aspects.
Menopause
As people live longer, women are spending most of their lives in menopause, affected by a variety of estrogen-related conditions such as osteoporosis, cognitive and cardiovascular decline, increased risk of breast cancer and other symptoms that decrease the overall quality of life. Unfortunately, hormonal therapy was found to be less effective in decreasing the severity of some of these conditions than previously thought and may actually increase the risk of cancer. The aim of this research was to put a spotlight on natural treatments for menopause like changing life style and herbal medicines.
Medicinal plants for cosmetics : Health and diseases
Describes diseases and ailments occurring in individuals worldwide including acne, ageing, various cancers, eczema and other conditions. This book explains each disease and ailment, allowing the reader to gain a better perspective on misunderstood and underestimated assumptions accompanying the ailment or condition. Not only does this book present information on different diseases and ailments, it presents a variety of plants and plant-based compounds demonstrating potential health benefits.
Medicinal foods as potential therapies for type-2 diabetes and associated diseases : The chemical and pharmacological basis of their action
Focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. Provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries.
Medicina fisica e riabilitativa nei disturbi di equilibrio = Physical and rehabilitative medicine in balance disorders
Balance disorders are very common in the population: particularly frequent over the age of 40, are the first motivation for a medical examination after the age of 65 and frequently tend to become chronic. Balance disorders are symptoms of system dysfunction vestibular, complex sensory-psycho-motor system, whose task is that to control the activity of the antigravity muscles to maintain the erect station, of the oculomotor ones to allow the stabilization of the visual field during movement, and the neurovegetative functions they have relationship with standing and movement. Whether the vestibular system provides the information necessary for the check-up of the erect position, the rachis realizes it through a "stability dynamic ", allowed by its structural characteristics proprioception the spine is also a fundamental sensor for controlling balance ; therefore the techniques of physical and rehabilitative medicine and of manual medicine represent a powerful tool for curing ailments equilibrium. This volume comes from the comparison between a physiatrist and an audiologist, who for 15 years have integrated their clinical experience and therefore proposes a new one inter-specialist approach to the diagnostic and therapeutic problems of patients with balance disorders.
Medicina delletà prenatale : Prevenzione, diagnosi e terapia dei difetti congeniti e delle principali patologie gravidiche = Prenatal medicine: Prevention, diagnosis and therapy of congenital defects and the main pathologies of pregnancy
This text aims to respond to the actual need to bring together in a single and updated reference text notions and data from different backgrounds, all essential for optimal monitoring of pregnancy.
Medication problems and consequences due to the misuse of chronic drugs
All medicines can cause harm as well as benefit. Without systematic scientific evidence of benefit, no harmful effect, however rare, is worth the risk. This message is hardly revolutionary; it is one of the key principles of drug regulation Across all care environments, pharmacists play an essential role in the care of people who use and misuse of drug Medication history errors potentially clinically important, Improved physician training, accessible community pharmacy databases and closer teamwork between patients, physicians and pharmacists could reduce the frequency of these errors.
Medical Treatment of Intoxications and Decontamination of Chemical Agents in the Area of Terrorist Attack
This book includes reports which were presented at a NATO Advanced Research Workshop (ARW) entitled?Medical Treatment of Intoxications and Decontamination of Chemical Agent in the Area of Terrorist Attack?. The focus of this workshop was assessment of scientific concepts and practical means for management of chemical agent casualties in the area of terrorist attack with emphasis on improving the medical treatment and decontamination. These problems were analyzed from an interdisciplinary perspective. The primary objective of the ARW was to provide countries in which chemical-defense systems are currently under development with the experience and expertise of those that are more advanced and/or have already been exposed and responded to a chemical-terrorist attack. . The main areas covered were: 1. new approaches in pre-treatment and prophylaxis of nerve agent intoxication; 2. diagnosis of exposure to chemical agents ; 3. therapy of chemical agent intoxication; 4. development of personal decontamination; 5. decontamination of intoxication with chemical agents.
Medical Retina
Although the treatment of retinal diseases remains one of the most challenging fields in ophthalmology, the standard of knowledge has improved substantially over the past few years. The insight into basic mechanisms of disease has been expanded and novel diagnostic and therapeutic strategies have been developed, bridging the gap between laboratory and clinical science.
Medical Pharmacology and Therapeutics
Provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA. This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class. Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.
Medical image synthesis : Methods and clinical applications
Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties.
Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007; 10th International Conference, Brisbane, Australia, October 29 - November 2, 2007, Proceedings, Part II
The 10th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI2007, washeldattheBrisbaneConventionandExhibition Centre, South Bank, Brisbane, Australia from 29th October to 2nd November 2007. MICCAI has become a premier international conference in this domain, with in-depth papers on the multidisciplinary ?elds of biomedical image computing, computer assisted intervention and medical robotics.
Medical image computing and computer-assisted intervention – MICCAI 2007 ; 10th International Conference, Brisbane, Australia, October 29 - November 2, 2007, Proceedings, Part I
This title is part of a two-volume set that constitute the refereed proceedings of the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007.
Medical Decisions, Estrogen and Aging
This book is unique in that it integrates core findings from within the Decision Sciences and Evidence Based Medicine in light of the research that has been done on HT. Medical Decisions, Estrogen and Aging integrates the various components that go into medical decision making in the context of understanding the dilemmas that surround HT. Therefore this book is intended for both specialists and generalists in the field, and it is ideally suited for use by graduate and medical students, medical health care professionals, behavioral scientists, medical ethicists, gerontologists, historians of science, and endocrinologists.
Mechatronics and Machine Vision in Practice
From grading and preparing harvested vegetables to the tactile probing of a patient’s innermost recesses, mechatronics has become part of our way of life. The addition of senses and computing intelligence to blend with mechanical actuation gives rise to a breed of new machines with all the best attributes of a robot.
Mechanisms of Angiogenesis
Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which angiogenesis is either exaggerated (as in tumors) or too slow (as in ischemic diseases of heart and brain). Not surprisingly, pro- and antiangiogenic strategies have found their way into clinical trials. For instance, for the USA, the NIH website in early 2004 displayed 38 clinical studies involving either pro- or antiangiogenic th- apies. Given the expected overwhelming wealth of clinical data, the question may be asked whether further exploration of biological mechanisms is required or whether results from the bedside are instructive enough to proceed. This question depends also on the progress of pro- and antiangiogenic clinical trials. In the following, I give a short overview about some of the progress that has been made in this field. Since Judah Folkman proposed antiangiogenic tumor therapy thirty years ago, it has become increasingly evident that agents which interfere with blood vessel formation also block tumor progression. Accordingly, antiangiogenic therapy has gained much attention as a potential adjunct to conventional c- cer therapy.
Maxillofacial prosthetics and dental oncology : Practical approach from a high volume head and neck cancer centre
An assimilation of clinical and practical work done at Tata Memorial Hospital. It reflects the evolution of Dental Oncology and Maxillofacial Prosthodontics and more than 33 years of exclusive maxillofacial prosthodontic experience of Dr. Kanchan Dholam. This book covers the clinical guidelines for treatment, based on sound scientific principles and published literature. It also provides a step-by-step approach in the fabrication of commonly-indicated maxillofacial prostheses.
Irritable Bowel syndrome I.B.S
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder with a range of symptoms that significantly affect quality of life for patients. Is currently one of the most common disorders of the digestive system in the Western society? Almost 2 out of 10 people suffer from IBS, and it is associated with abdominal pain, bloating and altered stool consistency and imposes a heavy burden for the affected patients. The difficulty of differential diagnosis and its treatment may significantly delay initiation of optimal therapy. Hence, persons with IBS often self-treat symptoms with non-prescribed pharmacological regimens and/or complementary and alternative medicines (CAM) and by modifying diet and daily activities.
