الصفحة 5
الصفحة 5
Novel Plant Imaging and Analysis : Water, Elements and Gas, Utilizing Radiation and Radioisotopes
This book is only an introduction to show that radiation and radioisotopes (RI) are premier tools to study living plant physiology which leads to new findings. Who had ever imagined that we could see water in a plant? Who had ever imagined that we could see ions moving toward roots in solution? Who had ever imagined that we could see invisible gas (CO2) fixation and movement in a plant? These studies demonstrated for the first time that water, ions and gas can be visualized in living plants, which could be hardly seen by anyone before. This publication summarizes the results obtained by Nakanishi’s lab in The Univ. of Tokyo, based on her original concept and her original tools or systems. It is useful for professional scientists, plant physiologist, and those studying plant imaging.
Novel Optical Resolution Technologies
After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ment. Variousphysical methodsare capable of resolving the surface as wellas the insid estructure of crystalsat the atomiclevel while newhigh-performance computing resourcesafford thecapability of modeling the complexlarge-scale alignments necessary to simulatecrystallizationinrealsystems. Asaresult, the science of crystallization has shifted gradually fromstatic to dynamic science and considerable progress now underlies the complex but beautiful cryst- lization process.The vastpotential ofcrystallizationasan- portant feld ofscience isfar beyondthesimple technologyofpharmaceutical industries during the 20th century.
Novel mouse model for future autism research
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures in the first 3 years of life. It is not a single disorder, and it is broadly considered to be a multi-factorial disorder resulting from genetic and non-genetic risk factors and their interaction. Genetic studies of ASD have identified mutations that interfere with typical neurodevelopment in utero through childhood. These complexes of genes have been involved in synaptogenesis and axon motility. Recent developments in neuroimaging studies have provided many important insights into the pathological changes that occur in the brain of patients with ASD in vivo. Especially, the role of amygdala, a major component of the limbic system and the affective loop of the cortico-striatothalamo-cortical circuit, in cognition and ASD has been proved in numerous neuropathological and neuroimaging studies.
Novel Drug Delivery Systems for Chinese Medicines
Describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.
Novel drug delivery systems : Fundamentals and applications
Serves as a unique resource on the field of novel drug delivery systems (NDDSs). The evolving nature of diseases and the emergence of new health complications have driven a significant shift in drug therapy. Coupled with changes in human lifestyles and economic conditions, these factors have compelled the pharmaceutical industry to develop novel, efficient, and affordable drug products. The rise of promising technologies aimed at enhancing therapeutic performance further underscores the importance of novel drug delivery systems (NDDSs), making this field one of the most dynamic in pharmaceutical sciences today.
Novel Developments for Sustainable Hydropower
This book presents (selected) new and innovative developments for sustainable and fish-friendly hydropower. It offers unique insights into the challenges, practices and policies of hydropower developments across 8 European countries, providing examples from on-site studies and European-wide analyses. The case studies throughout the book are practical “real-world” examples, which are intended to serve as inspiration for anyone who would like to know more about how solutions for more sustainable hydropower production can be designed and implemented. Hydropower is an important renewable energy source, which, however, can also impact aquatic ecosystems, fish populations and hydro-morphology. EU and national water, environmental and energy legislation strive for sustainable energy and water resource management as well as the protection of important habitats and species. These have an effect on the requirements and decision making processes for hydropower planning, commissioning and operation. With a high variety of measures existing and site-specific conditions as well as national and EU level legal requirements to consider, it can be difficult to determine, what issues to address and which measures to implement.
Novel Carrier Systems for Targeted and Controlled Drug Delivery
Presents novel carrier systems for the targeted and controlled drug delivery for the treatment of various diseases which are difficult to be treated with conventional drug delivery systems like cancer, autoimmune disorders, and emerging infectious diseases. It also reviews the origins and applications of stimuli-responsive polymer systems and polymer therapeutics such as polymer-protein and polymer-drug conjugates. The book also explores the potential applications of the parenteral route of administration for the delivery of active pharmaceutical substances with a narrow therapeutic index and poor bioavailability. Further, the book presents common routes of administration for the systemic delivery of peptides and proteins. It also examines the applications of various implantable systems in drug delivery. The book also covers the important colloidal drug delivery systems, including liposomes and niosomes and solid lipid nanoparticles, and nanostructured lipid carriers.
Notch Signaling in Embryology and Cancer : Notch Signaling in Cancer
This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.
Northeast Asia : Ripe for Integration?
Can regional mechanisms better institutionalize the increasing complexity of economic and security ties among the countries in Northeast Asia? As the international state system undergoes dramatic changes in both security and economic relations in the wake of the end of the Cold War, the Asian financial crisis, and the attack of 9/11, this question is now at the forefront of the minds of both academics and policymakers. Still, little research has been done to integrate the analysis of security and economic analysis of changes in the region within a broader context that will give us theoretically-informed policy insights. Against this backdrop, this book investigates the origins and evolution of Northeast Asia's new institutional architecture in trade, finance, and security from both a theoretical and empirical perspective.
Nordic Mediation Research
Presents twelve unique studies on mediation from researchers in Denmark, Finland, Norway and Sweden, respectively. Each study highlights important aspects of mediation, including the role of children in family mediation, the evolution and ambivalent application of restorative justice in the Nordic countries, the confusion of roles in court-connected mediation, and the challenges in dispute systems.
Non-University Higher Education in Europe
This book represents the first-of-its-kind comprehensive discussion of the non-university higher education sector in Europe. Higher education throughout the world is facing rapid change. Despite the enormous attention devoted to that reality, this volume fills an important void. It describes and offers critical comparisons between the systems in 10 European countries. The book brings together the thinking of leading scholars on the non-university sectors in Austria, Belgium, Finland, Germany, Ireland, the Netherlands, Norway, Portugal, Spain, and the United Kingdom, with a chapter devoted to each country. National case studies are presented for the non-university sector in these countries that address issues such as historical developments, policy changes, governance structures, levels of institutional autonomy and future trends.
Non-spectral Asymptotic Analysis of One-Parameter Operator Semigroups
In this book, non-spectral methods are presented and discussed that have been developed over the last two decades for the investigation of asymptotic behavior of one-parameter operator semigroups in Banach spaces. This concerns in particular Markov semigroups in L1-spaces, motivated by applications to probability theory and dynamical systems. Recently many results on the asymptotic behaviour of Markov semigroups were extended to positive semigroups in Banach lattices with order-continuous norm, and to positive semigroups in non-commutative L1-spaces. Related results, historical notes, exercises, and open problems accompany each chapter.
Nonsmooth Variational Problems and their Inequalities : Comparison Principles and Applications
The main purpose of this book is to provide a systematic and unified exposition of comparison principles based on a suitably extended sub-supersolution method. This method is an effective and flexible technique to obtain existence and comparison results of solutions. Also, it can be employed for the investigation of various qualitative properties, such as location, multiplicity and extremality of solutions. In the treatment of the problems under consideration a wide range of methods and techniques from nonlinear and nonsmooth analysis is applied, a brief outline of which has been provided in a preliminary chapter in order to make the book self-contained.
NonlinearWaves and Solitons on Contours and Closed Surfaces
The present volume is an introduction to nonlinear waves and soliton theory in the special environment of compact spaces such a closed curves and surfaces and other domain contours. It assumes familiarity with basic soliton theory and nonlinear dynamical systems.
Nonlinear Waves : Classical and Quantum Aspects
Leading scientists discuss the most recent physical and experimental results in the physics of Bose-Einstein condensate theory, the theory of nonlinear lattices (including quantum and nonlinear lattices), and nonlinear optics and photonics. Classical and quantum aspects of the dynamics of nonlinear waves are considered. The contributions focus on the Gross-Pitaevskii equation and on the quantum nonlinear Schrödinger equation. Recent experimental results on atomic condensates and hydrogen bonded systems are reviewed. Particular attention is given to nonlinear matter waves in periodic potential.
Nonlinear Physical Oceanography : A Dynamical Systems Approach to the Large Scale Ocean Circulation and El Niño
Taken from a review of the first edition in SIAM:"This text is different from most others in that it combines several different disciplines and draws on many scientific studies in order to deduce mechanisms of ocean circulation.
Nonlinear Partial Differential Equations with Applications
This book primarily concerns quasilinear and semilinear elliptic and parabolic partial differential equations, inequalities, and systems. It balances the abstract functional-analysis approach based on nonlinear monotone, pseudomonotone, weakly continuous, or accretive mappings with concrete partial differential equations in their weak (or more general) formulation. Methods of Galerkin or of Rothe are exposed in a large generality. Other methods include various direct methods, regularization, or fixed points. The exposition leads general theory as fast as possible towards the analysis of concrete equations, which have specific applications in continuum (thermo-) mechanics of solids and fluids, electrically (semi-) conductive media, modelling of biological systems, or in mechanical engineering. Selected parts are rather an introduction into the subject while some others form an advanced textbook. The intended audience is graduate and PhD students and researchers in the theory of partial differential equations or in mathematical modelling of distributed parameter systems.
Nonlinear Partial Differential Equations for Scientists and Engineers
This expanded and revised second edition is a comprehensive and systematic treatment of linear and nonlinear partial differential equations and their varied applications. Building upon the successful material of the first book, this edition contains updated modern examples and applications from areas of fluid dynamics, gas dynamics, plasma physics, nonlinear dynamics, quantum mechanics, nonlinear optics, acoustics, and wave propagation. Methods and properties of solutions are presented, along with their physical significance, making the book more useful for a diverse readership.
Nonlinear Parabolic-Hyperbolic Coupled Systems and Their Attractors
This book presents recent results concerning the global existence in time, the large-time behaviour, decays of solutions and the existence of global attractors for some nonlinear parabolic-hyperbolic coupled systems of evolutionary partial differential equations arising from physics, mechanics and material science, such as the compressible Navier-Stokes equations, thermo(visco)elastic systems and elastic systems. To keep the book as self-contained as possible, the first chapter introduces to the needed results and tools from functional analysis, Sobolev spaces, differential and integral inequa.
Nonlinear Oscillations of Hamiltonian PDEs
After introducing the reader to classical finite-dimensional dynamical system theory, including the Weinstein–Moser and Fadell–Rabinowitz resonant center theorems,the author develops the analogous theory for completely resonant nonlinear wave equations. Within this theory, both problems of small divisors and infinite bifurcation phenomena occur, requiring the use of Nash–Moser theory as well as minimax variational methods. These techniques are presented in a self-contained manner together with other basic notions of Hamiltonian PDEs and number theory.
