Heterogeneity in statistical genetics : How to assess, address, and account for mixtures in association studies
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.
Healthy Longevity in China : Demographic, Socioeconomic, and Psychological Dimensions
China is aging at an extraordinary speed and has the largest quantity of elderly persons in the world. Scholars utilize this unprecedented living experience of human being and the unique Chinese Longitudinal Healthy Longevity Survey (CLHLS) datasets with the aim to answer in this volume the following questions critical to the aging population world wide. Is the period of disability compressing or expanding with increasing life expectancy and what factors are associated with these trends in the recent decades? Is it possible to realize morbidity compression with a prolongation of the life span in the future?The first section of the book presents the CLHLS project’s study design, sample distribution, contents of data collected, and assessments of age reporting and data quality. The remaining chapters are grouped into sections dealing with the demographic, social, economic, familial and psychological dimensions of healthy longevity.
Healthcare design basics
Delivers an up-to-date text covering the critical aspects of healthcare design, preparing students for a specialty rapidly growing in importance and size. includes: Step by step studio guidance outlining the basic design elements required for a wide range of ambulatory healthcare facilities and rooms Comprehensive explorations of the demands of new and improved healthcare facilities that meet the needs of an aging population Practical discussions of the space planning challenges involved in designing rooms and facilities for use during public health crises, including pandemics Dozens of full-color images that illustrate and highlight important concepts, examples, and design solutions
Health Promotion in Health Care – Vital Theories and Research
This book represents a vital contribution to global health education, offering insights into health promotion as part of patient care for bachelor’s and master’s students in health care (nurses, occupational therapists, physiotherapists, radiotherapists, social care workers etc.) as well as health care professionals, and providing an overview of the field of health science and health promotion for PhD students and researchers.
Health Dimensions of COVID-19 in India and Beyond
This book addresses the multiple health dimensions posed by the COVID-19 pandemic in India and other countries including nine in Asia, five in Sub-Saharan Africa, and New Zealand. It explores the impact of the pandemic on mental health, sexual and reproductive health and rights, health financing, self-care, and vaccine development and distribution. The contributing authors discuss its impact on vulnerable populations, including interstate migrants and female sex workers. The significant role of media and communications, rapid dissemination of information in social media, and its impact during the COVID-19 pandemic era are discussed. It closes with lessons learned from the experiences of countries that have contained the pandemic.
Health Communication
The effective communication of information on medical conditions and healthy lifestyles has played an important part in the improvement of the health status of the American population. At the same time, it is hard to ignore the negative impact that ineffective communication can have within the healthcare arena.communication. The benefits of good health communication are many, from better relationships between providers and patients to improved treatment compliance to reduced inequities of care.
Handbook of urban health : Populations, methods, and practice
As more people worldwide live in cities, increasingly we need to understand how cities and city living affect population health. Does city living negatively affect health? Conversely, can city living enhance population health and well-being? Over forty experts from around the world bring a depth of ideas to the Handbook of Urban Health, making the Handbook a focused resource for a range of health disciplines. A unique professional idea book, research resource, and teaching text, the Handbook of Urban Health challenges readers to consider the role that cities plays in shaping population health and to generate solutions that can make cities healthier places for all those who live there.
Handbook of topological fixed point theory
This book is the first in the world literature presenting all new trends in topological fixed point theory. Until now all books connected to the topological fixed point theory were devoted only to some parts of this theory. The content is also likely to stimulate the interest of mathematical economists, population dynamics experts as well as theoretical physicists exploring the topological dynamics.
Handbook of Population
The Handbook of Population is organized for classroom as well as reference use. It is divided into four sections – Population Structure, Population Processes, Population and the Social Sciences, and Applied Demography – and includes both an Introduction and an Epilogue by the editors. Part I, Population Structure, contains chapters on population size and growth, age and sex composition, marriage and family structure, and demographic analyses of gender, aging, race and ethnicity, and the labor force. Part II is focused on population processes, and includes chapters on fertility, infant and adult mortality, internal and international migration, and the demography of social stratification. Part III reflects the growing multidisciplinary nature of demography. Finally, Part IV recognizes the varied practical applications of demographic perspectives and data to national and global issues and problems.
Handbook of Intellectual and Developmental Disabilities
Changes within the interdisciplinary field of intellectual and developmental disabilities are evolving at a rapid pace. Clinicians, academics, administrators, and a variety of mental health providers alike need easy-to-access, reliable information that enables them to stay abreast of the numerous advances in research, assessment, treatment, and service delivery within a real-world sociopolitical framework. To that end, the Handbook of Intellectual and Developmental Disabilities is an essential resource for any professional who works with this vulnerable population. This volume examines in detail the numerous advances in the field, summarizing major domains and emerging subspecialties into one eminently useful reference.
Handbook of Homework Assignments in Psychotherapy : Research, Practice, and Prevention
The Handbook of Homework in Psychotherapy is the first resource for the practicing clinician that addresses the role of homework across major therapeutic paradigms and complex clinical problems. It opens with a series of practice-orientated chapters on the role of homework in different psychotherapies (acceptance and commitment, client-centered, constructivist, cognitive-behavioral, experiential, family, interpersonal, psychodynamic) written by an international team of expert psychotherapy practitioner-researchers. Then, experienced practitioners present strategies, examples, and formulated assignments for use with different populations (couples, families, older adults) and complex problems (chronic depression, chronic pain, eating disorders, obsessions and compulsions, personality disorders, psychosis, sexual dysfunction, substance abuse, traumatic brain injury). The Handbook closes with three chapters by leading psychotherapy theoreticians, researchers, and practitioners that critique the available research evidence for homework, integrate the recommendations for using homework in practice, and also provide directions for homework's role in prevention.
Handbook of healthcare in the Arab World
Examines health and medical care in the Arab world from a systems biology approach. It features comprehensive coverage that includes details of key social, environmental, and cultural determinants. In addition, the contributors also investigate the developed infrastructure that manages and delivers health care and medical solutions throughout the region. More than 25 sections consider all aspects of health, from cancer to hormone replacement therapy, from the use of medications to vitamin deficiency in emergency medical care. Chapters highlight essential areas in the wellbeing and care of this population. These topics include women’s health care, displaced and refugee women’s health needs, childhood health, social and environmental causes of disease, health systems and health management, and a wide range of diseases of various body systems. This resource also explores issues related to access and barriers to health delivery throughout the region.
Handbook of Evidence-Based Therapies for Children and Adolescents : Bridging Science and Practice
Growing numbers of young people—some 10% to 20% of school-age populations—have mental health problems requiring intervention, and current policy initiatives identify evidence-based therapies as the most effective and relevant forms of treatment. By reviewing evidence-based treatments (EBTs) across a wide spectrum of conditions, the Handbook of Evidence-Based Therapies for Children and Adolescents: Bridging Science and Practice closes the gaps between children’s needs and services as well as those between research, training, and practice, Several EBT options, both proved and promising, are offered for each covered disorder and are bolstered by case examples, tables, and reference lists. Features include chapters on implementation issues such as diversity, family treatment, assessment strategies, and community settings, and step-by-step guidance for the researcher looking to gather empirical support for therapies.
Handbook of Drug Abuse Prevention
This wide-ranging handbook brings together experts in the sociology of drug abuse prevention. Providing a comprehensive overview of the accumulated knowledge on prevention theory, intervention design, and development and prevention research methodology, this work also promotes prevention science as an evolving field in the practice and policy of drug abuse prevention.Included are sections on Theoretical and Empirical Foundations, Social Contexts of Prevention, Prevention as Social Control, Special Populations, Research Design and a Look at the Future.
Handbook of Diabetes Management
Over 18 million Americans are afflicted. Nearly as many are at risk. Diabetic conditions account for one-fifth of the nation’s chronic health care burden. A public health crisis of this magnitude demands professional resources that apply evidence-based practical knowledge and anticipate the challenges that lie ahead. The Handbook of Diabetes Management is one such reference, addressing the complexity of the disease, the diversity of the populations it affects, and the continued improvement of care systems.
Handbook of consumer finance research
Debt consolidation…pension givebacks…Social Security under siege…bankruptcies and foreclosures…Americans’ financial lives are fraught with issues, challenges, and potential threats, in record numbers. The Handbook of Consumer Finance Research surveys the social aspects of consumer behavior, offering latest data and original research on current consumer needs as well as identifying emerging areas of research. This accessible volume (which can be read without advanced training in the field) starts with current concepts of risk tolerance, consumer socialization, and financial well-being, and moves on to salient data on specific settings and populations
Groundwater Dynamics in Hard Rock Aquifers : Sustainable Management and Optimal Monitoring Network Design
Groundwater is of utmost importance in the arid and semi-arid environment. The areas in such regions are forced to face a variety of problems regarding groundwater as it is the main source of water no matter for any use viz., drinking, domestic, irrigation or industrial particularly for the rural population. The main challenges in hard rock areas in the semi-arid region are the water conservation, management and planning of the water resources. This is further complicated with several complexities of the geological formation. With the semi-arid environment, complex geological settings and over shooting stresses, the aquifer system becomes extremely fragile and sensitive. In spite of a good amount of research in this field, it is still needed to understand the behaviour of such complex system precisely and also apply the result in reasonably larger scales.
Groundwater and Ecosystems
Groundwater Dependent Ecosystems (GDEs) frequently exhibit rich biological diversity and can provide enormous economic wealth. In recent years, GDEs in many industrialized countries have shown signs of serious degradation, primarily the result of groundwater abstraction and pollution. Many such systems, including a number of well documented cases in Eastern Europe, are no longer sustainable. As a consequence, the conservation and sustainable management of GDEs has emerged as one of the most urgent environmental research priorities of our time. A large percentage of the world’s population lives in cities and either depends on, or is affected in some way, by groundwater. Moreover, groundwater has become a very important and complex issue that attracts the interest of many diverse stakeholders. Many problems related to groundwater and ecosystems are shared by countries throughout the world and there is growing recognition that much can be gained by co-operation on an international scale.
Groundwater : Resource evaluation, augmentation, contamination, restoration, modeling and management
The demand for water resources is increasing day by day due to ever increasing population, mostly from developing countries. This has resulted in abstracting more water from the subsurface stratum and forcing the water managers to manage the limited groundwater resources in a more scientific way, which in turn needs a more sophisticated way of assessing the underground resource and manage it optimally.
Grid computing in life science ; 1st International Workshop on Life Science Grid, LSGRID 2004 Kanazawa, Japan, May 31-June 1, 2004, Revised Selected and Invited Papers
Researchers in the ?eld of life sciences rely increasingly on information te- nology to extract and manage relevant knowledge. The complex computational and data management needs of life science research make Grid technologies an attractive support solution. However, many important issues must be addressed before the Life Science Grid becomes commonplace. The 1st International Life Science Grid Workshop (LSGRID 2004) was held in Kanazawa Japan, May 31–June 1, 2004. This workshop focused on life s- ence applications of grid systems especially for bionetwork research and systems biology which require heterogeneous data integration from genome to phenome, mathematical modeling and simulation from molecular to population levels, and high-performance computing including parallel processing, special hardware and grid computing.



















