الصفحة 5
الصفحة 5
Novel Drug Delivery Systems for Chinese Medicines
Describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.
Novel Carrier Systems for Targeted and Controlled Drug Delivery
Presents novel carrier systems for the targeted and controlled drug delivery for the treatment of various diseases which are difficult to be treated with conventional drug delivery systems like cancer, autoimmune disorders, and emerging infectious diseases. It also reviews the origins and applications of stimuli-responsive polymer systems and polymer therapeutics such as polymer-protein and polymer-drug conjugates. The book also explores the potential applications of the parenteral route of administration for the delivery of active pharmaceutical substances with a narrow therapeutic index and poor bioavailability. Further, the book presents common routes of administration for the systemic delivery of peptides and proteins. It also examines the applications of various implantable systems in drug delivery. The book also covers the important colloidal drug delivery systems, including liposomes and niosomes and solid lipid nanoparticles, and nanostructured lipid carriers.
Novel Biotechnologies for Biocontrol Agent Enhancement and Management
This multidisciplinary group, having backgrounds in the diff- ent aspects of biotechnologies (transgenic enhancement, molecular biology, formulation, genetics, risk assessment, new technology, biochemistry, and physiology), presented highly advanced lectures during the 10-day-ASI, in order to allow students to improve their capability to enhance and manage - ological control agents. This approach will allow ASI attendees to bring new ideas, new approaches, or new methodologies coming from different ?elds of application to their own ?eld of expertise.
Novel algorithms and techniques In telecommunications, automation and industrial electronics
Novel Algorithms and Techniques in Telecommunications, Automation and Industrial Electronics includes a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of Industrial Electronics, Technology & Automation, Telecommunications and Networking.
Norwegian Shipping in the 20th Century : Norway's Successful Navigation of the World's Most Global Industry
This open access book discusses how Norwegian shipping companies played a crucial role in global shipping markets in the 20th century, at times transporting more than ten per cent of world seaborne trade. Chapters explore how Norway managed to remain competitive, despite being a high labour-cost country in an industry with global competition. Among the features that are emphasised are market developments, business strategies and political decisions The Norwegian experience was shaped by the main breaking points in 20th century world history, such as the two world wars, and by long-term trends, such as globalization and liberalization. The shipping companies introduced technological and organizational innovations to build or maintain a competitive advantage in a rapidly changing world. The growing importance of offshore petroleum exploration in the North Sea from the 1970s was both a threat and an opportunity to the shipping companies. By adapting both business strategies and the political regime to the new circumstances, the Norwegian shipping sector managed to maintain a leading position internationally.
Northern Lights on Civic and Citizenship Education : A Cross-national Comparison of Nordic Data from ICCS
This book presents an in depth analysis of data from ICCS. An international group of scholars critically address the state of civic and citizenship education in the four Nordic countries that participated in the IEA International Civic and Citizenship Education Study (ICCS) in 2009 and 2016. The findings are of particular relevance to educators at all levels, from school education through to teacher education.
Northeast Asia : Ripe for Integration?
Can regional mechanisms better institutionalize the increasing complexity of economic and security ties among the countries in Northeast Asia? As the international state system undergoes dramatic changes in both security and economic relations in the wake of the end of the Cold War, the Asian financial crisis, and the attack of 9/11, this question is now at the forefront of the minds of both academics and policymakers. Still, little research has been done to integrate the analysis of security and economic analysis of changes in the region within a broader context that will give us theoretically-informed policy insights. Against this backdrop, this book investigates the origins and evolution of Northeast Asia's new institutional architecture in trade, finance, and security from both a theoretical and empirical perspective.
Non-Vitamin K Antagonist Oral Anticoagulants : A Concise Guide
An essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.
Non-viral Gene Therapy: Gene Design and Delivery
The development of gene medicine based on the concept of molecular therapy has opened new medical horizons. Among the many techniques in gene medicine, gene design and delivery are especially significant in clinical applications. This book presents state-of-the-art information on non-viral gene-delivery techniques, covering a broad spectrum of disciplines that include chemistry, molecular biology, cell biology, and pharmacokinetics
Nonsmooth Variational Problems and their Inequalities : Comparison Principles and Applications
The main purpose of this book is to provide a systematic and unified exposition of comparison principles based on a suitably extended sub-supersolution method. This method is an effective and flexible technique to obtain existence and comparison results of solutions. Also, it can be employed for the investigation of various qualitative properties, such as location, multiplicity and extremality of solutions. In the treatment of the problems under consideration a wide range of methods and techniques from nonlinear and nonsmooth analysis is applied, a brief outline of which has been provided in a preliminary chapter in order to make the book self-contained.
Nonsmooth Mechanics and Analysis : Theoretical and Numerical Advances
Nonsmooth mechanics concerns mechanical situations with possible nondifferentiable relationships, eventually discontinuous, as unilateral contact, dry friction, collisions, plasticity, damage, and phase transition. The basis of the approach consists in dealing with such problems without resorting to any regularization process. Indeed, the nonsmoothness is due to simplified mechanical modeling; a more sophisticated model would require too large a number of variables, and sometimes the mechanical information is not available via experimental investigations. Therefore, the mathematical formulation becomes nonsmooth; regularizing would only be a trick of arithmetic without any physical justification. Nonsmooth analysis was developed, especially in Montpellier, to provide specific theoretical and numerical tools to deal with nonsmoothness. It is important not only in mechanics but also in physics, robotics, and economics.
Nonsmooth Analysis
The book treats various concepts of generalized derivatives and subdifferentials in normed spaces, their geometric counterparts (tangent and normal cones) and their application to optimization problems. It starts with the subdifferential of convex analysis, passes to corresponding concepts for locally Lipschitz continuous functions and finally presents subdifferentials for general lower semicontinuous functions. All basic tools are presented where they are needed; this concerns separation theorems, variational and extremal principles as well as relevant parts of multifunction theory. The presentation is rigorous, with detailed proofs. Each chapter ends with bibliographic notes and exercises.
Nonparametric Functional Data Analysis : Theory and Practice
Modern apparatuses allow us to collect samples of functional data, mainly curves but also images. On the other hand, nonparametric statistics produces useful tools for standard data exploration. This book links these two fields of modern statistics by explaining how functional data can be studied through parameter-free statistical ideas. This book starts from theoretical foundations including functional nonparametric modeling, description of the mathematical framework, construction of the statistical methods, and statements of their asymptotic behaviors. It proceeds to computational issues including R and S-PLUS routines. Several functional datasets in chemometrics, econometrics, and pattern recognition are used to emphasize the wide scope of nonparametric functional data analysis in applied sciences. The companion Web site includes R and S-PLUS routines, command lines for reproducing examples presented in the book, and the functional datasets. Rather than set application against theory, this book is really an interface of these two features of statistics. A special effort has been made in writing this book to accommodate several levels of reading.
Nonparametric Bayesian Learning for Collaborative Robot Multimodal Introspection
This book focuses on robot introspection, which has a direct impact on physical human–robot interaction and long-term autonomy, and which can benefit from autonomous anomaly monitoring and diagnosis, as well as anomaly recovery strategies.
Nonlinear Time Series Analysis in the Geosciences : Applications in Climatology, Geodynamics and Solar-Terrestrial Physics
This book presents recent developments in nonlinear time series which have been motivated by present day problems in geosciences. Modern methods of spatio-temporal data analysis, time-frequency analysis, dimension analysis, nonlinear correlation and synchronization analysis and other nonlinear concepts are used to study emerging questions in climatology, geophysics, solar-terrestrial physics and related scientific disciplines. This volume collects contributions of some of the world's leading experts in geoscientific time series analysis.
Nonlinear Physical Oceanography : A Dynamical Systems Approach to the Large Scale Ocean Circulation and El Niño
Taken from a review of the first edition in SIAM:"This text is different from most others in that it combines several different disciplines and draws on many scientific studies in order to deduce mechanisms of ocean circulation.
Nonlinear Partial Differential Equations with Applications
This book primarily concerns quasilinear and semilinear elliptic and parabolic partial differential equations, inequalities, and systems. It balances the abstract functional-analysis approach based on nonlinear monotone, pseudomonotone, weakly continuous, or accretive mappings with concrete partial differential equations in their weak (or more general) formulation. Methods of Galerkin or of Rothe are exposed in a large generality. Other methods include various direct methods, regularization, or fixed points. The exposition leads general theory as fast as possible towards the analysis of concrete equations, which have specific applications in continuum (thermo-) mechanics of solids and fluids, electrically (semi-) conductive media, modelling of biological systems, or in mechanical engineering. Selected parts are rather an introduction into the subject while some others form an advanced textbook. The intended audience is graduate and PhD students and researchers in the theory of partial differential equations or in mathematical modelling of distributed parameter systems.
Nonlinear Partial Differential Equations for Scientists and Engineers
This expanded and revised second edition is a comprehensive and systematic treatment of linear and nonlinear partial differential equations and their varied applications. Building upon the successful material of the first book, this edition contains updated modern examples and applications from areas of fluid dynamics, gas dynamics, plasma physics, nonlinear dynamics, quantum mechanics, nonlinear optics, acoustics, and wave propagation. Methods and properties of solutions are presented, along with their physical significance, making the book more useful for a diverse readership.
Nonlinear Optical Crystals : A Complete Survey
Nonlinear optical crystals are widely used in modern optical science and technology for frequency conversion of laser light, i.e. to generate laser radiation at any specific wavelength in visible, UV or IR spectral regions. This unrivalled reference book contains the most complete and up-to-date information on properties of nonlinear optical crystals. It includes: * Database of 63 common and novel nonlinear optical crystals * Periodically-poled and self-frequency-doubling materials * Full description of linear and nonlinear optical properties * Significant amount of crystallophysical, thermophysical, spectroscopic, electro-optic and magneto-optic information * 7 mini-reviews on novel applications, such as deep-UV light generation, terahertz-wave generation, ultrashort laser pulse compression, photonic band-gap crystals, x3 nonlinearity, etc. * More than 1500 different references with full titles It is a vital source of information for scientists and engineers dealing with modern applications of nonlinear optical crystals in quantum electronics, photonics, optoelectronics and laser physics.
Nonlinear Integer Programming
It is not an exaggeration that much of what people devote in their hfe re solves around optimization in one way or another. On one hand, many decision making problems in real applications naturally result in optimization problems in a form of integer programming. On the other hand, integer programming has been one of the great challenges for the optimization research community for many years, due to its computational difficulties: Exponential growth in its computational complexity with respect to the problem dimension. This book addresses the topic of the general nonlinear integer programming (NLIP). The overall goal of the book is to bring the state of the art of the theoretical foundations and solution methods of NLIP to readers who are interested in optimization, operations research and computer science. This book investigates the theory and solution methodologies for the general NLIP and provides the developments
