الصفحة 5
الصفحة 5
Heterocyclic Antitumor Antibiotics
Heterocyclic Compounds Includes aspects such as synthesis, reaction mechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical studies, pharmacological aspects, applications in material sciences etc. Metabolism will be also included which will provide information useful in designing pharmacologically active agents. Pathways involving destruction of heterocyclic ring will also be dealt with so that synthesis of specifically functionalized non-heterocyclic molecules can be designed. Overall scope is to cover topics dealing with most of the areas of current trends in heterocyclic chemistry which will suit to a larger heterocyclic community.
Herbals as nutraceuticals : Their role in healthcare
Herbal nutraceuticals demonstrate a variety of therapeutic benefits and have been found to prevent, treat, and even cure a range of diseases. This new book provides insight into nutraceuticals and their function in human health, highlighting their antimicrobial and immune-inflammatory properties. It describes the nutraceutical properties of various medicinal herbs and details the role of nutraceuticals in treating diseases such as Alzheimer's, Parkinson's, obesity, diabetes, cancer, cardiovascular diseases, skincare issues, and more.
HDPE Geomembranes in Geotechnics
HDPE (High-density polyethylene) geomembranes are nowadays widely used for large-area liners and construction sealings in geotechnical engineering. Lining of water ponds, dams and dykes, landfill base liners and cover systems, remediation of contaminated sites, waterproof for tunnels, beneath highways and for various other civil engineering constructions are a few examples of application. The book covers all aspects of the HDPE geomembrane field: HDPE materials, geomembrane manufacture, textured geomembranes, properties, long-term performance and testing, installation and welding of geomembranes, quality assurance and control, leak detection, standards, recommendations and regulations. Various important topics are treated in detail. As part of it, the basic physical and chemical facts necessary to fully understand HDPE geomembrane properties and performance are carefully developed and explained.
Handbook Utility Management
As the deregulation of European utility markets has progressed, the dynamics of and the competitive pressure in the utility industries have steadily intensified over recent years. These changes in the regulatory framework have caused a shift in the direction of an integrated market environment, resulting in new challenges for the management of power and gas companies and a substantial need for strategic reorientation. The Handbook Utility Management is concerned with these changes and challenges in the utility industries and emerging managerial issues of high practical relevance. Inclusion of the latest insights into the economic, technological, and legal drivers of the diverse value chain activities makes the Handbook a valuable asset for both professionals and researchers.
Handbook of Pathogens and Diseases in Cephalopods
The aim of this book is to facilitate the identification and description of the different organs as well as pathogens and diseases affecting the most representative species of cephalopods focussed on Sepia officinalis, Loligo vulgaris and Octopus vulgaris. These species are valuable ‘morphotype’ models and belong to the taxonomic groups Sepioidea, Myopsida and Octopoda, which include most of the species with a high market value and aquaculture potential. The study is based on photographs at macroscopic and histological level in order to illustrate the role of the most important pathogens and related diseases from the view of a pathological diagnosis. The reader is able to familiarize with functional anatomy, necropsy and general histology of adults and paralarvae, as well as with the identification of different pathogens and pathologies. This work is thus an invaluable guide for the diagnosis of cephalopod diseases. Besides including pathogens for non-European cephalopod species, it also provides a useful contribution encouraging marine pathologists, parasitologists, veterinarians and those involved in fishery sanitary assessments, aquarium maintenance and aquaculture practices aiming to increase their knowledge about the pathology of cephalopods.
Handbook of medicinal plants of the world for aging : Botany, ethnopharmacology, natural Products, and molecular pathways
Provides an unprecedented comprehensive overview of more than 100 plants used globally as medicine with the potential to prevent premature aging. It is covers the pathophysiology of aging from the molecular and cellular to the organ levels, as well as the current state of knowledge about the modes of action of natural products from plants on the pathophysiological pathways related to the (i) cardiovascular system and metabolism, (ii) central nervous system, (iii) kidneys, (iv) bones, (v) skin and hair, and (vi) immune system.
Handbook of Behavioral and Emotional Problems in Girls
Psychopathology in children and adolescents has been extensively researched and addressed in terms of its epidemiology, expression, developmental pathways, and causes. And despite all the research studies and findings, the question remained: Are the emotional and behavioral problems of girls unique to the distinct aspects of female development, behavior, and adjustment? To fully understand and address the emotional and behavioral problems of girls, their distinct characteristics must be examined in terms of both developmental progression and context—that is, in terms of their various ethnic, cultural, socioeconomic backgrounds as well as family, school, and peer environments and influences.
Habitats and Biota of the Gulf of Mexico : Before the deepwater horizon oil spill ; Vol.2 : Fish resources, fisheries, sea turtles, avian resources, marine mammals, diseases and mortalities
The Gulf of Mexico is an open and dynamic marine ecosystem rich in natural resources but heavily impacted by human activities, including agricultural, industrial, commercial and coastal development. Nutrients and pollutants from coastal communities and dozens of rivers flow into the Gulf, including material from the Mississippi River watershed, which drains over one third of continental United States. The Gulf of Mexico has been continuously exposed to petroleum hydrocarbons for millions of years from natural oil and gas seeps on the sea floor, and more recently from oil drilling and production activities located in the water near and far from shore. Major accidental oil spills in the Gulf are infrequent; two of the most significant include the Ixtoc I blowout in the Bay of Campeche in 1979 and the Deepwater Horizon Oil Spill in 2010.
Habitats and Biota of the Gulf of Mexico : Before the deepwater horizon oil spill ; Vol.1 : Water quality, sediments, sediment contaminants, oil and gas Seeps, coastal habitats, offshore plankton and benthos, and shellfish
The Gulf of Mexico is an open and dynamic marine ecosystem rich in natural resources but heavily impacted by human activities, including agricultural, industrial, commercial and coastal development. Nutrients and pollutants from coastal communities and dozens of rivers flow into the Gulf, including material from the Mississippi River watershed, which drains over one third of continental United States. The Gulf of Mexico has been continuously exposed to petroleum hydrocarbons for millions of years from natural oil and gas seeps on the sea floor, and more recently from oil drilling and production activities located in the water near and far from shore. Major accidental oil spills in the Gulf are infrequent; two of the most significant include the Ixtoc I blowout in the Bay of Campeche in 1979 and the Deepwater Horizon Oil Spill in 2010.
Gut orchestra : Micro-symphony turned onco-cacophony
The role of microbiota in colorectal cancer has been studied since alterations in its composition were observed. Ever since, there are more and more pieces of evidence that microbiota could be implicated in colorectal cancer progression. Thus, the components of the microbiota could be biomarkers for the diagnosis and prognosis of colorectal cancer. It is truly important to address how the microbiota interacts with the host and how the host shapes the microbiota, in order to understand the biological pathways and mechanisms involved in their relationship and the consequences of their interactions in colorectal cancer.
Groundwater Recharge from Run-off, Infiltration and Percolation
This book first discusses the recharge fluxes relating both to the quantity and quality of groundwater. In order to face the threats to the water supply and to be able to maintain a sustainable water management policy, detailed knowledge is needed in between others on the surface to subsurface transformation link in the water cycle. Secondly, the presentation and comparison of both the traditional and modern approach to determine groundwater recharge is discussed. The traditional approach to determine groundwater recharge, is based on water balance estimates and hydraulic considerations, which yield instantaneous values at best but do not integrate the totality of recharge pathways in time and space. In contrast, environmental tracers do integrate these factors. Finally, the fate of groundwater recharge in the subsurface by hydraulic and geologic means is discussed in detail, in order to stimulate adapted groundwater management strategies and to better assess consequences of climate changes on groundwater resources as a whole.
Ground bearing concrete slabs : Specification, design, construction and behaviour
Ground bearing concrete floors, industrial concrete hardstandings and concrete highway pavements have not, in the past, been perceived as a single type of structural element and their construction has taken place independently of each other. This is in spite of their obvious commonality in the areas of design, materials, geotechnical appreciation and construction.
Governance of Arctic Shipping : Rethinking Risk, Human Impacts and Regulation
This is a result of the Dalhousie-led research project Safe Navigation and Environment Protection, supported by a grant from the Ocean Frontier Institute’s the Canada First Research Excellent Fund (CFREF).
Global Pathways to Education : Cultural Spheres, Networks, and International Organizations
The research presented in this volume is a wide-ranging analysis and explanation of the dynamics of emergence, diffusion, and change in relation to state education systems. The chapters offer an empirical investigation into whether the global diffusion of Western-rational educational content and organizational forms occurs as expected by neoinstitutionalist theory, or whether culturally specific developmental paths dominate in different parts of the world.
Global optimization and constraint satisfaction ; 2nd International Workshop, COCOS 2003, Lausanne, Switzerland, Nevember 18-21, 2003, Revised Selected Papers
Theformulationofmanypracticalproblemsnaturallyinvolvesconstraintsonthe variables entering the mathematical model of a real-life situation to be analyzed. It is of great interest to ?nd the possible scenarios satisfying all constraints, and, iftherearemanyofthem,eitherto?ndthebestsolution,ortoobtainacompact, explicit representation of the whole feasible set. The 2nd Workshop on Global Constrained Optimization and Constraint S- isfaction, COCOS 2003, which took place during November 18–21, 2003 in L- sanne, Switzerland, was dedicated to theoretical, algorithmic, and application oriented advances in answering these questions. Here global optimization refers to ?nding the absolutely best feasible point, while constraint satisfaction refers to?ndingallpossiblefeasiblepoints.AsinCOCOS2002,the?rstsuchworkshop (see the proceeedings [1]), the emphasis was on complete solving techniques for problems involving continuous variables that provide all solutions with full rigor, and on applications which, however, were allowed to have relaxed standards of rigor.
Geometric Function Theory : Explorations in Complex Analysis
Complex variables is a precise, elegant, and captivating subject. Presented from the point of view of modern work in the field, this new book addresses advanced topics in complex analysis that verge on current areas of research, including invariant geometry, the Bergman metric, the automorphism groups of domains, harmonic measure, boundary regularity of conformal maps, the Poisson kernel, the Hilbert transform, the boundary behavior of harmonic and holomorphic functions, the inhomogeneous Cauchy–Riemann equations, and the corona problem.
Geography and Drug Addiction
لإhis book contains drug addiction contributes to better understanding the etiology of addiction, its diffusion, its interaction with geographically variable environmental, social, and economic factors, and the strategies for its treatment and prevention. This book explores links between geography and drug abuse and identifies research ideas, connections, and research pathways which point to some promising avenues for future work in this area
Genetic programming IV : Routine human-competitive machine intelligence
Genetic Programming IV: Routine Human-Competitive Machine Intelligence presents the application of GP to a wide variety of problems involving automated synthesis of controllers, circuits, antennas, genetic networks, and metabolic pathways. The book describes fifteen instances where GP has created an entity that either infringes or duplicates the functionality of a previously patented 20th-century invention, six instances where it has done the same with respect to post-2000 patented inventions, two instances where GP has created a patentable new invention, and thirteen other human-competitive results. The book additionally establishes: GP now delivers routine human-competitive machine intelligence GP is an automated invention machine GP can create general solutions to problems in the form of parameterized topologies GP has delivered qualitatively more substantial results in synchrony with the relentless iteration of Moore's Law
Genetic programming : Theory and practice II
This volume explores the emerging interaction between theory and practice in the cutting-edge, machine learning method of Genetic Programming (GP). The contributions developed from a second workshop at the University of Michigan's Center for the Study of Complex Systems where leading international genetic programming theorists from major universities and active practitioners from leading industries and businesses met to examine how GP theory informs practice and how GP practice impacts GP theory. Chapters include such topics as financial trading rules, industrial statistical model building, population sizing, the roles of structure in problem solving by computer, stock picking, automated design of industrial-strength analog circuits, topological synthesis of robust systems, algorithmic chemistry, supply chain reordering policies, post docking filtering, an evolved antenna for a NASA mission and incident detection on highways.
Genetic control of neuronal migrations in human cortical development
Introduction Cortical development is a complex, tightly regulated process that eventually leads to the six-layered adult human neocortex, the substrate of the unique cognitive, emotional, and social abilities of our species. The basic mechanisms of early cortical development are believed to be very similar among mammals, which has led to a tendency of extrapolating experimental data from rodents on humans.
