الصفحة 5
الصفحة 5
Fundamentals of Clinical Data Science
This book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare.
Frontiers in Anti-Infective Drug Discovery ; Vol.9
Covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs
From Principles of Learning to Strategies for Instruction-with Workbook Companion : A Needs-Based Focus on High School Adolescents
The first part of this volume is a reprint of the original book, which highlights principles of learning which have been synthesized from research literature in psychology. The second part of this volume is a newly-developed Companion Workbook focusing solely on developing instructional strategies for high school level adolescents.
Fragmented Intimacy : Addiction in a Social World
Fragmented Intimacy transcends familiar concepts of addiction by focusing not on addicts in isolation but on the social contexts that are disrupted and on the struggle that affects all those involved as they attempt to regroup and initiate change. Applicable to drugs, alcohol, and gambling, this engagingly written book offers both innovative theory and practice-strengthening interventions.
Foundations of Sport-Related Brain Injuries
A major take-home point from this book should be the assumption that symptom resolution does not necessarily mean injury resolution. As can be seen by research focusing on global metabolic cascades and neural activity of the brain, long-standing dysfunctional pathways continue to exist for extended periods of time even after a minor concussion. Until we completely understand the consequences of short-term perturbations and long-term residual brain dysfunctions, concussions must be treated with respect and given a higher priority for continued research activity.
Fostering transformative change for sustainability in the context of socio-ecological production landscapes and seascapes (SEPLS)
This book is a compilation of case studies that provide useful knowledge and lessons that derive from on-the-ground activities and contribute to policy recommendations, focusing on the relevance of social-ecological production landscapes and seascapes (SEPLS) to “transformative change.” The concept of “transformative change” has been gaining more attention to deal with today’s environmental and development problems, whereas both policy and scientific communities have been increasingly calling for transformative change toward sustainable society. The Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) has planned to start the so-called “assessment on transformative change” if approved by the IPBES plenary to be held in 2021
Formal Models of Communicating Systems : Languages, Automata, and Monadic Second-Order Logic
This book studies the relationship between automata and monadic second-order logic, focusing on classes of automata that describe the concurrent behavior of distributed systems.
Foreign Investor Misconduct in International Investment Law
examines the issue of foreign investor misconduct in modern international investment law, focusing on the approach that international investment law as it currently operates has developed towards foreign investor misconduct. The term ‘misconduct’ is not a legal notion, but is used to describe a certain phenomenon, namely, a group/class of actions. This term is convenient since it makes it possible to introduce and describe the phenomenon as such, without a division into concrete types of conduct, like ‘abuse of process’, ‘violation of national law’, ‘corruption’, ‘investment contrary to international norms and standards’, etc.
Focusing telescopes in nuclear astrophysics
This volume is the first of its kind on focusing gamma-ray telescopes. Forty-eight refereed papers provide a comprehensive overview of the scientific potential and technical challenges of this nascent tool for nuclear astrophysics. The book features articles dealing with pivotal technologies such as grazing incident mirrors, multilayer coatings, Laue- and Fresnel-lenses - and even an optic using the curvature of space-time. The volume also presents an overview of detectors matching the ambitious objectives of gamma ray optics, and facilities for operating such systems on the ground and in space. The extraordinary scientific potential of focusing gamma-ray telescopes for the study of the most powerful sources and the most violent events in the Universe is emphasized in a series of introductory articles.
Financial market imperfections and corporate decisions : Lessons from the transition process in Hungary
The book presents the results of an empirical investigation of the behaviour of Hungarian firms during the transition process focusing in particular on the role of financial market imperfections for corporate capital structure and investment decisions. The results suggest that financial market reforms have succeeded, albeit partially, in hardening firms's budget constraints and improving the efficiency of the credit allocation process. In particular, following the introduction of the banking sector reform and of the new bankruptcy law, budget constraints became more binding for small private firms, while informational costs became less relevant for foreign-owned firms.
Financial accounting for decision makers ; 10th ed.
Financial Accounting for Decision Makers, 10th edition is an accessible introduction to the subject, focusing on the ways in which financial statements and information improve the quality of decision-making.
Feminist IR in Europe : Knowledge production in academic institutions
The aim of this book is to take stock of, critically engage, and celebrate feminist IR scholarship produced in Europe. Organized thematically, the volume highlights a wealth of excellent scholarship, while also focusing on the politics of location and the international political economy of feminist knowledge production.
Fatty acids
Fatty acid metabolism, including the de novo synthesis, uptake, oxidation, and derivation of fatty acids, plays several important roles at cellular and organ levels. Recent studies have identified characteristic changes in fatty acid metabolism in idiopathic pulmonary fibrosis (IPF) lungs, which implicates its dysregulation in the pathogenesis of this disorder. Here, we review the evidence for how fatty acid metabolism contributes to the development of pulmonary fibrosis, focusing on the profibrotic processes associated with specific types of lung cells, including epithelial cells, macrophages, and fibroblasts. We also summarize the potential therapeutics that target this metabolic pathway in treating IPF.
Extreme Financial Risks : From Dependence to Risk Management
Portfolio analysis and optimization, together with the associated risk assessment and management, require knowledge of the likely distributions of returns at different time scales and insights into the nature and properties of dependences between the different assets. This book offers an original and thorough treatment of these two domains, focusing mainly on the concepts and tools that remain valid for large and extreme price moves. Strong emphasis is placed on the theory of copulas and their empirical testing and calibration, because they offer intrinsic and complete measures of dependences.
Extracting Accountability : Engineers and Corporate Social Responsibility
The growing movement toward corporate social responsibility (CSR) urges corporations to promote the well-being of people and the planet rather than the sole pursuit of profit. In Extracting Accountability, Jessica Smith investigates how the public accountability of corporations emerges from the everyday practices of the engineers who work for them. Focusing on engineers who view social responsibility as central to their profession, she finds the corporate context of their work prompts them to attempt to reconcile competing domains of accountability—to formal guidelines, standards, and policies; to professional ideals; to the public; and to themselves.
Event Structure and the Left Periphery : Studies on Hungarian
This book provides substantial new results in a novel field of research examining the syntactic and semantic consequences of event structure. The studies of this volume examine the hypothesis that event structure correlates with word order, the presence or absence of the verbal particle, the [+/- specific] feature of the internal argument, aspect, focusing, negation, and negative quantification, among others. The results reported concern the telicising vs. perfectivizing role of the verbal particle; the syntactic and semantic differences of verbs denoting a delimited change, and those denoting creation or coming into being; evidence of viewpoint aspect in a language with no morphological viewpoint marking; the aspectual role of non-thematic objects; the source of the ‘exhaustive identification’ function of structural focus; the interaction of negation and aspect etc.
European Tort Law 2007
The European Tort Law Yearbook provides a comprehensive overview of the latest developments in tort law in Europe. It contains reports on most EU Member States, as well as an overview of the developments in the field of EU law. In conclusion, a comparative summary reviews the essential aspects of all reports, which are written by scholars from the respective jurisdictions. Focusing on the year 2007, the authors critically report on important court decisions, present new legislation and provide a literature overview. In addition to the national reports, the European Tort Law 2007 Yearbook contains the opening lecture of the 7th Annual Conference on European Tort Law examining “The Development of Tort Law” as well as four essays on questions of prescription.
European Tort Law 2005
The European Tort Law Yearbook provides a comprehensive overview of the latest developments in tort law in Europe. It contains reports on the developments in most EU Member States, including the new Member States the Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Slovakia and Slovenia - as well as Norway and Switzerland. Furthermore, an overview of the developments in the field of EU law is provided. In conclusion, a comparative report reviews the essential aspects of all reports. The reports are written by scholars from the respective jurisdictions. Focusing on the year 2005, the authors critically report on important court decisions, present new legislation and provide a literature overview.
European Tort Law 2004
The European Tort Law Yearbook provides a comprehensive overview of the latest developments in tort law in Europe. It contains reports on the developments in most EU Member States, including the new Member States the Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Slovakia and Slovenia – as well as Norway and Switzerland. Furthermore, an overview of the developments in the field of EU law is provided. In conclusion, a comparative report reviews the essential aspects of all reports. The reports are written by scholars from the respective jurisdictions. Focusing on the year 2004, the authors critically report on important court decisions, present new legislation and provide a literature overview. In addition to the national reports, several essays on key topics in the field of tort law are included, most of which focus on questions of strict liability.
Euro-Par 2020 : Parallel Processing ; 26th International Conference on Parallel and Distributed Computing, Warsaw, Poland, August 24–28, 2020, Proceedings
This book constitutes the proceedings of the 26th International Conference on Parallel and Distributed Computing, Euro-Par 2020, held in Warsaw, Poland, in August 2020. The conference was held virtually due to the coronavirus pandemic. The 39 full papers presented in this volume were carefully reviewed and selected from 158 submissions. They deal with parallel and distributed computing in general, focusing on support tools and environments; performance and power modeling, prediction and evaluation; scheduling and load balancing; high performance architectures and compilers; data management, analytics and machine learning; cluster, cloud and edge computing; theory and algorithms for parallel and distributed processing; parallel and distributed programming, interfaces, and languages; multicore and manycore parallelism; parallel numerical methods and applications; and accelerator computing.
