الصفحة 5
الصفحة 5
Fatty acids
Fatty acid metabolism, including the de novo synthesis, uptake, oxidation, and derivation of fatty acids, plays several important roles at cellular and organ levels. Recent studies have identified characteristic changes in fatty acid metabolism in idiopathic pulmonary fibrosis (IPF) lungs, which implicates its dysregulation in the pathogenesis of this disorder. Here, we review the evidence for how fatty acid metabolism contributes to the development of pulmonary fibrosis, focusing on the profibrotic processes associated with specific types of lung cells, including epithelial cells, macrophages, and fibroblasts. We also summarize the potential therapeutics that target this metabolic pathway in treating IPF.
Extreme Conflict and Tropical Forests
At a time when the international community is devoting significant attention to the issue of governance as a key factor in global environmental decline, this book provides a timely insight into the relationships between extreme conflict, the international trade in forest products, and the social, economic and environmental condition of tropical forests and their human communities. Drawing on the expertise of both natural and social scientists, Extreme Conflict and Tropical Forests explores the underlying causes and the social and environmental consequences of conflict in tropical forest areas. Case studies from Africa, Asia and Latin America present a range of issues – from illicit crops and ‘conflict timber’ production, to the potential of peace parks for improving human security, social quality and biodiversity conservation.
Everglades Experiments: Lessons for Ecosystem Restoration
This work covers both the structural and functional responses of the Everglades ecosystem via experimental and gradient studies on microbial activity, algal responses, macroinvertebrate populations, macrophyte populations, and productivity in response to alterations to nutrients in soil and water, hydrologic changes, and fire. Importantly, this volume reclassifies the Everglades, provides a comparison of historic and current ecological processes, and presents a new working hydrologic paradigm, which collectively provides essential lessons for the restoration of this vast peatland complex
Euro-Par 2020 : Parallel Processing ; 26th International Conference on Parallel and Distributed Computing, Warsaw, Poland, August 24–28, 2020, Proceedings
This book constitutes the proceedings of the 26th International Conference on Parallel and Distributed Computing, Euro-Par 2020, held in Warsaw, Poland, in August 2020. The conference was held virtually due to the coronavirus pandemic. The 39 full papers presented in this volume were carefully reviewed and selected from 158 submissions. They deal with parallel and distributed computing in general, focusing on support tools and environments; performance and power modeling, prediction and evaluation; scheduling and load balancing; high performance architectures and compilers; data management, analytics and machine learning; cluster, cloud and edge computing; theory and algorithms for parallel and distributed processing; parallel and distributed programming, interfaces, and languages; multicore and manycore parallelism; parallel numerical methods and applications; and accelerator computing.
Euro-Par 2019 : Parallel Processing Workshops ; Euro-Par 2019 International Workshops, Göttingen, Germany, August 26–30, 2019, Revised Selected Papers
Euro-Par is an annual, international conference in Europe, covering all aspects of parallel and distributed processing. These range from theory to practice, from small to the largest parallel and distributed systems and infrastructures, from fundamental computational problems to full-edged applications, from architecture, compiler, language and interface design and implementation to tools, support infrastructures, and application performance aspects.
Embedded Firmware Solutions : Development Best Practices for the Internet of Things
Embedded Firmware Solutions is the perfect introduction and daily-use field guide--for the thousands of firmware designers, hardware engineers, architects, managers, and developers--to Intel’s new firmware direction (including Quark coverage), showing how to integrate Intel® Architecture designs into their plans. Featuring hands-on examples and exercises using Open Source codebases, like Coreboot and EFI Development Kit (tianocore) and Chromebook, this is the first book that combines a timely and thorough overview of firmware solutions for the rapidly evolving embedded ecosystem with in-depth coverage of requirements and optimization.
Embedded Computer Systems : Architectures, Modeling, and Simulation; 20th International Conference, SAMOS 2020, Samos, Greece, July 5–9, 2020, Proceedings
This book constitutes the refereed proceedings of the 20th International Conference on Embedded Computer Systems: Architectures, Modeling, and Simulation, SAMOS 2020, held in Samos, Greece, in July 2020.* The 16 regular papers presented were carefully reviewed and selected from 35 submissions. In addition, 9 papers from two special sessions were included, which were organized on topics of current interest: innovative architectures for security and European projects on embedded and high performance computing for health applications.
Electronic Devices and Circuit Design : Challenges and Applications in the Internet of Things
Offers a broad view of the challenges of electronic devices and circuits for IoT applications. The book presents the basic concepts and fundamentals behind new low power, high-speed efficient devices, circuits, and systems in addition to CMOS. It provides an understanding of new materials to improve device performance with smaller dimensions and lower costs. It also looks at the new methodologies to enhance system performance and provides key parameters for exploring the devices and circuit performance based on smart applications.
Economics of Land Degradation and Improvement : A Global Assessment for Sustainable Development
This volume deals with land degradation, which is occurring in almost all terrestrial biomes and agro-ecologies, in both low and high income countries and is stretching to about 30% of the total global land area. About three billion people reside in these degraded lands. However, the impact of land degradation is especially severe on livelihoods of the poor who heavily depend on natural resources. The annual global cost of land degradation due to land use and cover change (LUCC) and lower cropland and rangeland productivity is estimated to be about 300 billion USD. Sub-Saharan Africa (SSA) accounts for the largest share (22%) of the total global cost of land degradation.
Economic Loss Caused by Genetically Modified Organisms : Liability and Redress for the Adventitious Presence of GMOs in Non-GM Crops
The cultivation of genetically modified (GM) crops in the EU may lead to cases, in which traditional agricultural products contain detectable traces of GMOs. On the one hand, such admixture may result from inadequate application of segregation measures by farmers. On the other hand, as agriculture is an open process that does not allow the complete isolation of individual fields, a certain degree of admixture between neighbouring crops is unavoidable in practice. The presence of GMOs in traditional products may lead to their devaluation, which would entail an economic damage to the producer of
Earth Observation of Global Change : The Role of Satellite Remote Sensing in Monitoring the Global Environment
Global Change is increasingly considered a critical topic in environmental research. Remote sensing methods provide a relevant tool to monitor global variables, since they offer a systematic coverage of the Earth Surface, at different spatial, spectral and temporal resolutions. The data provided by Earth Observation Satellites are being operationally used for monitoring atmospheric conditions, ice sheets and glaciar movements, crop dynamism and land use changes, deforestation and desertification processes, as well as water conditions. The book includes an analysis of the leading missions in global Earth observation, and then reviews the main fields in which remote sensing methods are providing vital data for global change studies.
Drug safety evaluation : Methods and protocols
Focuses on the most recent advances in the field of drug safety evaluation. Divided into seven parts, chapters detail specific aspects related to the experimental design of preclinical studies conducted to support the safety of pediatric and combination drugs, necropsy and histopathology evaluation, mass spectrometry imaging, genetic toxicology protocols including the Pig-a mutation assay, safety pharmacology methods such as automatization of patch-clamp procedures, target safety assessment for investigative toxicology, screening assays for developmental toxicology, and methods to characterize novel translational safety biomarkers like microRNAs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting to avoid known pitfalls.
Distributed Embedded Control Systems : Improving Dependability with Coherent Design
Distributed Embedded Control Systems handles the domains encountered when designing a distributed embedded computer control system as an integrated whole. First to be discussed are some basic issues about real-time systems and their properties, specifically safety. Then, system and hardware architectures are dealt.
Distributed computing and internet technology ; 17th International Conference, ICDCIT 2021, Bhubaneswar, India, January 7–10, 2021, Proceedings
This book constitutes the proceedings of the 17th International Conference on Distributed Computing and Internet Technology, ICDCIT 2020, held in Bhubaneswar, India, in January 2021. The 13 full papers presented together with 4 short papers were carefully reviewed and selected from 99 submissions. The papers were organized in topical sections named: invited talks, cloud computing and networks, distributed algorithms, concurrency and parallelism, graph algorithms and security, social networks and machine learning, and short papers.
Digital Signal Processing with Field Programmable Gate Arrays
Field-Programmable Gate Arrays (FPGAs) are revolutionizing digital signal processing as novel FPGA families are replacing ASICs and PDSPs for front-end digital signal processing algorithms. So the efficient implementation of these algorithms is critical and is the main goal of this book. It starts with an overview of today's FPGA technology, devices, and tools for designing state-of-the-art DSP systems. A case study in the first chapter is the basis for more than 40 design examples throughout. The following chapters deal with computer arithmetic concepts, theory and the implementation of FIR and IIR filters, multirate digital signal processing systems, DFT and FFT algorithms, advanced algorithms with high future potential, and adaptive filters. Each chapter contains exercises. The VERILOG source code and a glossary are given in the appendices. This edition has a new chapter on microprocessors, new sections on special functions using MAC calls, intellectual property core design and arbitrary sampling rate converters, and over 100 new exercises.
Designing Embedded Processors : A Low Power Perspective
Designing Embedded Processors examines the many ways in which processor based systems are designed to allow low power devices. It looks at processor design methods, memory optimization, dynamic voltage scaling methods, compiler methods, and multi processor methods. Each section has an introductory chapter to give a breadth view, and have a few specialist chapters in the area to give a deeper perspective. The book provides a good starting point to engineers in the area, and to research students embarking upon the exciting area of embedded systems and architectures.
Design of Systems on a Chip : Design and Test
Design of Systems on a Chip: Design&Test is the second of two volumes addressing the design challenges associated with new generations of the semiconductor technology. The various chapters are the compilations of tutorials presented at workshops in the recent years by prominent authors from all over the world. Technology, productivity and quality are the main aspects under consideration to establish the major requirements for the design and test of upcoming systems on a chip. In particular this second book include contributions on three different, but complementary axes: core design, computer-aided design tools and test methods. A collection of chapters deal with the heterogeneity aspect of core designs, showing the diversity of parts that may share the same substrate in a state-of-the-art system on a chip.
Delivery of drugs ; Vol.2 : Expectations and realities of multifunctional drug delivery systems
Examines the formulation of micro-nanosized drug delivery systems and recaps opportunities for using physical methods to improve efficacy via mechano-, electroporation. The book highlights innovative delivery methods like PIPAC, including discussions on the regulatory aspects of complex injectables. Written by a diverse range of international researchers from industry and academia, the chapters examine specific aspects of characterization and manufacturing for pharmaceutical applications as well as regulatory and policy aspects.This book connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stakeholders.
Deepfake detection
The rise of large language models (LLMs) and the increasing sophistication of deepfake images have made detecting synthetic content a pressing challenge. Several approaches have been proposed to tackle this problem, including statistical analysis, and machine learning algorithms. In this project, A novel zero-shot approach is proposed that utilizes the power of LLMs to detect fake text. The pre-trained LLM is fine-tuned to enhance its ability to differentiate real and fake text. The approach uses the LLM to detect text by analyzing the log probabilities of the text. For detecting fake images, computer vision algorithms and neural networks are used to analyze facial features. The facial region is cropped and preprocessed and the neural network identifies patterns indicative of synthetic content.
Current Concepts in Autoimmunity and Chronic Inflammation
The ethiopathologies of autoimmune diseases are complex. A broad variety of cell types and gene products are involved. This book explores clinical and experimental evidence suggesting that the importance of an individual factor changes during the course of the disease.
