الصفحة 5
الصفحة 5
Innovative Superhard Materials and Sustainable Coatings for Advanced Manufacturing ; Proceedings of the NATO Advanced Research Workshop on Innovative Superhard Materials and Sustainable Coating, Kiev, Ukraine,12 - 15 May 2004.
Modern industry imposes ever increasing requirements upon tools and tool materials as to the provision for performance under the conditions of high cutting speeds and dynamic loads as well as under intensive thermal and chemical interactions with workpiece materials. The industry demands a higher productivity in combination with the accuracy of geometry and dimensions of workpieces and quality of working surfaces of the machined pieces. These requirements are best met by the tool superhard materials (diamond and diamond-like cubic boron nitride). Ceramics based on silicon carbide, aluminum and boron oxides as well as on titanium, silicon and aluminum nitrides offer promise as tool materials. Tungsten-containing cemented carbides are still considered as suitable tool materials. Hi- hardness and high strength composites based on the above materials fit all the requirements imposed by machining jobs when manufacturing elements of machinery, in particular those operating under the extreme conditions of high temperatures and loads.
Innovations Towards Sustainability : Conditions and Consequences
The volume contains eight articles together with comments by twenty authors and discussants on the topic of innovations and sustainability. It provides a competently written, balanced and differentiated state-of-the-art insight into the relation between innovations and sustainability from the perspective of evolutionary economics. The scope of the contributions encompasses the technological, social, organizational, and political dimensions of the topic. Each article is discussed by a competently written commentary providing a critical evaluation and relating it to the relevant literature. Particular interest lies on the issues of steering opportunities and path formation capabilities by decentralized agents, or governmental institutions from the viewpoint of evolutionary economics.
Innovations in Quantitative Risk Management ; TU München, September 2013
The KPMG Center of Excellence in Risk Management conference Risk Management Reloaded and this proceedings volume contribute to bridging the gap between academia –providing methodological advances– and practice –having a firm understanding of the economic conditions in which a given model is used. Discussed fields of application range from asset management, credit risk, and energy to risk management issues in insurance. Methodologically, dependence modeling, multiple-curve interest rate-models, and model risk are addressed. Finally, regulatory developments and possible limits of mathematical modeling are discussed.
Innovation Cell : Agile Teams to Master Disruptive Innovation
This book gives you a picture of disruptive innovation and how to master it. Special attention is given to the management task in innovation, the development of the mindset for innovation and setting up of the conditions for self organisation.
Information security and privacy ; 6th Australasian Conference, ACISP 2001, Sydney, Australia, July 11-13, 2001. Proceedings
A Few Thoughts on E-Commerce.- New CBC-MAC Forgery Attacks.- Cryptanalysis of a Public Key Cryptosystem Proposed at ACISP 2000.- Improved Cryptanalysis of the Self-Shrinking Generator.- Attacks Based on Small Factors in Various Group Structures.- On Classifying Conference Key Distribution Protocols.- Pseudorandomness of MISTY-Type Transformations and the Block Cipher KASUMI.- New Public-Key Cryptosystem Using Divisor Class Groups.- First Implementation of Cryptographic Protocols Based on Algebraic Number Fields.- Practical Key Recovery Schemes.- Non-deterministic Processors.- Personal Secure Booting.- Evaluation of Tamper-Resistant Software Deviating from Structured Programming Rules.- A Strategy for MLS Workflow.- Condition-Driven Integration of Security Services.- SKETHIC: Secure Kernel Extension against Trojan Horses with Informat ion-Carrying Codes.- Secure and Private Distribution of Online Video and Some Related Cryptographic Issues.- Private Information Retrieval Based on the Subgroup Membership Problem.
Indicator Systems for Sustainable Innovation
In the recent past, environmental innovations have led to a considerable reduction of many pollutants; however, further innovation is required to tackle remaining pollution sources. This work analyses the significance and the effects of framework conditions on innovation activities that contribute to the realisation of a sustainable development. The book links the experiences of different research projects with the aim to develop a system of indicators to evaluate sustainable effects of (environmental) innovations. A comprehensive framework for an indicator system is established that allows to include different environmental innovation fields such as process innovations in the steel production, substitution of dangerous chemicals, organisational innovations in the field of waste disposal or sustainable water management.
In Vitro Drug Release Testing of Special Dosage Forms
Covers the in vitro release testing of: lipid based oral formulations; chewable oral drug products; injectables; drug eluting stents; inhalation products; transdermal formulations; topical formulations; vaginal and rectal delivery systems and ophthalmics. The book concludes with a look at regulatory aspects. Covers both oral and non-oral dosage forms Describes current regulatory conditions for in vitro drug release testing Features contributions from well respected global experts in dissolution testing
In Search of an Integrative Vision for Technology : Interdisciplinary Studies in Information Systems
This book provides a fascinating reading experience for anyone interested in an inquiring relationship between technical progress and the quality of the human condition. It manages to keep a healthier balance between these two complex topics than is found in most publications of the genre, too often they consist either of much technology and little philosophy or the converse.... The book also manages to build accessible bridges over the gulf that tends to separate the philosophical language from the 'real' concerns of technologists."
Impulse Breakdown of Liquids
The book describes the main physical processes and phenomena in pulsed electric breakdown. The knowledge and the control of the electric breakdown of liquids is important not only for the insulation inside power systems but it is also used for the creation and information of high voltage and high current pulses. Such high-voltage micro- and nanosecond pulses find wide application in experimental physics, electro discharge technology, physics of dielectrics, radar detection and ranging, high-speed photography. The nature of charge carriers, mechanism of formation and evolution of the gas phase, and their role in charge ignition (initiation) and development are considered. In particular, the spatiotemporal laws of propagation and parameters of charge channels are described in detail and the boundery conditions of the breakdown initiation are formulated.
IMPROVE - Innovative modelling approaches for production systems to raise validatable efficiency : Intelligent methods for the factory of the future
This open access work presents selected results from the European research and innovation project IMPROVE which yielded novel data-based solutions to enhance machine reliability and efficiency in the fields of simulation and optimization, condition monitoring, alarm management, and quality prediction.
Implementing responsible research and innovation : Organisational and national conditions
we give an overview of the book and the RRI-Practice study. The book is an analysis of data collected in the RRI-Practice study. It comprises an organizational analysis and an analysis of national discourses, thus analysing conditions for the uptake of RRI in research funding and research performing organisations in the science system.
Immunogenetics of Autoimmune Disease
Utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches
Imaging Technologies and Transdermal Delivery in Skin Disorders
This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. It also places great emphasis on the critical role that interdisciplinary science occupies to achieve the requisite level of understanding of skin conditions and their management, which is essential to creating technologies that work.
Illiberal Trends and Anti-EU Politics in East Central Europe
This book provides an in-depth look into the background of rule of law problems and the open defiance of EU law in East Central European countries. Current illiberal trends and anti-EU politics have the potential to undermine mutual trust between member states and fundamentally change the EU. It is therefore crucial to understand their domestic causes, context conditions, specific processes and consequences.
Identities at Work
This edited volume on Identities at Work brings together international theory and empirical research that deals with continuity and change of identity formation processes at work under conditions of modern working processes and labour market flexibility. Modern work processes in manufacturing and service organisations increasingly rely upon responsible and competent employees who are willing and able to engage in the tasks that their job requires and in continuous learning. That employees are able to engage in taking up new forms of responsibility and master complex work situations is, on the one hand, dependent upon employees’ skills and how well they are trained. On the other hand, it requires that employees identify with what they do and commit to their work and the performance of tasks.
Ibuprofen : Pharmacology, Therapeutics and Side Effects
Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.
Ibuprofen : Discovery, development and therapeutics
Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and inflammatory conditions. It has also been widely investigated for application in a variety of painful and non-pain inflammatory states including cancer and neurodegenerative conditions, reflecting the unique and novel properties of the drug that would never have been foreseen from knowledge of the properties when it was initially discovered.
IAEA Atlas of Cardiac PET/CT : A Case-Study Approach
This book presents a wide portfolio of examples of positron emission tomography coupled with computer tomography (PET/CT) studies in various cardiac conditions in order to provide a rationale for the implementation of this technology in an array of clinical conditions. Cardiovascular diseases are a major contributor to premature morbidity and mortality worldwide. Low- and middle-income countries (LMICs) are particularly affected by cardiovascular diseases (CVDs), with more than 75% of all CVDs deaths occurring in these countries. For this reason, target 3.4 of the United Nations (UN) Sustainable Development Goals (SDGs) agenda aims at a 30% reduction in premature mortality due to non-communicable diseases (NCDs), which include CVDs, by 2030.
I disturbi della consapevolezza nelle malattie neuropsichiatriche = Disturbances of awareness in neuropsychiatric diseases
Aims to outline the set of current international knowledge on disease awareness in various neuropsychiatric conditions (hemiplegia resulting from brain damage, psychosis, dementia and mood disorders), with particular reference to anosognosia and 'insight. The comparison between different conceptualizations and the variety of clinical manifestations gives rise to a very complex picture that requires a multidimensional approach, especially as regards the diagnostic moment. To this end, the authors propose an integration of various contributions on the pathogenetic level, based on neuroanatomical evidence and supported by the most recent neuroimaging techniques. In addition, the use of a complex diagnostic battery is suggested, capable of analyzing the different aspects of the phenomenon, and distinguishing it from the psychological defensive mechanism of denial. Research in this field is also essential to promote rehabilitation and compliance with treatment, as well as the enrichment of knowledge on the processes underlying consciousness and awareness in the human being.
Hypoplastic Left Heart Syndrome
Hypoplastic Left Heart Syndrome draws together the experiences of the leading experts in the field. Through their work in all aspects of congenital cardiac care, they have become acknowledged as the world leaders in the diagnostic, medical and social needs of children born with hypoplasia of the left heart. More importantly, for the first time the book recognizes the crucial contributions made by the families of these children. Diagnostic possibilities, options for medical and surgical treatment and a history of their evolution are looked into and the book also gives an insight into the longer-term effects that treatment has on the child and its family. As well as including contributions from medical clinicians, nurses, and psychologists, for the first time a forum is provided for the parents, who have complemented the contributions from the medical and nursing experts to provide a holistic view of the lives and experiences of the children born with this condition. No other publication, currently available, offers such a comprehensive overview of the care required by a child with hypoplasia of the left heart. This book provides the ultimate reference for anyone treating children with this heart condition, particularly paediatric cardiac clinical and nursing teams, radiologists and radiographers, obstetric medical and nursing teams, psychologists, pathologists, geneticists and workers in social care.
