الصفحة 5
الصفحة 5
Neuroendocrine cells and peptidergic innervation in human and rat prostrate
Introduction The prostate causes a signi?cant number of medical problems in the adult male, and the lower urinary tract symptoms are accepted as an unavoidable consequence of male aging. Most of these symptoms are mainly due to clinical benign prostatic hyperplasia (BPH), which is the most frequent benign tumor in the male, in- pendent of race or culture. On the other hand, cancer of the prostate shows an increasing incidence, being the second leading cause of death in men, after lung cancer.
Neuroeconomia, neuromarketing e processi decisionali = Neuroeconomics, neuromarketing and decision-making processes
The book covers a sector, that of the application of modern neuroscience techniques to the fields of economics and marketing, recently born and of great interest to the public, to advertisers as well as to neuroscience scholars. The book presents, in plain language and not for experts in the field, the structure and functioning of the brain (as it is known today) during human decision-making processes. Of interest is the analysis of how the different neuronal systems within the brain can cooperate with each other in generating decisions. All this simple physiological treatment is inserted in the context of the analysis of brain activity while watching commercial clips. In the original study presented in this book, the variables involved were those related to the recall of television advertising in a sample of normal young subjects. This study is simply the first that is carried out of this type in Italy and will be intended to be a reference point for subsequent studies in the sector.
Neurocutaneous Disorders : Phakomatoses and Hamartoneoplastic Syndromes
Neurocutaneous diseases are a wide group of conditions that affect the nervous system but appear as lesions of the skin. Some of the more common entities have variable forms of expression that can confuse the diagnosis; for the rare conditions it is difficult to find descriptions in the literature. Recent insights into their cellular, biochemical and molecular genetic bases have shown the essential need for a new nosology and updated genotype-phenotype correlations. The book provides an authoritative source of knowledge about these difficult problems and bridges the gap between clinical recognition and the new molecular medicine. The editors, distinguished clinicians and geneticists, assembled an internationally renowned group of collaborators, many of them the experts who first described a particular disorder or established its present accepted definition.
Neurocutaneous disorders : A clinical, ciagnostic and therapeutic approach
Provides extensive data on the more common and many of the more rare congenital and hereditary syndromes that manifest in the nervous system and skin. Though often complex and multi-systemic, these disorders can frequently be diagnosed using a combination of simple visual inspection and sound clinical expertise. Drawing on fully referenced information from thousands of articles, the international editorial team has prepared a comprehensive overview that includes historical perspectives, clinical features, the pathogenesis, and diagnostic and therapeutic strategies. In addition, it addresses the biochemical, molecular, and genetic basis of the disorders.
Neuroblastoma
Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.
Neurobiology : Methods and protocols
Serves as a guide for students in the field of neurobiology, and be a bridge between basic science researchers, doctors, and surgeons in clinical practice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Neuroanatomy for the Neuroscientist
Neurology, more than any other system of medicine, is rooted in the firm knowledge of basic science material (i.e., the anatomy, physiology, and pathology of the nervous system). This material enables students to readily arrive at diagnoses and to apply their knowledge at solving problems in clinical situations. Neuroanatomy for the Neuroscientist gives neuroscientists the tools to teach this material at levels appropriate for students at several levels of study, including undergraduate, graduate, dental, and medical school. The text also provides an updated approach to lesion localization in neurology, utilizing the techniques of computerized axial tomography (CT scanning), magnetic resonance imaging (MRI), and magnetic resonance angiography (MRA). Multiple illustrations demonstrating the value of these techniques in clinical neurology and neuroanatomical localization has been provided.
Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders : Novel Strategies for Research and Treatment
Over the past few decades the involvement of neurosteroids in brain function and mental health has attracted much interest, not only from a neuroscience perspective, but also from clinical and therapeutic aspects. In recent years, much of the research has focused on the multifunctional position of neurosteroids in the nervous system. The areas that have been explored, in particular, are the cellular and molecular mechanisms involved in the activity of neurosteroids in the brain, the role of neurosteroids in brain development, neurodegeneration and neuroplasticity, and their pharmacological properties. The large increase in the number of publications highlights this amplified interest in neurosteroids. Over the last 7 years at least 400 papers have been published describing the putative role of neurosteroids in the modulation of basic brain function and in the etiology and treatment of psychiatric and neurological disorders.
Neuroacanthocytosis Syndromes
Neuroacanthocytosis Syndromes is the first comprehensive review of a field that has not yet received the attention it deserves. Affecting the brain as well as the circulating red cells, these multi-system disorders in the past had often been mistaken for Huntington's disease. Recent breakthroughs have now identified the molecular basis of several of these. This volume grew out of the first international scientific meeting ever devoted to neuroacanthocytosis and provides in-depth information about the state of the art. Its thirty chapters were written by the leading authorities in the field to cover the clinical as well as the basic science perspective, including not only molecular genetics but also experimental pharmacology and cell membrane biology, among others. The book vehemently poses the question of how the membrane deformation of circulating red blood cells relates to degeneration of nerve cells in the brain, the basal ganglia, in particular. It provides a wealth of data that will help to solve an intriguing puzzle and ease the suffering of those affected by one of the neuroacanthocytosis syndromes.
Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
This comprehensive volume, written by experts in the integrative fields of neuroscience, endocrinology and immunology, provides insight into the mechanisms by which neural and neuroendocrine factors influence susceptibility to infection and autoimmunity. The book focuses on multiple sclerosis as the prototypic autoimmune disease and discusses infectious diseases including anthrax, influenza virus, herpes virus and human immunodeficiency virus. The effects of stress on experimental models of multiple sclerosis and also clinical observations of stress in multiple sclerosis patients are discussed. Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity is an ideal book for researches and professionals in the fields of immunology, neuroscience, infectious disease, psychology, microbiology, virology, public health and pharmaceutical sciences.
Netter's head and neck anatomy for dentistry
A concise and highly visual guide to clinically relevant anatomy for dentistry, as well as a valuable resource for any healthcare professional interested in head and neck anatomy, Netter's Head and Neck Anatomy for Dentistry, 4th Edition, is an ideal text/atlas for class and exam preparation, as well as a quick review in professional practice.
Netter's essential histology with correlated histopathology
Concise and easy to use, it integrates gross anatomy and embryology with classic histology slides and state-of-the-art scanning electron microscopy, offering a clear, visual understanding of this complex subject. Additional histopathology images, more clinical boxes, and new histopathology content ensure that this textbook-atlas clearly presents the most indispensable histologic concepts and their clinical relevance. Helps you recognize both normal and diseased structures at the microscopic level with the aid of succinct explanatory text as well as numerous clinical boxes. Features more histopathology content and additional clinical boxes to increase your knowledge of pathophysiology and clinical relevance. Includes high-quality light and electron micrographs, including enhanced and colorized electron micrographs that show ultra-structures in 3D, side by side with classic Netter illustrations that link your knowledge of anatomy and cell biology to what is seen in the micrographs.
Nephrology Worldwide
This book presents contributions from leading international experts in the field of nephrology. Each chapter is independent and discusses nephrology in the author’s country, including the history of nephrology development, kidney disease epidemiology, clinical nephrology, dialysis practice in acute and chronic renal failure settings (hemodialysis, hemodiafiltration, peritoneal dialysis), pediatric nephrology, and kidney transplantation. In addition, the book covers topics such as the job market for nephrologists, reimbursement, nephrology education, and the number of professionals in the private and public sectors.
Neoproterozoic Geobiology and Paleobiology
The Neoproterozoic Era (1000-542 million years ago) is a geological period of dramatic climatic change and important evolutionary innovations. Repeated glaciations of unusual magnitude occurred throughout this tumultuous interval, and various eukaryotic clades independently achieved multicellularity, becoming more complex, abundant, and diverse at its termination. Animals made their first debut in the Neoproterozoic too. The intricate interaction among these geological and biological events is a centrepiece of Earth system history, and has been the focus of geobiological investigations in recent decades. The purpose of this volume is to present a sample of views and visions among some of the growing numbers of Neoproterozoic workers. The contributions represent a cross section of recent insights into the field of Neoproterozoic geobiology.
Navigational Surgery of the Facial Skeleton and Skull Base
Computer-assisted techniques in the surgery of the facial skeleton including the skull base are depicted for the very first time in this atlas of navigational surgery. Experienced surgeons as well as trainees will benefit from the detailed and well-illustrated information on the use of computer technology in clinical routine, accompanied by the experimental basis of intraoperative accuracy.The interdisciplinary approach brings together maxillofacial surgeons, plastic surgeons, ENT surgeons, and neurosurgeons. New methods of non-invasive referencing and the use of virtual models in the field of oral and cranio-maxillofacial surgery are demonstrated. Clinical cases illustrate the practical use of this new technique.
Navigation and MIS in Orthopaedic Surgery
This textbook offers new insights into the use of computer assisted surgery and minimally invasive surgery in orthopaedic surgery. A comprehensive presentation of scientific work and clinical experience is included encompassing areas of spine, trauma, sports and reconstructive surgery. We have added sections that discuss minimally invasive surgery, as we believe CAS will be an enabling technology for these more challenging approaches by providing a virtual digital "surgical exposure". We have explored areas of new endeavor that may not have current applications.
Nature-Based Solutions to Climate Change Adaptation in Urban Areas : Linkages between Science, Policy and Practice
This book is open access under a CC BY 4.0 license.This book brings together research findings and experiences from science, policy and practice to highlight and debate the importance of nature-based solutions to climate change adaptation in urban areas. Emphasis is given to the potential of nature-based approaches to create multiple-benefits for society
Nature-Based Flood Risk Management on Private Land : Disciplinary Perspectives on a Multidisciplinary Challenge
This book addresses the various disciplinary aspects of nature-based solutions in flood risk management on private land. In recent decades, water management has been moving towards nature-based solutions. These are assumed to be much more multi-purpose than traditional “grey infrastructures” and seem to be regarded as a panacea for many environmental issues. At the same time, such measures require more – and mostly privately owned – land and more diverse stakeholder involvement than traditional (grey) engineering approaches. They also present challenges related to different disciplines. Nature-based solutions for flood risk management not only require technical expertise, but also call for interdisciplinary insights from land-use planning, economics, property rights, sociology, landscape planning, ecology, hydrology, agriculture and other disciplines to address the challenges of implementing them. Ultimately, nature-based flood risk management is a multi-disciplinary endeavor.
Natural Skincare Cosmetics
Aging skin is suffering of decrease pigment-containing cells and overproduction of melanin in the skin, also changes in the connective tissue reduce the skin's strength and elasticity. Over the last 20 years, clinical and laboratory studies have identified the benefits of an array of natural ingredients for skin care. A variety of skin care products exist in today’s marketplace. They fulfill a variety of functions by either acting directly on the skin (e.g., moisturizers) or being a cosmetically elegant vehicle for the delivery of specific active ingredients (e.g., sunscreens or antipruritic or antiacne medicaments). Certain ingredients used in cosmeceuticals may be claimed to be therapeutic for common skin diseases. These ingredients are regulated as over the counter (OTC) drug monographs for acne, dermatitis/psoriasis, skin protectant, topical analgesia and sunscreens, by the Food and Drug Administration (FDA)
Natural Products Targeting Clinically Relevant Enzymes
Covers the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
