الصفحة 469
الصفحة 469
Amartya Sens Capability Approach: Theoretical Insights and Empirical Applications
Kuklys examines how Nobel Prize-winning economist Amartya Sen’s approach to welfare measurement can be put in practice for poverty and inequality measurement in affluent societies such as the UK. Sen argues that an individual’s welfare should not be measured in terms of her income, but in terms what she can actually do or be, her capabilities. In Chapters 1 and 2, Kuklys describes the capability approach from a standard welfare economic point of view and provides a comprehensive literature review of the empirical applications in this area of research. In the remaining chapters, novel econometric techniques are employed to operationalise the concepts of functionings and capability to investigate inequality and poverty in terms of capability in the UK. Kuklys finds that capability measurement is always a useful complement to traditional monetary analysis, and particularly so in the case of capability-deprived disabled individuals.
Alzheimers disease : Cellular and molecular aspects of Amyloid beta
This book contains a survey of present-day research into the biomedical fundamentals of Alzheimer’s disease (AD). It contains 20 chapters dealing with widely ranging topics, all of which have a bearing upon the understanding and treatment of AD. Starting with a broad survey of the contribution that the various microscopical techniques (light microscopy, electron microscopy, atomic force microscopy)
Alzheimers Disease : Advances in genetics, molecular and cellular biology
Alzheimer’s Disease: Advances in Genetics, Cellular and Molecular Biology provides exciting, comprehensive and up-to-date summaries of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of AD. The studies and advances described in this volume will help to accelerate the process of rational drug discovery and soon serve to extend and enhance the mental health and lifespan of our burgeoning elderly population.
Alzheimers Disease
Alzheimer’s disease (AD) is a neurodegenerative disease that robs the minds of our elderly population. Approximately one in every eight adults over the age of 65 and nearly half of those over 85 are afflicted with this disease. The aging population in developed societies will impose an ever increasing socioeconomic threat in the future. Current medicines for AD patients are mainly symptomatic treatments and a huge unmet medical need exists to slow the progression of this disease. A great deal of research has been dedicated to understanding the pathogenesis of AD from which comes many ideas for intervening with its progression. Some of these ideas have been fast-tracked to clinical trials due to the availability of medicines with proven clinical efficacies for other diseases (e.g. atorvastatin, simvastatin, rosiglitazone and clioquinol) while others represent novel chemical entities (e.g. glycogen synthase kinase-3 inhibitors).
Alzheimer : 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
Alternatives to Animal Testing : Proceedings of Asian Congress 2016
This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs.
Alternatives Considered But Not Disclosed : The Ambiguous Role of PowerPoint in Cross-Project Learning
This study investigates the role of PowerPoint in organizational communication, particularly in terms of a functional dilemma between its application for documentation as opposed to presentation purposes. The theoretical part of the analysis combines insights from both organizational communication studies (J. R. Taylor et al.) and social systems theory (N. Luhmann et al.). The empirical analysis shows that PowerPoint documents created for cross-project learning purposes contribute to an invisibilization rather than a visibilization of decision processes and their contingency.
Alternative Splicing and Disease
Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.
Alternative pseudodifferential analysis : With an application to modular forms
This volume introduces an entirely new pseudodifferential analysis on the line, the opposition of which to the usual (Weyl-type) analysis can be said to reflect that, in representation theory, between the representations from the discrete and from the (full, non-unitary) series, or that between modular forms of the holomorphic and substitute for the usual Moyal-type brackets. This pseudodifferential analysis relies on the one-dimensional case of the recently introduced anaplectic representation and analysis, a competitor of the metaplectic representation and usual analysis.
Alternative Education : Global Perspectives Relevant to the Asia-Pacific Region
Alternative streams of education have been and remain an important but difficult theme for teachers, parents, policy-makers, and scholars. By focusing on case studies of six countries (Bolivia, Thailand, Australia, USA, The Netherlands, and Denmark), and by comprehensively analysing these by means of international comparative methodologies, the author approaches the nuts and bolts issues of alternative and mainstream education systems. The case studies include Charter Schools in the USA and Waldorf Schools in Australia. The study presents not only an insightful analysis of alternative forms of education with regard to actual issues in societies and also legal and administrative features of education. It provides insights into the kind of school development that could be appropriate in the 21st century and the types of educational communities we should seek to create in the age of globalisation.
Alternative breast imaging : Four model-based approaches
Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible. Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS).
Altering nature ; Vol.2 : Religion, Biotechnology, and Public Policy
The two volumes of Altering Nature consider the complex ways that concepts of 'nature' and 'the natural' are understood and the relevance of those understandings to discussions of biotechnology.Volume Two, Religion, Biotechnology, and Public Policy, reviews recent religious and ethical analyses of four specific areas of biotechnology: assisted reproduction, genetic therapy and enhancement, human-machine incorporation, and biodiversity. It identifies and explores the richer normative themes that inform particular debates and suggests ways that policy choices in biotechnology may be illuminated by devoting greater attention to religious perspectives.
Altering nature ; Vol.1 : Concepts of ‘Nature’ and ‘The Natural’ in Biotechnology Debates
Volume One, Concepts of 'Nature' and 'The Natural' in Biotechnology Debates, offers nuanced accounts of the ways that nature is invoked and interpreted, both descriptively and prescriptively, by different disciplines, including perspectives from spirituality and religion, philosophy, science and medicine, law and economics, and aesthetics. In the context of that broad discussion.
Alpine Industrial Landscapes : Towards a New Approach for Brownfield Redevelopment in Mountain Regions
This book presents a pioneering research on brownfield redevelopment in mountain regions, and specifically in the European Alps. The origins and causes, the actual conditions as well as the future challenges and potentials of mountain brownfields are investigated from an interdisciplinary yet landscape-centered perspective. Through the reasoned combination of research-by-design methods and case-study analysis, the book explores the infrastructural relevance of these sites for the specific mountain territory, while advancing an innovative structuralist-systemic approach for their physical and functional transformation. The book includes, among others, a first transnational geo-mapping of Alpine brownfields, whose impressive outcomes in terms of site numbers and distribution can only confirm the urgency of this research.
Alpha-1 antitrypsin : Methods and protocols
Provides a collection of protocols that will allow researchers to further explore the multiple, fascinating activities of Alpha-1 Antitrypsin (AAT) isoforms in innate immunity, and gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Allosteric Regulatory Enzymes
This book provides a logical introduction to the limits for enzyme function as dictated by the factors that are limits for life. This book presents a complete description of all the mechanisms used for changing enzyme acticity. Eight enzymes are used as model systems after extensive study of their mechanisms. Wherever possible, the human form of the enzyme is used to illustrate the regulatory features.
Allocating public and private resources across generations : Riding the age waves ; Vol .2
The chapters in this volume greatly develop our understanding of the nature and measurement of transfers, their motives and mechanisms, and their macro-level dimensions, especially in the context of demographic transitions.
Allergy in Practice
This book reflects the rich personal experience of a German allergist with international training and reputation, who is active in immunology and allergy research and practice for almost 30 years. In this book, not only IgE-mediated allergic reactions are covered but all other kinds of allergies such as atopic eczema, contact dermatitis, drug eruptions, anaphylaxis and food allergies are equally represented as well as psychosomatic aspects and problems of environmental intolerances.
Allergic Diseases : Diagnosis and Treatment
In this updated third edition of the critically-acclaimed volume, expert physicians assemble user-friendly, clinically-oriented guides to aid in the day-to-day management of the allergic patient. With an emphasis on common allergic diseases and the pharmacological tools to control them, Allergic Diseases: Diagnosis and Treatment, Third Edition disseminates the practical knowledge that practitioners have accumulated through practice and teaching in the field of allergy and immunology.
Allelopathy in Sustainable Agriculture and Forestry
This book reports on the latest advances in allelopathy through the contributions of leading scientists in the field. The book addresses the history of allelopathy, the science of allelochemicals, and the application of allelopathy in agriculture and forestry. An emphasis on both methodology and application makes Allelopathy a truly practical reference for scientists, researchers and students of plant science, agriculture, forestry, terrestrial ecology and environmental science.
