الصفحة 46
الصفحة 46
CD137 Pathway : Immunology and Diseases
This comprehensive volume, written by experts in the field, covers nearly all aspects of ongoing research related to the CD137 pathway. Recent research has shown that the manipulation of CD137 pathway molecules is very promising in the treatment of cancer, viral infection, transplantation rejection and autoimmune diseases in experimental animal models. The volume includes research related to the identification and understanding of functional consequences of CD137 receptor and ligand molecules which represents a major effort in the field of immunology. CD137 Pathway: Immunology and Diseases is an ideal book for immunologists, microbiologists, cancer researchers, molecular biologists, biochemists, and pharmaceutical and biotechnology company scientists.
Categories for software engineering
This book provides a gentle, software engineering oriented introduction to category theory. Assuming only a minimum of mathematical preparation, this book explores the use of categorical constructions from the point of view of the methods and techniques that have been proposed for the engineering of complex software systems: object-oriented development, software architectures, logical and algebraic specification techniques, models of concurrency, inter alia. After two parts in which basic and more advanced categorical concepts and techniques are introduced, the book illustrates their application to the semantics of CommUnity – a language for the architectural design of interactive systems. "For computer scientists, this unique book presents Category Theory in a manner tailored to their interests and with examples to which they can relate." Ira Forman, IBM "This book applies little-known yet quite powerful formal tools from category theory to software structures: designs, architectures, patterns, and styles. Rather than focus on issues at the level of computational models and semantics, it instead applies these tools to some of the problems facing the sophisticated software architect.
Catastrophe modeling : A new approach to managing risk
Catastrophe Modeling: A New Approach to Managing Risk is the first book that systematically analyzes how catastrophe models can be used for assessing and managing risks of extreme events. It focuses on natural disaster risk, but also discusses the management of terrorism risk. A unique feature of this book is the involvement of three leading catastrophe modeling firms, AIR Worldwide, EQECAT, and Risk Management Solutions, who examine the role of catastrophe modeling in rate setting, portfolio management and risk financing. Given the uncertainties associated with terrorism the book points out the opportunities for utilizing catastrophe models to set insurance rates and to examine public-private partnerships for providing financial assistance in the event of a terrorist attack. This book is strongly recommended for individuals who must make decisions regarding the management of impacts of catastrophe risks including those in both the public and private sector.
Case-Based Approximate Reasoning
Case-based reasoning (CBR) has received a great deal of attention in recent years and has established itself as a core methodology in the field of artificial intelligence. The key idea of CBR is to tackle new problems by referring to similar problems that have already been solved in the past. More precisely, CBR proceeds from individual experiences in the form of cases. The generalization beyond these experiences typically relies on a kind of regularity assumption demanding that 'similar problems have similar solutions'. Making use of different frameworks of approximate reasoning and reasoning under uncertainty, notably probabilistic and fuzzy set-based techniques, this book develops formal models of the above inference principle, which is fundamental to CBR. The case-based approximate reasoning methods thus obtained especially emphasize the heuristic nature of case-based inference and aspects of uncertainty in CBR. This way, the book contributes to a solid foundation of CBR which is grounded on formal concepts and techniques from the aforementioned fields. Besides, it establishes interesting relationships between CBR and approximate reasoning, which not only cast new light on existing methods but also enhance the development of novel approaches and hybrid systems.
Care-Related Quality of Life in Old Age : Concepts, Models and Empirical Findings
Care-Related Quality of Life in Old Age explains the theory behind Care Keys, its methodology, empirical findings, and practical considerations in promoting effective, efficient elder care aimed at social and emotional well-being and including disabled and cognitively impaired patients.
Carbonate Reservoir Characterization : An Integrated Approach
One principal need in petroleum recovery from carbonate reservoirs is the description of the three-dimensional distribution of petrophysical properties in order to improve performance predictions by means of fluid-flow computer simulations. The book focuses on a rock based approach for the integration of geological, petrophysical, and geostatistical methods to construct a reservoir model suitable to input into flow simulation programs. This second edition includes a new chapter on model construction and new examples of limestone, dolostone, and touching-vug reservoir models as well as improved chapters on basic petrophysical properties, rock-fabric/petrophysical relationships, calibration of wireline logs, and sequence stratigraphy.
Capillary Forces in Microassembly : Modeling, Simulation, Experiments, and Case Study
Capillary Forces in Microassembly discusses the use of capillary forces as a gripping principle in microscale assembly. Clearly written and well-organized, this text brings together physical concepts at the microscale with practical applications in micromanipulation. Throughout this work, the reader will find a review of the existing gripping principles, elements to model capillary forces as well as descriptions of the simulation and experimental test bench developed to study the design parameters. Using well-known concepts from surface science (such as surface tension, capillary effects, wettability, and contact angles) as inputs to mechanical models, the amount of effort required to handle micro-components is predicted. These developments are then applied in a case study concerning the pick and place of balls in a watch ball bearing.
Cancer Prevention
This volume contains the main proceedings of the fourth international conference on "Cancer Prevention 2006," which was held during February 16–18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels: genetic/biologic predisposition and definition of high-risk groups; preclinical models and tumor prevention; prospects of surrogate endpoints and biomarkers; progress in imaging and detection of neoplastic precursor lesions.
Calcolo stocastico per la finanza = Stochastic Calculation for Finance
Offers an introduction to the mathematical, probabilistic and numerical methods that are the basis of the models for the valuation of derivative instruments, such as options and futures, dealt with in modern financial markets. The book is aimed at readers with scientific training, wishing to develop skills in the field of stochastic calculus applied to finance.
Business process management ; Vol. 4102 : 4th International Conference, BPM 2006, Vienna, Austria, September 5-7, 2006, Proceedings
This book constitutes the refereed proceedings of the 4th International Conference on Business Process Management, BPM 2006. The book presents 20 revised full papers, 5 industrial papers, and 15 short papers together with an invited paper and the abstract of an invited talk. The papers are organized in topical sections on monitoring and mining, service composition, process models and languages, dynamic process management, Web service composition, and applied business process management.
Business Models and Corporate Reporting : Defining the Platform to Illustrate Value Creation
This book discusses the role of business models in corporate reporting. It illustrates the evolution of non-financial reporting, the importance of business model reporting, and the main conceptualisations of business models. It also offers a methodological contribution to the assessment of business model reporting. Finally, it discusses the main implication of business model reporting for different categories of subjects and some challenges related to this kind of disclosure
Business modeling and software design ; 10th International Symposium, BMSD 2020, Berlin, Germany, July 6-8, 2020, Proceedings
This book constitutes the refereed proceedings of the 10th International Symposium on Business Modeling and Software Design, BMSD 2020, which took place in Berlin, Germany, in July 2020. BMSD is a leading international forum that brings together researchers and practitioners interested in business modeling and its relation to software design. Particular areas of interest are: Business Processes and Enterprise Engineering; Business Models and Requirements; Business Models and Services; Business Models and Software; Information Systems Architectures and Paradigms; Data Aspects in Business Modeling and Software Development; Blockchain-Based Business Models and Information Systems; IoT and Implications for Enterprise Information Systems.
Business cycle dynamics : Models and tools
Business cycle theory has been one of the fastest growing fields in modern nonlinear economic dynamics. The book is centered around models of multiplier-accelerator type, emerging from Samuelson's seminal work, later developed into nonlinear formats by Hicks and Goodwin. These models left open ends, as the tools then available did not permit more systematic analysis.
Building intuition : Insights from basic operations management models and principles
"‘This user-friendly book will help the reader to develop insights with respect to a number of models that are important in the study and practice of operations management’. … all the chapters are extremely well written and a pleasure to read. … This would be a good book to use as a text in any operations management course, and in particular for operations management courses which are part of a ‘liberal studies’ program. It would also be good book for managers … ." (R Bharath, Journal of the Operational Research society, Vol. 60 (7), 2009)
Building a Data Warehouse : With Examples in SQL Server
The book is organized as follows. In the beginning of this book (chapters 1 through 6), you learn how to build a data warehouse, for example, defining the architecture, understanding the methodology, gathering the requirements, designing the data models, and creating the databases. Then in chapters 7 through 10, you learn how to populate the data warehouse, for example, extracting from source systems, loading the data stores, maintaining data quality, and utilizing the metadata. After you populate the data warehouse, in chapters 11 through 15, you explore how to present data to users using reports and multidimensional databases and how to use the data in the data warehouse for business intelligence, customer relationship management, and other purposes. Chapters 16 and 17 wrap up the book: After you have built your data warehouse, before it can be released to production, you need to test it thoroughly. After your application is in production, you need to understand how to administer data warehouse operation.
Browning Agents and Active Particles : Collective Dynamics in the Natural and Social Sciences
Lays out a vision for a coherent framework for understanding complex systems'' (from the foreword by J. Doyne Farmer). By developing the genuine idea of Brownian agents, the author combines concepts from informatics, such as multiagent systems, with approaches of statistical many-particle physics. This way, an efficient method for computer simulations of complex systems is developed which is also accessible to analytical investigations and quantitative predictions. The book demonstrates that Brownian agent models can be successfully applied in many different contexts, ranging from physicochemical pattern formation, to active motion and swarming in biological systems, to self-assembling of networks, evolutionary optimization, urban growth, economic agglomeration and even social systems.
Brain-inspired computing ; 4th International Workshop, BrainComp 2019, Cetraro, Italy, July 15–19, 2019, Revised Selected Papers
The 11 papers presented in this volume were carefully reviewed and selected for inclusion in this book. They deal with research on brain atlasing, multi-scale models and simulation, HPC and data infra-structures for neuroscience as well as artificial and natural neural architectures.
Brain, vision, and artificial intelligence ; 1st International Symposium, BVAI 2005, Naples, Italy, October 19-21, 2005, Proceedings
This book constitutes the refereed proceedings of the First International Symposium on Brain, Vision and Artificial Intelligence, BVAI 2005, held in Naples, Italy in October 2005. The 48 revised papers presented together with 6 invited lectures were carefully reviewed and selected from more than 80 submissions for inclusion in the book. The papers are addressed to the following main topics and sub-topics: brain basics - neuroanatomy and physiology, development, plasticity and learning, synaptic, neuronic and neural network modelling; natural vision - visual neurosciences, mechanisms and model systems, visual perception, visual cognition; artificial vision - shape perception, shape analysis and recognition, shape understanding; artificial inteligence - hybrid intelligent systems, agents, and cognitive models.
Brain Dynamics : Synchronization and Activity Patterns in Pulse-Coupled Neural Nets with Delays and Noise
This book addresses a large variety of models in mathematical and computational neuroscience.He devotes the main part to the synchronization problem. He presents neural net models more realistic than the conventional ones by taking into account the detailed dynamics of axons, synapses and dendrites, allowing rather arbitrary couplings between neurons. He gives a complete stabile analysis that goes significantly beyond what has been known so far. He also derives pulse-averaged equations including those of the Wilson--Cowan and the Jirsa-Haken-Nunez types and discusses the formation of spatio-temporal neuronal activity pattems. An analysis of phase locking via sinusoidal couplings leading to various kinds of movement coordination is included.
Brain dynamics : An introduction to models and simualtions
Brain Dynamics serves to introduce graduate students and nonspecialists from various backgrounds to the field of mathematical and computational neurosciences. Some of the advanced chapters will also be of interest to the specialists. The book approaches the subject through pulse-coupled neural networks, with at their core the lighthouse and integrate-and-fire models, which allow for the highly flexible modelling of realistic synaptic activity, synchronization and spatio-temporal pattern formation. Topics also include pulse-averaged equations and their application to movement coordination. The book closes with a short analysis of models versus the real neurophysiological system.
