Approaches to the purification, analysis and characterization of antibody-based therapeutics
Provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book.
Approaches to Metaphysics
Today, when systematic philosophy - and reason itself - are challenged both outside of and within philosophy, is it still possible to do metaphysics? This volume provides a broad perspective on contemporary approaches to the nature and the fundamental questions of metaphysics. Drawing on scholars from continental Europe, Asia, Canada, the United States, and Great Britain, and representing a variety of philosophical cultures and traditions, this volume surveys and extends work in metaphysics and its implications for broader philosophical concerns (e.g., in ethics and social philosophy, in mathematics and logic, and in epistemology). It also addresses such questions as the role of history and historicity in undertaking metaphysics, the nature of metaphysics, the priority of metaphysics over epistemology, and the challenges of empiricism and postmodernism.
Approaches to Fundamental Physics : An Assessment of Current Theoretical Ideas
This book presents contributions on particle theory, quantum field theory, general relativity, quantum gravity, string theory and cosmology. These represent the outcome of numerous discussions, taking place among the authors over a period of several years, about the research landscape of present-day fundamental theoretical physics. Indeed, the resultant book documents their attempt, out of their respective and highly specialized scientific positions, to find a way of communicating about methods, achievements and promises of the different approaches which shape the development of this field. It is therefore also an attempt to elucidate the connections between these approaches, and present them not as disjoint ventures but rather as facets of a common quest for understanding. Readers interested in fundamental approaches of theoretical physics will find this book highly stimulating and enlightening.
Apprehension and Argument : Ancient Theories of Starting Points for Knowledge
This book offers the first synoptic study of how the primary elements in knowledge structures were analysed in antiquity from Plato to late ancient commentaries, the main emphasis being on the Platonic-Aristotelian tradition. It argues that, in the Platonic-Aristotelian tradition, the question of starting points was treated from two distinct points of view: from the first perspective, as a question of how we acquire basic knowledge; and from the second perspective, as a question of the premises we may immediately accept in the line of argumentation. It was assumed that we acquire some general truths rather naturally and that these function as starting points for inquiry. In the Hellenistic period, an alternative approach was endorsed: the very possibility of knowledge became a central issue when sceptics began demanding that true claims should always be distinguishable from false ones.
Applying the Kaizen in Africa : A New Avenue for Industrial Development
At present, how to develop industries is a burning issue in Africa, where population growth remains high and economic development has thus far failed to provide sufficient jobs for many, especially young people and women. The creation of productive jobs through industrial development ought to be a central issue in steering economic activity across the continent.The authors of this book, consisting of two development economists and five practitioners, argue that the adoption of Kaizen management practices, which originated in Japan and have become widely used by manufacturers in advanced and emerging economies, is decisively the most effective first step for industrial development in Africa.This open access book discusses what Kaizen management is, why it is applicable to Africa, and why it can provide Africa with a springboard for sustainable economic growth and employment generation.
Applying reflective equilibrium : Towards the justification of a precautionary principle
This book provides the first explicit case study for an application of the method of reflective equilibrium (RE), using it to develop and defend a precautionary principle. It thereby makes an important and original contribution to questions of philosophical method and methodology. The book shows step-by-step how RE is applied, and develops a methodological framework which will be useful for everyone who wishes to use reflective equilibrium. With respect to precautionary principles, the book demonstrates how a rights-based precautionary principle can be constructed and defended.
Applying fuzzy mathematics to formal models in comparative politics
This book explores the intersection of fuzzy mathematics and the spatial modeling of preferences in political science. This book develops single- and multidimensional models of fuzzy preference landscapes and characterizes the surprisingly high levels of stability that emerge from interactions between players operating.
Applied Stratigraphy
This book aims to incorporate major aspects and essential elements underpinning the modern applications and perspectives of stratigraphy. It focuses on traditional and innovative techniques and how these can be utilized in reconstructing the geological history of sedimentary basins and in solving manifold geological problems and phenomena. Each chapter summarizes contributions by leading researchers in the field. It is hoped that this book will provide the reader with key insights into all these aspects and applications.
Applied Stochastic Processes
Applied Stochastic Processes uses a distinctly applied framework to present the most important topics in the field of stochastic processes.
Applied Stochastic Control of Jump Diffusions
The main purpose of the book is to give a rigorous, yet mostly nontechnical, introduction to the most important and useful solution methods of various types of stochastic control problems for jump diffusions and its applications.
Applied Stochastic Control of Jump Diffusions
The main purpose of the book is to give a rigorous, yet mostly nontechnical, introduction to the most important and useful solution methods of various types of stochastic control problems for jump diffusionsThe types of control problems covered include classical stochastic control, optimal stopping, impulse control and singular control. Both the dynamic programming method and the maximum principle method are discussed, as well as the relation between them. Corresponding verification theorems involving the Hamilton-Jacobi Bellman equation and/or (quasi-)variational inequalities are formulated. There are also chapters on the viscosity solution formulation and numerical methods.The text emphasises applications, mostly to finance. All the main results are illustrated by examples and exercises appear at the end of each chapter with complete solutions. This will help the reader understand the theory and see how to apply it.The book assumes some basic knowledge of stochastic analysis, measure theory and partial differential equations.
Applied Statistics Using SPSS, STATISTICA, MATLAB and R
The book provides a comprehensive coverage of the main statistical analysis topics important for practical applications such as data description, statistical inference, classification and regression, factor analysis, survival data and directional statistics.
Applied Spatial Data Analysis with R
Applied Spatial Data Analysis with R is divided into two basic parts, the first presenting R packages, functions, classes and methods for handling spatial data, The second part showcases more specialised kinds of spatial data analysis, including spatial point pattern analysis, interpolation and geostatistics, areal data analysis and disease mapping.
Applied soft computing technologies : The challenge of complexity
This volume presents the proceedings of the 9th Online World Conference on Soft Computing in Industrial Applications (WSC9), September 20th - October 08th, 2004, held on the World Wide Web. It contains plenary lectures, original papers and tutorials presented during the conference. The book brings together outstanding research and developments in the field of soft computing (evolutionary computation, fuzzy logic, neural networks, and their fusion) and its applications in science and technology.
Applied Semi-Markov Processes
The book presents homogeneous and non-homogeneous semi-Markov processes, as well as Markov and semi-Markov rewards processes. These concepts are fundamental for many applications, but they are not as thoroughly presented in other books on the subject as they are here.This book is intended for graduate students and researchers in mathematics, operations research and engineering; it might also appeal to actuaries and financial managers, and anyone interested in its applications for banks, mechanical industries for reliability aspects, and insurance companies.
Applied scanning probe methodsVII : Biomimetics and industrial applications
The present volumes cover three main areas: novel probes and techniques (Vol. V), charactarization (Vol. VI), and biomimetics and industrial applications (Vol. VII). Volume V includes an overview of probe and sensor technologies including integrated cantilever concepts, electrostatic microscanners, low-noise methods and improved dynamic force microscopy techniques, high-resonance dynamic force - croscopy and the torsional resonance method, modelling of tip cantilever systems, scanning probe methods, approaches for elasticity and adhesion measurements on the nanometer scale as well as optical applications of scanning probe techniques based on near?eld Raman spectroscopy and imaging.
Applied scanning probe methods X : Biomimetics and industrial applications
The success of the Springer Series Applied Scanning Probe Methods I–VII and the rapidly expanding activities in scanning probe development and applications worldwide made it a natural step to collect further speci c results in the elds of development of scanning probe microscopy techniques (Vol. VIII), characterization (Vol. IX), and biomimetics and industrial applications (Vol. X). These three volumes complement the previous set of volumes under the subject topics and give insight into the recent work of leading specialists in their respective elds. Following the tradition of the series, the chapters are arranged around techniques, characterization and biomimetics and industrial applications. Volume VIII focuses on novel scanning probe techniques and the understanding of tip/sample interactions. Topics include near eld imaging, advanced AFM, specialized scanning probe methods in life sciences including new self sensing cantilever systems, combinations of AFM sensors and scanning electron and ion microscopes, calibration methods, frequency modulation AFM for application in liquids, Kelvin probe force microscopy, scanning capacitance microscopy, and the measurement of electrical transport properties at the nanometer scale.
Applied scanning probe methods VIII : Scanning probe microscopy techniques
The success of the Springer Series Applied Scanning Probe Methods I–VII and the rapidly expanding activities in scanning probe development and applications worldwide made it a natural step to collect further speci c results in the elds of development of scanning probe microscopy techniques (Vol. VIII), characterization (Vol. IX), and biomimetics and industrial applications (Vol. X). These three volumes complement the previous set of volumes under the subject topics and give insight into the recent work of leading specialists in their respective elds. Following the tradition of the series, the chapters are arranged around techniques, characterization and biomimetics and industrial applications. Volume VIII focuses on novel scanning probe techniques and the understanding of tip/sample interactions. Topics include near eld imaging, advanced AFM, s- cializedscanningprobemethodsinlifesciencesincludingnewselfsensingcantilever systems, combinations of AFM sensors and scanning electron and ion microscopes, calibration methods, frequency modulation AFM for application in liquids, Kelvin probe force microscopy, scanning capacitance microscopy, and the measurement of electrical transport properties at the nanometer scale.
Applied scanning probe methods VI : Characterization
The scanning probe microscopy feld has been rapidly expanding. It is a demanding task to collect a timely overview of this feld with an emphasis on technical dev- opments and industrial applications. It became evident while editing Vols. I–IV that a large number of technical and applicational aspects are present and rapidly - veloping worldwide. Considering the success of Vols. I–IV and the fact that further colleagues from leading laboratories were ready to contribute their latest achie- ments, we decided to expand the series with articles touching felds not covered in the previous volumes. The response and support of our colleagues were excellent, making it possible to edit another three volumes of the series
Applied scanning probe methods V : Scanning probe microscopy techniques
The scanning probe microscopy ?eld has been rapidly expanding. It is a demanding task to collect a timely overview of this ?eld with an emphasis on technical dev- opments and industrial applications. It became evident while editing Vols. I–IV that a large number of technical and applicational aspects are present and rapidly - veloping worldwide. Considering the success of Vols. I–IV and the fact that further colleagues from leading laboratories were ready to contribute their latest achie- ments, we decided to expand the series with articles touching ?elds not covered in the previous volumes. The response and support of our colleagues were excellent, making it possible to edit another three volumes of the series.



















