الصفحة 45
الصفحة 45
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Clinical trial registries : A practical guide for sponsors and researchers of medicinal products

A necessary addition to the library of all researchers who plan to publish their results in top-tier, peer-reviewed journals. ICMJE editors and other journal editors require registration of clinical trial information on publicly available Web sites before enrollment of study subjects and some countries and regions also require this information, as well as timely publication of study results. Not only does this book discuss the genesis of these requirements, it also provides practical information for researchers and sponsors on how to establish a workflow for a clinical registry project, how to file to a registry, and how to post results. More than 25 current Web addresses for registries are provided as well as a comprehensive annotated bibliography of papers on the topic of clinical trial registries. This book is a valuable source of information for all sponsors of medicinal products.

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Clinical Research Methods for Surgeons

The text addresses the clinical research questions facing 21st century surgeons, and provides clear direction on how to incorporate sophisticated research techniques into practice. In addition to the surgical generalist, this practical volume is specifically oriented to surgeons who treat unique diseases, yet have no single resource to facilitate clinical research in these specific areas. This comprehensive and easy-to-use guide encompasses the entire process of clinical study design, application, and assessment. Part One is aimed at the young surgeon about to engage in new studies, and gives a general overview of the infrastructure of clinical research. Parts Two and Three are geared towards experienced investigators interested in pursuing clinical research and surgeons reviewing the literature for practical application. Part Two focuses on study design and related statistical issues, while Part Three is concerned with measuring and assessing the outcome of clinical studies. Part Four presents topics of interest to the active investigator, such as quality of care and cost-effectiveness analyses. Clinical Research Methods for Surgeons is relevant to both beginning investigators and established researchers, and addresses the unique concerns of surgical diseases and acknowledges that they require special approaches to deal with clinical questions.

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Clinical psychology and heart disease

The publication offers a thorough and up-to-date review of scientific research supporting evidence of the relationship between cardiac disease and psychological condition, and offers practical suggestions for developing a clinical practice, and directions for future research in the new field of "cardiac psychology". Every chapter is authored by world-renowned researchers in the field.

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Clinical Pharmacology of Sleep

This volume covers the clinical and pharmacological treatment of several important sleep disorders such as insomnia, sleep apnea, narcolepsy, restless legs syndrome, and periodic limb movement syndrome. It further addresses the use of sleep medications in children, adolescents, and in the elderly. It offers a comprehensive overview of the currently available hypnotic medications and covers aspects of chronopharmacology and its implications for the pharmacology of sleep. It also reviews the basic science of sleep and sleep disorders, and thus the potential development of new pharmacological approaches. The book will be useful for physicians, psychopharmacologists, psychiatrists, sleep disorder specialists and other healthcare professionals such as nurses, social workers and graduate medical students.

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Clinical PET and PET

A practical manual covering the full spectrum of PET and PET/CT imaging, now in common clinical practice, this book includes images of normal variants, artifacts, and pathologic conditions. Indications for and the relative clinical value of PET in the armamentarium of diagnostic medical imaging are reviewed. The information in the book is organized to be brief, concise, easy-to-understand and readily accessed.

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Mathematical Methods in Time Series Analysis and Digital Image Processing

The aim of this volume is to bring together research directions in theoretical signal and imaging processing developed rather independently in electrical engineering, theoretical physics, mathematics and the computer sciences. In particular, mathematically justified algorithms and methods, the mathematical analysis of these algorithms, and methods as well as the investigation of connections between methods from time series analysis and image processing are reviewed. An interdisciplinary comparison of these methods, drawing upon common sets of test problems from medicine and geophysical/enviromental sciences, is also addressed.

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Mathematical Methods in Engineering

This book contains some of the contributions that have been carefully selected and peer-reviewed, which were presented at the International Symposium MME06 Mathematical Methods in Engineering, held in Cankaya University, Ankara, April 2006. The Symposium provided a setting for discussing recent developments in Fractional Mathematics, Neutrices and Generalized Functions, Boundary Value Problems, Applications of Wavelets, Dynamical Systems and Control Theory.

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Mathematical Knowledge Management ; Vol. 4108 ; 5th International Conference, MKM 2006, Wokingham, UK, August 11-12, 2006, Proceedings

This book constitutes the refereed proceedings of the 5th International Conference on Mathematical Knowledge Management, MKM 2006, held in Wokingham, UK in August 2006 as official satellite event of the International Congress of Mathematicians, ICM 2006. The 22 revised full papers presented were carefully selected during two rounds of reviewing and improvement. The papers in this volume cover the whole area of mathematical knowledge management in the intersection of mathematics, computer science, library science, and scientific publishing. The papers are organized in topical sections on proof representations, proof processing, knowledge extraction, knowledge representation, as well as systems and tools.

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Mathematical Foundations of Computer Science 2008 ; 33rd International Symposium, MFCS 2008, Toru´n, Poland, August 25-29, 2008. Proceedings

Constitutes the refereed proceedings of the 33rd International Symposium on Mathematical Foundations of Computer Science, MFCS 2008, held in Torun, Poland, in August 2008.The 45 revised full papers presented together with 5 invited lectures were carefully reviewed and selected from 119 submissions. All current aspects in theoretical computer science and its mathematical foundations are addressed, ranging from algorithmic game theory, algorithms and data structures, artificial intelligence, automata and formal languages, bioinformatics, complexity, concurrency and petrinets, cryptography and security, logic and formal specifications, models of computations, parallel and distributed computing, semantics and verification.

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Mathematical foundations of computer science 2006 ; 31st International Symposium, MFCS 2006, Stará Lesná, Slovakia, August 28-September 1, 2006, Proceedings

This book constitutes the refereed proceedings of the 31st International Symposium on Mathematical Foundations of Computer Science, MFCS 2006, held in Stará Lesná, Slovakia in August/September 2006. The 62 revised full papers presented together with the full papers or abstracts of 7 invited talks were carefully reviewed and selected from 174 submissions. All current aspects in theoretical computer science and its mathematical foundations are addressed, ranging from algorithms and data structures, to complexity, automata, semantics, logic, formal specifications, models of computation, concurrency theory, computational geometry, parallel and distributed computing, networks, bioinformatics, quantum computing, cryptography, knowledge-based systems, and artificial intelligence.

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Materials, Chemicals and Methods for Dental Applications

Focuses on the materials used for dental applications looking at the fundamental issues and the developments that have taken place the past decade. While it provides a broad overview of dental materials, the chemicals that are used for the preparation and fabrication of dental materials are explained as well. Also, the desired properties of these materials are discussed and the relevance of the chemical, physical, and mechanical properties is elucidated. Methods for the characterization and classification, as well as clinical studies are reviewed here. In particular, materials for dental crowns, implants, toothpaste compositions, mouth rinses, as well as materials for toothbrushes and dental floss are discussed. For example, in toothpaste compositions, several classes of materials an chemcials are incorporated, such as abrasives, detergents, humectants, thickeners, sweeteners, coloring agents, bad breath reduction agents, flavoring agents, tartar control agents, and others. These chemicals, together with their structures, are detailed in the text.

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Materials science for dentistry

A standard resource for undergraduate and postgraduate courses in dentistry. It provides fundamental coverage of the materials on which dentistry depends, covering the structure and chemistry that govern the behavior and performance of materials. Particular classes of materials include gypsum, polymers, acrylic, cements, waxes, ceramics and metals. Other chapters review surfaces, corrosion, mixing, casting, cutting and bonding, and mechanical testing. This updated edition, which includes substantial chapters on chemistry, has been extensively revised with new material on temporary restoration resins, hydraulic silicate cements and the practical aspects of wetting surfaces. Mindfully written to provide explanations for behavior, formulation, clinical and laboratory instructions and procedures, there is no comparable resource for researchers, students, teachers and practitioners in the field of dentistry.

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Matematica si parte! : Nozioni di base ed esercizi per il primo anno di Ingegneria = Mathematics, let's go! : Basics and exercises for the first year of Engineering

This manual has been created to allow future engineering students to successfully face their studies. Some basic concepts in mathematics are presented, generally already learned before entering the University. It has been found that not all students have a complete mastery of this set of fundamental notions: therefore this manual provides useful support, in the form of both exercises and theoretical notions. The future student will be able to choose the chapters that interest him most, in order to verify his ability to solve problems such as "Review problems", using his own reasoning skills and knowledge.

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Mastering VMware Horizon 8 : An Advanced Guide to Delivering Virtual Desktops and Virtual Apps

Learn all about designing, installing, configuring, and managing VMware Horizon, with a core focus on how to deliver virtual desktops using Horizon. This book allows you to follow the complete process for deploying VMware Horizon and covers the design, deployment, and management of solutions. You will: See the core components of VMware Horizon and their functionality / Design and install a Horizon environment / Deliver the best end-user experience / Manage the deployed solution / Use VMware reference architectures to create real-life scenario examples / Review the minimum requirements for designing a solution

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Markov Processes, Brownian Motion, and Time Symmetry

The book consists of two parts. Part I,This part introduces strong Markov processes and their potential theory. In particular,it studies Brownian motion, and shows how it generates classical potential theory.Part II, focus on the effects of time reversal, duality, and time-symmetry on potential theory. Certain theorems in Part I are re-proved in Part II under slightly weaker hypotheses. The volume is very useful for people who wish to learn Markov processes but it seems to the reviewer that it is also of great interest to specialists in this area who could derive much stimulus from it. One can be convinced that it will receive wide circulation." (Mathematical Reviews)

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Map Projections : Cartographic Information Systems

In the context of Geographical Information Systems (GIS) the book offers a timely review of map projections (sphere, ellipsoid, rotational surfaces) and geodetic datum transformations. For the needs of photogrammetry, computer vision, and remote sensing space projective mappings are reviewed.

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Many Body Structure of Strongly Interacting Systems ; Refereed and Selected Contributions from the Symposium "20 Years of Physics at the Mainz Microtron MAMI"

This carefully edited proceedings volume provides an extensive review and analysis of the work carried out over the past 20 years at the Mainz Microtron (MAMI). This research centered around the application of Quantum Chromodynamics in the strictly nonperturbative regime at hadronic scales of about 1 fm. Due to the many degrees of freedom in hadrons at this scale the leitmotiv of this research is "Many body structure of strongly interacting systems". Further, an outlook on the research with the forthcoming upgrade of MAMI is given. This volume is an authoritative source of reference for everyone interested in the field of the electro-weak probing of the structure of hadrons.

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Manual of laboratory testing methods for dental restorative materials

Delivers a comprehensive and accessible review of the materials used in restorative dentistry. The book offers readers an evidence-based application of the materials and their mechanical, physical, and optical properties. Each chapter begins with key points and includes a glossary to aid in the learning and retention of the material contained within. The book also covers the methods used to study the properties and the advantages and disadvantages of various dental restorative materials as well as why they are selected.

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Manual of Digital Earth

This book offers a summary of the development of Digital Earth over the past twenty years. By reviewing the initial vision of Digital Earth, the evolution of that vision, the relevant key technologies, and the role of Digital Earth in helping people respond to global challenges, this publication reveals how and why Digital Earth is becoming vital for acquiring, processing, analysing and mining the rapidly growing volume of global data sets about the Earth.

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Mantle Plumes : A Multidisciplinary Approach

In this book, a group of experts review these advances in plume research and present a general overview on recent plume studies.

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