الصفحة 45
الصفحة 45
Biomarkers for alzheimer’s disease drug development
Aims to build a new generation of experts with a broader understanding of key topics in the Alzheimer’s disease field. Chapters guide readers through innovative approaches to the discovery of novel biomarkers in cerebrospinal fluid, innovation in blood-based biomarkers, a comprehensive overview of magnetic resonance imaging and molecular imaging approaches and their value for developing drugs for Alzheimer’s disease, cutting-edge developments in neuropathology and their relevance for Alzheimer’s disease trials, novel genomic strategies for biomarker development, and related topics including neuropsychological testing and advanced analytical methods.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Biology and Ecology of Norway Spruce
This book presents a concise and comprehensive review of the biology, ecology, and management of Norway spruce. It integrates classic and contemporary literature (more than 2000 works cited in the text), highlighting basic research and forestry practices in central and eastern Europe. The topics include anatomy and morphology, physiology and nutrition, reproductive biology and genetics, and ecology. In addition, it examines mycorrhiza, diseases and pests as well as silviculture and wood products. In the light of increasing threats to forest health from air pollution, climate change, and insects and disease, it provides an essential information source to those concerned with the ecology, conservation, and management of the species
Biological Low-Voltage Scanning Electron Microscopy
Biological Low-Voltage Scanning Electron Microscopy is the first book to address both of these aspects of biological LVSEM. After providing a thorough description of the unique advantages and the operating constraints related to operating a scanning electron microscope at low beam voltage, the remainder of book focuses on the the best way to image all types of plant and animal cells and covers specimens that range from macromolecules to the surfaces revealed by de-embedding resin-embedded samples. Advanced specimen preparation techniques such as cryo-LVSEM, and immuno-gold-LVSEM are fully covered, as is x-ray microanalysis at low beam voltage and live-time stereo imaging. The preparative protocols provided represent the distilled essence of the experience of a group of world-renowned authors who have, for many decades, been instrumental in developing and applying new approaches to LVSEM to support their own biological research.
Bioinformatics and Computational Biology Solutions Using R and Bioconductor
Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including: Importation and preprocessing of high-throughput data from microarray, proteomic, and flow cytometry platforms / Curation and delivery of biological metadata for use in statistical modeling and interpretation. / Statistical analysis of high-throughput data, including machine learning and visualization,modeling and visualization of graphs and networks. This book is a dynamic document. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Bioinformatics : Problem Solving Paradigms
This book highlights basic paradigms of problem analysis and algorithm design in the context of core bioinformatics problems. Mathematically demanding themes are put across to the reader by properly chosen representations with the aid of lots of illustrations.
Biodiversity in Enclosed Seas and Artificial Marine Habitats ; Proceedings of the 39th European Marine Biology Symposium, held in Genoa, Italy, 21-24 July 2004
The main themes of the Symposium were biodiversity in enclosed and semi-enclosed seas and artificial habitats, and the restoration of degraded systems. These themes are highly relevant today both from a basic scientific point of view and from an applied approach. The papers dealing with the first theme represent current research and concerns about marine biodiversity in enclosed seas and will have wide appeal to all those interested in understanding and preserving the biodiversity of the seas and in particular of the Mediterranean and Black Seas. The papers in the second theme represent a synthesis of up-to-date knowledge on artificial habitats and how they can contribute to protection of coastal marine ecosystems, to enhancement of species diversity and biological resources and to restoration of degraded marine environments.
BIM for design firms : Data rich architecture at small and medium scales
Expands on Building Information Modeling, showing its applicability to a range of design-oriented projects. It emphasizes the full impact that a data modeling tool has on design processes, systems, and the high level of collaboration required across the design team. It also explains the quantitative analysis opportunities that BIM affords for sustainable design and for balancing competing design agendas, while highlighting the benefits BIM offers to designing in 3D for construction. The book concludes with a deep look at the possible future of BIM and digitally-enhanced design.
Bilinear integrable systems : From classical to quantum, continuous to discrete ; Proceedings of the NATO Advanced Research Workshop on Bilinear Integrable Systems: From Classical to Quantum, Continuous to Discrete St. Petersburg, Russia, 15-19 September 2002
Trained as a physicistin his home university Kyushu University, Professor Hirota earned his PhD in’61 at Northwestern University with Professor Siegert in the field of “QuantumStatistical mechanics”. He wrote a widely appreciated Doctoral dissertation on“Functional Integral representation of the grand partition function”. As a youngresearcher, he entered the RCA Company in Tokyo to do research on semi-conductor plasmas. Professor Hirota was led to model the Toda lattice as a non-linear networkof ladder-type LC circuits. The self-dual case led to equations very reminiscentof the Sine-Gordon equation, with much the same features (existence of onesoliton, soliton-soliton interaction, etc)
Beyond global food supply chains : Crisis, disruption, regeneration
Through a set of incisive essays, this incredibly timely book shows how much the COVID-19 pandemic has exposed both vulnerabilities and opportunities - for (racial) capitalism and its discontents alike to intervene in food supply chains. A most welcome publication! This book takes the upheaval of the global COVID-19 pandemic as a springboard from which to interrogate a larger set of structural, environmental and political fault lines running through the global food system. In a context in which disruptions to the production, distribution, and consumption of food are figured as exceptions to the smooth, just-in-time efficiencies of global supply chains, these essays reveal the global food system as one that is inherently disruptive of human lives and flourishing, and of relationships between people, places, and environments. The pandemic thus represents a particular, acute moment of disruption, offering a lens on a deeper, longer set of systemic processes, and shining new light on transformational possibilities.
Bevande analcoliche : Piacere, libertá, responsabilitá = Non-alcoholic drinks : Pleasure, freedom, responsibility
The increase in physical activity and responsible moderation in the intake of food and drinks represent the best strategy to control the phenomenon of obesity in our society.
Beginning SUSE Linux : From novice to professional
The book begins by discussing the background of Linux and open source software, then proceeds to guide you through the SUSE installation process. You'll learn how to use the basic functions, and modify the look and feel according to your tastes. This book is packed with troubleshooting tips, so even the most cautious beginner will feel right at home. Next, the book covers the daily usage tasks that are enjoyable and interesting to learn. You'll learn how to configure your system to listen to audio CDs and MP3s, burn CDs, watch movies, connect to the Internet, and reproduce common Windows tasks.
Beginning Database Design : From novice to professional
Beginning Database Design: From Novice to Professional provides short, easy-to-read explanations of how to get database design right the first time. Through the help of use cases and class diagrams modeled in the UML, youll learn how to discover and represent the details and scope of the problem in question.
Beginning CakePHP : From novice to professional
CakePHP is a leading PHP–based web app development framework. When asking a question on forums or chat rooms, many CakePHP beginners get little help from the experts. Simple questions can get a response like, “Well, just read the online manual and API.” Unfortunately, the online manual is depreciated, and who wants to absorb a programming language or framework from an API? Beginning CakePHP will do the following: Lead you from a basic setup of CakePHP to building a couple applications that will highlight CakePHP’s functionality and capabilities without delving too deeply into the PHP language, but rather what the CakePHP framework can offer the developer. Teach you to use CakePHP by incorporating advanced features into your web development projects.
Basic Notions of Algebra
Aims to present a general survey of algebra, of its basic notions and main branches.Those parts of the book devoted to the systematic treatment of notions and results of algebra make very limited demands on the reader: we presuppose only that the reader knows calculus, analytic geometry and linear algebra in the form taught in many high schools and colleges. The extent of the prerequisites required in our treatment of examples is harder to state; an acquaintance with projective space, topological spaces, differentiable and complex analytic manifolds and the basic theory of functions of a complex variable is desirable, but the reader should bear in mind that difficulties arising in the treatment of some specific example are likely to be purely local in nature, and not to affect the understanding of the rest of the book.
Basic methods and protocols on Sourdough
Details traditional and modern approaches to characterize sourdough and to monitor its features during production, propagation and use, through state-of- the art analytical tools. Chapters guide reader through procedures to prepare and propagate the mature sourdough, to analyse and monitor microbiological, biochemical and rheology features of sourdough, sensory, and nutritional attributes of baked goods. Written in the format of the Methods and Protocols in Food Science series, chapters list necessary materials and methods for readily reproducible protocols.
Basic & Clinical Pharmacology
Covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. This edition has been extensively updated to provide expanded coverage of transporters, pharmacogenomics, and new drugs Delivers the knowledge and insight needed to excel in every facet of pharmacology!. Encompasses all aspects of medical pharmacology, including botanicals and over-the-counter drugs Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters New chapter on the increasingly relevant topic of cannabis pharmacology Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information Revised full-color illustrations provide more information about drug mechanisms and effects and help clarify important concepts Trade Name/Generic Name tables are provided at end of each chapter for easy reference when writing a chart order or prescription Includes descriptions of important new drugs released through May 2019 New and updated coverage of general concepts relating to recently discovered receptors, receptor mechanisms, and drug transporters
Banking for Family Business: A New Challenge for Wealth Management
Hints of globalization have actually been around for several decades, even though they made only a modest impact; however, the availability of global capital and advances in communication technology have emp- sized the process of internationalization and the tools available to connect and integrate business activities to answer to more complex needs of c- ents. Moreover, the financial scandals and the review of mutual fund trade activity in the US by the Attorney General Elliot Spitzer have highlighted the importance to focus all efforts on renewing the confidence of prof- sional investors and their clients who have entrusted their capital to asset managers. Therefore, there is a growing need in the market to reinforce the concept of “Shared Positive Values” among the entire industry and among its stakeholders.
Baculovirus : Methods and protocols
Provides up-to-date guidance on techniques used to work with baculoviruses and insect cells. The book provides basic methods to create recombinant baculoviruses, to improve productivity, to produce a variety of products, to purify products, to quantify baculovirus stocks or to quantify product produced, and it concludes with alternative uses of either baculovirus or insect cells as tools. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacteriophage therapy: From lab to clinical practice
Details new and updated experimental approaches for isolating, formulating, and engineering bacteriophage medicinal products. Authored by leading experts and written in the highly successful Methods in Molecular Biology series format, each chapter includes introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and valuable tips for troubleshooting and avoiding known pitfalls.
Bacterial regulatory RNA : Methods and protocols
Details new and updated methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters detail discovery of ncRNAs, characterization of their structure, functions, and their interactomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
