الصفحة 41
الصفحة 41
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Pharmaceutical biotechnology : fundamentals and applications

Explains both basic science and applications of pharmaceutical biotechnology / Complete one-stop source for students and professionals / Explains both the basic science and the applications of biotechnology derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those who did not receive formal training in this field. Pharmaceutical Biotechnology: Fundamentals and Applications, Fifth Edition completely updates the previous edition, and includes additional coverage on newer approaches such as oligonucleotides, mi/siRNA, gene therapy and advanced therapeutics.

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Pharma technology

Historically the technology was a driving force behind many medical and pharmacological achievements worldwide therefore the card was determined in this project to perform it in collaboration in between two faculties ( faculty of pharmacy and Information technology faculty ), in order to combine the gained experience in both fields at least in Arab international university. The goal of the project is how to use such combination in two major inventions in order to help the pharmacologist from the beginning of his academic life in our faculty.

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Pharma technology

Embedding technology in the pharmacy can unlock the abilities of pharmacists and technicians to help care for patients, improving their job satisfaction and health outcomes for the patient. With technology, pharmacists and technicians can—and should—be full members of the patient’s care team, one of embedding technology in pharmacy examples are embedding VR into the academic medical education process, and digitalizing patient’s information into a health card. Virtual reality (VR) is a simulated experience that can be similar to or completely different from the real world. Applications of virtual reality include entertainment (particularly video games), education (such as medical or military training) and business (such as virtual meetings). Other distinct types of VR-style technology include augmented reality and mixed reality, sometimes referred to as extended reality or XR.

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PGPR : Biocontrol and Biofertilization

PGPR have gained world wide importance and acceptance for agricultural benefits. These microorganisms are the potential tools for sustainable agriculture and the trend for the future. Scientific researches involve multidisciplinary approaches to understand adaptation of PGPR to the rhizosphere, mechanisms of root colonization, effects on plant physiology and growth, biofertilization, induced systemic resistance, biocontrol of plant pathogens.

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PET-CT : A Case Based Approach

This PET-CT case-based book, which reveals how PET-CT can be applied in routine clinical scenarios. Leading authorities in the field examine a wealth of original PET-CT cases that showcase both common and uncommon cancers, and the latest PET-CT applications for neurological and cardiovascular disorders. Correlative three-dimensional cross-sectional PET and CT images highlight pathological findings. Each of the clinical applications is accompanied by a concise explanation of the patient history and interpretation of the PET-CT study. Insightful discussions and "pearls and pitfalls" are included to assist in a better understanding of pathology, diagnosis, and imaging approaches. Readers also find important coverage of pathophysiology and technical artifacts. This unique book is ideal for nuclear medicine practitioners, radiologists, and residents, as well as referring clinicians interested in learning more about how this new medical imaging technology can be applied in their patient populations.

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PET Chemistry : The Driving Force in Molecular Imaging

Molecular imaging (MI) is based on the selective and specific interaction of a molecular probe with a biological target which is visualized through nuclear, magnetic resonance, near infrared or other methods. Therefore it is the method of choice for patient selection and therapy monitoring as well as for specific e- point monitoring in modern drug development. PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry. ‘PET chemistry’ can be de?ned as the study of positron-emitting compounds regarding their synthesis, structure, composition, reactivity, nuclear properties and processes and their properties in natural and - natural environments.

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Pests of Crops in Warmer Climates and Their Control

A textbook providing basic data about the crop pests and the damage they inflict throughout the tropics and sub-tropics. Each major pest is illustrated by either a line drawing or a photograph, and sometimes the damage can also be seen. A world distribution map is provided for each species. Control measures tend to be general rather than very specific. Most of the pests are insects and mites, but some nematodes, molluscs, birds and mammals are included.

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Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy

This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled “Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. “The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis.

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Personalized medicine

The introduction of personalized medicine (PM) has been a milestone in the history of medical therapy, because it has revolutionized the previous approach of treating the disease with that of treating the patient. It is known today that diseases can occur in different genetic variants, making specific treatments of proven efficacy necessary for a given endotype. There is a growing attention towards personalized medicine. This is led by a fundamental shift from the ‘one size fits all’.. (Every year in the USA 2 million people die due to adverse drug effects, Drug efficacy is only in 60 % of the population - Other 40 % have poor drug effects or no effect at all ) paradigm for treatment of patients with conditions or predisposition to diseases, to one that embraces novel approaches, such as tailored target therapies, to achieve the best possible outcomes.

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Peroxiredoxin Systems : Structures and Functions

In the introductory Chapter 1 we provide a short historical survey of the subject, based upon the early structural and enzymic studies on peroxiredoxins, and then lead into some of our current personal interests, such as the likely continuing contribution of transmission electron microscopy (TEM) for the study of high molecular mass peroxiredoxin complexes and the association of peroxiredoxins with other proteins, and the targeting of drugs against microbial peroxiredoxins, as future therapeutic approaches.

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Peritoneal Carcinomatosis : a Multidisciplinary Approach

This book will be of interest for medical, surgical and gynecological oncologists faced with the complexities of decision making in patients suffering from PC, as well as for basic and translational scientists active in the field of locoregional cancer spread. Numerous illustrations aid the reader throughout in the many facets of this disease.

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Perioperative and Critical Care Medicine : Educational Issues 2005

Continuing medical education and specialty training procedures represent highly dynamical processes, with a continuously evolving content. The specific teaching methods available (micro-teaching, team teaching, mastery learning, simulation, and e-learning) are essential elements of this process to promote professional updating and teaching at the bedside, aimed at providing an excellent clinical practice.

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Periodontitis : Advances in Experimental Research

Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. In each chapter: Abstract and main body (scientific audience and expert clinicians) Highlights (scientific audience and clinicians) Impact for Practice (clinicians and economical/political decision makers) Summary for Patients (patients and economical/political decision makers)

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Periodontal disease : Diagnosis, management options and clinical features

Periodontal disease (PD), an inflammatory disease of tooth supporting tissues that leads to progressive loss of periodontal ligament and bone, with pocket formation and / or recession of the gums, is widespread among the world adult population and a serious public health issue. In this book, Chapter One reviews the literature about the use of probiotics in periodontal disease, including in vitro, in vivo and clinical studies, in order to improve the understanding of probiotics’ role in periodontal disease and discusses the effectiveness of their use as a therapy for periodontitis. Chapter Two studies the model of periodontitis induction by ligature and presents a protocol for performing it in rats and mice, based on the experience of the authors’ research group, to guide researchers who wish to develop the model. Chapter Three focuses on nutritional and systemic risk factors for periodontitis, focusing on modifiable common risk factors that also impact cardiometabolic disease, which can be targeted through oral and medical health professionals for improving periodontal and cardiometabolic health. Chapter Four discusses the main manifestations of gingivitis, chronic periodontitis, aggressive periodontitis, and periodontal disease resulting from systemic diseases.

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Peri-implant soft tissue management : A clinical guide

Provides dentists who place dental implants with a thorough overview of how to deal with the various challenges that they are likely to face in delivering appropriate soft tissue management. Various modalities and techniques for handling soft tissue during the surgical and restorative phases are clearly described, with discussion of different flap designs and the implications of the patient’s medical condition.

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Percutaneous Vertebroplasty and Kyphoplasty

This new edition of the well-regarded original has been thoroughly revised by Drs. John M. Mathis, Hervé Deramond, and Stephen M. Belkoff to reflect recent advances in percutaneous vertebroplasty and kyphoplasty. Obsolete sections have been judiciously replaced with cutting-edge material, such as an in-depth look at the latest bone cements and devices. Chapters outline spine anatomy, medical management, and patient selection. The addition of practical and challenging case studies furthers the focus of the previous edition by bridging the gap between theory and practice for spine interventionalists, radiologists, neuroradiologists, orthopedic surgeons, and neurosurgeons. The text is enhanced by a wealth of illustrations.

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Percutaneous Tumor Ablation in Medical Radiology

Thermal ablation has become an integral part of oncology, especially in the field of interventional oncology. This very comprehensive book encompasses the different technologies employed in thermal ablation, its indications and the results achieved in various clinical conditions. The first part of the book clearly explains the basics of thermal ablative techniques such as laser-induced thermotherapy, radiofrequency ablation, microwave ablation, cryotherapy, and localized tumor therapy. The latest developments in the application of minimally invasive therapies in localized neoplastic disease are demonstrated. In the main part of the book, techniques of guiding the applicators to the target structures by use of different imaging tools such as ultrasound, computed tomography and magnetic resonance imaging are discussed.

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Perceiving Geometry : Geometrical Illusions Explained by Natural Scene Statistics

Understanding vision, whether from a neurobiological, psychological or philosophical perspective, represents a daunting challenge that has been pursued for millennia. During at least the last few centuries, natural philosophers, and more recently vision scientists, have recognized that a fundamental problem in biological vision is that the physical sources underlying sensory stimuli are unknowable in any direct sense. In vision, because physical qualities are conflated when the 3-D world is projected onto the 2-D image plane of the retina, the provenance of light reaching the eye at any moment is inevitably uncertain. This quandary is referred to as the inverse optics problem. The relationship of the real world and the information conveyed to the brain by light present a profound problem. Successful behavior in a complex and potentially hostile environment clearly depends on responding appropriately to the sources of visual stimuli rather than to the physical characteristics of the stimuli as such. If the retinal images generated by light cannot specify the underlying reality an observer must deal with, how then does the visual system produce behavior that is generally successful? Perceiving Geometry considers the evidence that, with respect to the perception of geometry, the human visual system solves this problem by incorporating past human experience of what retinal images have typically corresponded to in the real world.

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Peptide therapeutics : Fundamentals of design, development, and delivery

Explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues. It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. The book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides.

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Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules

This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the methods available for gene targeting and modification.

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