الصفحة 41
الصفحة 41
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Cellular Genetic Algorithms

CELLULAR GENETIC ALGORITHMS defines a new class of optimization algorithms based on the concepts of structured populations and Genetic Algorithms (GAs). The authors explain and demonstrate the validity of these cellular genetic algorithms throughout the book. This class of genetic algorithms is shown to produce impressive results on a whole range of domains, including complex problems that are epistatic, multi-modal, deceptive, discrete, continuous, multi-objective, and random in nature. The focus of this book is twofold. On the one hand, the authors present new algorithmic models and extensions to the basic class of Cellular GAs in order to tackle complex problems more efficiently. On the other hand, practical real world tasks are successfully faced by applying Cellular GA methodologies to produce workable solutions of real-world applications.

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Cell-Cell Channels

The biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. This concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap­ parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel­ ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc­ tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.

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Cell Stress Proteins

This comprehensive volume, written by experts in the field, provides a current understanding of the molecular properties of the heat shock proteins and their roles in health and disease. Cell Stress Proteins includes advances in several aspects of stress protein research, with chapters ranging from basic studies of the role of heat shock proteins in protein folding to reviews examining the breakdown of stress protein regulation during disease. It also provides analysis of the biochemical and molecular properties of heat shock proteins which can be utilized in evaluating their role in human physiology and pathology. Cell Stress Proteins is an ideal book for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.

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Cell Signaling in Vascular Inflammation

Although inflammatory disease of the vascular bed of the lung is a major cause of morbidity and mortality in both adult and pediatric age groups, the importance of vascular biology to its understanding, and in developing novel therapeutics, has been overlooked. In Cell Signaling in Vascular Inflammation, leading basic and clinical researchers review the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement.

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Cell Motility in Cancer Invasion and Metastasis

Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no therapies are aimed at the underlying mechanisms that enable this progression due to only nascent recognition of the distinct biology which occurs only during tumor dissemination. Recent advances have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book includes state-of-the-art updates by international leaders in these studies. Chapters first present the novel model systems that enable new investigations and insights. Chapters then describe in depth the key processes and molecules that may be therapeutically targeted. Finally, the role of cell motility and its signals is explored in a number of key tumor types. This compilation should be useful to researchers in basic and translational oncology as well as those developing novel agents to prevent tumor invasion and metastasis.

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Cell Division Control in Plants

The molecular mechanisms controlling cell cycle progression are highly conserved in eukaryotes. In addition to the basic protein machinery involved in cell cycle regulation, higher plants have also evolved unique molecular mechanisms that allow integration of environmental, physiological, and developmental signals into networks to control proper cell division and expansion. Rapid and exciting research progress in these fields has been achieved from experimental observations on plants over the past decade. The scope of this volume is focused on the molecular basis of all aspects of cell division and cytokinesis in plants. It is an essential reference book for instructors and scientists working in the areas of molecular, cell, and developmental biology of plants. The editors of this book are veterans in the field of plant molecular biology and highly respected worldwide.

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Cathodic Arcs : From Fractal Spots to Energetic Condensation

Cathodic Arcs: From Fractal Spots to Energetic Condensation is the first book in over a decade dedicated to the physics and technology of cathodic arcs. It includes a detailed account of arc history, a textbook-like introduction to cathode phenomena, and some basic physics of expanding plasmas; it deals with the infamous macroparticle issue and describes a host of practical plasma filter solutions. In contrast to previous books on cathodic arcs, the focus is on the relation of arc plasmas and their properties to surface modification and thin film deposition. The book contains sections on basic plasma physics and thin film materials science. It also deals with practical issues of coatings such as stress control and the often-underrated issue of the coating’s color. By stressing the fractal nature of cathode spots, the theme of fluctuations can be found throughout the book: fluctuations affect all plasma properties and thereby have consequences for plasma-based surface modifications and film growth.

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Categories for software engineering

This book provides a gentle, software engineering oriented introduction to category theory. Assuming only a minimum of mathematical preparation, this book explores the use of categorical constructions from the point of view of the methods and techniques that have been proposed for the engineering of complex software systems: object-oriented development, software architectures, logical and algebraic specification techniques, models of concurrency, inter alia. After two parts in which basic and more advanced categorical concepts and techniques are introduced, the book illustrates their application to the semantics of CommUnity – a language for the architectural design of interactive systems. "For computer scientists, this unique book presents Category Theory in a manner tailored to their interests and with examples to which they can relate." Ira Forman, IBM "This book applies little-known yet quite powerful formal tools from category theory to software structures: designs, architectures, patterns, and styles. Rather than focus on issues at the level of computational models and semantics, it instead applies these tools to some of the problems facing the sophisticated software architect.

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Casting : An Analytical Approach

For a long time, the die cast industry has used trial and error as a leading development method, resulting in tremendous growth in the utilisation of available CFD (computational fluid dynamics) software. This software allows the development of better products that maximise the advantages the die cast process has to offer. Casting: An Analytical Approach will refresh knowledge of the governing laws of the fluid dynamics that have an effect on die cast die and die cast process design. MATLAB® (MathWorks, Inc.) and Visual Basic® (Microsoft) code are listed in Casting: An Analytical Approach for every stage of product, die and die cast process design; providing better understanding of die and process design and simplifying calculations of the die cast die as well as the die cast process. Gas ventilation system calculations and fundamentals of compressible gas flow are also included.

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Cartooning made easy : Circle, triangle, square : Draw unique cartoon characters using simple geometric shapes

offers easy-to-follow instruction for using basic shapes to draw cute cartoon characters. Her approach is simple: All you need are basic drawing tools and shapes to cartoon! The book features dozens of drawing projects and step-by-step instruction perfect for beginning and aspiring artists, cartoonists, illustrators, pen and graphite artists, and many others. Each project combines simple geometric shapes—including circles and triangles and squares but also ovals, rectangles, and more—to draw adorable, cartoon-inspired artwork, including cartoon: Heads / Faces / Bodies / Unique characters / Animals, such as elephants / And more!

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Carotenoids ; Vol.4 : Natural Functions

The Carotenoids book series provides detailed accounts of the fundamental chemistry of carotenoids and the basic methods used in carotenoid research, and critical discussions of the biochemistry, functions and applications of these important compounds. Volume 4 and its companion, Volume 5, deal with the functions of carotenoids in all kinds of living organisms and the actions of carotenoids in human nutrition and health. The material presented in the earlier Volumes is all relevant to studies of biological functions and actions. In particular, biological studies must be supported by a rigorous analytical base. The various analytical procedures described in Volumes 1A and 1B, supplemented by the data for individual compounds given in the Carotenoids Handbook, must be understood and applied correctly, whether they are being used for quantitative analysis, identification or in complex studies of carotenoids in situ.

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Care of Astronomical Telescopes and Accessories : A Manual for the Astronomical Observer and Amateur Telescope Maker

guide for anyone who wants to understand more than just the basics of astronomical telescopes and accessories, and how to maintain them in the peak of condition. The latest on safely adjusting, cleaning, and maintaining your equipment is combined with thoroughly updated methods from the old masters. Here, too, are details of choosing new and used optics and accessories, along with enhancements you can make to extend their versatility and useful lifetime. This book is for you. Really. Looking after an astronomical telescope isn’t only for the experts - although there are some things that only an expert should attempt - and every serious amateur astronomer will find invaluable information here, gleaned from Barlow Pepin's many years’ experience working with optical instruments.

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Cardiovascular Disease in AIDS

In this new edition of Cardiovascular Disease in AIDS new insights coming from basic and clinical research in the field of HIV-associated cardiovascular disease and antiretroviral therapy are reported, along with the clinical guidelines for a careful stratification of the cardiovascular risk and cardiovascular monitoring of HIV-infected patients receiving HAART. The authors offer a wide overview of the topic for specialists in cardiology and infectious diseases involved in the clinical management of HIV-infected patients.

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Carbonate Reservoir Characterization : An Integrated Approach

One principal need in petroleum recovery from carbonate reservoirs is the description of the three-dimensional distribution of petrophysical properties in order to improve performance predictions by means of fluid-flow computer simulations. The book focuses on a rock based approach for the integration of geological, petrophysical, and geostatistical methods to construct a reservoir model suitable to input into flow simulation programs. This second edition includes a new chapter on model construction and new examples of limestone, dolostone, and touching-vug reservoir models as well as improved chapters on basic petrophysical properties, rock-fabric/petrophysical relationships, calibration of wireline logs, and sequence stratigraphy.

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Carbon Nanotubes : From Basic Research to Nanotechnology

A nanotube can bend easily but still is very robust. The nanotubes can be manipulated and contacted to external electrodes. Their diameter is in the nanometer range, whereas their length may exceed several micrometers, if not several millimeters. In diameter, the nanotubes behave like molecules with quantized energy levels, while in length, they behave like a crystal with a continuous distribution of momenta. Depending on its exact atomic structure, a single-wall nanotube –that is to say a nanotube composed of just one rolled-up graphene sheet– may be either a metal or a semiconductor. The nanotubes can carry a large electric current, they are also good thermal conductors.

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Carbon monoxide in drug discovery, basics, pharmacology, and therapeutic potential

Carbon monoxide, one of the smallest organic natural molecules, is widely known for its toxicity. Formation of CO via incomplete combustion is a major contributing factor to accidental or intentional CO poisoning, leading to severe health consequences or death. In addition, CO is a by-product of tobacco smoking, and has been associated with some of the harmful effects of smoking. However, less known and probably far more important is the recognition of the essential physiological roles of CO as a signaling molecule in mammals. Against over more than a century of negative connotation, the last few decades have proven that CO possesses a multitude of physiological roles and therapeutic functions including regulation of the immune response, cellular proliferation, and control of cell survival. This concept is supported by the discovery that CO is produced by all cells and more so under conditions of stress. This book comprehensively summarizes key aspects of CO's endogenous roles, therapeutic functions, and challenges that we face in its development as a therapeutic agent. We hope this preface will provide a thread for reading this book and a birds-eye view of the landscape for understanding this field, and more importantly lay out the challenges ahead in understanding the detailed mechanisms of action of CO and in its development as a therapeutic agent.

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Capacity options for revenue management : Theory and applications in the air cargo industry

Hellermann addresses in his dissertation one of the most interesting - pects of this evolution for OR/MS, the parallel development of long-term and short-term markets for capacity and output, accompanied by a range of option and ?xed-commitment (i. e. , forward) contracts as the basic mec- nisms supporting transactions. This has been a fascinating topic for OR/MS research because it builds on the powerful framework of real options, while connecting directly to key operations decisions (capacity planning, network design, staf?ng, routing, maintenance, and so forth) of the equipment and technologies whose output is the focus of contracts.

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Cancer grading manual

Cancer Grading Manual addresses all histopathologic aspects of tumor pathology essential for grading of tumors. It discusses the history and basic tenets of tumor grading; principles of microscopic grading of tumors; ancillary methods currently used to improve tumor grading; and new techniques used in evaluating tumors and formulating prognosis. It is designed to be a practice-oriented, concise and well-illustrated resource for diagnostic surgical pathologists and pathology residents.

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Calculus of one variable

Aimed at first-year undergraduates in mathematics and the physical sciences, the only prerequisites are basic algebra, coordinate geometry and the beginnings of differentiation as covered in school. The transition from school to university mathematics is addressed by means of a systematic development of important classes of techniques, and through careful discussion of the basic definitions and some of the theorems of calculus, with proofs where appropriate, but stopping short of the rigour involved in Real Analysis.The influence of technology on the learning and teaching of mathematics is recognised through the use of the computer algebra and graphical package MAPLE to illustrate many of the ideas.

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Calculus and mechanics on two-point homogenous riemannian spaces

The present monograph gives a short and concise introduction to classical and quantum mechanics on two-point homogenous Riemannian spaces, with empahsis on spaces with constant curvature. Chapter 1-4 provide the basic notations from differential geometry for studying two-body dynamics in these spaces. Chapter 5 deals with the problem of finding explicitly invariant expressions for the two-body quantum Hamiltonian. Chapter 6 addresses one-body problems in a central potential. Chapter 7 studies the classical counterpart of the quantum system of chapter 5. Chapter 8 investigates some applications in the quantum realm, namely for the coulomb and oscillator potentials.

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