الصفحة 40
الصفحة 40
Early Cancer of the Gastrointestinal Tract : Endoscopy, Pathology, and Treatment
Differences in the diagnostic criteria for early cancer of the gastrointestinal tract between Japan and Western countries have been an interesting issue for some time, physicians in Japan being much more inclined to give a diagnosis of cancer than their European and North American counterparts. This book addresses those differences by contrasting the views of Eastern and Western endoscopists and pathologists on 24 cases presented in Part I.
Early Aspects: Current Challenges and Future Directions ; 10th International Workshop, Vancouver, Canada, March 13, 2007, Revised Selected Papers
Traditionally, aspect-oriented software development (AOSD) has focused on the implementation phase of the software lifecycle: aspects are identified and captured mainly in code. Therefore, most current AOSD approaches place the burden for aspect identification and management on the programmer working at low levels of abstraction. However, aspects are often present well before the implementation phase, such as in domain models, requirements and software architecture. Identification and capture of these early aspects ensure that aspects related to the problem domain (as opposed to merely the implementation) will be appropriately captured, reasoned about and available. This offers improved opportunities for early recognition and negotiation of trade-offs and allows forward and backward aspect traceability. This makes requirements, architecture, and implementation more seamless, and allows a more systematic application of aspects.
Dynamics in Logistics ; 1st International Conference, LDIC 2007, Bremen, Germany, August 2007, Proceedings
This book comprises the edited proceedings of the first International Conference on Dynamics in Logistics LDIC 2007. The scope of the conference was concerned with the identification, analysis, and description of the dynamics of logistic processes and networks.
Dynamics in Logistics : Twenty-Five Years of Interdisciplinary Logistics Research in Bremen, Germany
Highlights the interdisciplinary aspects of logistics research. Featuring empirical, methodological, and practice-oriented articles, it addresses the modelling, planning, optimization and control of processes. Chiefly focusing on supply chains, logistics networks, production systems, and systems and facilities for material flows, the respective contributions combine research on classical supply chain management, digitalized business processes, production engineering, electrical engineering, computer science and mathematical optimization.
Dynamic Modeling of Monetary and Fiscal Cooperation Among Nations
The first four chapters introduce the reader to the dynamics of fiscal and monetary policy cooperation. Issues covered include: fiscal coordination, fiscal stringency requirements, structural and bargaining power asymmetries and the design of monetary and fiscal policymaking in a monetary union. In the four last chapters multiple-player settings with aspects of fiscal and/or monetary coordination are analyzed using the endogenous coalition formation approach. The analysis is focused on shock and model asymmetries and issues of multi-country coordination in the presence of (possibly many) monetary unions.
Dynamic characterisation of analogue-to-digital converters
Dynamic Characterisation of Analogue-to-Digital Converters presents a state of the art overview of the methods and procedures employed for characterising ADCs’ dynamic performance behaviour using sinusoidal stimuli. The three classical methods – histogram, sine wave fitting, and spectral analysis – are thoroughly described, and new approaches are proposed to circumvent some of their limitations
Drugs in palliative care
While palliative care has adopted a holistic approach to treatment / medication-driven symptom management ostensibly forms the critical aspect of care. Prescribing in palliative care can be extremely complex because the patient may often have comorbidity / or occasionally multimorbidity. The associated polypharmacy further complicates the pharmacological management of symptoms being caused by the palliative condition. This can be daunting for healthcare professionals and can negatively impact upon the effectiveness of care provided. Fully revised and updated / the third edition of Drugs in Palliative Care provides a detailed / yet concise overview of topics that are encountered in palliative care clinical practice. The book will appeal to a variety of healthcare professionals involved in the provision of palliative care and medicines information.
Drugs and Poisons in Humans : A Handbook of Practical Analysis
At the beginning of the book, general topics are addressed, including instructions on h- dling biological materials, measurement of drugs in alternative specimens, and guidance on resolving analytical problems that may occur. T ere are discussions of extraction modalities and detection methodologies and how to select these appropriately based on the physioche- cal characteristics of the drug. Analysis of specif c classes of drugs and relevant metabolites are covered in subsequent chapters.
Drugs and a methodological compendium : From bench to bedside
Provides a meticulous view on methodological drug discovery and development insights from bench to bedside. Focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. Covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.
Drug safety evaluation
Presents an all-inclusive practical guide for those who are responsible for developing new drugs and ensuring the safety of an ever-expanding spectrum of therapeutics. This book helps readers understand how the safety of these products are evaluated for use. Extensively revised to reflect up-to-date information, this edition includes changes to the scope of products (vaccines, small synthetic, large protein moieties, cells and tissues), harmonized global and national regulatory requirements, the therapeutic development process, and available technologies to identify and evaluate the relevance of potential patient risks
Drug interactions in infectious diseases : Mechanisms and models of drug interactions
Provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development
Drop acid
Our most respected scientific literature is bursting with evidence that elevated uric acid levels lie at the root of many pervasive health conditions, but mainstream medicine for the most part remains unaware of this connection. This is especially alarming because many people don’t know they are suffering from sky-high levels, putting them at risk for developing or exacerbating potentially life-threatening illnesses.
Doormaking : Materials, Techniques, and Projects for Building Your First Door
Starts first by addressing the fundamentals: the basics of good design and proper construction technique, the pros-and-cons of common materials including wood and sheet goods, interior and exterior finishes, hardware and the fine points of hanging doors. Once those key elements are covered, it offers project chapters that walk the reader step-by-step through the construction of eight essential doors, explaining design and material choices in specific contexts, tool options and other considerations. The first four projects are easly accessible to a beginner while the the remaining projects offer up some more challenging details for the intermediate woodworker. Also included are sidebars containing amusing anecdotes and mistake stories each delivering tips as well as details for hanging a door and an inspiring gallery of doors that are sure to inspire.
Domain-driven design with Java, a practitioner's guide : create simple, elegant, and valuable software solutions for complex business problems
Helps you as a developer and architect to put your knowledge to work in order to create elegant software designs that are enjoyable to work with and easy to reason about. You'll begin with an introduction to the concepts of domain-driven design and discover various ways to apply them in real-world scenarios. You'll also appreciate how DDD is extremely relevant when creating cloud native solutions that employ modern techniques such as event-driven microservices and fine-grained architectures. As you advance through the chapters, you'll get acquainted with core DDD's strategic design concepts such as the ubiquitous language, context maps, bounded contexts, and tactical design elements like aggregates and domain models and events. You'll understand how to apply modern, lightweight modeling techniques such as business value canvas, Wardley mapping, domain storytelling, and event storming, while also learning how to test-drive the system to create solutions that exhibit high degrees of internal quality.
DOM Scripting : Web Design with JavaScript and the Document Object Model
There are three main technologies married together to create usable, standards-compliant web designs: XHTML for data structure, Cascading Style Sheets for styling your data, and JavaScript for adding dynamic effects and manipulating structure on the fly using the Document Object Model. This book is about the latter of the three. DOM Scripting: Web Design with JavaScript and the Document Object Model gives you everything you need to start using JavaScript and the Document Object Model to enhance your web pages with client-side dynamic effects. Jeremy Keith starts off by giving you a basic crash course in JavaScript and the DOM, then moves on to provide you with several real-world examples built up from scratch, including dynamic image galleries and dynamic menus. Then, he shows you how to manipulate web page style using the CSS DOM, and create markup on the fly.
DNA damage detection : Methods and protocols
Explores techniques in DNA damage analysis, important not only for understanding cellular health after exposure to genotoxic agents but also for assessing cellular ability of genome maintenance. The book explores traditional DNA damage measurement methods, as well as modern fluorescence-based analysis and high throughput automatic analysis methods. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Distributed systems and mobile computing
About Distributed Systems and Mobile Computing. This is a branch of Computer Science devoted to the study of systems whose components are in different physical locations and have limited communication capabilities. Such components may be static, often organized in a network, or may be able to move in a discrete or continuous environment. The theoretical study of such systems has applications ranging from swarms of mobile robots (e.g., drones) to sensor networks, autonomous intelligent vehicles, the Internet of Things, and crawlers on the Web. The book includes five articles. Two of them are about networks: the first one studies the formation of networks by agents that interact randomly and have the ability to form connections; the second one is a study of clustering models and algorithms. The three remaining articles are concerned with autonomous mobile robots operating in continuous space.
Distributed systems : Concurrency and consistency
Explores the gray area of distributed systems and draws a map of weak consistency criteria, identifying several families and demonstrating how these may be implemented into a programming language. Unlike their sequential counterparts, distributed systems are much more difficult to design, and are therefore prone to problems. On a large scale, usability reminiscent of sequential consistency, which would provide the same global view to all users, is very expensive or impossible to achieve.
Distributed network systems : From concepts to implementations
This textbook covers both theoretical and practical aspects of distributed computing. It describes the client-server model for developing distributed network systems, the communication paradigms used in a distributed network system, and the principles of reliability and security in the design of distributed network systems. Based on theoretical introductions, the book presents various implementation strategies and techniques for building distributed network systems, including examples in TCP/IP communications, the use of remote procedure call and remote method invocation techniques, and the development of web-based applications, distributed databases, and mobile computing systems.
Distributed Cooperative Laboratories : Networking, Instrumentation, and Measurements
This is a highly interdisciplinary topic, where various aspects converge: multimedia communications and networking, sensor networks, Grid technology, Quality of Service (QoS) provisioning and control, network management, measurement instrumentation and methodology, architecture of measurement systems. The material is organized into six parts: Technologies for Real-Time Interactive Multimedia Communications; Monitoring, Management and Configuration of Networks and Networking Devices; Data Acquisition and Aggregation in Sensor Networks; Grid Structures for Distributed Cooperative Laboratories; Architectures and Techniques for Tele-Measurements; Virtual Immersive Communications and Distance Learning. Each contribution presents a self-contained treatment, within a framework that provides the reader with an up-to-date picture of the most recent state-of-the-art developments.
