Dynamic Analysis of Petri Net-Based Discrete Systems
Design of modern digital hardware systems and of complex software systems is almost always connected with parallelism. For example, execution of an object-oriented p- gram can be considered as parallel functioning of the co-operating objects; all modern operating systems are multitasking, and the software tends to be multithread; many complex calculation tasks are solved in distributed way. But designers of the control systems probably have to face parallelism in more evident and direct way. Controllers rarely deal with just one controlled object. Usually a system of several objects is to be controlled, and then the control algorithm naturally turns to be parallel. So, classical and very deeply investigated model of discrete device, Finite State Machine, is not expressive enough for the design of control devices and systems. Theoretically in most of cases behavior of a controller can be described by an FSM, but usually it is not convenient; such FSM description would be much more complex, than a parallel specification (even as a network of several communicating FSMs).
Dumbing Down : The Crisis of Quality and Equity in a Once-Great School System—and How to Reverse the Trend
This book examines the challenges and issues caused by a move to a marketized education system in Sweden. Observing the introduction of the school voucher system and a postmodern social constructivist view of knowledge, the move away from objective knowledge is identified as the core reason for Sweden’s current education crisis. The impact of declining education standards on the labor market is also discussed.
Drugs in palliative care
While palliative care has adopted a holistic approach to treatment / medication-driven symptom management ostensibly forms the critical aspect of care. Prescribing in palliative care can be extremely complex because the patient may often have comorbidity / or occasionally multimorbidity. The associated polypharmacy further complicates the pharmacological management of symptoms being caused by the palliative condition. This can be daunting for healthcare professionals and can negatively impact upon the effectiveness of care provided. Fully revised and updated / the third edition of Drugs in Palliative Care provides a detailed / yet concise overview of topics that are encountered in palliative care clinical practice. The book will appeal to a variety of healthcare professionals involved in the provision of palliative care and medicines information.
Drug transporters : Molecular characterization and role in drug disposition
Drug Transporters: Molecular Characterization and Role in Drug Disposition provides in-depth analysis of the conceptual evolution and technical development for studying drug transporters. Contributions by an international panel of leading researchers address advances in transporters as drug targets, transporters in pharmacotherapy, the impact of transporters on drug efficacy and safety, the development of sophisticated model systems and sensitive assay methods, and more. Divided into two parts, the book first provides a thorough overview of relevant drug transporters before detailing the principles of drug transport and associated techniques.
Drug discovery with privileged building Blocks : Tactics in medicinal chemistry
Drug Discovery with Privileged Building Blocks traces back PharmaBlock’s founding philosophy of designing privileged building blocks. High-quality building blocks are crucial not only to biological activities of different molecules but also to ADMET properties, which eventually will impact the success rate of drug discovery projects. A thorough study of how building blocks perform in drug molecules and a regular analysis of new building block structures in the latest researches have proven to be a fruitful strategy to generate novel building blocks. Using this strategy, PharmaBlock has supplied the drug industry with a great number of building blocks, which are increasingly being adopted by drug hunters, and these are identified in this book.
Drug development and approval process
Drug discovery is the process of identifying and characterizing molecules with the potential to safely modulate disease, with a goal to bring medicines that can improve the lives of patients. It is a lengthy and resource intensive process, that requires close cooperation across multiple disciplines. Optimizing the process of drug discovery is of great interest to the pharmaceutical industry, as the efficient identification and selection of suitable drug candidates can have a dramatic impact on the cost and profitability of new medicines.
Drawing the Ground - Landscape Urbanism Today : The Work of Palmbout Urban Landscapes
Documents some fifteen projects organized into six thematic blocks, including such extensive projects as Amsterdam Ijburg, a design for an urban extension to Amsterdam with a total area of 450 hectares, 18,000 residences, 100,000 square meters of office space, 30,000 square meters of stores, and other facilities, and Maastricht Belvedere, a restructuring of 280 hectares of a former industrial site with 4,000 residences, 100,000 square meters of office space, parking lots, and a vehicle bridge.
Drawing for Interior Designers
The perfect guide to producing successful hand drawings of interior designs. Sitting quietly at home, sketchbook in hand, is the ideal way to tackle drawing. In fact, your home is an absolute mine of subjects to draw. Perhaps you already have a plan in your head for a makeover or conversion? This book is filled with practical principles which will help you put your plans down on paper and better express your ideas, for no serious project gets made without a progressive plan. Teaches you some tricks of the trade and conventions which are part of an architect's know-how and which will help you with ideas. Packed with beautiful sketches, provides advice from drawing perspective, floor plans and furniture to rendering rooms and taking down a partition wall.
Domain-driven design with Java, a practitioner's guide : create simple, elegant, and valuable software solutions for complex business problems
Helps you as a developer and architect to put your knowledge to work in order to create elegant software designs that are enjoyable to work with and easy to reason about. You'll begin with an introduction to the concepts of domain-driven design and discover various ways to apply them in real-world scenarios. You'll also appreciate how DDD is extremely relevant when creating cloud native solutions that employ modern techniques such as event-driven microservices and fine-grained architectures. As you advance through the chapters, you'll get acquainted with core DDD's strategic design concepts such as the ubiquitous language, context maps, bounded contexts, and tactical design elements like aggregates and domain models and events. You'll understand how to apply modern, lightweight modeling techniques such as business value canvas, Wardley mapping, domain storytelling, and event storming, while also learning how to test-drive the system to create solutions that exhibit high degrees of internal quality.
Domain Decomposition Methods - Algorithms and Theory
This book offers a comprehensive presentation of some of the most successful and popular domain decomposition preconditioners for finite and spectral element approximations of partial differential equations. It places strong emphasis on both algorithmic and mathematical aspects. It covers in detail important methods such as FETI and balancing Neumann-Neumann methods and algorithms for spectral element methods.
Do Exclusionary Rules Ensure a Fair Trial? : A Comparative Perspective on Evidentiary Rules
This publication discusses exclusionary rules in different criminal justice systems. It is based on the findings of a research project in comparative law with a focus on the question of whether or not a fair trial can be secured through evidence exclusion. Part I explains the legal framework in which exclusionary rules function in six legal systems: Germany, Switzerland, People’s Republic of China, Taiwan, Singapore, and the United States. Part II is dedicated to selected issues identified as crucial for the assessment of exclusionary rules. These chapters highlight the delicate balance of interests required in the exclusion of potentially relevant information from a criminal trial and discusses possible approaches to alleviate the legal hurdles involved.
Distributed systems and mobile computing
About Distributed Systems and Mobile Computing. This is a branch of Computer Science devoted to the study of systems whose components are in different physical locations and have limited communication capabilities. Such components may be static, often organized in a network, or may be able to move in a discrete or continuous environment. The theoretical study of such systems has applications ranging from swarms of mobile robots (e.g., drones) to sensor networks, autonomous intelligent vehicles, the Internet of Things, and crawlers on the Web. The book includes five articles. Two of them are about networks: the first one studies the formation of networks by agents that interact randomly and have the ability to form connections; the second one is a study of clustering models and algorithms. The three remaining articles are concerned with autonomous mobile robots operating in continuous space.
Distributed computing and Internet Technology ; 1st International Conference, ICDCIT 2004, Bhubaneswar, India, December 22-24, 2004, Proceedings
Taming the Dynamics of Disributed Data - DISTRIBUTED COMPUTING -- Data in Your Space -- Enabling Technologies for Harnessing Information Explosion -- Fair Leader Election by Randomized Voting -- An Efficient Leader Election Algorithm for Mobile Ad Hoc Networks -- Distributed Balanced Tables: A New Approach - Performance Evaluation of Gigabit Ethernet and SCI in a Linux Cluster -- Performance Evaluation of a Modified-Cyclic-Banyan Based ATM / IP Switching Fabric -- A Scalable and Robust QoS Architecture for WiFi P2P Networks -- NEC: Node Energy Based Clustering Protocol for Wireless Sensor Networks with Guaranteed Connectivity,and other
Distant Worlds : Milestones in Planetary Exploration
Peter Bond provides an overview of key, unmanned missions, chapter by chapter, to planets in the twentieth century. He tells the story of the mission planners and engineers who, working mostly in the background, made these unprecedented achievements in scientific exploration possible.
Disseminative Capabilities : A Case Study of Collaborative Product Development in the Automotive Industry
Nowadays, cooperating in Product Development seems to be a dominant strategy to lower costs and risks, to fully utilize capacities, and to gain access to lacking knowledge assets. Oppat analyzes cooperations in Product Development with a special focus on the automotive industry. He seeks answers to the question of how knowledge transfer between involved partners takes place. Although knowledge transfer and its success levers (e.g. absorptive capacity) are well-researched phenomena, equivalent investigations of the sender and her capabilities (DiC - Disseminative Capabilities) impacting inter-organizational transfer success are lacking. The in-depth case studies conducted concentrate on joint car development projects between Magna Steyr, an Austrian-based company, and German-based BMW, Mercedes Benz, and Audi. The research results clearly indicate that DiC have an impact on the knowledge transfer process and can explain why the analyzed projects differ in terms of transfer success. Based on the research findings, this work provides managerial implications for all eight dimensions of DiC and, by deploying insights from the empirical investigations, outlines ways to develop them successfully.
Dissecting the Molecular Anatomy of Tissue
The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.
Disfluency and Proficiency in Second Language Speech Production
This book explores the concept of disfluency in speech production, particularly as it occurs in the context of second language acquisition. Drawing on examples from learner speech at three levels (beginner, intermediate and advanced), the author argues that acquiring target language norms for performing disfluency is essential to an individual being recognized as fluent in a language by fellow-speakers. Starting with a survey of the psycholinguistic research in this area, he then applies a sociolinguistic lens to examine how a learner's social and educational background impacts the types of disfluencies in their speech.
Discrete Geometry for Computer Imagery ; 14th IAPR International Conference, DGCI 2008, Lyon, France, April 16-18, 2008. Proceedings
This book constitutes the refereed proceedings of the 14th IAPR TC-18 International Conference on Discrete Geometry for Computer Imagery, DGCI 2008, held in Lyon, France, in April 2008.
Discrete and computational geometry; Japanese Conference, JCDCG 2004, Tokyo, Japan, October 8-11, 2004
This book constitutes the thoroughly refereed post-proceedings of the Japanese Conference on Discrete Computational Geometry, JCDCG 2004, held in Tokyo, Japan in October 2004, to honor Janos Pach on his fiftieth year. The 20 revised full papers presented were carefully selected during two rounds of reviewing and improvement from over 60 talks at the conference. All current issues in discrete algorithmic geometry are addressed.
Discovering Biomolecular Mechanisms with Computational Biology
In this anthology, leading researchers present critical reviews of methods and high-impact applications in computational biology that lead to results that also non-bioinformaticians must know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation. Discovering Biomolecular Mechanisms with Computational Biology is essential reading for life science researchers and higher-level students that work on biomolecular mechanisms and wish to understand the impact of computational biology for their success.



















