الصفحة 4
الصفحة 4
Handbook of medicinal plants of the world for aging : Botany, ethnopharmacology, natural Products, and molecular pathways
Provides an unprecedented comprehensive overview of more than 100 plants used globally as medicine with the potential to prevent premature aging. It is covers the pathophysiology of aging from the molecular and cellular to the organ levels, as well as the current state of knowledge about the modes of action of natural products from plants on the pathophysiological pathways related to the (i) cardiovascular system and metabolism, (ii) central nervous system, (iii) kidneys, (iv) bones, (v) skin and hair, and (vi) immune system.
Handbook of healthcare in the Arab World
Examines health and medical care in the Arab world from a systems biology approach. It features comprehensive coverage that includes details of key social, environmental, and cultural determinants. In addition, the contributors also investigate the developed infrastructure that manages and delivers health care and medical solutions throughout the region. More than 25 sections consider all aspects of health, from cancer to hormone replacement therapy, from the use of medications to vitamin deficiency in emergency medical care. Chapters highlight essential areas in the wellbeing and care of this population. These topics include women’s health care, displaced and refugee women’s health needs, childhood health, social and environmental causes of disease, health systems and health management, and a wide range of diseases of various body systems. This resource also explores issues related to access and barriers to health delivery throughout the region.
Handbook of Cardiovascular CT : Essentials for Clinical Practice
Handbook of Cardiovascular CT: Essentials for Clinical Practice has been created as a primer to assist cardiologists, radiologists and other readers involved in cardiac imaging, this book’s compact format provides a handy reference tool and provides the answers to important cardiovascular CT questions.
Handbook of cardiovascular behavioral medicine
Cardiovascular disease is the leading cause of morbidity and mortality in the United States and worldwide. It is well recognized that traditional risk factors for cardiovascular disease have limited predictive utility in the identification of new cardiovascular disease cases and outcomes. Thus, investigators have argued that application of a biopsychosocial research paradigm in this field may be of particular utility in understanding cardiovascular disease pathogenesis. Accordingly, a subdiscipline within the field of behavioral medicine – cardiovascular behavioral medicine – examines interrelations among biological, behavioral, psychological, social, and environmental factors in cardiovascular health and disease.
Handbook of cardiac anatomy, physiology, and devices
Because of rapid growth in the medical device industry-which today enjoys revenues as large as those of the automobile industry-as well as in our understanding of cardiac disease processes, biomedical engineers must cope with a rising tide of highly complex information. In Handbook of Cardiac Anatomy, Physiology, and Devices, leading experts from the University of Minnesota's renowned Lillehei Heart Institute and scientists from Medtronic, Inc. have compiled a concise-yet detailed and comprehensive-reference source on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Here, active bioengineers working on cardiac devices will find the complete critical background they need to understand cardiac pacing, defibrillation, cardiac repair using stem cell therapy, robotics, less invasive cardiac surgery, biventricular pacing, cardiac bioenergetics, and more. Insightful chapters address animal models for cardiac research, cardiac mapping systems, heart valve disease, ventricular assist devices, and genomics-based tools and technology.
Guyton and Hall textbook of medical physiology
Employs a distinctive format to ensure maximum learning and retention of complex concepts. A larger font size emphasizes core information, while supporting information, including clinical examples, are detailed in smaller font and highlighted in pale blue - making it easy to quickly skim the essential text or pursue more in-depth study. This two-tone approach, along with other outstanding features, makes this bestselling text a favorite of students worldwide. Offers a clinically oriented perspective written with the clinical and preclinical student in mind, bridging basic physiology with pathophysiology. Focuses on core material and how the body maintains homeostasis to remain healthy, emphasizing the important principles that will aid in later clinical decision making. Presents information in short chapters using a concise, readable voice that facilitates learning and retention. Contains more than 1,200 full-color drawings and diagrams - all carefully crafted to make physiology easier to understand. Features expanded clinical coverage including obesity, metabolic and cardiovascular disorders, Alzheimer's disease, and other degenerative diseases.
Genetic Engineering of Mesenchymal Stem Cells
MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of repairing tissues, speeding stem cell engraftment, and targeting solid tumors for specific killing, using MSC easily harvested from bone marrow, or better yet, from unwanted fat tissue, holds broad appeal, and is an intriguing possibility that could have dramatic effect on health care. This book has information on how to isolate, grow, and characterize MSC from marrow and fat, and gives important insight into how these cells may be used for gene delivery and cellular therapies in the future. Updates on emerging clinical trials are given.
General Medicine and Surgery for Dental Practitioners
Aimed at the practising clinician provides a welcome detailed overview of the medical and surgical conditions that affect patients seen in everyday dental practice.
Gender, Health and Ageing : European Perspectives on Life Course, Health Issues and Social Challenges
The objective of this book is to provide an overview of gender, health and ageing. Important theoretical concepts, such as life course and "Lebenslagen" in old age, or differences in men's health, are introduced. It is increasingly important to build a European basis of knowledge, to conduct discussions on European research findings, and to develop European research frameworks. In this volume, central theoretical debates on gender impacts on life course and old-age health, and vital issues of health research in the context of gender and old age are introduced. Specific aspects, such as the impact of gender and age on cardiovascular health, elder abuse and mental health, or care between gender relations, gender roles and gender constructs, are pointed out.
Gases and Toxins that Cause Pulmonary Edema
Pulmonary edema is a major health problem in the lung, it is a cardinal feature of congestive heart failure. Pulmonary edema defined as excessive extravascular water in the lungs, is a common and serious clinical problem. Pulmonary edema can be life-threatening, but effective therapy is available to rescue patients from the deleterious consequences of disturbed lung fluid balance, which usually can be identified and, in many instances, corrected. So we like to talk about this common disease because of its importance and its wide spread around the world. Other important causes of pulmonary edema are human exposure to some gases and toxins, the most important of which is chlorine gas, phosgene, mustard gas, heroin, paraquat and ammonia. This research paper will discuss also the procedures that are included, as well as a wider knowledge of these toxins and gases.
Fundamentals of Space Medicine
Topics discussed in this book include: adaptation of sensory-motor, cardio-vascular, bone, and muscle systems to the microgravity of spaceflight; psychological and sociological issues of living in a confined, isolated, and stressful environment; operational space medicine, such as crew selection, training and in-flight health monitoring, countermeasures and support; results of space biology experiments on individual cells, plants, and animal models; and the impact of long-duration missions such as the human mission to Mars. The author also provides a detailed description of how to fly a space experiment, based on his own experience with research projects conducted onboard Salyut-7, Mir, Spacelab, and the Space Shuttle. Now is the time to look at the future of human spaceflight and what comes next. The future human exploration of Mars captures the imagination of both the public and the scientific community. Many physiological, psychological, operational, and scientific issues need to be solved before the first crew can explore the enigmatic Red Planet. This book also identifies the showstoppers that can be foreseen and what we need to learn to fully understand the implications and risks of such a mission.
Functional Hemodynamic Monitoring
Hemodynamic monitoring is one of the major diagnostic tools available in the acute care setting to diagnose cardiovascular insufficiency and monitor changes over time in response to interventions. However, the rationale and efficacy of hemodynamic monitoring to affect outcome has come into question. We now have increasing evidence that outcome from critical illness can be improved by focused resuscitation based on existing hemodynamic monitoring, whereas non-specific aggressive resuscitation impairs survival. Thus, this book frames hemodynamic monitoring into a functional perspective wherein hemodynamic variables and physiology interact to derive performance and physiological reserve estimates that themselves drive treatment. This philosophy, as well as the limitations and applications of common and evolving hemodynamic measures and their focused use in the care of critically ill patients are discussed, relevant to one underlying truth: No monitoring device, no matter how simple or sophisticated, will improve patient-centered outcomes useless coupled to a treatment which, itself, improves outcome.
Fluid volume monitoring with glucose dilution
Decision making regarding fluid volume loading, fluid restriction, or administration of vasoactive drugs may vary among physicians, depending solely upon their clinical experience in the absence of evidence-based measurement. The initial distribution volume of glucose (IDVG) is believed to be clinically relevant as a marker of cardiovascular and fluid management in critically ill patients without a significant modification of glucose metabolism. This book covers all aspects of IDVG measurement, including the basic concept, its relationship with other fluid volumes, and the clinical application of this technique in the intensive care unit based on both the authors’ studies and their clinical experience with more than 4000 IDVG determinations. When the concept of IDVG is properly understood and its measurement is then performed routinely, daily fluid and cardiovascular management in critically ill patients can be improved based on evidence-based measurement.
Flavonoids as nutraceuticals
Flavonoids are well-known plant metabolites that have extraordinary properties that can be used for treating health issues. The pharmaceutical importance of flavonoids is due to their anti-depressant, anti-viral, anti-inflammatory, and antioxidant capacities. They are also of great importance when it comes to neuroprotection, cardiovascular disorders, and many types of cancer. Flavonoids are also easily available and produce less harmful side effects than some conventional therapeutics. This new volume examines the growing use of flavonoids for prevention and treatment of diseases and discusses their beneficial mechanisms. Chapters in the volume address diverse uses as anti-aging tools, as anti-inflammatory agents, for treating pregnancy-induced disorders, as a promising tool to combat infection of Covid-19, etc. The book explores their specific therapeutic antiviral potentials, the gene expression by flavonoids, and the role of flavonoids in agriculture.
Etiology and Morphogenesis of Congenital Heart Disease : From Gene Function and Cellular Interaction to Morphology
This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration
Essentials of Restenosis : For the Interventional Cardiologist
Essentials of Restenosis provides the practicing cardiologists and biologists an elaborate review of the current advances in the field. The book explore the process of restenosis from bench to bedside, encompassing in equal detail the newest scientific findings of the biological mechanisms as well as the progression in development of diagnostics and treatments. The volume also provides the reader with a basic understanding of the biological process and the latest diagnostics and treatments of the disease, with an up-to-date detailed discussion of the most important recent findings.
Essentials of pharmacodynamics and drug action
Provides a comprehensive exploration of the dynamic field of pharmacology and its fundamental principles. It delves into the intricate interactions between drugs and the human body, focusing on pharmacokinetics, which explains the dynamics of drug actions in the body, and pharmacodynamics, which uncovers the mechanisms through which drugs exert their effects. The book also emphasizes the crucial aspects of therapeutics and gene-based therapy, shedding light on modern approaches to disease treatment.
Essential Cardiology : Principles and Practice
The ideal textbook of cardiology lies between the very detailed and enormous encyclopedias of cardiology and the diminutive manuals and handbooks that provide a quick but superficial tour of the field. Clive Rosendorff, md, phd, and a panel of researchers and clinician-scientists, who are all leaders in their fields, create such a text with their second edition of Essential Cardiology: Principles and Practice. Drawing on years of practical experience, as well as the enormous number of recent scientific and clinical advances.
Enhancing the Role of Ultrasound with Contrast Agents
This bookprovides an up-to-date overview on the clinical value of contrast agents in ultrasound. The volume moves from a background section on technique and methodology to the main sections on the clinical application of contrast ultrasound in the liver and in vascular diseases. A final section discusses results and prospects of contrast ultrasound modality in the other fields.
Enhancing the Dissolution Rate of Atorvastatin by Solid Dispersion Technique
In the last few decades, solid dispersion (SD) technology had been studied as an approach to produce an amorphous carrier to enhance the solubility, dissolution rate, and bioavailability of poorly water-soluble drugs. The use of suitable carrier and methodology in the preparation of SDs play a significant role in the biological behavior of the SDs. Atorvastatin is a statin group HMG-CoA reductase inhibitor drug that is commonly used to adverse cardiovascular events and to lower blood total cholesterol and LDL-cholesterol. the solubility of atorvastatin in water is very low (0.1 mg mL− 1), which results in reduced bioavailability. In order to enhance its solubility, we have prepared solid dispersions (SDs) of atorvastatin at different drug: polymer ratios (1:2, 1:10, 1:20,1:25 and 1:40), using polyethylene glycol 6000 as polymer and different preparation methods (co-precipitate and melting methods) The characterization of the SDs was performed using differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) The solubility of AT was improved by the incorporation PEG6000.
