الصفحة 4
الصفحة 4
Methods of Cancer Diagnosis, Therapy and Prognosis : Breast Carcinoma
Focusing on Breast Carcinoma, this first volume in the series Methods of Cancer Diagnosis, Therapy and Prognosis brings together 56 leading scientists from around the world to deliver a comprehensive treatise on all aspects of breast cancer, including diagnosis, treatments and prognosis.
Mesoscale Analysis of Hydraulics
Presents a series of complicated hydraulic phenomena and related mechanism of high-speed flows in head-head dam. According to the basic hydraulic theory, detailed experiments and numerical simulations, microscopic scale analysis on cavitation bubbles, air bubbles, turbulent eddy vortices and sand grains are examined systemically. These investigations on microscopic fluid mechanics, including cavitation erosion, aeration protection, air–water flow, energy dissipation and river-bed scouring, allow a deep understanding of hydraulics in high-head dams. This book provides reference for designers and researchers in hydraulic engineering, environment engineering and fluid mechanics.
Introduction to Systems Biology
Informative and cutting-edge, this volume presents a clear and intuitive illustration of the biological systemic approaches and introduces ideal computational methods for research. Introduction to Systems Biology is an indispensable resource, providing a first glimpse into the state-of-the-art in systems biology.
Introduction to basics of pharmacology and toxicology ; Vol.2 : Essentials of systemic pharmacology : From principles to practice
Describes the pharmacology of drugs acting on different systems in the human body Analyses various human diseases and the pharmacological agents governing them Provides a valuable reference resource for academicians, researchers, and clinical practitioners Offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics.
Intraperitoneal Cancer Therapy
The volume details major clinical trails to date, including immunotherapy, hyperthermic treatment of colo-rectal and ovarian cancers. Authors also examine regional approaches to therapy, systemic therapy, and the use of carboplatin and paclitaxel as the standard treatment for women with stages III and IV ovarian cancer. Other chapters also investigate techniques and procedures in treatment, as well as the future direction of both normothermic and hyperthermic intraperitoneal chemotherapy.
Internationalization and Economic Policy Reforms in Transition Countries
The project is devoted to analyzing the internationalization of the Russian economy and the associated changes in major policy fields. This book contains the revised analytical papers from the St. Petersburg conference in 2003 when the city celebrated its 300 year anniversary. We are very grateful to the Leontief Center for excellent organization of the conference.
Internal medicine for dental treatments: patients with medical diseases
Illustrates the precautions for dental treatment with patients with medical diseases and presents the correlation and relationship between oral symptoms and systemic diseases. It is organized into two parts; the first part is symptomatology presenting the description of some symptoms as general remarks. Then comes the part explaining the diseases, which describe the associations between each medical disease and the oral conditions. Chapters provide intraoral figures and in-depth information to help readers understand the symptoms, mechanisms, and responses, the comorbidities, and medications.
Intelligent Organizations : Powerful Models for Systemic Management
This innovative book opens a path to overcoming the crisis of management in the face of complexity. The systems approach on which this work is grounded enables the development of the new kind of intelligent organizations so urgently needed. Powerful models, grounded in organizational cybernetics and system dynamics
Innovation Policy in a Knowledge-Based Economy : Theory and Practice
Why Analyze Innovation Policies From a Knowledge- Based Perspective? It is broadly accepted that we have moved (or are moving) to a knowled- based economy, characterized at least by two main features: that knowl edge is a major factor in economic growth, and innovation processes are systemic by nature. It is not surprising that this change in the economic paradigm requires new analytical foundations for innovation policies. One of the purposes of this book is to make suggestions as to what they should include. Underpinning all the chapters in this book is a conviction of the impor tance of dynamic and systemic approaches to innovation policy. Nelson and Arrow saw innovation and the creation of new knowl edge as the emergence and the diffusion of new information, characterized essentially as a public good. The more recent theoretical literature regarded the rationale for innovation policies as being to provide solutions to "mar ket failures". Today, however, knowledge is seen as multidimensional (tacit vs. codified) and open to interpretation. Acknowledging that the creation, coordination and diffusion of knowledge are dynamic and cumu lative processes, and that innovation processes result from the coordination of distributed knowledge, renders the "market failure" view of innovation policies obsolete. Innovation policies must be systemic and dynamic
Innovation in European Freight Transportation : Basics, Methodology and Case Studies for the European Markets
Serious problems and risks can be observed in European freight transportation development. However, the transport and logistics sector shows a lack of tradition in utilising systematic innovation management to overcome these problems. Hence, this volume puts forward a specific and comprehensive Systemic Migration-Oriented Innovation Management Method.
Inflammatory Bowel Disease : From Bench to Bedside
Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders are explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.
Inflammation and natural products ; 1st ed.
Brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes.
Higher Education in Romania : Overcoming Challenges and Embracing Opportunities
The book focuses on areas of interest for Romanian higher education, such as systemic measures to improve access, participation and completion for (vulnerable) students, better promotion of the Romanian higher education to attract students, as well as instruments for a more efficient use of data at higher education level. Each article includes evidence-based policy proposals that could support new strategic initiatives in higher education, including new legislation.
Handbook of Pediatric Eye and Systemic Disease
Concise yet comprehensive, the chapters in this handbook are reader friendly, organized with clear sub-headings to quickly guide the reader to areas of interest. Excellent, detailed color photographs and diagrams illustrate and enhance the clinical pearls. Extensive use of tables and information boxes helps to simplify and summarize complex topics.Also included is a comprehensive outline of the ocular manifestation of inherited diseases. This chapter provides a clinical snapshot of dozens of congenital conditions and their ocular manifestations.
Guide to periodontal treatment solutions for general dentistry
A concise textbook on periodontics geared towards dental students, residents, and early career general dentists. Each chapter includes cases and evidence-based practice exercises that illustrate key concepts and enable application of these concepts through independent study or non-lecture based teaching methods. This book is arranged in a logical sequence mirroring the manner in which patients present with periodontal disease, from the initial exam to state-of-the art treatments. The opening chapters cover gingivitis and disease basics, data collection, epidemiology, classification systems, and diagnosis. Subsequent chapters encompass a wide array of nonsurgical and surgical approaches for treating issues such as gum pockets, furcation, gingival recession, mucogingival defects, and tooth mobility, as well as when to refer patients. The latest methods for controlling gingival inflammation are discussed, including scaling and root planing, systemic and local antimicrobial therapy, antiseptics, lasers, and photodynamic therapy
Governance : Systemic foundation and framework
Instead of yet another theory on good governance, this book presents a substantiation of contemporary notions. It builds on the theoretical foundations for taking an overall perspective on social contexts and culminates in a systemic framework that captures social structures based on first principles of viability and sustainability. The framework at hand enables applicants to view social contexts holistically while at the same time envisioning a rich picture of what leverages the implementation of social purposes beyond the boxes of the professional disciplines: social structures can be assessed, strengths and weaknesses identified and measures arrived at. Ultimately, the required structures can be tailor-made to align forces for a joint implementation of purposes. Conventional static hierarchies can be deployed into dynamic social organisms capable of developing and adapting continuously according to the opportunities and challenges faced.
Gene Therapy for Cancer
The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer. Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing number of obstacles. These obstacles include vector systems that do not reach systemic metastases, therapeutic genes with redundant mec- nisms allowing for cellular resistance, and toxicities in clinical trials leading to premature closure of these studies. Different tactics to overcome or circumvent these obstacles have catalyzed the development of a wide range of gene therapy approaches. Thus far, almost two-thirds of gene therapy trials have focused on cancer. This reflects the concept that gene therapy approaches for the treatment of cancer do not necessarily require long-term expression of the gene as is necessary for the treatment of primary genetic defects like hemophilia or juvenile diabetes.
Fluconazole : Pharmacology, clinical uses and health effects
Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. In this book, the authors present current research in the study of the pharmacology, clinical uses and health effects of fluconazole. Topics discussed include the utilization of fluconazole in adult intensive care units; the use of fluconazole in veterinary species and a description of variances from the human experience as well as findings in veterinary species which may have applicability in human medicine; common clinical uses and in vitro activity features on fluconazole; and the discovery and development of medically-important antifungal agents, particularly the azole derivatives and the development of fluconazole and its clinical applications.
Financial crisis management and democracy : Lessons from Europe and Latin America
This book discusses financial crisis management and policy in Europe and Latin America, with a special focus on equity and democracy. Based on a three-year research project by the Jean Monnet Network, this volume takes an interdisciplinary, comparative approach, analyzing both the role and impact of the EU and regional organizations in Latin America on crisis management as well as the consequences of crisis on the process of European integration and on Latin America’s regionalism.
Evidence based practice in Neuro-oncology
This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects.
