الصفحة 4
الصفحة 4
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Multiscale Problems in the Life Sciences : From Microscopic to Macroscopic

The aim of this volume that presents Lectures given at a joint CIME and Banach Center Summer School, is to offer a broad presentation of a class of updated methods providing a mathematical framework for the development of a hierarchy of models of complex systems in the natural sciences, with a special attention to Biology and Medicine. Mastering complexity implies sharing different tools requiring much higher level of communication between different mathematical and scientific schools, for solving classes of problems of the same nature. Today more than ever, one of the most important challenges derives from the need to bridge parts of a system evolving at different time and space scales, especially with respect to computational affordability. As a result the content has a rather general character; the main role is played by stochastic processes, positive semigroups, asymptotic analysis, kinetic theory, continuum theory and game theory.

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Multiscale Methods : Averaging and Homogenization

This introduction to multiscale methods gives readers a broad overview of the many uses and applications of the methods. The book begins by setting the theoretical foundations of the subject area, and moves on to develop a unified approach to the simplification of a wide range of problems which possess multiple scales, via perturbation expansions; differential equations and stochastic processes are studied in one unified framework. The book concludes with an overview of a range of theoretical tools used to justify the simplified models derived via the perturbation expansions.

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Multiobjective Problem Solving from Nature : From Concepts to Applications

he book focuses on how MOEAs and related techniques can be used to solve problems, particularly in the disciplines of science and engineering. Contributions by leading researchers show how the concepts of multiobjective optimization can be used to reformulate and resolve problems in broad areas such as constrained optimization, coevolution, classification, inverse modelling and design. The book is distinguished from other texts on MOEAs in that it is not primarily about the algorithms, nor specific applications, but about the concepts and processes involved in solving problems using a multiobjective approach. Each chapter contributes to the central, deep concepts and themes of the book: evaluating the utility of the multiobjective approach; discussing alternative problem formulations; showing how problem formulation affects the search process; and examining solution selection and decision making.

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Mule 2 : A Developers Guide

Mule 2: A Developer's Guide introduces the Mule 2.0 integration platform for developers of enterprise integration applications who wish to leverage Mule as a lightweight messaging framework that contains a distributable object broker for managing communication between applications. The book is based on insight, knowledge, and experience resulting from working with Mule. The text provides support, consulting, and training to developers implementing Mule in a broad range of scenarios ranging from small projects through to large corporations developing major deployments.

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Mud and Mudstones : Introduction and Overview

Our book provides the first elementary overview of mud and mudstone written for a broad spectrum of professionals, teachers and students in geology, petroleum geology and engineering, urban planning and development, paleontology and paleoecology, and architecture and archaeology. Mud and mudstone provide the foundations to master all their aspects and prepares you to dig deeply into the many fascinating questions of their origin, relationships to earth history and practical uses. Key topics include the production of mud, its transport, the important role of bottom oxygen, sites of deposition, burial, provenance, mudstones in basins and an overview of practical uses followed by an appendix and extended glossary.

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Moving Wearables into the Mainstream : Taming the Borg

Moving Wearables into the Mainstream also introduces concepts such as Operational Inertia that form a mindset conducive to designing wearables suitable for broad adoption by consumers. This book provides insight into legal and cultural issues potentially unfamiliar to research engineers, as well as a broad discussion of technologies underlying wearable devices.Moving Wearables into the Mainstream is designed for a professional audience of practitioners and researchers in industry. This volume is also suitable as a secondary advanced-level text or reference book for students in computer science and electrical engineering.

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Motivational profiles in TIMSS mathematics : Exploring student clusters across aountries and time

This open access book presents a person-centered exploration of student profiles, using variables related to motivation to do school mathematics derived from the IEA’s Trends in International Mathematics and Science Study (TIMSS) data. Statistical cluster analysis is used to identify groups of students with similar motivational profiles, across grades and over time, for multiple participating countries. In this book, a person-centered analysis of distinct and meaningful motivational profiles and their differences on sociodemographic variables and mathematics performance broadens understanding about the role that motivation characteristics play in learning and achievement in mathematics.

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More Joel on software : Further toughts on diverse and occasionally related matters that will prove of interest to software developers, designers, and managers, and to those who, whether by good fortune or III Luck, work with them in some capacity

Joel Spolsky started his weblog in March 2000 in order to offer his insights, based on years of experience, on how to improve the world of programming. This weblog has become infamous among the programming world, and is linked to more than 600 other web sites and translated into 30+ languages! Spolsky's extraordinary writing skills, technical knowledge, and caustic wit have made him a programming guru. With the success of Joel on Software, there has been a strong demand for additional gems and advice, and this book is the answer to those requests. Containing a collection of all–new articles from the original, More Joel on Software has even more of an edge than the original, and the tips for running a business or managing people have far broader application than the software industry.

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Moral Psychology Today : Essays on Values, Rational Choice, and the Will

This book brings together in one volume some of the very latest developments in moral psychology that were presented at a major American conference in 2004. Moral psychology is a broad area at the intersection of moral philosophy and philosophy of mind and action. Essays in this collection deal with most of the central issues in moral psychology that are of interest to a large number of philosophers today, including important questions in normative ethical theory, meta-ethics, and applied ethics.

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Mono-Cycle Photonics and Optical Scanning Tunneling Microscopy : Route to Femtosecond Ångstrom Technology

"Mono-Cycle Photonics and Optical Scanning Tunneling Microscopy" deals with both the ultrashort laser-pulse technology in the few- to mono-cycle region and the laser-surface-controlled scanning-tunneling microscopy (STM) extending into the spatiotemporal extreme technology. The former covers the theory of nonlinear pulse propagation beyond the slowly-varing-envelope approximation, the generation and active chirp compensation of ultrabroadband optical pulses, the amplitude and phase characterization of few- to mono-cycle pulses, and the feedback field control for the mono-cycle-like pulse generation. In addition, the wavelength-multiplex shaping of ultrabroadband pulse is described. The latter covers the CW-laser-excitation STM, the femtosecond-time-resolved STM and atomic-level surface phenomena controlled by femtosecond pulses.

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Monoaminergic modulation of cortical excitability

Monoaminergic Modulation of Cortical Excitability serves as an integrative and comprehensive comparison of the diverse and complex modulatory action of dopamine, noradrenaline, and serotonin receptors in the cortex. The volume is organized into several sections offering a broad spectrum of opinions on how the monoamine systems affect cortical function from a cellular/sub-cellular level to a system level. The complexity of these interactions are discussed in light of recent data showing how disruption of these systems dramatically affects the memory formation and information processing in the cortex.

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Money, Banking, and Financial Markets : A Modern Introduction to Macroeconomics

Introduction to money, banking, and financial markets, with a special emphasis on the importance of confidence and trust in the macroeconomic system. It also presents the theory of endogenous money creation, in contrast to the standard money multiplier and fractional reserve explanation found in other textbooks. The U.S. economy and financial institutions are used to explain the theoretical and practical framework, with international examples weaved in throughout the text. It covers key topics including monetary policy, fiscal policy, accounting principles, credit creation, central banks, and government treasuries. Additionally, the book considers the international economy, including exchange rates, the Eurozone, Chinese monetary policy, and reserve currencies. Taking a broad look at the financial system, it also looks at banking regulation, cryptocurrencies, real estate, and the oil and gold commodity markets. Students are supported with chapter objectives, key terms, and problems.

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Molecular Biology of Human Cancers: An Advanced Student's Textbook

Presents many of the molecules and mechanisms generally important in human cancers. Following an overview on the cancer problem, individual chapters deal with cancer genetics and epigenetics, DNA damage and repair, oncogenes, tumor suppressors, regulatory pathways in cancer, apoptosis, cellular senescence, tumor invasion, and metastasis. A consensus is emerging that while these common mechanisms and molecules are all relevant to human cancers, in each cancer type (or even subtype) a selection of them are extremely important. For selected cancers, the route from genetic and epigenetic changes to their biological and clinical behavior can already be traced. Part II of the book presents a broad, but exemplary selection of cancers that serve as paradigms to illustrate this point. In fact, cancer research has now reached a critical stage, in which the accumulated knowledge on molecular mechanisms is gradually translated into improved prevention, diagnosis, and treatment. The state, pitfalls, and potential of these efforts are summarized in Part III. More than ever, cancer research is now an interdisciplinary effort which requires a basic knowledge of commonly used terms, facts, issues, and concepts. The aim of this book is to provide advanced students and practitioners of different disciplines with this basis, bridging the gap between standard textbooks of molecular biology, pathology, and oncology on the one hand and the specialized cancer literature on the other.

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Molecular Basis of Symbiosis

Symbiotic associations involving prokaryotes occur ubiquitously and are ecologically highly significant. In symbiotic associations, co-evolution of the partner organisms has led to specific mechanisms of signal exchange and reciprocal regulation, and resulted in novel physiological capabilities of the association as compared to those of the individual partners. Symbiosis research has recently entered an exciting era because molecular biology techniques are available for studying partner organisms in association and in a culture-independent manner. It is the goal of this book to contribute towards a broader perspective and an understanding of the function of symbiotic systems. 14 different model systems have been chosen, comprising well known symbioses as well as novel experimental systems which have only recently become amenable to experimental manipulation.

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Molecular and Cellular Signaling

A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determine what kinds of cells are made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular and cellular signaling in biological systems with an emphasis on the underlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadening their understanding of how cells regulate and coordinate their core activities and how diseases arise when these regulatory systems malfunction, as well as those in chemistry, physics and computer science interested in pursuing careers in biological and medical physics, bioinformatics and systems biology. To that end, the book includes background information and review sections, and chapters on signaling in the immune, endocrine (hormonal) and nervous systems. It has chapters on cancer, apoptosis and gene regulation, and contains chapters on bacteria and viruses. In those chapters not specifically devoted to pathogens, connections between diseases, drugs and signaling are made. Each chapter also features a problem set to facilitate further discussion and understanding.

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Modern Trends in Pseudo-Differential Operators

The ISAAC Group in Pseudo-diferential Operators (IGPDO) was formed at the Fourth ISAAC Congress held at York University in Toronto in 2003 and the Frst volume entitled Advances in Pseudo-di?erential Operators and devoted to papers focussing on pseudo-di?erential operators and its diverse applications was then initiated and published in Professor Israel Gohberg’s series Operator Theory: - vances and Applications in 2004.The vision is to seek new directionsfor the broadsubjectonpseudo-diferentialoperatorsand the strategy is to devote the Catania Volume not only to papers based on lectures given at the special session on pseudo-diferential operators, but also invited - pers that bear on the themes of IGPDO.

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Modern Operative Dentistry : Principles for Clinical Practice

Provides the theoretical knowledge required by students when learning how to diagnose oral diseases, plan treatment, and perform various types of dental restoration. It is also useful for clinicians wishing to update their treatment skills and broaden their understanding operative dentistry. Adopting an evidence-based approach, and in accordance with the philosophy of minimally invasive dentistry, it explains in detail the use of both classic and new restorative materials in various clinical situations. It also discusses the principles of smile analysis, as well the technique for esthetic composite restorations on posterior and anterior teeth, including direct and indirect veneers.

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Modern Multivariate Statistical Techniques : Regression, Classification, and Manifold Learning

Remarkable advances in computation and data storage and the ready availability of huge data sets have been the keys to the growth of the new disciplines of data mining and machine learning, while the enormous success of the Human Genome Project has opened up the field of bioinformatics. These exciting developments, which led to the introduction of many innovative statistical tools for high-dimensional data analysis, are described here in detail. The author takes a broad perspective; for the first time in a book on multivariate analysis, nonlinear methods are discussed in detail as well as linear methods.

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Modern Meteor Science : An Interdisciplinary View

"During the past half century meteor research has evolved into a comprehensive multidisciplinary science … . New findings are flowing from the ever-broadening range of investigative techniques that are being employed to great effect by the contributors to this book. This comprehensive overview of leading edge research by well over one hundred authors is an essential resource volume for scientists and engineers conducting studies and exploration of the solar system. It demands a place in the libraries supporting their activities.

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Modern Magnetic Resonance ; Part 1 : Applications in Chemistry, Biological and Marine Sciences ; Part 2 : Applications in Medical and Pharmaceutical Sciences ; Part 3 : Applications in Materials Science and Food Science

Modern Magnetic Resonance provides a unique and comprehensive resource on up-to-date uses and applications of magnetic resonance techniques in the sciences, including chemistry, biology, materials, food, medicine, pharmaceuticals and marine sciences.The widespread appeal of MMR methods for revealing information at the molecular and microscopic levels is noted and examples are provided from the chemical and other sciences.Until now, there has been no single publication that covers all the areas encompassed by "Modern Magnetic Resonance", by bringing together the various techniques and their applications in many scientific areas, the internationally renowned Editors have created a resource of broad appeal to the scientific community.

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