الصفحة 4
الصفحة 4
High performance computing for drug discovery and biomedicine
Explores the application of high-performance computing (HPC) technologies to computational drug discovery (CDD) and biomedicine. Collects CDD approaches that, together with HPC, can revolutionize and automate drug discovery process, such as knowledge graphs, natural language processing (NLP), Bayesian optimization, automated virtual screening platforms, alchemical free energy workflows, fragment-molecular orbitals (FMO), HPC-adapted molecular dynamic simulation (MD-HPC), and the potential of cloud computing for drug discovery. And delves into computational algorithms and workflows for biomedicine, featuring an HPC framework to assess drug-induced arrhythmic risk, digital patient applications relevant to the clinic, virtual human simulations, cellular and whole-body blood flow modeling for stroke treatments, prediction of the femoral bone strength from CT data, and many more subjects.
Hearing Visions and Seeing Voices : Psychological Aspects of Biblical Concepts and Personalities
This book’s aim is to enrich and deepen our psychological understanding of biblical concepts and personalities. Such understanding is relevant for theology as well as for psychology and psychiatry. It may help theologians to contextualize their discipline by bringing it into contact with contemporary psychological and existential issues and tensions, both at an individual and a societal level. It also encourages psychologists and psychiatrists to develop and refine their vocabularies when they try to comprehend the existential meaning of what is transmitted to them by their clients.
Harmonic Analysis and Applications
John J. Benedetto has had a profound influence not only on the direction of harmonic analysis and its applications, but also on the entire community of people involved in the field. This self-contained volume in honor of John covers a wide range of topics in harmonic analysis and related areas, including weighted-norm inequalities, frame theory, wavelet theory, time-frequency analysis, and sampling theory. The invited chapters pay tribute to John’s many achievements and express an appreciation for both the mathematical and personal inspiration he has given to so many students, coauthors, and colleagues. Although the scope of the book is broad, chapters are clustered by topic to provide authoritative expositions that will be of lasting interest.
Happiness—Concept, Measurement and Promotion
This book defines happiness intuitively and explores several common conceptual mistakes with regard to happiness. It then moves on to address topical issues including, but not limited to, whether money can buy you happiness, why happiness is ultimately the only thing of intrinsic value, and the various factors important for happiness. It also presents a more reliable and interpersonally comparable method for measuring happiness and discusses twelve factors, from A to L, that are crucial for individual happiness: attitude, balance, confidence, dignity, engagement, family/friends, gratitude, health, ideals, joyfulness, kindness and love.
Handhelds in medicine : A practical guide for clinicians
Handheld computers are emerging as the stethoscopes of the twenty-first century, and no clinician should be without! These small, easy-to-use devices are now powerful enough to help clinicians manage information and make medical decisions at the point of care. Here, Drs. Stayer, Reynolds and Ebell, practicing physicians and nationally recognized handheld computing experts, show you how to make the most of a handheld computer in your medical practice. This comprehensive how-to guide targets all levels of handheld computer users from novices to experts. It is designed with easy-to-understand hands-on exercises that walk readers through each new skill presented. For beginners, the first section is devoted to "getting to know your handheld," choosing or upgrading a handheld computer, and the basics of handheld operation. There's also a comprehensive chapter on downloading and installing software. Futher sections delve into different types of medical and nonmedical software, Internet and evidence-based resources for medical handheld computing, and, finally, advanced topics such as designing custom software and going wireless. Even the most advanced user will find a lot to learn in this book.
Handbook of psychodiagnostic testing : Analysis of personality in the psychological report
Since the debut of the original edition, the Handbook of Psychodiagnostic Testing has been an invaluable aid to students and professionals performing psychological assessments. The new Fourth Edition continues in that tradition, taking the reader from client referral to finished report, demonstrating how to synthesize details of personality and pathology into a document that is focused, coherent, and clinically meaningful. As with the previous editions, authors Kellerman and Burry offer a systematic framework for choosing the most relevant material from seemingly overwhelming amounts of test data. Separate chapters offer clear rationales for each component of the report (e.g., cognitive functioning, interpersonal behavior, control mechanisms), and how they relate to one another. Helpful summaries follow each chapter, and tables and charts provide salient facts and findings at a glance.
Handbook of Homework Assignments in Psychotherapy : Research, Practice, and Prevention
The Handbook of Homework in Psychotherapy is the first resource for the practicing clinician that addresses the role of homework across major therapeutic paradigms and complex clinical problems. It opens with a series of practice-orientated chapters on the role of homework in different psychotherapies (acceptance and commitment, client-centered, constructivist, cognitive-behavioral, experiential, family, interpersonal, psychodynamic) written by an international team of expert psychotherapy practitioner-researchers. Then, experienced practitioners present strategies, examples, and formulated assignments for use with different populations (couples, families, older adults) and complex problems (chronic depression, chronic pain, eating disorders, obsessions and compulsions, personality disorders, psychosis, sexual dysfunction, substance abuse, traumatic brain injury). The Handbook closes with three chapters by leading psychotherapy theoreticians, researchers, and practitioners that critique the available research evidence for homework, integrate the recommendations for using homework in practice, and also provide directions for homework's role in prevention.
Handbook of genetic diagnostic technologies in reproductive medicine : Improving patient success rates and infant health
Different genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to the clinic, aiming to improve outcomes in the clinic and result in a healthy baby in the home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus.
Guide to software systems development : Connecting novel theory and current practice
This book argues that the key problems of software systems development (SSD) are socio-technical rather than purely technical in nature. Software systems are unique. They are the only human artefacts that are both intangible and determinant. This presents unprecedented problems for the development process both in determining what is required and how it is developed. Primarily this is a problem of communications between stakeholders and developers, and of communications within the development team. Current solutions are not only inadequate in expressing the technical problem, they also evade the communications problems almost entirely.
Guanxi and Business Strategy : Theory and Implications for Multinational Companies in China
Guanxi and Business Strategy" elaborates upon a topic of paramount importance to both academic scholars and managers doing business with China: the impact of personal relationships (guanxi) on business affairs. In the Chinese cultural and socio-economic environment, how are the ubiquitous practices of guanxi to be considered in entrepreneurial strategies,Rather than explaining the emergence of guanxi and its persistence – in spite of the existence of a market economy – with Confucianism, the author applies the phenomenon to the methodology of New Economic Sociology. By integrating guanxi into a business context, he shows that the commercial utilization of guanxi with suppliers, customers, competitors and authorities yields significant sustainable competitive advantages.
Global Conflict Resolution Through Positioning Analysis
Positioning analysis penetrates beneath surface issues to their underlying psychological causes and social effects, with the intention of defusing conflict and preventing existing conflict from escalating. As the growing literature shows, positioning analysis methods are not only effective in interpersonal and intergroup problems, but have considerable potential for resolving disputes on the world stage. Global Conflict Resolution through Positioning Analysis starts with the daily disputes that result from our multiple social identities and evolving self-definitions, offers a new framework for understanding historical conflict, and brings vital new perspectives to current political and ideological battles. Twenty expert contributors examine scenarios as simple as a committee meeting of four people, as complicated as centuries-old social movements and the shifting tensions in the Middle East.
Geschichte des Husserl-Archivs Leuven History
This short History of the Husserl-Archives offers a fascinating view on the foundation and development of this important research institute and of the Husserliana edition. Father Van Breda’s personal annotations, which are made public for the first time in English here, paint a captivating picture of the rescue of Husserl’s manuscripts and the foundation of the Archives shortly before the second world war. The overview of the further history of the Archives by Thomas Vongehr concentrates on the history of the editorial work and its reception. These two texts present not only a historical account but explain the scientific goals and tasks of the Husserl-Archives and its research.
Geospatial Services and Applications for the Internet
This book covers a wide spectrum of techniques, algorithms and modeling methodologies that address the challenges in service-oriented architectural design for GIS, and intelligent processing for spatial queries. This book presents in-depth studies on performance improvement, data integration, service personalization and interoperation between geospatial services. These studies provide the reader with a wide spectrum of examples and case studies on the development of GIS for hydrological applications, electrical power supply applications, land usage and urban planning, and NASA’s Earth image datasets dissemination.
Genetic basis of oral health conditions
This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. The information provided in this book will assist in the delivery of effective personalized dental care through optimization of preventive strategies.
Genes on the Menu : Facts for Knowledge-Based Decisions
Only little more than a decade ago the term "genetic engineering" was hardly known outside research laboratories. Today it regularly makes headlines in the news. Supporters and opponents as well tell us that it could change our lives more than any other technological advance. This book delivers the state-of-the-art facts in order to empower the public to make knowledge-based decisions about plant biotechnology and GM crops and GM food, in particular. It discusses the hot topics of the present debate in a neutral manner and will function as a personal reference book for the interested public, for decision maker, and managers of consumer organisations.
Gathering Hopewell : Society, Ritual and Ritual Interaction
In this book, twenty-one researchers in interwoven efforts immerse themselves and the reader in this vibrant archaeological record in order to richly reconstruct the faces, actions, and motivations Hopewellian people in their social and ritual life. Using a personalized and locally contextualized approach, the authors explore Hopewellian leadership, systems of social ranking and prestige, animal-totemic clan organization, kinship structures, sodalities, gender, community organizations, strategies of intercommunity alliance, and interregional travels for power questing, pilgrimage, healing, tutelage, and acquiring rituals.
Galaxy Formation and Evolution
An Astronomical Life – Observing the Depths of the Universe” Though science as a subject can be di?cult, what has been more important for me is that its practice can also be rewarding fun! This book is crafted to expose the reader to the excitement of modern observational cosmology through the study of galaxy evolution over space and cosmic time. Recent extragalactic research has led to many rapid advances in the ?eld. Even a suitable skeptic of certain pronouncements about the age and structure of the Universe should be pleased with the large steps that have been taken in furthering our understanding of the Universe since the early 1990’s. My personal involvement in galaxy research goes back to the 1960’s. At that point, galaxies were easily recognized and partially understood as organized c- lections of stars and gas. What their masses were presented a problem, which I supposed would just fade away. But fade it didn’t. Distant active nuclei and quasars were discovered in the mid-1960’s. A c- mon view of QSOs was that they have large redshifts, but what use are they for cosmology or normal galaxy astrophysics? I shared that conclusion. My expec- tions fell below their potential utility. In short, the Universe of our expectations rarely matches the Universe as it is discovered.
Future approaches for safe and effective pain management
Pain is defined as an unpleasant sensory and emotional experience that is associated with actual or potential tissue damage or described in terms of such damage. It is subjective and considered an important physiological mechanism by which humans prevent themselves from developing tissue injury. However, pain patients do not respond to treatment in the same way, which makes it challenging to issue a consistent treatment for all pain conditions. Excessive pain can markedly increase psychological health problems and decrease health‐related quality of life; therefore, pain should be managed appropriately by analgesics. Analgesics act in various ways on the peripheral and central pain pathways and are regarded as one of the most valuable but equally dangerous groups of medications. Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. Pain severities as well as responses to analgesics, can also be very variable among sufferer.
Fundamentals of Clinical Data Science
This book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare.
From Principles of Learning to Strategies for Instruction : Empirically Based Ingredients to Guide Instructional Development
The current volume strikes a nice balance between theory and practice and provides a straightforward model of instruction that is easily connected with relevant research but equally easy to apply to instructional development projects… The detailed treatment of the interpersonal domain and the emphasis on technology integration clearly distinguish the book as a modern treatment of instructional development that goes well beyond traditional instructional system development models… Therefore, this volume should provide a well-grounded and useful tool for instructional developers.
