الصفحة 4
الصفحة 4
Imaging of Parasitic Diseases
This book provides an overview of the imaging findings of parasitic diseases using modern imaging equipment. The chapters consist of short descriptions of causative pathogens, epidemiology, modes of transmission, pathology, clinical manifestations, laboratory tests, and imaging findings.
I disturbi della consapevolezza nelle malattie neuropsichiatriche = Disturbances of awareness in neuropsychiatric diseases
Aims to outline the set of current international knowledge on disease awareness in various neuropsychiatric conditions (hemiplegia resulting from brain damage, psychosis, dementia and mood disorders), with particular reference to anosognosia and 'insight. The comparison between different conceptualizations and the variety of clinical manifestations gives rise to a very complex picture that requires a multidimensional approach, especially as regards the diagnostic moment. To this end, the authors propose an integration of various contributions on the pathogenetic level, based on neuroanatomical evidence and supported by the most recent neuroimaging techniques. In addition, the use of a complex diagnostic battery is suggested, capable of analyzing the different aspects of the phenomenon, and distinguishing it from the psychological defensive mechanism of denial. Research in this field is also essential to promote rehabilitation and compliance with treatment, as well as the enrichment of knowledge on the processes underlying consciousness and awareness in the human being.
Hydrogenosomes and Mitosomes : Mitochondria of Anaerobic Eukaryotes
"Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes" provides a summary of the current knowledge of these organelles, which occur in unicellular, often parasitic organisms, including human pathogens. The distribution of these organelles is broad, but they were detected primarily in an anoxic habitat or nutrient rich intracellular niche that permits life without the efficient energy generating system of typical mitochondria. Their common characteristic is that they lack the aerobic energy conservation system of typical mitochondria and that they are usually the site of the synthesis of iron-sulfur clusters, regarded as the only indispensable function of eukaryotic mitochondria.These mitochondria-related organelles exhibit a variety of structures and functions. This work describes properties such as protein import, structure, metabolism, adaptation, proteome and their role in drug activation and resistance. Further topics include the evolution and biogenesis of these organelles.
Human fungal diseases : Diagnostics, pathogenesis, drug resistance and therapeutics
Reviews the latest advancements in the fungal infections and their impact on human health. It presents epidemiology, diagnosis, pathogenesis, risk factors, virulence mechanisms, treatment, and strategies for the disease management and prevention of fungal infections. The book further reviews host-pathogen interactions, biofilm formation, and quorum sensing. It also covers the clinical manifestations, diagnostic approaches, and management strategies of opportunistic fungal infections, emerging fungal infections, and allergic fungal infections. It presents the latest advancements in diagnostic methods and therapeutic strategies, covering both conventional techniques and state-of-the-art approaches. Further, the book elucidates antifungal stewardship, nanotechnology, and omics technologies, providing insights into cutting-edge strategies for prevention, control, and management of multidrug-resistant fungi. This book is useful for researchers, students, and health professionals working in the fields of mycology, infectious diseases, immunology, dermatology, and pulmonology.
Human and Animal Relationships
Pathogenic fungi are widely distributed and can infect many organisms, particularly humans, but also other vertebrates and insects. Due to a growing number of fungal infections, there is an increasing need to understand the interaction of pathogenic fungi with their hosts. This second completely updated and revised edition of Volume VI of The Mycota consists of state of the art reviews written by experts in the field, covering three major areas of this rapidly developing field. In the first part the current understanding of pathogenic fungi and the physiological reactions relevant for the pathogen - host interaction are elucidated. The second part describes novel technologies for the identification of proteins, virulence factors and mechanisms central to the host - pathogen interaction. The third part deals with the characterization of the host response towards pathogenic fungi and addresses timely clinical aspects.
Hugo and Russell's pharmaceutical microbiology
Microbiology is one of the essential pharmaceutical sciences upon which the study and practice of pharmacy is built. It has a bearing on all aspects of the manufacture of medicines and sterile products, from their design and development to their delivery as quality products. Few interventions are more central to modern medicine than the treatment of infection, where antibiosis, vaccination and hygienic practices have essential roles to play. The COVID-19 pandemic, the appearance of new pathogens and the rise of antibiotic resistance have demonstrated most completely the need for pharmaceutical practitioners, researchers and industrial scientists to be fully conversant with this field. The 9th edition of Hugo and Russell’s Pharmaceutical Microbiology has been updated to meet this need. Having long served as the sole comprehensive textbook covering this subject, it has now been adapted to a critical new period in the advancement of medical and pharmaceutical research and development. Its experienced editors have incorporated contributions from subject experts and created a text which will serve the next generation of pharmacy students, pharmaceutical industry scientists and researchers.
How the immune system recognizes self and nonself : Immunoreceptors and their signaling
This brain function must have been particularly important for most animals to protect their lives from enemies and for species to survive through evolution. Similarly, higher organisms have also acquired their immune system through evolution that discriminates nonself pathogens and self-body to protect their lives from pathogens such as bacteria or viruses. The brain system may distinguish integrated images of self and nonself created from many inputs, such as vision, sound, smell, and others. The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything but self.
Host-pathogen interactions : Methods and protocols
Serves as multidisciplinary compendium of approaches and techniques employed to analyze the role of different molecules, processes, or strategies used by different guests to survive and proliferate in their associations with eukaryotic hosts. Beginning with animal-pathogen interactions, the book then continues with chapters exploring virus-host interactions, plant-microbe interactions, as well as different molecular techniques that were initially applied to non-pathogenic interactions but can be adapted to study other host-pathogen associations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips for troubleshooting and avoiding known pitfalls.
Hormones and the brain
Peripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behaviour and aging. Depending upon intensity and duration of exposure, they can be either neuroprotective or neurotoxic, for instance by affecting production of free radicals. This book, based on contributions of pioneer investigators in the field, outlines the ambiguous actions of gonadal steroids (estradiol, progesterone, testosterone, inhibin and activin) and of neurosteroids, related moieties produced in the brain itself. After summarizing their multiple mechanisms of action, which involve both direct effects on neuronal membranes and activation of genes coding for specific proteins in neurons or glial cells, the book outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.
Hodgkins and Non-Hodgkins Lymphoma
In this volume, an internationally recognized group of experts provides a comprehensive overview of the biology, pathology, standard treatments, and novel approaches in management of patients across the complex landscape of lymphoma subtypes.
Hidradenitis Suppurativa
This is the first and most comprehensive book perts to give their opinion and interpretation of dedicated to the understanding and treatment the disease, and left our own point of view to the of hidradenitis suppurativa. The most recent chapters summarizing pathogenesis and the- monograph on this disease was Dr Benedek’s py. At points you may therefore find discussions supplement to Acta Dermatovenerologica in of e. g.
Herbal antibiotics : Natural alternatives for treating drug-resistant bacteria ; 2nd ed.
Health care providers have discovered many new resistant strains of bacteria, researchers have added to the growing body of knowledge about herbs, and the need for antivirals to treat emerging infections like SARS and West Nile Encephalitis has become urgent. Within ten years, according to sources cited in the book, pharmaceutical antibiotics will begin to fail at epidemic rates. There are, in fact, no new antibiotics currently in planning or development at any of the major pharmaceutical companies. Most notably, there is none for Gram-negative bacteria, which are emerging as the most dangerous pathogens.
Hepatitis C Virus Disease
Emphasizes the most recent advances on the Hepatitis C virus infection (HCV) moving from basic research to clinical application. In spite of the numerous studies on HCV infection, its pathogenesis and medical treatment have not been fully explained. The first chapters of this volume analyize the full spectrum of immune responses to HCV taking into account either innate or adoptive immunity involvement. The volume also includes a series of contributions which explain the state of art of IFN-alpha treatment in HCV patients and the effectiveness of therapy also in relation to HCV genotypes. The use and applications of pegylated IFNs will also be discussed as well as the complicated HCV disease and its treatment. Hepatitis C Virus Disease: Immunobiology and Clinical Applications is an ideal volume for researchers, scientists, professionals, clinicians, physicians and graduate students in the fields of infectious disease, immunology, virology, microbiology, pharmacology and medicine.
Hematologic Malignancies : Acute Leukemias
Several chapters in this volume describe current knowledge of acute leukemia biology and discuss new classification systems that have arisen consequent to emerging insights into pathogenesis. Treatment has also improved for particular types of acute leukemia.
Heat Shock Proteins and the Brain : Implications for Neurodegenerative Diseases and Neuroprotection
Neurodegenerative disorders such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and amyotrophic lateral sclerosis have been termed ‘protein misfolding disorders’ that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV).
Handbook of Renal Biopsy Pathology
This practical handbook provides a short, clear and useful guide to interpretation of renal biopsy specimens. It is intended to be useful to pathologists, pathologists-in-training, nephrologists, nephrologists-in-training and medical students.
Handbook of Pathogens and Diseases in Cephalopods
The aim of this book is to facilitate the identification and description of the different organs as well as pathogens and diseases affecting the most representative species of cephalopods focussed on Sepia officinalis, Loligo vulgaris and Octopus vulgaris. These species are valuable ‘morphotype’ models and belong to the taxonomic groups Sepioidea, Myopsida and Octopoda, which include most of the species with a high market value and aquaculture potential. The study is based on photographs at macroscopic and histological level in order to illustrate the role of the most important pathogens and related diseases from the view of a pathological diagnosis. The reader is able to familiarize with functional anatomy, necropsy and general histology of adults and paralarvae, as well as with the identification of different pathogens and pathologies. This work is thus an invaluable guide for the diagnosis of cephalopod diseases. Besides including pathogens for non-European cephalopod species, it also provides a useful contribution encouraging marine pathologists, parasitologists, veterinarians and those involved in fishery sanitary assessments, aquarium maintenance and aquaculture practices aiming to increase their knowledge about the pathology of cephalopods.
Handbook of nutrition and ophthalmology
The Handbook of Nutrition in Ophthalmology is the first general text on nutrition and eye health created for physicians, nutritionists, and researchers. Dr. Richard D. Semba provides important links between the epidemic of obesity and implications it has for eye disease and blindness. The volume addresses three broad themes throughout. The first is that a healthy diet as a major lifelong habit will likely have an impact on reducing a substantial portion of visual impairment and blindness. The second is that a historical perspective is essential to understanding current challenges in ophthalmology, medicine, and public health. The third theme is that many nutrients play a role in oxidative stress and inflammation, and this theory has emerged as a major underlying hypothesis in the pathogenesis of eye diseases.
Handbook of neurochemistry and molecular neurobiology : Neuroimmunology
Neuroimmunology is one of the most rapidly developing branches of Neurobiology, and this volume contains chapters that focus on a huge range of topics including the relationship between neuroimmunology and the pathogenesis of different nervous diseases.
Handbook of cardiovascular behavioral medicine
Cardiovascular disease is the leading cause of morbidity and mortality in the United States and worldwide. It is well recognized that traditional risk factors for cardiovascular disease have limited predictive utility in the identification of new cardiovascular disease cases and outcomes. Thus, investigators have argued that application of a biopsychosocial research paradigm in this field may be of particular utility in understanding cardiovascular disease pathogenesis. Accordingly, a subdiscipline within the field of behavioral medicine – cardiovascular behavioral medicine – examines interrelations among biological, behavioral, psychological, social, and environmental factors in cardiovascular health and disease.
