الصفحة 4
الصفحة 4
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Molecular Marker Systems in Plant Breeding and Crop Improvement

Successful release of new and better crop varieties increasingly requires genomics and molecular biology. This volume presents basic information on plant molecular marker techniques from marker location up to gene cloning. The text includes a description of technical approaches in genome analysis such as comparison of marker systems, positional cloning, and array techniques in 19 crop plants. A special section focuses on converting this knowledge into general and specific breeding strategies, particularly in relation to biotic stress. Theory and practice of marker assisted selection for QTL, gene pyramiding and the future of MAS are summarized and discussed for maize, wheat, and soybean. Furthermore, approaches in silviculture on the examples of Fagus, Populus, Eucalyptus, Picea and Abies are presented. The volume ends with a comprehensive review of the patents relevant for using molecular markers and marker assisted selection.

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Molecular genetics, structures, mechanisms, and functions : Principles of gene manipulation and genomics ; Vol.1

Provides an overview of the future of genetic engineering and delves into the role of biotechnology and its applications in genetic engineering. It discusses the tools of recombinant technology, which have brought about revolution in our understanding of various complex biological phenomena. Chapters cover mutagenesis, construction, and sequencing of DNA libraries along with applications of genetic engineering for improving health, preventing genetic diseases, enhancing food resources, managing environmental bioremediation, and more. Topics include genetic engineering tools for restriction enzymes and vectors, gene and cell division, mutation detection and screening in plants, population genetics, sexuality in bacteria, and more. Several chapters focus on the tools of recombinant technology, such as restriction enzymes, vectors, etc., that have paved the way for creating organisms of choice and opened new horizons in the field of medicine, agriculture, and industry for human welfare.

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Molecular Diagnostic PCR Handbook

PREFACE The Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture is involved in agricultural research and development and assists Member States of FAO and IAEA in improving strategies to ensure food security through the use of nuclear techniques and related biotechnologies, where such techniques have a valuable and often unique role. In particular, molecular diagnostic methods have rapidly evolved in the past twenty years, since the advent of the Polymerase Chain Reaction (PCR). They are used in a wide range of agricultural areas such as, improving soil and water management; producing better crop varieties; diagnosing plant and animal diseases; controlling insect pests and improving food quality and safety. The uses of nucleic acid-directed methods have increased significantly in the past five years and have made important contributions to disease control country programmes for improving national and international trade. These developments include the more routine use of PCR as a diagnostic tool in veterinary diagnostic laboratories. However, there are many problems associated with the transfer and particularly, the application of this technology. These include lack of consideration of: the establishment of quality-assured procedures, the required set-up of the laboratory and the proper training of staff. This can lead to a situation where results are not assured. This book gives a comprehensive account of the practical aspects of PCR and strong consideration is given to ensure its optimal use in a laboratory environment. This includes the setting-up of a PCR laboratory; Good Laboratory Practice and standardised of PCR protocols.

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Molecular Biology in Plant Pathogenesis and Disease Management : Microbial Plant Pathogens ; Vol.1

Studies on molecular biology of pathogens, infection process and disease resistance, have provided information essentially required to understand the vulnerable stages at which the pathogens can be tackled effectively and to adopt novel strategies to incorporate disease resistance genes from diverse sources and /or to induce resistance of cultivars with desirable agronomic attributes using biotic or abiotic agents. The nature of interaction between the gene products of the pathogen and plant appears to determine the outcome of the interaction resulting in either disease progression or suppression. Transgenic plants with engineered genes show promise for effective exploitation of this approach for practical application. Research efforts during the recent years to sequence the whole genomes of the pathogens and plants may lead to development of better ways of manipulating disease resistance mechanisms enabling the grower to achieve higher production levels and the consumer to enjoy safer food and agricultural products. Experimental protocols included in appropriate chapters will be useful for researchers and graduate students.

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Molecular Biology in Plant Pathogenesis and Disease Management : Disease Management ; Vol.3

Exclusion and eradication of plant pathogens by rapid and precise detection and identification of microbial pathogens in symptomatic and asymptomatic plants and planting materials by employing molecular methods has been practiced extensively by quarantines and certification programs with a decisive advantage. Identification of sources of resistance genes, cloning and characterization of desired resistance genes and incorporation of resistance gene(s) into cultivars and transformation of plants with selected gene(s) have been successfully performed by applying appropriate molecular techniques. Induction of resistance in susceptible cultivars by using biotic and abiotic inducers of resistance is a practical proposition for several crops whose resistance levels could not be improved by breeding or transformation procedures. The risks of emergence of pathogen strains less sensitive or resistant to chemicals have been reduced appreciably by rapid identification of resistant strains and monitoring the occurrence of such strains in different geographical locations.

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Molecular Basis of Thyroid Cancer

Molecular Basis of thyroid Cancer brings together top-flight experts from across the globe to consider present state of the art treatment and techniques and what the future holds. The product of this effort is invaluable to endocrinologists, particularly those with an interest in the thyroid, molecular oncologists, nuclear medicine physicians and those in biotechnology intent on devising innovative therapies for cancer. "Significant advances in our understanding of thyroid cancer have occurred over the previous decade. This text discusses the molecular alterations and pathologic manifestations seen in this disease. Distinguished investigators address both the basic biology and clinical issues pertinent to our understanding and management of patients with thyroid cancer."

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Molecular Basis of Symbiosis

Symbiotic associations involving prokaryotes occur ubiquitously and are ecologically highly significant. In symbiotic associations, co-evolution of the partner organisms has led to specific mechanisms of signal exchange and reciprocal regulation, and resulted in novel physiological capabilities of the association as compared to those of the individual partners. Symbiosis research has recently entered an exciting era because molecular biology techniques are available for studying partner organisms in association and in a culture-independent manner. It is the goal of this book to contribute towards a broader perspective and an understanding of the function of symbiotic systems. 14 different model systems have been chosen, comprising well known symbioses as well as novel experimental systems which have only recently become amenable to experimental manipulation.

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Modulation of host gene expression and innate immunity by viruses

This book is reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases.

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Modernisation, Mechanisation and Industrialisation of Concrete Structures

Modernisation, Mechanisation and Industrialisation of Concrete Structures discusses the manufacture of high quality prefabricated concrete construction components, and how that can be achieved through the application of developments in concrete technology, information modelling and best practice in design and manufacturing techniques.

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Modern socio-technical perspectives on privacy

This book provides researchers and professionals with a foundational understanding of online privacy as well as insight into the socio-technical privacy issues that are most pertinent to modern information systems, covering several modern topics (e.g., privacy in social media, IoT) and underexplored areas (e.g., privacy accessibility, privacy for vulnerable populations, cross-cultural privacy).

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Modern IoT onboarding platforms for advanced applications: a practitioner’s guide to KIS.ME

There is no doubt that digitalization solutions from Industry 4.0 and the Internet of Things (IoT) can be perceived as excellent candidate strategies capable of handling the above-stated issues concerning measurements and transparency. However, IoT tools themselves can provide appropriate data only, while their efficient integration and application are possible using a dedicated onboarding platform only. To settle this issue, the book undertakes the problem of modern IoT onboarding platforms for the advanced applications pertaining to manufacturing and logistics. In particular, instead of deliberating about a possible hypothetic platforms, an existing and efficient one is employed, which is called KIS.ME. KIS.ME (Keep It Simple. Manage Everything) is a complete IoT solution for a simple integration in manufacturing and logistics.

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Modern aspects of pharmaceutical quality assurance : developing and proposing application models, SOPs, practical audit systems for pharma industry

Aims to develop a tool that will substantially decrease the number of Inspectional Observations and Warning letters, thus eliminating Import Alerts and Consent Decree. This book targets the Pharmaceutical Industry and students of Pharmaceutical Quality Assurance so they can get in hand-ready consolidated information on Pharmaceutical Quality guidelines, Quality metrics, and implementation of simplified SOP guidelines, plant layouts to implement Quality metrics for Pharmaceutical Manufacturing systems in tablets, capsules, liquid orals, and semi-solid dosage forms.

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Models, Methods and Tools for Product Service Design : The Manutelligence Project

This book summarizes research being pursued within the Manutelligence project, the goal of which is to help enterprises develop smart, social and flexible products with high value added services. Manutelligence has improved Product and Service Design by developing suitable models and methods, and connecting them through a modular, collaborative and secure ICT Platform. The use of real data collected in real time by Internet of Things (IoT) technologies underpins the design of product-service systems and makes it possible to monitor them throughout their life cycle. Available data allows costs and sustainability issues to be more accurately measured and simulated in the form of Life Cycle Cost (LCC) and Life Cycle Assessment (LCA). Analysing data from IoT systems and sharing LCC and LCA information via the ICT Platform can help to accelerate the design of product-service systems, reduce costs and better understand customer needs. Industrial partners involved in Manutelligence provide a clear overview of the project's outcomes, and demonstrate how its technological solutions can be used to improve the design of product-service systems and the management of product-service life cycles.

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Modelling and Optimization of Biotechnological Processes : Artificial Intelligence Approaches

The book begins with a historical introduction to the field of bioprocess control based on artificial intelligence approaches, followed by two chapters covering the optimization of fed-batch culture using genetic algorithms. Online biomass soft-sensors are constructed in Chapter 4 using recurrent neural networks. The bioprocess is then modelled in Chapter 5 by cascading two soft-sensor neural networks. Optimization and validation of the final product are detailed in Chapters 6 and 7. The general conclusions are drawn in Chapter 8.

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Modeling and Control of Antennas and Telescopes

Modeling and Control of Antennas and Telescopes presents the author’s research and field experience in the area of antenna modeling, dynamics, and control. The required spacecraft tracking accuracy of 1 mdeg was the impetus for the new approaches to the antenna controls that use model based controllers (LQG and H¥ ). Consequently, modeling also required a new approach using system identification techniques. Most of the material presented is new in the telescope industry. The methods have been not only analyzed and tested, but actually implemented, giving confidence in the final result, which is significantly increased antenna pointing accuracy.

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Model and Design of Bipolar and MOS Current-Mode Logic : CML, ECL and SCL Digital Circuits

many works and results have been published which reinforce the importance of Current-Mode digital circuits. In the topic of Current-Mode digital circuits, the authors properly exploited classical paradigms developed and used in the analog circuit domain (a topic in which one of the authors maturated a great experience).

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Mobility, data mining and privacy : Geographic knowledge discovery

This book assesses this research frontier from a computer science perspective, investigating the various scientific and technological issues, open problems, and roadmap. The editors manage a research project called GeoPKDD, Geographic Privacy-Aware Knowledge Discovery and Delivery, funded by the EU Commission and involving 40 researchers from 7 countries, and this book tightly integrates and relates their findings in 13 chapters covering all related subjects, including the concepts of movement data and knowledge discovery from movement data; privacy-aware geographic knowledge discovery; wireless network and next-generation mobile technologies; trajectory data models, systems and warehouses; privacy and security aspects of technologies and related regulations; querying, mining and reasoning on spatiotemporal data; and visual analytics methods for movement data.

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Mobile Edge Computing

It offers comprehensive, self-contained knowledge on Mobile Edge Computing (MEC), which is a very promising technology for achieving intelligence in the next-generation wireless communications and computing networks. The book starts with the basic concepts, key techniques and network architectures of MEC. Then, we present the wide applications of MEC, including edge caching, 6G networks, Internet of Vehicles, and UAVs. In the last part, we present new opportunities when MEC meets blockchain, Artificial Intelligence, and distributed machine learning (e.g., federated learning). We also identify the emerging applications of MEC in pandemic, industrial Internet of Things and disaster management.

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Mobile and Wireless Communications with Practical Use-Case Scenarios

While wireless technologies had a spectacular evolution over the past years, the present trend is to adopt a global heterogeneous network of shared standards that enables the provisioning of Quality of Service and Quality of Experience to the end-user. To this end, enabling technologies like Machine Learning, Internet of Things, Digital Twins, are seen as promising solutions for next generation networks that will enable an intelligent adaptive interconnected environment with support for prediction and decision making so that the heterogeneous applications and users requirements can be highly satisfied. The aim of this textbook is to provide the readers with a comprehensive technical foundation of the mobile communication systems and wireless network design, operations and applications of various radio access technologies. Additionally, it also introduces the reader to the latest advancements in technologies in terms of Internet of Things ecosystem, Machine Learning and Digital Twins for IoT-enabled intelligent environments. Furthermore, this textbook also includes practical use-case scenarios using Altair WinProp Software as well as Phyton, TensorFlow and Jupiter as support for practice-based laboratory sessions"

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Minimal English for a Global World : Improved Communication Using Fewer Words

This book introduces a new tool for improving communication and promoting clearer thinking in a world where the use of Global English can create numerous comprehension and communication issues. Based on research findings from cross-linguistic semantics, it contains essays and studies by leading experts exploring the value and application of ‘Minimal English’ in various fields, including ethics, health, human rights discourse, education and international relations.

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