الصفحة 4
الصفحة 4
Nuclear Dynamics : Molecular Biology and Visualization of the Nucleus
The dynamics of nuclear structures described in this book furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.
Nuclear Condensed Matter Physics with Synchrotron : Basic Principles, Methodology and Applications
This book provides a comprehensive introduction to the growing field of nuclear condensed matter physics with synchrotron radiation, a technique which finds numerous applications in fields such as magnetism, physics of surfaces and interfaces, lattice dynamics and more. Due to the enormous brilliance of modern synchrotron radiation sources, the method is particularly suited for the investigation of low-dimensional structures such as thin films and nanoparticles. The use of isotopic probe layers, for example, allows one to determine magnetic and vibrational properties with very high spatial resolution; focusing techniques and x-ray interference effects lead to a very high sensitivity for smallest amounts of material. The book is written on an introductory level with many examples employed to illustrate the special experimental possibilities.
NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders : from Genes to Therapeutics
The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders. The identification of multiple receptors for the members of the NPY and PYY family of peptides provides new opportunities for discovery of specific NPY antagonists and agonists that have vast clinical potential. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists, which are in clinical development for obesity. NPY Y1 receptor antagonists are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders is also actively pursued. The chapters in this book are written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.
Novel mouse model for future autism research
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures in the first 3 years of life. It is not a single disorder, and it is broadly considered to be a multi-factorial disorder resulting from genetic and non-genetic risk factors and their interaction. Genetic studies of ASD have identified mutations that interfere with typical neurodevelopment in utero through childhood. These complexes of genes have been involved in synaptogenesis and axon motility. Recent developments in neuroimaging studies have provided many important insights into the pathological changes that occur in the brain of patients with ASD in vivo. Especially, the role of amygdala, a major component of the limbic system and the affective loop of the cortico-striatothalamo-cortical circuit, in cognition and ASD has been proved in numerous neuropathological and neuroimaging studies.
Novel drug delivery systems : Fundamentals and applications
Serves as a unique resource on the field of novel drug delivery systems (NDDSs). The evolving nature of diseases and the emergence of new health complications have driven a significant shift in drug therapy. Coupled with changes in human lifestyles and economic conditions, these factors have compelled the pharmaceutical industry to develop novel, efficient, and affordable drug products. The rise of promising technologies aimed at enhancing therapeutic performance further underscores the importance of novel drug delivery systems (NDDSs), making this field one of the most dynamic in pharmaceutical sciences today.
Novel Developments for Sustainable Hydropower
This book presents (selected) new and innovative developments for sustainable and fish-friendly hydropower. It offers unique insights into the challenges, practices and policies of hydropower developments across 8 European countries, providing examples from on-site studies and European-wide analyses. The case studies throughout the book are practical “real-world” examples, which are intended to serve as inspiration for anyone who would like to know more about how solutions for more sustainable hydropower production can be designed and implemented. Hydropower is an important renewable energy source, which, however, can also impact aquatic ecosystems, fish populations and hydro-morphology. EU and national water, environmental and energy legislation strive for sustainable energy and water resource management as well as the protection of important habitats and species. These have an effect on the requirements and decision making processes for hydropower planning, commissioning and operation. With a high variety of measures existing and site-specific conditions as well as national and EU level legal requirements to consider, it can be difficult to determine, what issues to address and which measures to implement.
Notch Signaling in Embryology and Cancer : Notch Signaling in Cancer
This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.
Norwegian Shipping in the 20th Century : Norway's Successful Navigation of the World's Most Global Industry
This open access book discusses how Norwegian shipping companies played a crucial role in global shipping markets in the 20th century, at times transporting more than ten per cent of world seaborne trade. Chapters explore how Norway managed to remain competitive, despite being a high labour-cost country in an industry with global competition. Among the features that are emphasised are market developments, business strategies and political decisions The Norwegian experience was shaped by the main breaking points in 20th century world history, such as the two world wars, and by long-term trends, such as globalization and liberalization. The shipping companies introduced technological and organizational innovations to build or maintain a competitive advantage in a rapidly changing world. The growing importance of offshore petroleum exploration in the North Sea from the 1970s was both a threat and an opportunity to the shipping companies. By adapting both business strategies and the political regime to the new circumstances, the Norwegian shipping sector managed to maintain a leading position internationally.
Northern Lights on Civic and Citizenship Education : A Cross-national Comparison of Nordic Data from ICCS
This book presents an in depth analysis of data from ICCS. An international group of scholars critically address the state of civic and citizenship education in the four Nordic countries that participated in the IEA International Civic and Citizenship Education Study (ICCS) in 2009 and 2016. The findings are of particular relevance to educators at all levels, from school education through to teacher education.
Non-Vitamin K Antagonist Oral Anticoagulants : A Concise Guide
An essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.
Non-University Higher Education in Europe
This book represents the first-of-its-kind comprehensive discussion of the non-university higher education sector in Europe. Higher education throughout the world is facing rapid change. Despite the enormous attention devoted to that reality, this volume fills an important void. It describes and offers critical comparisons between the systems in 10 European countries. The book brings together the thinking of leading scholars on the non-university sectors in Austria, Belgium, Finland, Germany, Ireland, the Netherlands, Norway, Portugal, Spain, and the United Kingdom, with a chapter devoted to each country. National case studies are presented for the non-university sector in these countries that address issues such as historical developments, policy changes, governance structures, levels of institutional autonomy and future trends.
Nonparametric Functional Data Analysis : Theory and Practice
Modern apparatuses allow us to collect samples of functional data, mainly curves but also images. On the other hand, nonparametric statistics produces useful tools for standard data exploration. This book links these two fields of modern statistics by explaining how functional data can be studied through parameter-free statistical ideas. This book starts from theoretical foundations including functional nonparametric modeling, description of the mathematical framework, construction of the statistical methods, and statements of their asymptotic behaviors. It proceeds to computational issues including R and S-PLUS routines. Several functional datasets in chemometrics, econometrics, and pattern recognition are used to emphasize the wide scope of nonparametric functional data analysis in applied sciences. The companion Web site includes R and S-PLUS routines, command lines for reproducing examples presented in the book, and the functional datasets. Rather than set application against theory, this book is really an interface of these two features of statistics. A special effort has been made in writing this book to accommodate several levels of reading.
Non-metallic biomaterials for tooth repair and replacement
Focuses on the use of biomaterials for a range of applications in tooth repair and, in particular, dental restoration. Part one reviews the structure, modification and repair of dental tissues. The properties of enamel and dentin and their role in adhesive dental restoration are discussed, along with biomineralization and biomimicry of tooth enamel, and enamel matrix proteins (EMPs) for periodontal regeneration. Part two goes on to discuss the processing, bonding and wear properties of dental ceramics, glasses and sol-gel derived bioactive glass ceramics for tooth repair and replacement. Dental composites for tooth repair and replacement are then the focus of part three, including composite adhesive and antibacterial restorative materials for dental applications. T
Nonlinear Waves : Classical and Quantum Aspects
Leading scientists discuss the most recent physical and experimental results in the physics of Bose-Einstein condensate theory, the theory of nonlinear lattices (including quantum and nonlinear lattices), and nonlinear optics and photonics. Classical and quantum aspects of the dynamics of nonlinear waves are considered. The contributions focus on the Gross-Pitaevskii equation and on the quantum nonlinear Schrödinger equation. Recent experimental results on atomic condensates and hydrogen bonded systems are reviewed. Particular attention is given to nonlinear matter waves in periodic potential.
Nonlinear Time Series Analysis in the Geosciences : Applications in Climatology, Geodynamics and Solar-Terrestrial Physics
This book presents recent developments in nonlinear time series which have been motivated by present day problems in geosciences. Modern methods of spatio-temporal data analysis, time-frequency analysis, dimension analysis, nonlinear correlation and synchronization analysis and other nonlinear concepts are used to study emerging questions in climatology, geophysics, solar-terrestrial physics and related scientific disciplines. This volume collects contributions of some of the world's leading experts in geoscientific time series analysis.
Nonlinear Problems of Elasticity
This second edition is an enlarged, completely updated, and extensively revised version of the authoritative first edition. It is devoted to the detailed study of illuminating specific problems of nonlinear elasticity. The mathematical tools from nonlinear analysis are given self-contained presentations where they are needed. This book begins with chapters on (geometrically exact theories of) strings, rods, and shells, and on the applications of bifurcation theory and the calculus of variations to problems for these bodies. The book continues with chapters on tensors, three-dimensional continuum mechanics, three-dimensional elasticity, large-strain plasticity, general theories of rods and shells, and dynamical problems. Each chapter contains a wealth of interesting, challenging, and tractable exercises.
Nonlinear Partial Differential Equations for Scientists and Engineers
This expanded and revised second edition is a comprehensive and systematic treatment of linear and nonlinear partial differential equations and their varied applications. Building upon the successful material of the first book, this edition contains updated modern examples and applications from areas of fluid dynamics, gas dynamics, plasma physics, nonlinear dynamics, quantum mechanics, nonlinear optics, acoustics, and wave propagation. Methods and properties of solutions are presented, along with their physical significance, making the book more useful for a diverse readership.
Nonlinear Fokker-Planck Equations : Fundamentals and Applications
Providing an introduction to the theory of nonlinear Fokker-Planck equations, this book discusses fundamental properties of transient and stationary solutions, emphasizing the stability analysis of stationary solutions by means of self-consistency equations, linear stability analysis, and Lyapunov's direct method. Also treated are Langevin equations and correlation functions. Nonlinear Fokker-Planck Equations addresses various phenomena such as phase transitions, multistability of systems, synchronization, anomalous diffusion, cut-off solutions, travelling-wave solutions and the emergence of power law solutions. A nonlinear Fokker-Planck perspective to quantum statistics, generalized thermodynamics, and linear nonequilibrium thermodynamics is given. Theoretical concepts are illustrated where possible by simple examples. The book also reviews several applications in the fields of condensed matter physics, the physics of porous media and liquid crystals, accelerator physics, neurophysics, social sciences, population dynamics, and computational physics.
Non-Linear Electromechanics
This is the first book in which problems of electromechanics are considered from the perspective of analytical mechanics. The book includes fundamental results in the theory of non-linear electromechanical systems and will be useful both for researchers, engineers, scholars and graduate students of electromechanical faculties of technical universities. It includes not only theoretical results but also various examples from many industrial applications. A sizeable part of the book is devoted to the general theory of synchronous machines and electro-magnetic exciters of oscillations.
Nonlinear dynamics in complex systems via fractals and fractional calculus
Current advances in the knowledge of nonlinear dynamical networks, systems and processes, as well as their unified repercussions, allow us to include some typical complex natural phenomena, from the nanoscale to an extra-galactic scale, in an unitarian comprehensive manner. In other words, the physical, biological and financial data, as well as technological ones (mechanical or electronic devices), of complex systems available today can be managed by the same unique conceptual approach, both analytically and through a computer simulation, using effective nonlinear dynamics procedures. This volume collected some important advances in the fields of fractal curves, fractal analysis and fractional calculus, as well as new solutions of fractal differential equations.
