Modeling and simulation tools for emerging telecommunication networks : Needs, trends, challenges and solutions
This book contains a selection of papers presented at a symposium organized under the aegis of COST Telecommunications Action 285. The main objective of the Action is to enhance existing tools and develop new modeling and simulation tools for research in emerging multi-service telecommunication networks in the areas of model performance improvements, multilayer traffic modeling, and the important issue of evaluation and validation of the new modeling tools.
Model-Based Engineering of Collaborative Embedded Systems : Extensions of the SPES Methodology
This book presents the results of the "Collaborative Embedded Systems" (CrESt) project, aimed at adapting and complementing the methodology underlying modeling techniques developed to cope with the challenges of the dynamic structures of collaborative embedded systems (CESs) based on the SPES development methodology.
Mobile Virtual Work : A New Paradigm?
This is a book about mobile virtual work. It aims at clarifying the basic concepts and showing present practices and future challenges. With this book we realise our intention to present a ‘state of the art’ collection of knowledge on this subject. We very much hope that you will find the discussion about present day reality and future challenges of mobile virtual work as exciting as we do. It is possibly a new paradigm.
Mobile Phone Programming and its Application to Wireless Networking
This book provides a solid overview of mobile phone programming targeting both academia and industry. Mobile Phone Programming covers all commercial realizations of Symbian, Windows Mobile and Linux platforms. Each programming language (JAVA, Python, C/C++) and a set of development environments are introduced “step by step” making developers familiar with current limitations, pitfalls, and challenges. Each chapter contains examples and source code to rapidly make developers familiar with the most important concepts. Examples cover peer to peer networks, cooperative networking, cross layer protocol design, key challenges such as power consumption, and sensor networks for which a full hardware and software implementation is provided. Whether you are an experienced developer or an advanced student Mobile Phone Programming will be your key reference for successfully entering the world of software development for mobile devices.
Migration to and from Welfare States : Lived Experiences of the Welfare–Migration Nexus in a Globalised World
This book explores the role of family, public, market and third sector welfare provision for individual and households’ decisions regarding geographical mobility. It challenges the state-centred approach in research on welfare and migration by emphasising migrants’ own reflections and experiences.
Migrants with Irregular Status in Europe : Evolving Conceptual and Policy Challenges
This book explores the conceptual challenges posed by the presence of migrants with irregular immigration status in Europe and the evolving policy responses at European, national and municipal level. It addresses the conceptual and policy issues raised, post-entry, by this particular section of the migrant population.
Micromachined Thin-Film Sensors for SOI-CMOS Co-Integration
Co-integration of sensors with their associated electronics on a single silicon chip may provide many significant benefits regarding performance, reliability, miniaturization and process simplicity without significantly increasing the total cost. Micromachined Thin-Film Sensors for SOI-CMOS Co-integration covers the challenges and interests and demonstrates the successful co-integration of gas-flow sensors on dielectric membrane, with their associated electronics, in CMOS-SOI technology.
Microbial Phosphate Solubilization
Last decade has seen a significantly increased knowledge about phosphate solubilizing microorganisms. Sixty specialists from thirteen countries met in Salamanca to discuss the problems of the high P-unavailability as a soil nutrient for crops, and the hazards of an increasing phosphate input to aquatic habitats from industrial and mining activities, sewage disposal, detergents, and other sources. Updated solutions to enhance P-uptake by plants, bioremediation potential in the rehabilitation of ecosystems, taxonomic characterization interactions with mycorrizae, the physiological and molecular basis of PSM, and possibilities of genetic modifications of rhizospheric microorganisms were among the contributions presented. Challenges in commercializing a phosphate solubilizing microorganism were also outlined by a relevant biotech company.
Micro-, Meso- and Macro-Dynamics of the Brain
This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The topics cover the most fascinating facets of neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory and mental illness, brain controlled robots, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Overall, this volume offers an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Micro-, Meso- and Macro-Connectomics of the Brain
Highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Micro- and opto-electronic materials and Structures : Physics, mechanics, design, reliability, packaging ; Vol. I : Materials physics - materials mechanics ; Vol. II : Physical design - reliability and packaging
Micro- and Opto-Electronic Materials and Structures: Physics, Mechanics, Design, Reliability, Packaging is the first comprehensive reference to collect and present the most, up-to-date, in-depth, practical and easy-to-use information on the physics, mechanics, reliability and packaging of micro- and opto-electronic materials, assemblies, structures and systems. The chapters in these two volumes contain summaries of the state-of-the-art and present new information on recently developed important methods or devices. Furthermore, practical recommendations are offered on how to successfully apply current knowledge and recently developed technology to design, manufacture and operate viable, reliable and cost-effective electronic components or photonic devices. The emphasis is on the science and engineering of electronic and photonic packaging, on physical design problems, challenges and solutions.
mHealth Innovation in Asia : Grassroots Challenges and Practical Interventions
Offers a detailed account of a range of mHealth initiatives across South, Southeast and East Asia. It provides readers with deep insights into the challenges such initiatives face on the ground, and a view of the diverse cultural contexts shaping strategies for overcoming these challenges. The book brings together various discussions on the broader mHealth literature, and demonstrates how a research focus on diverse Asian contexts influences the success and/or failure of current mHealth initiatives. It also highlights the important roles social scientists can play in advancing theoretical approaches, as well as planning, implementing and evaluating mHealth initiatives. The book is a valuable resource for project planners, policy developers in NGOs and government institutions, as well as academics, researchers and students in the fields of public health, communications and development studies.
Methods in Gut microbial ecology for ruminants
As a result of various human activities, such as increase in human population,decrease in arable land due to soil degradation, urbanization, industrialization and associated increase in the demand for livestock products, dramatic changes are occurring in the global ruminant livestock sector. These changes includeshift inthesize of regional livestock populations and in the types of management and feeding systems under which ruminant livestock are held, and increased demand of a wider range of quality attributes from animal agriculture, not just of the products themselves but also of the methods used in their production. The livestock sector will need to respond to new challenges of increasing live stock productivity while protecting environment and human health and conservingbiodiversity and natural resources. The micro-organisms in the digestive tracts of ruminant livestock have a profound in?uence on the conversion offeedinto end products, which can impact on the- imal and theenvironment. As the livestock sector grows particularly in developing countries, there will be an increasing need to understand these processes for b- ter management and use ofbothfeed and other natural resources that underpinthe development of sustainable feeding systems.
Methods and Techniques for Cleaning-up Contaminated Sites
This publication is meant to foster links between groups facing challenges cleaning up contaminated sites through presentations that explore the problems currently being addressed and solutions that are emerging in the field.
Metal Catalyzed Cascade Reactions
Transition metal-catalyzed cascade reactions are an elegant approach to complex molecular scaffolds. Besides their esthetics and increase in structural complexity, they have also become mechanistic challenges for the combination of organometallic elementary steps. As a consequence, cascade reactions have revolutionized synthetic strategies and conceptual thinking. The authors highlight cyclization via carbopalladation and acylpalladation and Heck-pericyclic sequences. They discuss p-allyl palladium-based cascade reactions, Michael-type additions as an entry to transition-metal-promoted cyclizative transformations, and sequential or consecutive palladium-catalyzed processes, and show Pauson-Khand cascades, metal-catalyzed cyclizations of acyclic precursors, as well as cascade and sequential ruthenium-catalyzed transformations. Therefore, the reader finds overview of an exciting and highly dynamic field of a new and innovative methodological concept
Messenger RNA therapeutics
Focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine.
Medicinal compounds in modern healthcare : From tradition to innovation
Reviews the evolution, development, and application of medicinal compounds, beginning with their historical context and advancing to modern innovations. The book describes the therapeutic potential of bioactive compounds from microorganisms, the role of antioxidants and anti-inflammatory agents in managing chronic diseases, and the use of small molecules in pain management and mental healthcare. It further explores immunomodulatory compounds, epigenetic modifiers, and the latest advancements in drug development, including integrative medicine approaches and the applications of nanotechnology in traditional medicine. Additionally, the book addresses the use of immunomodulatory agents like methotrexate and paclitaxel in cancer treatment, regulatory considerations for ensuring safety and efficacy in medicinal compounds, and the growing field of nutraceuticals. Towards the end, the book covers the extraction, profiling, and ADMET evaluation of medicinal compounds, intellectual property challenges, and the significance of traditional medicine in modern healthcare.
Medical image synthesis : Methods and clinical applications
Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties.
Medical genetics and law : An international perspective
Essential resource to understanding the intersection of medical genetics and law. In a unique approach, it provides an overview on the biological principles of DNA basics and genetic inheritance linking the knowledge with the ethical and legal challenges presented by modern developments in genetics.
Mechanical Ventilation
This book represents a state-of-the-art review by the leading experts in this field and covers a number of important topics including epidemiology, underlying physiological concepts, and approaches to monitoring. The pros and cons of various modes of ventilation are reviewed, as are novel forms of ventilation that may play a role in the future management of patients with respiratory failure. The importance of patient-ventilator synchrony and ventilator-induced lung injury are reviewed, with a focus on recent clinical trials and the challenges of implementing the results into clinical practice.



















