الصفحة 4
الصفحة 4
CO-ENZYME Q10
Coenzyme Q10 (CoQ10) is a fat-soluble compound that is synthesized by the body and can be obtained from the diet. Co-Q10 plays a central role in mitochondrial oxidative phosphorylation and the production of adenosine triphosphate (ATP). It also functions as an antioxidant in cell membranes and lipoproteins. Endogenous synthesis and dietary intake provide sufficient C0- Q10 to prevent deficiency in healthy people, although coenzyme Q10 concentrations in tissues decline with age. Oral supplementation of coenzyme Q10 increases coenzyme Q10 concentrations in plasma and lipoproteins. Oral high-dose co- Q10 is usually effective to treat mitochondrial disorders that are caused by mutations in coenzyme Q10 biosynthetic genes.
Clinical toxicology : Principles and mechanisms ; 2nd ed.
Addresses the current principles and mechanisms of clinical toxicology. It examines the complex interactions associated with clinical toxicological events and chemical exposure and drug administration. The author places special emphasis on signs and symptoms of diseases and pathology caused by toxins and clinical drugs. He covers contemporary issues in clinical toxicology, such as biological and chemical toxins, changes in protocols for managing toxic ingestions, new antidotes, and changes in particular treatments. The chapters contain numerous drawings, figures, and tables to aid in comprehension.
Malaria disease and modern treatments
Some population groups are at considerably higher risk of contracting malaria and developing severe disease: infants, children under 5 years of age, pregnant women and patients with HIV/AIDS, as well as people with low immunity moving to areas with intense malaria transmission such as migrant workers, mobile populations and travellers. Malaria is an acute febrile illness caused by Plasmodium parasites, which are spread to people through the bites of infected female Anopheles mosquitoes. There are 5 parasite species that cause malaria in humans, and 2 of these species – P. falciparum and P. vivax – pose the greatest threat. P. falciparum is the deadliest malaria parasite and the most prevalent on the African continent. P. vivax is the dominant malaria parasite in most countries outside of sub-Saharan Africa.
Liver
Liver is the second largest organ in human body, more than 5,000 separate bodily functions including helping blood to clot, cleansing the blood of toxins to converting food into nutrients to control hormone levels, fighting infections and illness, regenerating back after injury and metabolizing cholesterol, glucose, iron and controlling their levels. Most people never give their liver a thought until something goes wrong, yet, liver diseases on rise, affecting one in ten. Liver diseases can be inherited or caused by a variety of factors that damage the liver.
Lean Brain Management : More Success and Efficiency by Saving Intelligence
Intelligence is wasted on problems that themselves have been caused by an excess of intelligence. Lean Brain Management strives toward uncompromising Lean Brain Quality. Lean Brain stands for consistent economization of intelligence in all realms of life: Intelligent systems will only be operated by unskilled workers. Education, universities, and schools would become obsolete. A week of training would be enough for virtually any job. ("You are now the physician for the measles in the State of Ohio. In response to phone calls, send this prescription.") Lean Brain is not aimed at dumbing down! Lean Brain can survive on just a very small amount of central intelligence. Potential savings amount to trillions! This is demonstrated using Germany as an example. With this book, Dueck presents a radical suggestion for world improvement. The desire to laugh infinitely about it will eventually segue into a collective rude awakening. The book contains concrete advice for managers to economize on intelligence, and is thus--in keeping with the theme--written in an easy-to-read fashion.
Kidney Diseases
Kidney diseases is a “hidden epidemic” affecting 850 million people worldwide. It occurs when the kidneys become damaged and can’t perform their function. Damage may be caused by diabetes, high blood pressure, and various other chronic conditions. Kidney diseases can lead to other health problems, including weak bones, nerve damage, and malnutrition. There are two main types of kidney diseases: short-term (acute kidney failure) and lifelong (chronic kidney failure). If the diseases get worse over time, the kidneys may stop working completely. This means that dialysis will be required to perform the function of the kidneys or kidney transplant. Dialysis is a treatment that filters and purifies the blood using a machine. It can’t cure kidney diseases, but it can prolong the life.
Jaundice
Jaundice in an adult patient can be caused by a wide variety of benign or life-threatening disorders. Organizing the differential diagnosis by prehepatic, intrahepatic, and posthepatic causes may help make the work-up more manageable. Prehepatic causes of jaundice include haemolysis and hematoma resorption, which lead to elevated levels of unconjugated (indirect) bilirubin. Intrahepatic disorders can lead to unconjugated or conjugated hyperbilirubinemia. The conjugated (direct) bilirubin level is often elevated by alcohol, infectious hepatitis, drug reactions, and autoimmune disorders. Posthepatic disorders also can cause conjugated hyperbilirubinemia. Gallstone formation is the most common and benign posthepatic process that causes jaundice; however, the differential diagnosis also includes serious conditions such as biliary tract infection, pancreatitis, and malignancies.
Jaundice
• Physiologic Anatomy Liver • HEMOGLOBIN FORMATION • Formation and Fate of Urobilinogen • Jaundice—Excess Bilirubin in the Extracellular Fluid • Hemolytic Jaundice Is Caused by Hemolysis of Red Blood Cells • Obstructive Jaundice Is Caused by Obstruction of Bile Ducts or Liver Disease • Diagnostic Differences Between Hemolytic and Obstructive Jaundice • Infant jaundice • Prolonged unconjugated hyperbilirubinemia associated with breast milk and mutations of the bilirubin uridine diphosphate-glucuronosyltransferase gene • Acute bilirubin encephalopathy • Hepatitis (A + B + C) • Immune system abnormaly • Jaundice in the adult
Compulsory Insurance and Compensation for Bunker Oil Pollution Damage
Oil tankers are not the only vessels that have caused oil pollution at sea. Numerous spills in the past have been of heavy fuel oil from non-tankers. However, the international liability and compensation regime covered only oil pollution damage caused by oil tankers. There was thus a need to bring the law on marine oil pollution responsive to oil pollution damage caused by non-tankers. In March 2001, the International Convention on Civil Liability for Bunker Oil Pollution Damage was adopted following a diplomatic conference at the International Maritime Organization. Though this convention has not yet come into force, its various aspects should already be considered as they will surely affect the maritime industry as a whole and the non-tanker sector, in particular. This book provides a timely and comprehensive study on the concept of compulsory insurance, its main purpose of ensuring compensation and its interrelations with other features such as the rule of strict liability and the limitation of liability under the convention.
Component-Based Software Testing with UML
Component-based software development regards software construction in terms of conventional engineering disciplines where the assembly of systems from readily-available prefabricated parts is the norm. Because both component-based systems themselves and the stakeholders in component-based development projects are different from traditional software systems, component-based testing also needs to deviate from traditional software testing approaches. Gross first describes the specific challenges related to component-based testing like the lack of internal knowledge of a component or the usage of a component in diverse contexts. He argues that only built-in contract testing, a test organization for component-based applications founded on building test artifacts directly into components, can prevent catastrophic failures like the one that caused the now famous ARIANE 5 crash in 1996. This book is the first comprehensive treatment of the intricacies of testing component-based software systems. With its strong modeling background, it appeals to researchers and graduate students specializing in component-based software engineering. Professionals architecting and developing component-based systems will profit from the UML-based methodology and the implementation hints based on the XUnit and JUnit frameworks.
Complement and Kidney Disease
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
Community-Acquired Pneumonia
Community-acquired pneumonia (CAP) is a disease associated with high morbidity and mortality, with at least one third of cases requiring hospitalization, exceeding the numbers admitted for myocardial infarction and stroke. Despite a broad armamentarium of antimicrobials available, it remains an important cause of death in industrialized countries. CAP is caused by a variety of pathogens with their order of importance dependent on the location and population studied. Despite the importance of CAP, reliable data and a recommended evidence-based therapy are lacking, and basic research must be improved. The goal of this volume is to present state-of-the-art knowledge on epidemiology, clinical presentation, immunology, pathology, and diagnosis including the identification of "new pathogens". Therapeutic approaches, antibiotics resistance, disease management and vaccination strategies are also covered. The volume is of interest to researchers and clinicians in virology, epidemiology and biomedicine.
Clinical Management of Orthodontic Root Resorption
This book in being dedicated solely to root resorption caused by orthodontic tooth movement. While the core content is based on scientific evidence, the book is intended as a practical aid for the clinician who performs orthodontics.
Classification of covid-19 in lung images
The novel coronavirus 2019 (COVID-2019), which first appeared in Wuhan city of China in December 2019, spread rapidly around the world and became a pandemic. It has caused a devastating effect on both daily lives, public health, and the global economy. It is critical to detect the positive cases as early as possible so as to prevent the further spread of this epidemic and to quickly treat affected patients. The need for auxiliary diagnostic tools has increased as there are no accurate automated toolkits available. Recent findings obtained using radiology imaging techniques suggest that such images contain salient information about the COVID-19 virus. Application of advanced artificial intelligence (AI) techniques coupled with radiological imaging can be helpful for the accurate detection of this disease, and can also be assistive to overcome the problem of a lack of specialized physicians in remote villages.
Cholera: The new burst
Cholera is an acute, secretory diarrhea caused by infection with Vibrio cholerae of the 01 and 0139 serogroups. Cholera is endemic in over fifty countries and causes large epidemics. The cholera disease outbreak has rapidly spread in Syria since September 2022. People are still suffering and fighting for their lives. The present work aims to evaluate awareness about cholera among the Syrian population. Hence, an Arabic online questionnaire was prepared using Google Forms and published throughout social internet platforms...
Children in Tort Law, Part I : Children as Tortfeasors
This volume gives answers to different questions concerning damage caused by children. Are children directly liable and is there any age limit below which they have no tortious capacity Can children, in spite of their lack of tortious capacity, for reasons of equity be held liable in exceptional conditions? What is the relationship between liability of children and liability of their parents or guardians? Are these questions answered by special rules of general application in all fields of tort liability or are there specific rules for specific torts
Chewing gum containing artemisa absinthium (Wormwood) and Vitamin B12 for Anorexia treatment
Anorexia is a medical name for loss of appetite which mean decrease appetite and it is the reason for mental and physical illness. Anorexia can accompany many diseases like infections, covid- 19, cancer, and it is also caused by many drugs. Our objective was to evaluate the level of knowledge about the anorexia among Syrian population, and, to develop chewing gum as health supplement. We used Artemisia absinthium L. (wormwood), vitamin B12 as pharmaceutical supplement ingredients, and, pine resin, or zein protein extracted from com as chewing gum bases...
Changing Land Use Patterns in the Coastal Zone : Managing Environmental Quality in Rapidly Developing Regions
Coastal ecosystems make up some of the most important, yet most endangered, regions in the world. The protection of the unique processes that take place in these ecosystems requires that partnerships be formed among ecologists, resource managers, and planners. Experienced in the challenges of coastal system analysis, the contributors to this book provide multidisciplinary guidance on the assessment and management of environmental impacts caused by development. Each chapter examines an issue important to these fragile ecosystems, first presenting a non-technical summary of the issue and a review of the current state of the knowledge, then following with data and a more detailed consideration of the topic.
Changing Forests : Collective Action, Common Property, and Coffee in Honduras
It merges political ecology, collective-action theories, and institutional analysis to study how the people and forests have changed through socioeconomic and political transitions. It studies the complex, often contradictory relationships between the people and their natural resources to understand why forest cover endures."Changing Forests" therefore encompasses three broad phases: (1) the premodern period, which considers historic perturbations in western Honduras from the period of colonialism into the middle of the twentieth century; (2) the period of state-led logging and intervention in La Campa, which caused major degradation in forest cover; and (3) the recent period in which export coffee production transformed property rights, and people’s perceptions of the forest gained new conservationist and economic dimensions. Each phase entails perspectives and experiences that influenced human use of forests, and shaped subsequent transformations.
Celiac disease
Celiac Disease is a chronic small intestinal immune-mediated enteropathy caused by the ingestion of dietary gluten proteins in genetically susceptible individuals. CD is one of the most common autoimmune diseases, affecting around 1.4% of the population globally . Celiac disease remains a challenging condition because of a steady increase in knowledge tackling its pathophysiology, diagnosis, management, and possible therapeutic options. Finding alternative diet and trying different lifestyle still under debates. However, complete exclusion of the gluten-containing food from the patient's diet is the only effective treatment to avoid the disease complications
