الصفحة 4
الصفحة 4
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Microfluidic Technologies for Miniaturized Analysis Systems

Microfluidic Technologies for Miniaturized Analysis Systems provides a comprehensive overview of the fluidic aspects of Lab-on-a-Chip technology. This book describes the most important and state-of-the-art microfluidic technologies and the underlying principles utilized in the implementation of fluidic protocols of miniaturized analysis systems. This book discusses many of the effects, outcomes, and techniques which are unique to microfluidic systems. The specific components of this technology toolbox are elucidated through research and examples presented by some of the most renowned experts in the field.

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Microbiologically Influenced Corrosion : An Engineering Insight

Microbiologically-influenced corrosion (MIC) is one of the greatest mysteries of corrosion science and engineering, due to the complexities resulting from the involvement of living things such as bacteria. Bacteria are not only able to affect our health, but are also capable of impacting upon everyday life through a wide range of industrial sectors and the economy. Microbiologically Influenced Corrosion: An Engineering Insight introduces a new approach to the basics of MIC and explains how to recognise, understand, mitigate and/or prevent this type of corrosion. Topics explored include stress corrosion cracking and microbial corrosion, the pros and cons of biocides, the involvement of magnetic bacteria in microbial corrosion, and a new interpretation of cathodic protection based on recent research in microbial environments.

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Microbial Sulfur Metabolism

In nature, sulfur occurs in many different oxidation states and is one of the most versatile elements in life. It is an integral part of many important cell constituents, such as the amino acids cysteine and methionine, and many sulfur compounds serve as the basis for energy-related processes in prokaryotes. In recent years, new methods have been applied to study the biochemistry and molecular biology of reactions of the global sulfur cycle, the microorganisms involved and their physiology, metabolism and ecology. These activities have uncovered fascinating new insights for the understanding of aerobic and anaerobic sulfur metabolism.

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Microbial Processing of Metal Sulfides

The application of microbiological methods to the extraction of metals from minerals has definitely gained a prominent role and is supported by the several bioleaching and biooxidation processes operating in different sites over the world. In recent years new techniques and new results about proteomic and bioinformatics are bringing a new perspective on the microbial processes.This book focuses on the basic aspects of the process with special emphasis on recent contributions regarding the chemical and microbial aspects of the bioleaching process and the use of microorganisms in the treatment of complex ores and concentrates.

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Microbial nutraceuticals : Products and processes

Discussion of the recent advances in the application of microbial nutraceuticals and their implementation in the health, food, and agriculture sectors. The book begins with an overview of microbial nutraceuticals before moving on to discussions of more specific topics, including microbial cell factories for the production of essential amino acids, microbial production of dietary short-chain fatty acids, and microbial sources for bioactive peptides conferring health benefits.

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Microbes and oral squamous cell carcinoma : A network spanning infection and inflammation

Helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention.

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Micro-, Meso- and Macro-Connectomics of the Brain

Highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

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Metastasis of Prostate Cancer

Without metastasis, prostate cancer would be both tolerable and treatable. The high incidence of indolent and organ confined disease is testament to this sweeping generalisation. Equally, if molecular markers of metastatic spread can be identified, then the choice of treatment for many patients would be easier and more radical, even curative. However, should prevention and treatment of the primary tumors prove difficult or impossible.

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Metals in Society and in the Environment : A Critical Review of Current Knowledge on Fluxes, Speciation, Bioavailability and Risk for Adverse Effects of Copper, Chromium, Nickel and Zinc

In 2002, the Swedish Metal Information Task Force (MITF) engaged the Environmental Research Group (MFG) to update previous monographs on copper, zinc and major alloying metals (such as chromium, nickel and molybdenum) in society and in the environment. This book presents new results on metal fluxes from society to the environment, on metal speciation in water, soil and sediment, and its interpretation in terms of mobility, biological uptake and toxicity. The scientific fundamentals of new approaches, like the Acid Volatile Sulphide (AVS) concept to predict metal bioavailability in sediments, and the Biotic Ligand Model (BLM) to calculate the toxicity of metals to aquatic organisms, are critically evaluated, with a focus on copper, nickel, zinc, and, in part, chromium.

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Mercury Pollution in Minamata

It overviews the poisoning which occurred in the 1950s and 1960s among the residents in Minamata who ate seafood contaminated with methylmercury discharged from the chemical factory, Chisso Corporation. It describes the history, symptoms pathogenesis and research on the causal agent, and discusses the responses of Chisso and the national and local governments to the outbreak, the victims, the compensation and environmental restructuring as well as the court ruling on claims. Based on lecture notes from a university course, it includes students’ suggestions for avoiding a repeat of the tragedy. The issue has not been settled yet, and this analysis of the incident provides useful insights into solutions to the current global mercury pollution problem.

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Medicinal plants and antimicrobial therapies

Serves as an excellent comprehensive material covering the current understandings and updates on antimicrobial resistance (AMR) and the use of medicinal plant resources for tackling it. Chapters cover important aspects of AMR and strategies to address this threatening issue with medicinal plants and their resources. One health perspectives for addressing AMR have been presented for the readers. Antimicrobial medicinal plant therapeutic resources including crude extracts, active fractions, pure molecules and essential oils, besides using them as functionalizing agents for nano-antimicrobials have been covered. Further, plant endophytes as a source of antimicrobial compounds have been discussed. Chapters cover both the bactericidal as well as resistance-reversal (or potentiating/ combinatorial therapies) potencies of medicinal plant resources. The book also focuses on how medicinal plant resources effectively target major determinants of AMR.

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Medical Law and Moral Rights

Medical Law and Moral Rights discusses live issue arising in modern medical practice. Do patients undergoing intolerable irremediable suffering have a moral right to physician-assisted suicide? Ought they to have a comparable legal right? Do the moral duties of a mother to care for and not abuse her child also apply to her fetus? Ought physicians to be permitted to refuse to provide medically futile treatment demanded by their patients? The author then advocates improvements in the law to make it respect our moral rights more fully. To justify his conclusions, he proposes original conceptions of the human rights to life, procreational autonomy, privacy, equitable treatment and personal security.

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Islamic Philosophy and Occidental Phenomenology on the Perennial Issue of Microcosm and Macrocosm

this volume are reviving the perennial positioning of the human condition in the play of forces within and without the human being. This theme has run from Plato through the Middle Ages, Renaissance and Modernity, and has been ignored by contemporaries. It now acquires a new pertinence and striking significance due to the scientific discoveries into the "infinitely small" in life, on the one hand, and the prodigious technological discoveries of the "infinitely great" on the other. Both open up undreamt-of prospects for the continuing conquest of cosmic forces.

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Ion channels as targets in drug discovery

Built around ion channel research and, more specifically, ion channels as important therapeutic drug targets. Under the editorial leadership of Gary Stephens in academic research and Edward Stevens from industry, the aim is to bring these strands together to provide a cutting-edge translational reference on ion channel drug discovery. Exploiting our knowledge of ion channel structure and function has clear current and future potential to intervene and correct the pathophysiology associated with debilitating conditions, including cardiovascular disease, diabetes, cystic fibrosis, pain, epilepsy, and neurodegenerative disorders. Individual chapters have a disease focus, also providing a “case study story” that will also appeal to a clinical audience

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Investigative Electrocardiography in Epidemiological Studies and Clinical Trials

It reviews the prevalence and incidence and emphasizes the prognostic implications of common ECG abnormalities in contrasting populations. It provides a comprehensive, penetrating and critical analysis of topics such as QT prolongation in clinical drug trials, left ventricular hypertrophy, myocardial ischemia/infarction and epidemiological consideration of relative risks associated with ECG abnormalities. As such it is an essential tool in epidemiological or clinical research using ECGs and in investigations of possible adverse responses of new pharmacological agents.

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Introduction to toxicology

Charts the evolution of the field of toxicology, from the use of natural toxins by ancient tribes through the developments established by Paracelsus, and progresses through to the current topics in the public interest. For centuries, the study of toxicology has fascinated students. The book begins with basic toxicological principles, including an historical summary, dose-response relationships (NEW chapter), exposure-response relationships (NEW chapter), disposition, and metabolism of xenobiotic toxic substances. Other important new chapters include target organ toxicity, toxicity of carcinogenic agents and new and updated concepts in toxicity testing, and antidotes and treatment of poisonings. In all, nine new or expanded chapters from the third edition are advanced. Current concerns about the effects of therapeutic drugs, carcinogens, industrial toxins, pesticides, and herbicides on human health, animal welfare, and the stability and maintenance of the ecosystem continue to highlight toxicology as an important and growing scientific discipline.

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Introduction to Logic and Theory of Knowledge : Lectures 1906/07

This course on logic and theory of knowledge fell exactly midway between the publication of the Logical Investigations in 1900-01 and Ideas I in 1913. It constitutes a summation and consolidation of Husserl’s logico-scientific, epistemological, and epistemo-phenomenological investigations of the preceding years and an important step in the journey from the descriptivo-psychological elucidation of pure logic in the Logical Investigations to the transcendental phenomenology of the absolute consciousness of the objective correlates constituting themselves in its acts in Ideas I. In this course Husserl began developing his transcendental phenomenology as the genuine realization of what had only been realized in fragmentary form in the Logical Investigations.

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Introduction to food chemistry

Bridges this gap in the relevant literature, as it employs the latest pedagogical theories in textbook writing to present the subject to students with broad range of cognitive skills. This book presents specific learning objectives for each chapter and is self-contained so students will not need to search for essential information outside the textbook. This new edition has been expanded to include chapters on sweeteners, glass transition, amino acids, proteins for major food commodities and food additives. All of the original chapters have been updated and expanded to include new research and technologies.

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Introduction to finite element analysis : A textbook for engineering students

Covers the basic concepts and applications of finite element analysis. It is specifically aimed at introducing this advanced topic to undergraduate-level engineering students and practicing engineers in a lucid manner. It also introduces a structural and heat transfer analysis software FEASTSMT which has wide applications in civil, mechanical, nuclear and automobile engineering domains.

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Intervention, Terrorism, and Torture : Contemporary Challenges to Just War Theory

Just war theory is the traditional approach taken to questions of the morality of war, but war today is far from traditional. War has been deeply affected in recent years by a variety of social and technological developments in areas such as international terrorism, campaigns of genocide and ethnic cleansing, the global human rights movement, economic globalization, and military technology. This book asks whether just war theory is adequate to the challenges these developments pose.

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