الصفحة 4
الصفحة 4
MRI Atlas of MS Lesions
MRI has become the main paraclinical test in the diagnosis and management of multiple sclerosis. We have demonstrated more than 400 pictures of different typical and atypical MS lesions in this atlas.
MR Cholangiopancreatography : Atlas with Cross-Sectional Imaging Correlation
Magnetic resonance cholangiopancreatography (MRCP) is a novel non-invasive technique for diagnosis of pancreatic-biliary disease. The purpose of this book is to highlight the advantages, limitations and indications of MRCP. Specific examples have been selected to showcase the utility of this technique in a large variety of clinical conditions. Each example is purposefully used to stress important technical features, to give practical advice, or to discuss the role of MRCP in specific clinical situations. Important features of the book are the high quality of the illustrations, the reduction of the text to relevant and practically useful issues, and the simple and logic organisation of the case material. The book should show: the optimal technique in MRCP, the pitfalls and limitations.
Move : Architecture in Motion - Dynamic Components and Elements
Dynamic components and adaptive elements are becoming increasingly important in contemporary architecture, and not just because of their visual effect. If architects and engineers are engaging more and more with the issue of movement – whether in the form of sun-tracking solar cells, lowerable walls, or intelligently programmed elevators – it’s because they are busy exploring responses to three challenges: How can we control and reduce the energy requirement of buildings? How can we expand the range of possible uses? And how can we represent, illustrate, accommodate, and control dynamic movements in buildings?
Mouse controller using electroencephalography (EEG) device
The growing technologies related to neuroscience has to lead many innovative applications, most importantly Electroencephalography, or EEG for short. This field of study has become recently a trend that many companies around the world have started to enter the race of conquering the brain and controlling everything from a mouse controller to the whole human body. This project aims to help disabled people use a computer with ease and simplicity without needing to use their hands, or anything really, which they can achieve by wearing a headset or get someone to put it on them. The headset is designed to read brain activities and send it to a computer program to understand where the user wants to move the mouse cursor on the computer screen using an Artificial Intelligence model. This project helps further researches in this field which pushes the technology even further from where it is now. The device designed for this project can be repurposed pretty easily to serve many different applications other than controlling a mouse.
More Joel on software : Further toughts on diverse and occasionally related matters that will prove of interest to software developers, designers, and managers, and to those who, whether by good fortune or III Luck, work with them in some capacity
Joel Spolsky started his weblog in March 2000 in order to offer his insights, based on years of experience, on how to improve the world of programming. This weblog has become infamous among the programming world, and is linked to more than 600 other web sites and translated into 30+ languages! Spolsky's extraordinary writing skills, technical knowledge, and caustic wit have made him a programming guru. With the success of Joel on Software, there has been a strong demand for additional gems and advice, and this book is the answer to those requests. Containing a collection of all–new articles from the original, More Joel on Software has even more of an edge than the original, and the tips for running a business or managing people have far broader application than the software industry.
Monograph of the Urostyloidea (Ciliophora, Hypotricha)
This monograph is the second of a series treating the hypotrichs, a major part of the spirotrichous ciliates. The urostyloids are characterised by a zigzag-arrangement of the ventral cirri. Like the first part of the series, the Oxytrichidae, it summarises the morphological, morphogenetic, faunistic, and ecological data from the past 230 years, scattered in more than 1300 references from all over the world. Dichotomous keys lead to 36 genera and subgenera comprising 153 species illustrated by more than 2100 figures, including original ones. The treatise offers taxonomists, cell biologists, and ecologists a thorough and up-to-date revision because for each species a detailed list of synonyms, a discussion of the nomenclature and systematics, and an extensive description of the morphology and ecology, including almost all published faunistic records, are provided. With the monographs of the Urostyloidea and the Oxytrichidae the interested scientist can identify more than 320 species of hypotrichs, which are an important component of the eukaryotic microbial life in limnetic, marine, and terrestrial habitats.
Molecular Markers of Brain Tumor Cells : Implications for Diagnosis, Prognosis and Anti-Neoplastic Biological Therapy
Childhood brain tumors are a diverse group of diseases characterized by the abnormal growth of tissue contained within the skull. Other than leukemia and lymphoma, brain tumors are the most common type of neoplasms that occur in children. The leading cause of death from childhood neoplasms among persons up to 19 years is brain tumors. As such, this book is a review of the most recent molecular biological research concerning brain tumors with references and comparisons to a variety of neoplastic disorders. The book then uses this information to foreshadow the direction that future anti-neoplastic therapies will take. Because of the wide spectrum of the objectives of the book, any individual involved in cancer research will greatly benefit from the work. Histopathologists, neuropathologists, clinical and research oncologists, and medical students will find this book to be an invaluable resource as a reference guide. Patients and their families will also find the book useful as it offers a comprehensive update on new, non-classical therapeutic modality options and contains a detailed description and analysis of brain tumors. Such an endeavor has yet to be undertaken by any other book and may prove to be the most comprehensive book on brain tumors thus far.
Molecular Genetics of Recombination
Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells.
Molecular Chaperones in Health and Disease
Molecular chaperones are involved in a wide variety of essential cellular processes in living cells. A subset of molecular chaperones have been initially described as heat shock proteins protecting cells from stress damage by keeping cellular proteins in a folding competent state and preventing them from irreversible aggregation. Later it became obvious that molecular chaperones are also expressed constitutively in the cell and are involved in complex processes such as protein synthesis, intracellular protein transport, post-translational modification and secretion of proteins as well as receptor signalling. Hence, it is not surprising that molecular chaperones are implicated in the pathogenesis of many relevant diseases and could be regarded as potential pharmacological targets. Starting with the analysis of the mode of action of chaperones at the molecular, cellular and organismic level, this book will then describe specific aspects where modulation of chaperone action could be of pharmacological and therapeutic interest.
Molecular Beams in Physics and Chemistry : From Otto Stern's Pioneering Exploits to Present-Day Feats
This book gives a comprehensive account of both the history and current achievements of molecular beam research. In 1919, Otto Stern launched the revolutionary molecular beam technique. This technique made it possible to send atoms and molecules with well-defined momentum through vacuum and to measure with high accuracy the deflections they underwent when acted upon by transversal forces. These measurements revealed unforeseen quantum properties of nuclei, atoms, and molecules that became the basis for our current understanding of quantum matter. This volume shows that many key areas of modern physics and chemistry owe their beginnings to the seminal molecular beam work of Otto Stern and his school. Written by internationally recognized experts, the contributions in this volume will help experienced researchers and incoming graduate students alike to keep abreast of current developments in molecular beam research as well as to appreciate the history and evolution of this powerful method and the knowledge it reveals.
Molecular Basis of Symbiosis
Symbiotic associations involving prokaryotes occur ubiquitously and are ecologically highly significant. In symbiotic associations, co-evolution of the partner organisms has led to specific mechanisms of signal exchange and reciprocal regulation, and resulted in novel physiological capabilities of the association as compared to those of the individual partners. Symbiosis research has recently entered an exciting era because molecular biology techniques are available for studying partner organisms in association and in a culture-independent manner. It is the goal of this book to contribute towards a broader perspective and an understanding of the function of symbiotic systems. 14 different model systems have been chosen, comprising well known symbioses as well as novel experimental systems which have only recently become amenable to experimental manipulation.
Molecular autoimmunity
The autoimmune disease paroxysmal cold hemoglobinuria, a rare hemolytic disorder. After a century of research, the list of autoimmune diseases has become impressive. With a prevalence of approximately 5% of the world-wide population, these chronic, debilitating conditions affect almost every major organ of the body and, for reasons that remain unclear, are much more prevalent in woman than in men. Despite our rapidly expanding knowledge of the cellular and molecular pathways that govern a normal immune response, deciphering the precise etiology of autoimmune diseases remains an important challenge. Over the last few years, our understanding of the pathogenesis of autoimmune diseases has improved rapidly, leading to the emergence of elegant immunointervention strategies. Molecular Autoimmunity illustrates how cutting-edge research is continuing to advance our understanding of autoimmune disease mechanisms and identifies novel therapeutic targets that provide a hope for effective future treatments. This volume contains a selected number of exciting advances in unraveling autoimmune reactions, and the resulting new armory of experimental immunotherapies that may lead to new ways of controlling autoimmune reactions.
Molecular and Cellular Signaling
A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determine what kinds of cells are made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular and cellular signaling in biological systems with an emphasis on the underlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadening their understanding of how cells regulate and coordinate their core activities and how diseases arise when these regulatory systems malfunction, as well as those in chemistry, physics and computer science interested in pursuing careers in biological and medical physics, bioinformatics and systems biology. To that end, the book includes background information and review sections, and chapters on signaling in the immune, endocrine (hormonal) and nervous systems. It has chapters on cancer, apoptosis and gene regulation, and contains chapters on bacteria and viruses. In those chapters not specifically devoted to pathogens, connections between diseases, drugs and signaling are made. Each chapter also features a problem set to facilitate further discussion and understanding.
Molecular analysis of B lymphocyte development and activation
The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.
Molecular analyses : Medical genomics and proteomics
Methods for extraction, manipulation, and characterization of nucleic acids, peptides, and proteins have been rapidly developed. Extraction from a variety of tissues and samples have become routine and automated. Next generation sequencing (NGS) methods have been developed. This book focuses on medically-focused methods
Modified Fibers with Medical and Specialty Applications
This book will be an invaluable resource for researchers and others interested in future developments in fiber technology. Several innovative applications for natural and synthetic fibers are described in considerable detail with emphasis on the experimental data that supports these new applications. From bandages to magnetic materials and from antibacterial clothing to implants, creative modifications to fibers are described that could one day become commonplace. Never before has this much new information about fiber modification been packaged into one book volume. In this book the world’s leading experts describe their most recent research in their areas of expertise.
Modern structural analysis : Modelling process and guidance
Essential reading for 21st century practitioners and students who need to do structural analysis. It contains a great deal of information that is not available in any other book on the subject. This is because the conventional view of structural analysis is rooted in the early part of the 20th century in the pre-computer era rather than present time.
Modern front-end architecture : Optimize your front-end development with components, storybook, and mise en place philosophy
Learn how to build front-end applications that can help you ship applications faster with fewer defects. Many software projects fail because they are not planned well, or lack organization. Applying strategies from other industries can help you create better software. Explores the “mise en place” technique from cooking and reveals how you can apply it to the art of creating software. Describes to how to structure your code base for reuse, and how to communicate the code’s intent to other developers. You’ll develop your components in isolation and test these building blocks for quality at a granular level. Then compose these components as building blocks in increasingly complicated features. Finally, you’ll apply some strategies not directly related to code to ensure maximum quality and efficiency. You will : Structure an application as a series of components / Build a component library that others in an organization can leverage / Ensure quality and accessibility at a component level rather than a page or app level / Test code in a way that gives the maximum amount of confidence while providing an excellent developer experience / Automate repeatable tasks
Modern Formal Methods and Applications
Formal methods are a robust approach for problem solving. It is based on logic and algebraic methods where problems can be formulated in a way that can help to find an appropriate solution. This book shows the basic concepts of formal methods and highlights modern modifications and enhancements to provide a more robust and efficient problem solving tool.Applications are presented from different disciplines such as engineering where the operation of chemical plants is synthesized using formal methods. Computational biology becomes easier and systematic using formal methods. Also, hardware compilation and systems can be managed using formal methods.
Modern clinic design : strategies for an era of change
A comprehensive guide to optimizing patient experience through the design of the built environment. Written by a team of veteran healthcare interior designers, architects, and engineers, this book addresses the impacts of evolving legislation, changing technologies, and emerging nontraditional clinic models on clinic design, and illustrates effective design strategies for any type of clinic. Readers will find innovative ideas about lean design, design for flexibility Understand how recent industry developments impact facility design Learn how design strategies can help create a positive patient experience Examine emerging clinic models that are becoming increasingly prevalent Analyze the impact of technology on clinic design
