الصفحة 4
الصفحة 4
Improving outcomes in oral cancer : A clinical and translational update
Brings together experts in the field of maxillofacial and head and neck oncology to provide a comprehensive clinical and translational update on oral cancer that focuses especially on prognosis. Readers will find up-to-date information on disease staging and the pathological, genetic, and surgical factors that affect patient outcomes.
Immunobiology of natural killer cell receptors
Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.
IAEA Atlas of Cardiac PET/CT : A Case-Study Approach
This book presents a wide portfolio of examples of positron emission tomography coupled with computer tomography (PET/CT) studies in various cardiac conditions in order to provide a rationale for the implementation of this technology in an array of clinical conditions. Cardiovascular diseases are a major contributor to premature morbidity and mortality worldwide. Low- and middle-income countries (LMICs) are particularly affected by cardiovascular diseases (CVDs), with more than 75% of all CVDs deaths occurring in these countries. For this reason, target 3.4 of the United Nations (UN) Sustainable Development Goals (SDGs) agenda aims at a 30% reduction in premature mortality due to non-communicable diseases (NCDs), which include CVDs, by 2030.
Human–computer interaction ; International Workshop, HCI 2007 Rio de Janeiro, Brazil, October 20, 2007 Proceedings
Constitutes the refereed proceedings of the International Workshop on Human Computer Interaction, HCI 2007, held in Rio de Janeiro, Brazil, October 20, 2007. This book covers such topics as: Affective detection and recognition, Smart interfaces, Human motion tracking, Gesture recognition, and Multimedia data modeling and visualization.
Human tooth and developmental dental defects : compositional and genetic implications
Focuses on the qualitative and quantitative properties of the sound enamel and dentin as well as the affected human tooth structures. It examines how genetics impact oral and dental health, the role of fluoride and trace elements in mineralization and the related clinical implications, and the impact of different approaches to diagnose and treat these developmental disorders.
How Data Quality Affects our Understanding of the Earnings Distribution
This book demonstrates how data quality issues affect all surveys and proposes methods that can be utilised to deal with the observable components of survey error in a statistically sound manner. This book begins by profiling the post-Apartheid period in South Africa's history when the sampling frame and survey methodology for household surveys was undergoing periodic changes due to the changing geopolitical landscape in the country. This book profiles how different components of error had disproportionate magnitudes in different survey years, including coverage error, sampling error, nonresponse error, measurement error, processing error and adjustment error.
Hormones and the brain
Peripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behaviour and aging. Depending upon intensity and duration of exposure, they can be either neuroprotective or neurotoxic, for instance by affecting production of free radicals. This book, based on contributions of pioneer investigators in the field, outlines the ambiguous actions of gonadal steroids (estradiol, progesterone, testosterone, inhibin and activin) and of neurosteroids, related moieties produced in the brain itself. After summarizing their multiple mechanisms of action, which involve both direct effects on neuronal membranes and activation of genes coding for specific proteins in neurons or glial cells, the book outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.
Honey and olive oil in diabetic foot therapy
At the beginning of the 21st Century diabetic foot is Observed, although eminently preventable, represent one of the commonest causes of hospital inpatient in Western countries. Diabetic foot is a pathological condition that might affect the feet in patients with diabetes. Foot ulcers are defined as lesions involving a skin break with loss of epithelium: they can extend into the dermis and deeper layers sometimes involving bone and muscle...
Heterogeneity in statistical genetics : How to assess, address, and account for mixtures in association studies
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.
Hemostasis in Dentistry
Offers a thorough, clinically oriented review of hemostasis and its impact on the practice of dentistry. Readers will gain a sound understanding of the pathophysiology of hemostasis and the pharmacology of antithrombotic and prothrombotic medications. Perioperative dental management strategies of value in patients with different congenital and acquired disorders of hemostasis are carefully explained, and the role of surgical techniques and local and topical agents in helping to minimize and control bleeding is described. Helpful instruction is also provided on the indications for antithrombotic medications and the management of patients receiving such therapy, including the risks of altering medications. As the number of available oral antithrombotic agents continues to increase, dentists will encounter significantly more patients receiving treatments that affect hemostasis.
Has your House Got Cracks? : A Homeowner's Guide to Subsidence and Heave Damage
Provides practical guidance for homeowners whose properties have been affected by subsidence, or heave, or who are concerned by the potential risk of damage. The first, best-selling, edition dealt specifically with the problems associated with properties founded on shrinkable clay soils, and was reprinted many times. The second edition has been expanded to include sections on other types of subsidence and causes of damage that are unrelated to foundation movement.
Handbook of urban health : Populations, methods, and practice
As more people worldwide live in cities, increasingly we need to understand how cities and city living affect population health. Does city living negatively affect health? Conversely, can city living enhance population health and well-being? Over forty experts from around the world bring a depth of ideas to the Handbook of Urban Health, making the Handbook a focused resource for a range of health disciplines. A unique professional idea book, research resource, and teaching text, the Handbook of Urban Health challenges readers to consider the role that cities plays in shaping population health and to generate solutions that can make cities healthier places for all those who live there.
Handbook of Pathogens and Diseases in Cephalopods
The aim of this book is to facilitate the identification and description of the different organs as well as pathogens and diseases affecting the most representative species of cephalopods focussed on Sepia officinalis, Loligo vulgaris and Octopus vulgaris. These species are valuable ‘morphotype’ models and belong to the taxonomic groups Sepioidea, Myopsida and Octopoda, which include most of the species with a high market value and aquaculture potential. The study is based on photographs at macroscopic and histological level in order to illustrate the role of the most important pathogens and related diseases from the view of a pathological diagnosis. The reader is able to familiarize with functional anatomy, necropsy and general histology of adults and paralarvae, as well as with the identification of different pathogens and pathologies. This work is thus an invaluable guide for the diagnosis of cephalopod diseases. Besides including pathogens for non-European cephalopod species, it also provides a useful contribution encouraging marine pathologists, parasitologists, veterinarians and those involved in fishery sanitary assessments, aquarium maintenance and aquaculture practices aiming to increase their knowledge about the pathology of cephalopods.
Handbook of Diabetes Management
Over 18 million Americans are afflicted. Nearly as many are at risk. Diabetic conditions account for one-fifth of the nation’s chronic health care burden. A public health crisis of this magnitude demands professional resources that apply evidence-based practical knowledge and anticipate the challenges that lie ahead. The Handbook of Diabetes Management is one such reference, addressing the complexity of the disease, the diversity of the populations it affects, and the continued improvement of care systems.
Handbook of Bioterrorism and Disaster Medicine
This comprehensive volume, written by experts in the field, is the essential portable handbook on bioterrorism and disaster medicine. The volume covers all pertinent topics with meticulous organization and includes an abundance of invaluable web-based resources. Written as both a practical and clinical guide to various types of disasters, it includes planning and response procedures to help mitigate the impact of disasters on affected individuals and communities. Designed to be used in the field, all the essential aspects are included: public health, bioterror agents, chemical warfare, radioactive agents, manmade disasters, natural disasters, humanitarian disasters, infectious and tropical diseases, and basics of emergency medicine. Handbook of Bioterrorism and Disaster Medicine is the ideal tool for researchers, first responders, medical students, physicians, and other healthcare providers who work in the field.
Handbook of Atopic Eczema
This second edition comprises the state of the art in pathophysiology, clinical medicine and therapeutic management. It demonstrates that there is no simple "miracle" cream, pill or diet for this disease, but that a disturbed barrier function can only be repaired by adequate and individualized skin care and it shows how unspecific anti-inflammatory treatment has to be individually tailored according to body area affected, patient age and acuity of skin lesions.
Handbook of adolescent behavioral problems : Evidence-based approaches to prevention and treatment
As we enter the new millennium, promoting sound mental health and positive behavior of adolescents has undeniably taken on greater significance than ever before. To that end, more and more research is confirming what many have suspected for years: environment and community surroundings have a major affect on an adolescent’s well-being and overall mental health. And because no single causal agent triggers teenage pathology—and no one-size-fits-all treatment is available—the Handbook of Adolescent Behavior Problems offers a comprehensive and integrative biopsychosocial approach to effective practice
Group interventions in schools : Promoting mental health for at-risk children and youth
Children who are labeled at-risk often suffer from severe deficiencies in cognitive, affective, and behavioral skills that, if unaddressed, may lead to limited prospects for future success and well-being. Tapping into the therapeutic potential of groups, this volume presents the theory and practice of cognitive-oriented group-centered counseling – combining intrinsic motivation, efficacy retraining, and targeted play therapy and social role-playing – that can be implemented to help children build core social skills and emotional regulation to complement their classroom instruction.
Groundwater and Ecosystems
Groundwater Dependent Ecosystems (GDEs) frequently exhibit rich biological diversity and can provide enormous economic wealth. In recent years, GDEs in many industrialized countries have shown signs of serious degradation, primarily the result of groundwater abstraction and pollution. Many such systems, including a number of well documented cases in Eastern Europe, are no longer sustainable. As a consequence, the conservation and sustainable management of GDEs has emerged as one of the most urgent environmental research priorities of our time. A large percentage of the world’s population lives in cities and either depends on, or is affected in some way, by groundwater. Moreover, groundwater has become a very important and complex issue that attracts the interest of many diverse stakeholders. Many problems related to groundwater and ecosystems are shared by countries throughout the world and there is growing recognition that much can be gained by co-operation on an international scale.
Glucose-6-phosphate dehydrogenase deficiency
Glucose-6-phosphate dehydrogenase deficiency, the most common enzyme deficiency worldwide, causes a spectrum of disease including neonatal hyperbilirubinemia, acute hemolysis, and chronic hemolysis. Persons with this condition also may be asymptomatic. This X-linked inherited disorder most commonly affects persons of African, Asian, Mediterranean, or MiddleEastern descent. Because acute hemolysis is caused by exposure to an oxidative stressor in the form of an infection, oxidative drug, or fava beans, treatment is geared toward avoidance of these and other stressors.
