الصفحة 4
الصفحة 4
History of Science, History of Text
This book explores the hypothesis that the types of inscription or text used by a given community of practitioners are designed in the very same process as the one producing concepts and results. The book sets out to show how, in exactly the same way as for the other outcomes of scientific activity, all kinds of factors, cognitive as well as cultural, technological, social or institutional, conjoin in shaping the various types of writings and texts used by the practitioners of the sciences. To make this point, the book opts for a genuinely multicultural approach to the texts produced in the context of practices of knowledge
High-quality outdoor learning : Evidence-based education Outside the classroom for children, teachers and society
Reviews evidence and case studies on the effects of outdoor learning on teachers and learners. It shows how real-world learning outside the classroom contributes to unlocking the full potential of learners, demonstrating its benefits for academic learning, social competencies, personal and emotional development, psychological well-being, and physical activity and health. In addition, the book highlights how outdoor learning nurtures environmental awareness and helps learners to tackle current sustainability challenges. Its focus on high-quality learning makes it a unique contribution to the implementation of SDG 4. Aimed at lecturers at teacher training universities, teachers, professional educators, coaches, and multipliers who train staff of educational NGOs, as well as decision makers on all levels of education systems, this book is of interest to all those who seek a more in-depth understanding of the future of education.
High value fermentation products ; Vol.1 : Human health
This book describes relevant aspects of industrial-scale fermentation, an expanding area of activity, which already generates commercial values of over one third of a trillion US dollars annually, and which will most likely radically change the way we produce chemicals in the long-term future. From biofuels and bulk amino acids to monoclonal antibodies and stem cells, they all rely on mass suspension cultivation of cells in stirred bioreactors, which is the most widely used and versatile way to produce.
Heterocyclic Antitumor Antibiotics
Heterocyclic Compounds Includes aspects such as synthesis, reaction mechanisms, structure complexity, properties, reactivity, stability, fundamental and theoretical studies, biology, biomedical studies, pharmacological aspects, applications in material sciences etc. Metabolism will be also included which will provide information useful in designing pharmacologically active agents. Pathways involving destruction of heterocyclic ring will also be dealt with so that synthesis of specifically functionalized non-heterocyclic molecules can be designed. Overall scope is to cover topics dealing with most of the areas of current trends in heterocyclic chemistry which will suit to a larger heterocyclic community.
Health technology assessments by the National Institute for Health and Clinical Excellence : A qualitative study
This volume dissects the robustness of the agency’s technology appraisal processes as NICE evaluates innovative methods for diagnosis and intervention. Given the unique features of attention-deficit/hyperactivity disorder (ADHD)—starting with it being diagnosed mainly in children and adolescents, its high comorbidity with other psychiatric conditions, and its considerable economic impact—the disorder is a perfect focal point for discussion.
Handbook of neurochemistry and molecular neurobiology : Sensory neurochemistry
This volume of the Handbook of Neurochemistry and Molecular Biology focuses on molecular events involved in synapse formation, synaptic plasticity and ongoing neural activity. The volume explores axonal growth cones, synapse development, and mechanisms of LTP and LTD, and calcium dynamics.
Handbook of Evidence-Based Therapies for Children and Adolescents : Bridging Science and Practice
Growing numbers of young people—some 10% to 20% of school-age populations—have mental health problems requiring intervention, and current policy initiatives identify evidence-based therapies as the most effective and relevant forms of treatment. By reviewing evidence-based treatments (EBTs) across a wide spectrum of conditions, the Handbook of Evidence-Based Therapies for Children and Adolescents: Bridging Science and Practice closes the gaps between children’s needs and services as well as those between research, training, and practice, Several EBT options, both proved and promising, are offered for each covered disorder and are bolstered by case examples, tables, and reference lists. Features include chapters on implementation issues such as diversity, family treatment, assessment strategies, and community settings, and step-by-step guidance for the researcher looking to gather empirical support for therapies.
Handbook of Behavioral and Emotional Problems in Girls
Psychopathology in children and adolescents has been extensively researched and addressed in terms of its epidemiology, expression, developmental pathways, and causes. And despite all the research studies and findings, the question remained: Are the emotional and behavioral problems of girls unique to the distinct aspects of female development, behavior, and adjustment? To fully understand and address the emotional and behavioral problems of girls, their distinct characteristics must be examined in terms of both developmental progression and context—that is, in terms of their various ethnic, cultural, socioeconomic backgrounds as well as family, school, and peer environments and influences.
Global Production : A Handbook for Strategy and Implementation
What is the best configuration for a global production network? What are the different dynamics in low-cost vs. high-cost countries? Getting the answers right is key to building a competitive and efficient global production network. Centers of economic activity are shifting profoundly, globally and even regionally. Production is shifting even more dramatically than the economy as a whole, making it critical for decision makers to know what criteria matter most and how to make the right decisions on where to invest. Regardless of the industry involved, an optimized global footprint can translate to a competitive advantage. A comprehensive redesign typically yields a 20 to 40 percent reduction in manufacturing costs. Global production and purchasing operations create a platform for entry into new markets. Planning and implementing a sustainable globalization strategy, however, takes considerable effort; this book is there to help in that task.
Geophysics of the Canary Islands : Results of Spain's Exclusive Economic Zone Program
This book contains the results of a 9 year (1995-2004) investigation of the Canary Islands Exclusive Economic Zone, using state of the art technology. The main result areas are: a multibeam survey demonstrating the magnitude of catastrophic failures of the Canary Islands; a comparison of the morphology of the Canary Islands with Hawaii; the significance of hydrothermal activity in the Canary Channel associated with Mesozoic salt diapirs; an analysis of the morphology and structure of the offshore extension of the Anaga massif in Tenerife island; a detailed description of the archipelago gravity field and magnetic field of the Canary Islands
Geology and Ecosystems
This book includes an analysis of the relationship between the different geological, hydrochemical, hydrogeological and engineering-geological processes and the processes within surface ecosystems. The analysis of specific interactions between the lithosphere and biosphere provides an integrated concept of the role of the geological environment in the evolution of the biosphere. The practical significance of the book is reflected by the analysis of modern engineering activity associated with the mining of minerals, excessive groundwater withdrawal, disposal of industrial and domestic wastes (including radioactive wastes) and their impacts on all components of the environment. Geology and Ecosystems includes a scientific approach to the complex monitoring of the environment under different natural and anthropogenic conditions, including the monitoring of permafrost regions. An important part of the book is the analysis of the "water factor" impact on ecosystems and sustainable development. Influences of intensive groundwater extraction on river flow, vegetation and land subsidence are also considered.
Gentamicin : Biosynthesis, medicinal applications and potential side effects
Discusses the biosynthesis, medicinal applications and potential side effects of Gentamicin. Topics include Gentamicin used in combination therapy and applied to medicinal materials for clinical applications; use of natural products to enhance the antibiotic activity of Gentamicin and other aminoglycosides; regiospecific Gentamicin functionalization; Gentamicin and particle engineering; and the indications and adverse effects of Gentamicin.
Garlic Extract : Interaction with mechanisms of bacterial resistance
Garlic (Allium sativum) is a medicinal plant which has a diverse biological activities including antioxidant activity, antimicrobial activity, anticancer activity and others… In this article we are focusing on its antimicrobial effect which had been tested individually and in combination with two resisted antibiotics (Ampicillin, Ciprofloxacin) on 3 gram negative bacteria (Proteus mirabilis, klebsiella pneumoniae and Enterobacter aerogenes) to estimate the effect of garlic extract on the activity of the resisted drugs and bacterial resistance mechanism.
Frontiers in Anti-Infective Drug Discovery ; Vol.9
Covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs
Foundations of Sport-Related Brain Injuries
A major take-home point from this book should be the assumption that symptom resolution does not necessarily mean injury resolution. As can be seen by research focusing on global metabolic cascades and neural activity of the brain, long-standing dysfunctional pathways continue to exist for extended periods of time even after a minor concussion. Until we completely understand the consequences of short-term perturbations and long-term residual brain dysfunctions, concussions must be treated with respect and given a higher priority for continued research activity.
Food lens = فود لينس
Food lens is an innovative application designed to revolutionize dietary management by leveraging advanced image recognition and nutritional analysis. The primary objective of this senior project is to develop a user-friendly tool that identifies various foods through a camera interface and provides detailed nutritional information. This application not only enhances the user's understanding of their dietary intake but also assists in achieving personalized health and fitness goals. The core functionality of Food Lens involves the integration of a robust image recognition system capable of accurately identifying a wide range of foods. Upon identification, the application retrieves comprehensive nutritional data, including calorie content, macronutrient distribution (proteins, fats, carbohydrates), and essential micronutrients (vitamins and minerals). This data is then seamlessly integrated into the user's dietary profile. Food Lens is designed to track the user's daily caloric intake and compare it against personalized recommendations based on age, gender, weight, height, and activity level. By maintaining a dynamic record of consumed foods, the application provides real-time feedback on the user’s nutritional progress. This feature is particularly beneficial for individuals aiming to manage weight, address dietary restrictions, or improve overall health.
Food - drug interactions
The effect of drug on a person may be different than expected because that drug interacts with another drug the person is taking (drug-drug interaction), food, beverages, dietary supplements the person is consuming (drug-nutrient/food interaction) or another disease the person has (drug-disease interaction). A drug interaction is a situation in which a substance affects the activity of a drug, i.e. the effects are increased or decreased, or they produce a new effect that neither produces on its own. These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances. Regarding food-drug interactions physicians and pharmacists recognize that some foods and drugs, when taken simultaneously, can alter the body's ability to utilize a particular food or drug, or cause serious side effects.
Fluconazole : Pharmacology, clinical uses and health effects
Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. In this book, the authors present current research in the study of the pharmacology, clinical uses and health effects of fluconazole. Topics discussed include the utilization of fluconazole in adult intensive care units; the use of fluconazole in veterinary species and a description of variances from the human experience as well as findings in veterinary species which may have applicability in human medicine; common clinical uses and in vitro activity features on fluconazole; and the discovery and development of medically-important antifungal agents, particularly the azole derivatives and the development of fluconazole and its clinical applications.
Fighting Terror Online : The Convergence of Security, Technology, and the Law
This book presents the position that the online environment is a significant and relevant theater of activity in the fight against terror, and will identify the threats, the security needs, and the issues that are unique to this environment. We examine whether the unique characteristics of this environment require new legal solutions, or whether existing solutions are sufficient. Three areas of online activity are identified that require reexamination: security, monitoring, and propaganda. For each of these, we will indicate the issues, examine existing legal arrangements, and offer guidelines for formulating legal policy. There is a demonstrated need to relate to the digital environment as a battlefront, map the new security threats.
Ferroptosis : Methods and protocols
A comprehensive collection of experimental protocols for investigating ferroptosis in different systems, including cultured cells, animal models, and human tissues. The techniques covered in this book look at various aspects of ferroptosis ranging from the detection of lipid peroxidation to the measurement of glutathione peroxidase activity and the evaluation of mitochondrial morphology. Chapters also discuss basic molecular biology methods such as quantitative PCR and immunoblotting, and advanced imaging techniques such as transmission electron microscopy and confocal fluorescence microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
