الصفحة 39
الصفحة 39
Deciphering Growth
Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children.
David Paul von Hansemann : Contributions to Oncology : Context, Comments and Translations
Presents translations of all the relevant German texts, and analyses the background and context of Hansemann's theories as well as the reasons why he was almost completely forgotten. It shows that some of Hansemann’s ideas may still be relevant to cancer research today, and that he deserves to be remembered in relation to cancer as Vordenker unter den führenden Denkern seiner Zeit - The foremost of the leading thinkers of his time.
Database systems for advanced applications ; Vol. 3453 ; 10th international conference, DASFAA 2005, Beijing, China, April 17-20, 2005, Proceedings
Data Stream Mining and Resource Adaptive Computation.- Purpose Based Access Control for Privacy Protection in Database Systems.- Complex Networks and Network Data Mining.- Bioinformatics.- Indexing DNA Sequences Using q-Grams.- PADS: Protein Structure Alignment Using Directional Shape Signatures.- LinkageTracker: A Discriminative Pattern Tracking Approach to Linkage Disequilibrium Mapping.- Watermarking and Encryption.- Query Optimization in Encrypted Database Systems.- Watermarking Spatial Trajectory Database.- Effective Approaches for Watermarking XML Data.- XML Query Processing.- A Unifying Framework for Merging and Evaluating XML Information.- Efficient Evaluation of Partial Match Queries for XML Documents Using Information Retrieval Techniques.- PathStack: A Holistic Path Join Algorithm for Path Query with Not-Predicates on XML Data.- XML Coding and Metadata Management.- An Improved Prefix Labeling Scheme: A Binary String Approach for Dynamic Ordered XML.- Efficiently Coding and Indexing XML Document.- XQuery-Based TV-Anytime Metadata Management.- Data Mining.- Effective Database Transformation and Efficient Support Computation for Mining Sequential Patterns.
Data Quality and Record Linkage Techniques
This book helps practitioners gain a deeper understanding, at an applied level, of the issues involved in improving data quality through editing, imputation, and record linkage. The first part of the book deals with methods and models. Here, we focus on the Fellegi-Holt edit-imputation model, the Little-Rubin multiple-imputation scheme, and the Fellegi-Sunter record linkage model. Brief examples are included to show how these techniques work. In the second part of the book, the authors present real-world case studies in which one or more of these techniques are used. They cover a wide variety of application areas. These include mortgage guarantee insurance, medical, biomedical, highway safety, and social insurance as well as the construction of list frames and administrative lists.
Data Mining in Biomedicine
This volume presents an extensive collection of contributions covering aspects of the exciting and important research field of data mining techniques in biomedicine. Coverage includes new approaches for the analysis of biomedical data; applications of data mining techniques to real-life problems in medical practice; comprehensive reviews of recent trends in the field. The book addresses incorporation of data mining in fundamental areas of biomedical research: genomics, proteomics, protein characterization, and neuroscience.
Data Mining for Biomedical Applications ; PAKDD 2006 Workshop, BioDM 2006, Singapore, April 9, 2006, Proceedings
This book constitutes the refereed proceedings of the International Workshop on Data Mining for Biomedical Applications, BioDM 2006, held in Singapore in conjunction with the 10th Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD 2006). The 14 revised full papers presented together with 1 keynote talks were carefully reviewed and selected from 35 submissions. The papers are organized in topical sections on protein-protein interactions, database and search, bio data clustering, and in-silico diagnosis.
Data Mining and Bioinformatics ; 1st International Workshop, VDMB 2006, Seoul, Korea, September 11, 2006, Revised Selected Papers
This volume contains the papers presented at the inaugural workshop on Data Mining and Bioinformatics at the 32nd International Conference on Very Large Data Bases (VLDB). The purpose of this workshop was to begin bringing - gether researchersfrom database, data mining, and bioinformatics areas to help leverage respective successes in each to the others.
Data Integration in the Life Sciences ; Vol. 4075 ; 3rd International Workshop, DILS 2006, Hinxton, UK, July 20-22, 2006, Proceedings
Data management and data integration are fundamental problems in the life sciences. Advances in molecular biology and molecular medicine are almost u- versallyunderpinned by enormouse?orts in data management,data integration, automatic data quality assurance, and computational data analysis. Many hot topics in the life sciences, such as systems biology, personalized medicine, and pharmacogenomics, critically depend on integrating data sets and applications producedby di?erent experimentalmethods, in di?erent researchgroups,andat di?erent levels of granularity.
Data integration in the life sciences ; Vol. 3615 ; 2nd international workshop, DILS 2005, San Diego, CA, USA, July 20-22, 2005, Proceedings
Constitutes the refereed proceedings of the Second International Workshop on Data Integration in the Life Sciences, DILS 2005, held in San Diego, CA, USA in July 2005. The papers are organized in sections on user applications, ontologies, data integration, and others, and address the issues in data integration from the life science point of view.
Data Integration in the Life Sciences ; 5th International Workshop, DILS 2008, Evry, France, June 25-27, 2008. Proceedings
This book constitutes the refereed proceedings of the 5th International Workshop on Data Integration in the Life Sciences, DILS 2008, held in Evry, France in June 2008.
Data Integration in the Life Sciences ; 4th International Workshop, DILS 2007, Philadelphia, PA, USA, June 27-29, 2007, Proceedings
it cover a wide spectrum of theoretical and practical issues including scienti?c work?ows, - notation in data integration, mapping and matching techniques, and modeling of life science data. It presenting research on new models, methods, or algorithms and 6 papers presenting imp- mentation of systems or experience with systems in practice.
Data and Text Processing for Health and Life Sciences
This book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and mine literature, and to explore the semantics encoded in biomedical ontologies. To store data this book relies on open standard text file formats, such as TSV, CSV, XML, and OWL, that can be open by any text editor or spreadsheet application.
Cytokines in the Genesis and Treatment of Cancer
Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume’s first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress — both in animal models and humans — in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field.
Cyclin Dependent Kinase 5 (Cdk5)
Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during development as well as in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role that Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may have therapeutic potential for the treatment of a number of neurodegenerative diseases.
Cyberspace security and defense : Research issues ; Proceedings of the NATO advanced research workshop on cyberspace security and defense : Research issues, Gdansk, Poland, from 6 to 9 September 2004.
The development of Internet, mobile communications, distributed computing, computer software and databases storing essential enterprise information has helped to conduct business and personal communication between individual people. and it has created many opportunities for abuse, fraud and expensive damage. This book is a selection of the best papers presented at the NATO Advanced Research Workshop dealing with the Subject of Cyberspace Security and Defense. The level of the individual contributions in the volume is advanced and suitable for senior and graduate students, researchers and technologists who wish to get some feeling of the state of the art in several sub-disciplines of Cyberspace security.
Cyanobacterial Harmful Algal Blooms : State of the Science and Research Needs
Humans can be exposed to cyanobacterial toxins by drinking water that contains the toxins, swimming in water that contains high concentrations of cyanobacterial cells, or breathing air that contains cyanobacterial cells or toxins (while watering a lawn with contaminated water, for example). Health effects associated with exposure to high concentrations of cyanobacterial toxins include: - stomach and intestinal illness; -trouble breathing; - allergic responses; - skin irritation; - liver damage; and neurotoxic reactions, such as tingling fingers and toes. Scientists are exploring the human health effects associated with long-term exposure to low levels of cyanobacterial toxins. Some studies have suggested that such exposure could be associated with chronic illnesses, such as liver cancer and digestive-system cancer. This monograph contains the proceedings of the International Symposium on Cyanobacterial Harmful Algal Blooms held in Research Triangle Park, NC, September 6-10, 2005.
Current Topics in Innate Immunity
This volume represents a collection of topics on natural killer cells, mast cells, phagocytes, toll like receptors, complement, host defense in plants and invertebrates, evasion strategies of microorganisms, pathophysiology, protein structures, design of therapeutics, and experimental approaches discussed during the conference.
Current Topics in Complement
Complement has been regarded as a pivotal effector arm of the innate immune response. Many scientists convened at the Third Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics, to discuss the advances in this field. This volume represents a collection of topics discussed during the conference.
Current techniques and materials in dentistry
Dental implants are one of the most interesting dental treatments. PEEK (polyetheretherketone) has recently been reported as a further innovation in polymer implant materials, although it has not yet met the requirements to be a biomechanical requirement. In the placement of mini-screws used in orthodontic treatments, micro-cracks caused by overtorquing in thick and hard bone, and the consequent heat production, can reduce the success rate. Computer-aided design/computer-aided manufacturing (CAD/CAM) techniques are becoming increasingly popular. Since complete dentures can be produced using an additive (3D printing) or subtractive (milling) process, CAD/CAM techniques for denture fabrication have many clinical and laboratory advantages.
Current Perspectives in microRNAs (miRNA)
In this book, many new perspectives of the miRNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide significant insight into the various mechanisms of miRNAs but also offer a great opportunity in developing new therapeutic interventions.
