الصفحة 37
الصفحة 37
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Inflammation and natural products ; 1st ed.

Brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes.

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Inference in Hidden Markov Models

This book is a comprehensive treatment of inference for hidden Markov models, including both algorithms and statistical theory. Topics range from filtering and smoothing of the hidden Markov chain to parameter estimation, Bayesian methods and estimation of the number of states.In a unified way the book covers both models with finite state spaces, which allow for exact algorithms for filtering, estimation etc. and models with continuous state spaces (also called state-space models) requiring approximate simulation-based algorithms that are also described in detail. Simulation in hidden Markov models is addressed in five different chapters that cover both Markov chain Monte Carlo and sequential Monte Carlo approaches. Many examples illustrate the algorithms and theory. The book also carefully treats Gaussian linear state-space models and their extensions and it contains a chapter on general Markov chain theory and probabilistic aspects of hidden Markov models.

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Infection Control in the Intensive Care Unit

Infection Control in the Intensive Care Unit has been entirely rewritten in this second edition. All statements are justified by the best available evidence, avoiding unsubstantiated expert opinion. The book contains a new section dedicated to the microbiology of the critically ill, specifically, how to process and interpret surveillance cultures to distinguish the ‘normal’ from the ‘abnormal’ carrier state. There are five totally new chapters dealing with evidence-based infection control molecular techniques for outbreak analysis; clinical virology in neonatal, paediatric and adult intensive care; the six basic principles of the therapy of an infection; and the role of the pharmacist in infection control. Attention is given to special topics such as nutrition, gut mucosal protection and the control of antimicrobial resistance. The addition of enteral to parenteral antimicrobials contributes to the control of multi-resistant micro-organisms. This completely revised second edition is a ‘must have’ for anyone requiring in depth knowledge in the ever expanding field of infection control.

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Infection control in the dental office : A global perspective

This book reviews the principles of infection control and the guidelines and standards of care in multiple countries, discussing them within the context of the practice of dentistry. The aim is to enable dental practitioners to ensure that the appropriate measures are adopted for each patient contact, thereby minimizing the risk of transmission of infection – a goal that is becoming ever more important given the threats posed by new or re-emerging infectious diseases and drug-resistant infections.

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Industrial Project Management : Planning, Design, and Construction

This book describes – in a precise but practical way – the most recent principles and techniques of project management, at the highest international standards, with a fully company-wide, process-based, multi-project approach. It is unique because of the integration of project management fundamentals with the practices of international contracting, which characterize planning, design and construction of large works (such as plants and machinery) in the industrial sectors. The rigorous academic approach is mixed with the managerial contribution of Danieli, one of the largest worldwide suppliers of equipment and plants to the metals industry. The project management of the latter is described alongside how it can be effectively applied to win and manage large international contracts.

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Indigenous pathways, transitions and participation in higher education : From policy to practice

This book brings together contributions by researchers, scholars, policy-makers, practitioners, professionals and citizens who have an interest in or experience of Indigenous pathways and transitions into higher education. University is not for everyone, but a university should be for everyone. To a certain extent, the choice not to participate in higher education should be respected given that there are other avenues and reasons to participate in education and employment that are culturally, socially and/or economically important for society. Those who choose to pursue higher education should do so knowing that there are multiple pathways into higher education and, once there, appropriate support is provided for a successful transition.

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Indigenous Cultures and Sustainable Development in Latin America

This book outlines development theory and practice over time as well as critically interrogates the “cultural turn” in development policy in Latin American indigenous communities, specifically, in Guatemala, Honduras, Ecuador, and Bolivia.

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Independent component analysis and signal separation ; 7th International Conference, ICA 2007, London, UK, September 9-12, 2007, Proceedings

Independent Component Analysis and Signal Separation has applications at the intersection of many science and engineering disciplinesconcernedwithunderstandingandextractingusefulinformationfrom data as diverse as neuronal activity and brain images, bioinformatics, com- nications, the World Wide Web, audio, video, sensor signals, or time series.

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Independent Component Analysis and Blind Signal Separation ; 6th International Conference, ICA 2006, Charleston, SC, USA, March 5-8, 2006, Proceedings

This book constitutes the refereed proceedings of the 6th International Conference on Independent Component Analysis and Blind Source Separation, ICA 2006, held in Charleston, SC, USA, in March 2006. The 120 revised papers presented were carefully reviewed and selected from 183 submissions. The papers are organized in topical sections on algorithms and architectures, applications, medical applications, speech and signal processing, theory, and visual and sensory processing.

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Inclusion, Education and Translanguaging : How to Promote Social Justice in (Teacher) Education?

This book is designed as an international anthology on the broader subject of inclusion, education, social justice and translanguaging. Prefaced by Ofelia García, the volume unites conceptional and empirical contributions focusing on various actors within educational institutions, from early childhood to secondary education and teacher training, while offering insights into multiple European and North-American educational systems.

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In Vivo Models of Inflammation ; Vol. II

In Vivo Models of Inflammation (Vol. 2) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation.

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In Vivo Models of Inflammation ; Vol. I

In Vivo Models of Inflammation (Vol. 1) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation.

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In vivo Models of HIV Disease and Control

An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV. Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey, mouse, cat, cow, horse, and other animal viruses are detailed and compared to HIV. Also included are chapters on the history and future of animal models, as well as a chapter on ethical and safety considerations in using animal models for AIDS studies.

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In Vitro Drug Release Testing of Special Dosage Forms

Covers the in vitro release testing of: lipid based oral formulations; chewable oral drug products; injectables; drug eluting stents; inhalation products; transdermal formulations; topical formulations; vaginal and rectal delivery systems and ophthalmics. The book concludes with a look at regulatory aspects. Covers both oral and non-oral dosage forms Describes current regulatory conditions for in vitro drug release testing Features contributions from well respected global experts in dissolution testing

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Impulse Breakdown of Liquids

The book describes the main physical processes and phenomena in pulsed electric breakdown. The knowledge and the control of the electric breakdown of liquids is important not only for the insulation inside power systems but it is also used for the creation and information of high voltage and high current pulses. Such high-voltage micro- and nanosecond pulses find wide application in experimental physics, electro discharge technology, physics of dielectrics, radar detection and ranging, high-speed photography. The nature of charge carriers, mechanism of formation and evolution of the gas phase, and their role in charge ignition (initiation) and development are considered. In particular, the spatiotemporal laws of propagation and parameters of charge channels are described in detail and the boundery conditions of the breakdown initiation are formulated.

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Improving operating leverage using hyperautomation : Unlock strategic advantages across banking and non-banking financial institutions

Delving in depth into enterprise non-interest operating cost management and operating leverage. operating Leverage is about managing a bank's capabilities and its capacity to deliver its products and services efficiently. it is not limited to managing operational costs but includes the operational support for the growth of business and for improving profitability. the reader can learn to improve risk adjusted operational effectiveness by implementing a nuanced approach to managing performance, risk, control, and cost simultaneously, at the process level. the book explains why hyperautomation, a technology that intelligently automates business processes is a more advanced and comprehensive way to manage these factors in a holistic and integrated way.

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Improving Interagency Collaboration, Innovation and Learning in Criminal Justice Systems : Supporting Offender Rehabilitation

This book to improve collaboration between criminal justice and welfare services in order to help prepare offenders for life after serving a prison sentence. It examines the potential tensions between criminal justice agencies and other organisations which are involved in the rehabilitation and reintegration of offenders, most notably those engaged in mental health care or third sector organisations

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Improving Inclusive Education through Universal Design for Learning

Provides an analysis of how the educational strategy of Universal Design for Learning can stimulate the process of inclusive education in different educational-cultural contexts and different areas of the educational system. The findings of the research deepen the conception of inclusive education and present an analysis of factors that are significant for developing the educational system as well as providing evidence-based recommendations for educational practice. The research for this work was done in four European countries with various historical-cultural contexts: Lithuania and Poland underwent a transformation of the educational systems at the turning point in their political system, shifting from a strictly centralized Soviet policy to a liberal and democratic education system; Austria has experienced changes in social stratification and a need for cultural harmonisation arising from active national migration processes, whereas Finland has been gradually developing a socio-democratic model of national welfare.

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IMPROVE - Innovative modelling approaches for production systems to raise validatable efficiency : Intelligent methods for the factory of the future

This open access work presents selected results from the European research and innovation project IMPROVE which yielded novel data-based solutions to enhance machine reliability and efficiency in the fields of simulation and optimization, condition monitoring, alarm management, and quality prediction.

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Implementing responsible research and innovation : Organisational and national conditions

we give an overview of the book and the RRI-Practice study. The book is an analysis of data collected in the RRI-Practice study. It comprises an organizational analysis and an analysis of national discourses, thus analysing conditions for the uptake of RRI in research funding and research performing organisations in the science system.

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