الصفحة 37
الصفحة 37
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Lectins

In the intervening years well over 10,000 articles have appeared with lectins as the main subject, and more than twice as many in which they were touched upon, as well as around 20 books. In particular, great strides have been made in several areas of lectin research, about which little was known until the late 1980s. One prominent example is animal lectins, many of which have been discovered only during the last decade and the functions of several of which have been clarified, especially as to their key role in innate immunity.

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Learning in Economic Systems with Expectations Feedback

Recently economists have more and more focussed on scenarios in which agents' views of the world may be erroneous. These notes introduce the concept of perfect forecasting rules which provide best least-squares predictions along the evolution of an economic system.

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Layered Double Hydroxides

Both experimental and theoretical studies of nearly every aspect of the LDH structure are discussed, including the range of metal cations and interlayer anions, M 3+ /M 2+ ratios, LDH polytypes, arrangement of the "interlayer" anions and water molecules, molecular modeling and molecular dynamics simulations, and the long- and short-range order in both the layers and interlayer galleries. Of especial value is the treatment of the more detailed aspects of the LDH structure that are still unresolved.

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Lateral Alignment of Epitaxial Quantum Dots

Accurate positioning of self-organized nanostructures on a substrate surface can be regarded as the Achilles’ heel of nanotechnology. This perception also applies to self-assembled semiconductor quantum dots. This book describes the full range of possible strategies to laterally align self-assembled quantum dots on a substrate surface, starting from pure self-ordering mechanisms and culminating with forced alignment by lithographic positioning. The text addresses both short- and long-range ordering phenomena and paves the way for the future high integration of single quantum dot devices on a single chip. Contributions by the best-known experts in this field ensure that all relevant quantum-dot heterostructures are elucidated from diverse relevant perspectives.

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Laser Ablation and its Applications

Laser Ablation and its Applications emphasizes the wide range of these topics rather than focusing on one specialty or discipline. It is intended for a graduate course in laser interactions with plasmas and materials, but it should be accessible to anyone with a graduate degree in physics or engineering.

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Laboratory control system operations in a GMP environment

In Laboratory Control System Operations in a GMP Environment, readers are given the guidance they need to implement a CGMP compliant Laboratory Control System (LCS) that fits within Global Regulatory guidelines. Using the Quality Systems Approach, regulatory agencies like the FDA and the European Medicine Agency have developed a scheme of systems for auditing pharmaceutical manufacturing facilities which includes evaluating the LCS.

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La correspondance entre Henri Poincaré et les physiciens, chimistes et ingénieurs = The correspondence between Henri Poincaré and physicists, chemists and engineers

Cosmic microwave background radiation is the residue of the great heat following the Big Bang. A tenuous sign, over 13 billion years old, in which the answers to many of the questions about the nature of our Universe are hidden. Discovered by chance in 1964, in the last forty years this fossil trace of the origins of the Cosmos has been explored with every available means. Two Nobel Prizes in physics have already been awarded for research involving it, the last in 2006 for the results of the COBE satellite. Much of the information encoded in the cosmic background radiation was impressed by the superimposition of acoustic waves present in the early Universe: a "music" of the Big Bang, which cosmologists have tried for years to reconstruct, using techniques similar to those that allow to distinguish the sound of different musical instruments. Only recently have the first notes of this extraordinary cosmic symphony finally been revealed, but the investigation is not over yet. This book illustrates, with a language suitable even for non-specialists, the theories, observations and discoveries that have brought cosmology into a new era.

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KRAS : Methods and protocols

Details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models.

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Kramers-Kronig Relations in Optical Materials Research

This is the first one-volume work to provide a thorough and comprehensive description of the physical background, rigorous theory and applications of Kramers-Kronig relations in the fields of linear and nonlinear optical spectroscopy. Currently, Kramers-Kronig relations have become basic tools in the investigation of the optical properties of materials. A brief presentation of the related data-retrieval technique, the maximum entropy method, is also given. The contents and style potentially make this a standard text for physicists, chemists and engineers interested in optical-materials research and development.

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Kinetics of Water-Rock Interaction

Systems at the surface of the Earth are continually responding to energy inputs derived from solar radiation or from the radiogenic heat in the interior. These energy inputs drive plate movements and erosion, exposing metastable mineral phases at the Earth’s surface. In addition, these energy fluxes are harvested and transformed by living organisms. As long as these processes persist, chemical disequilibrium at the Earth’s surface will be perpetuated. Chemical disequilibrium is also driven by human activities related to production of food, extraction of water and energy resources, and burial of wastes. To understand how the surface of the Earth will change over time, we must understand the rates at which reactions occur and the chemical feedbacks that relate these reactions across extreme temporal and spatial scales. This book addresses fundamental and applied questions concerning the rates of water-rock interactions driven by tectonic, climatic, and anthropogenic forcings.

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Kinetics of Catalytic Reactions--Solutions Manual

This textbook contains all the information needed for graduate students or industrial researchers to design kinetic experiments involving heterogeneous catalysts, to characterize these catalysts, to acquire valid rate data, to verify the absence of mass (and heat) transfer limitations, to propose reaction models, to derive rate expressions based on these models and, finally, to assess the consistency of these rate equations.The most recent technique to calculate heats of adsorption and activation barriers on metal surfaces, the BOC-MP approach, is discussed in detail. Methods to measure metal surface areas and crystallite sizes using x-ray diffraction, transmission electron microscopy and various chemisorption techniques are discussed. Different experimental techniques to determine the influence of mass transfer limitations, especially within the pores of a catalyst, are reviewed in detail, with a particular emphasis on liquid-phase reactions.

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Kinetics of Catalytic Reactions

This textbook contains all the information needed for graduate students or industrial researchers to design kinetic experiments involving heterogeneous catalysts, to characterize these catalysts, to acquire valid rate data, to verify the absence of mass (and heat) transfer limitations, to propose reaction models, to derive rate expressions based on these models and, finally, to assess the consistency of these rate equations.Many illustrations of these and other topics are provided along with numerous problems and a Solutions Manual for instructors. This book will be applicable to any graduate course in chemical engineering, chemistry or materials science that involves kinetics of catalytic reactions, including those catalyzed by enzymes.

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Kindling 6

A broad array of themes concerned with research on epilepsy and kindling is covered in the book: Pathogenesis of kindling, including developmental patterns; electrophysiology; anatomy, morphology, and neural circuitry; genes, species, and strains; synaptic pharmacology and neurochemistry ; Behavioral consequences of kindling ; Drugs and interventions against kindling ; Clinical relevance of kindling for our understanding of epilepsy in patients

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Kinase Drug Discovery : Modern Approaches

Kinase inhibition remains an area of significant interest, and growing importance, across academia and the pharmaceutical industry. There are now many marketed drugs that target kinases and a significant number of compounds are currently in various stages of clinical development. This book is a forward-looking analysis of a number of key areas for kinase inhibition in the coming years and builds on the first volume. This includes topics such as screening approaches to target kinases along with different modes of inhibition such as allosteric and covalent. Novel approaches such as macrocyclisation are considered along with how the properties of kinase inhibitors have evolved, including the potential for brain penetration. Recent areas of great importance also covered include cutting edge molecular modelling approaches and the importance of kinase mutations.

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IUTAM Symposium on Physicochemical and Electromechanical Interactions in Porous Media

The purpose of the IUTAM symposium from which this proceedings volume has been compiled was to dive deep into the mechanics of those porous media that involve mechanics and chemistry, mechanics and electromagnetism, mechanics and thermal fluctuations of mechanics and biology.

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Computational biology in drug discovery and repurposing

Takes an in-depth look at the emerging and prospective field of computational biology and bioinformatics, which possesses the ability to analyze large accumulated biological data collected from sequence analysis of proteins and genes and cell population with an aim to make new predictions pertaining to drug discovery and new biology. The book explains the basic methodology associated with a bioinformatics and computational approach in drug designing. It then goes on to cover the implementation of computational programming, bioinformatics, pharmacophore modeling, biotechnological techniques, and pharmaceutical chemistry in designing drugs. The major advantage of intervention of computer language or programming is to cut down the number of steps and costs in the field of drug designing, reducing the repeating steps and saving time in screening the potent component for drug or vaccine designin

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Computational and Instrumental Methods in EPR

This volume is devoted to both instrumentation and computation aspects of EPR, while addressing applications such as spin relaxation time measurements, the measurement of hyperfine interaction parameters, and the recovery of Mn(II) spin Hamiltonian parameters via spectral simulation.

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Comprehensive utilization of magnesium slag by pidgeon process

This book introduces the harmless handling/recycling of magnesium slag , the process of magnesium silicothermic reduction (Pidgeon process)which the slag was produced, and . the magnesium resources, layout of the industry of the world. Examples and experimental data in this book are from the author group’s research programs, as well as the rencent researches in China. The book could provide precious reference to scientists and engineers in the field of recycling and environment friendly use of the industrial solid wastes. It could also be used for researchers and students who are interested in relevant field.

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Comprehensive biochemistry for dentistry : Textbook for dental students

Combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents

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Composites with micro- and nano-structure : Computational modeling and experiments

The book contains atomistic and continuum numerical methods and experimental validation for composite materials reinforced with particles or fibres, porous materials, homogenization and other important topics for research in this field.

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