الصفحة 36
الصفحة 36
Multi-Scale Approaches in Drug Discovery : From Empirical Knowledge to In silico Experiments and Back
Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.
Multi-Robot Systems. From Swarms to Intelligent Automata, Vol. III ; Proceedings from the 2005 International Workshop on Multi-Robot Systems
Documents developments in multi-robot systems research. This volume is the result of the Third International workshop on Multi-Robot Systems that was held in March 2005 at the Naval Research Laboratory in Washington, DC.
Multirate Statistical Signal Processing
This book introduces a statistical theory for extracting information from signals that have di?erent sampling rates. This new theory generalizes the conventional (deterministic) theory of multirate systems beyond many of its constraints.Furthermore,itallowsfortheformulationofseveralnewproblems such as spectrum estimation, time-delay estimation and sensor fusion in the realm of multirate signal processing. I have arrived at the theory presented here by integrating concepts from diverse areas such as information theory, inverse problems and theory of - equalities. The process of merging a variety of concepts of di?erent origin results in both merits and shortcomings. The former include the fresh and - di?erentiated view of an amateur, providing scope of application. The latter include a lack of in-depth experience in each of the original ?elds. Granted, this may lead to gaps in continuity, however it goes without saying that a complete theory can seldom be achieved by one person and in a short time.
Multi-point Interaction with Real and Virtual Objects
This edited book covers some of the most challenging problems on the forefront of today’s research on physical interaction with real and virtual objects, with special emphasis on modelling contacts between objects, grasp planning algorithms, haptic perception, and advanced design of hands, devices and interfaces.
Multiplicative Invariant Theory
Multiplicative invariant theory, as a research area in its own right within the wider spectrum of invariant theory, is of relatively recent vintage. The present text offers a coherent account of the basic results achieved thus far.. Multiplicative invariant theory is intimately tied to integral representations of finite groups. Therefore, the field has a predominantly discrete, algebraic flavor. Geometry, specifically the theory of algebraic groups, enters through Weyl groups and their root lattices as well as via character lattices of algebraic tori.
Multiplicative Ideal Theory in Commutative Algebra : A Tribute to the Work of Robert Gilmer
This volume, a tribute to the work of Robert Gilmer, consists of twenty-four articles authored by his most prominent students and followers. These articles combine surveys of past work by Gilmer and others, recent results which have never before seen print, open problems, and extensive bibliographies.
Multiplication of RNA Plant Viruses
Biochemical studies on plant virus RNA replication have advanced considerably since 2000, primarily because of new genetic, molecular, biochemical, and enzymatic studies. Certain virus-encoded essential proteins, nucleotide sequence motifs, and RNA secondary structures are central to virus RNA replication, which has a number of stages.
Multiple-Aspect Analysis of Semantic Trajectories ; First International Workshop, MASTER 2019, Held in Conjunction with ECML-PKDD 2019, Würzburg, Germany, September 16, 2019, Proceedings
This book constitutes the refereed post-conference proceedings of the First International Workshop on Multiple-Aspect Analysis of Semantic Trajectories, MASTER 2019, held in conjunction with the 19th European Conference on Machine Learning and Knowledge Discovery in Databases, ECML PKDD 2019, in Würzburg, Germany, in September 2019.
Multiple Testing Procedures and Applications to Genomics
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. The methods are applied to a range of testing problems in biomedical and genomic research, including the identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments.
Multiple Stressors : A Challenge for the Future
This book publishes the Proceedings of the NATO Advanced Research Workshop on Multipollution Exposure and Risk Assessment, Ecotoxiclogical risk from multiple stressors covers any situation where org- isms are exposed to a combination of environmental stressors. These include physical and chemical pollutants as well as other stressors such as parasites and environmental impact (e. g. , climate change or habitat loss). The combi- tion of stressors can result in increased risk to organisms (either additive or synergistic effects) or decreased effects (protective or antagonistic effects). The multiple stressor challenge is an international, multi-disciplinary problem requiring an international, multi-disciplinary approach. The c- rent approach to multiple stressors is to examine one stressor at a time and assume additivity.
Multiple Stars Across the H-R Diagram ; Proceedings of the ESO Workshop held in Garching, Germany, 12-15 July 2005
Stars show a marked tendency to be in systems of different multiplicity, ranging from simple binaries and triples to globular clusters with several 10,000's of stars. The formation and evolution of multiple systems remains a challenging part of astrophysics, and the contributions in this book report on the significant progress that had been made in this research field in the last years. The reader will find a variety of research topics addressed, such as the dynamical evolution in multiple stars, the effects of the environment on multiple system parameters, stellar evolution within multiple stars, multiplicity of massive stars, pre-main sequence and intermediate mass stars, multiplicity of low-mass stars from embedded protostars to open clusters, and brown dwarfs and extrasolar planets in multiples.
Multiple Integrals in the Calculus of Variations
From the reviews: "…the book contains a wealth of material essential to the researcher concerned with multiple integral variational problems and with elliptic partial differential equations. The book not only reports the researches of the author but also the contributions of his contemporaries in the same and related fields. The book undoubtedly will become a standard reference for researchers in these areas. …The book is addressed mainly to mature mathematical analysts. However, any student of analysis will be greatly rewarded by a careful study of this book."
Multiple Heterogeneous Unmanned Aerial Vehicles
Aerial robots can be considered as an evolution of the Unmanned Aerial Vehicles (UAVs). This book provides a quite complete overview of issues related to aerial robotics, addressing problems ranging from flight control to terrain perception and mission planning and execution. The major challenges and potentials of heterogeneous UAVs are comprehensively explored. It builds on the results of the European project COMETS, and highlights a number of key research topics in the area of UAV development, including communication, perception, teleoperation and decision making. The monograph emphasizes the current state of technology, the existing problems and potentialities of systems consisting of multiple UAVs which are heterogeneous in view of the different characteristics of the aerial vehicles, the different on-board payloads, and the different on-board information processing capabilities. The book also examines potential applications of UAVs and details a relevant application case: forest fire detection and monitoring.
Multiple Criteria Decision Analysis :State of the Art Surveys
The handbook presents the most up-to-date discussions on well-established methodologies and theories in the field, while systematically surveying emerging fields in MCDA such as conjoint measurement, fuzzy preferences, fuzzy integrals, rough sets, etc. MULTIPLE CRITERIA DECISION ANALYSIS is a valuable reference volume (more than 2000 references) for the field of decision analysis. It provides graduate students, researchers, and practitioners with a sweeping survey of MCDA theory, methodologies, and applications. It is a handbook that is particularly suitable for use in seminars in Decision Analysis, Decision Support, and Decision Theory.
Multiple Classifier Systems ; 7th International Workshop, MCS 2007, Prague, Czech Republic, May 23-25, 2007, Proceedings
These proceedings are a record of the Multiple Classifier Systems Workshop, MCS 2007, held at the Institute of Information Theory and Automation, Czech Academy of Sciences, Prague in May 2007. the workshop achieved its objective of bringing together researchers from diverse communities (neural networks, pattern rec- nition, machine learning and statistics) concerned with this research topic.
Multiple Classifier Systems ; 6th International Workshop, MCS 2005, Seaside, CA, USA, June 13-15, 2005, Proceedings
Constitutes the refereed proceedings of the 6th International Workshop on Multiple Classifier Systems, MCS 2005. This book contains papers that are organized in topical sections on boosting, combination methods, performance analysis, and applications. They exemplify the advances in the theory and applications of multiple classifier systems
Multiple Classifier Systems ; 2nd International Workshop, MCS 2001 Cambridge, UK, July 2-4, 2001 Proceedings
Driven by the requirements of a large number of practical and commercially - portant applications, the last decade has witnessed considerable advances in p- tern recognition. Better understanding of the design issues and new paradigms, such as the Support Vector Machine, have contributed to the development of - proved methods of pattern classi cation. However, while any performance gains are welcome, and often extremely signi cant from the practical point of view, it is increasingly more challenging to reach the point of perfection as de ned by the theoretical optimality of decision making in a given decision framework. The asymptoticity of gains that can be made for a single classi er is a re?- tion of the fact that any particular design, regardless of how good it is, simply provides just one estimate of the optimal decision rule.
Multiple Bonds between Metal Atoms
The 3rd edition of the Multiple Bonds between Metal Atoms deals with one of the most active fields of inorganic chemistry … . It presents an extensive, critical review and discussion of preparations, reactions, bonding, and physical properties of more than 4000 compounds … heartily recommend it to inorganic and materials chemists, and to all scientists concerned with the synthesis, spectroscopy, and structures of transition-metal compounds. It also belongs in academic, industrial, and government research libraries.
Multiple Abstraction Hierachies for Mobile Robot Operation in Large Environments
This book focuses on the efficient performance of mobile robots through the use of multi-hierarchical symbolic representations of the environment. A mobile robot intended to perform deliberative actions must possess some symbolic representation of its workspace, but such representations of real environments usually become so large that should be conveniently arranged in order to facilitate and, in some cases, make possible their use. This book addresses all these issues considering symbolic multi-hierarchical structures. Such structures, based on the concept of abstraction, allow a robot to speed up its operation in large environments. Practical solutions tested on real robots (for instance, a robotic wheelchair for elder people) are provided.
Multi-Photon Quantum Interference
Multi-Photon Quantum Interference covers the phenomena of quantum interference through the multi-photon effects of photon correlation. The author’s focus is on the temporal correlation among photons and how it influences the interference effect.
