Machine learning for neurodegenerative disorders : advancements and applications
Explores the application of machine learning to the understanding, early diagnosis, and management of neurodegenerative disorders. With a specific focus on its role in ongoing clinical trials, the book covers essential topics such as data collection, pre-processing, feature extraction, model development, and validation techniques. It delves into the applications of neuroimaging techniques like magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) in the diagnosis and understanding of neurodegenerative disorders. Additionally, the book examines various machine-learning algorithms employed for biomarker discovery in neurodegenerative disorders. It highlights the role of neuroinformatics and big data analysis in advancing the understanding and management of neurodegenerative disorders. Furthermore, the book reviews future prospects and presents the ethical considerations and regulatory challenges associated with implementing machine learning approaches in the diagnosis, treatment, and prevention of neurodegenerative disorders.
Machine learning and deep learning in medical data analytics and healthcare applications
Introduces and explores a variety of schemes designed to empower, enhance, and represent multi-institutional and multi-disciplinary machine learning (ML) and deep learning (DL) research in healthcare paradigms. Serving as a unique compendium of existing and emerging ML/DL paradigms for the healthcare sector, this book demonstrates the depth, breadth, complexity, and diversity of this multi-disciplinary area. It provides a comprehensive overview of ML/DL algorithms and explores the related use cases in enterprises such as computer-aided medical diagnostics, drug discovery and development, medical imaging, automation, robotic surgery, electronic smart records creation, outbreak prediction, medical image analysis, and radiation treatments.
Lung cancer : causes, diagnosis, treatment
Lung cancer remains the leading cause of cancer-related deaths in the United States and the world - responsible for approximately 1.8 million deaths annually Lung cancer is still expected to cause more than 4 million deaths over the next 50 years. Thus, in addition to tobacco control efforts, a focus on early detection and treatment interventions will be critical to further reducing the burden of lung cancer...
Lung biology and pathophysiology
The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lung cells in the physiological and pathological conditions critical to the development of novel therapeutics.
Longer-Term Psychiatric Inpatient Care for Adolescents : A Multidisciplinary Treatment Approach
Describes the theoretical underpinnings and operational aspects of delivering longer-term inpatient psychiatric care to adolescents experiencing severe, unremitting mental illness. The authorship is drawn from the multidisciplinary team that supports the Walker Adolescent Unit, located in Sydney, Australia. The book begins with an account of the planning and development of the unit, an examination of the physical environment, and the adaptations that have been made to ensure its functionality. There follows a consideration of the therapeutic milieu. The book describes clinical processes such as admission and discharge planning, formulation and case review. There is information about the specific roles of professionals and the therapies that they provide. The book describes the steps taken to maintain and enhance the physical wellbeing of patients. There are chapters dedicated to governance, and to training and education. The final chapter describes how the unit responded to challenges created by the COVID-19 pandemic.
Liver Radioembolization with Y90 Microspheres
Provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors.
Liposuction : Principles and Practice
Liposuction began as a contouring procedure but has evolved into the treatment of obese patients, gynecomastia, ptosis, macromastia, and even patients who have complications from heart disease or diabetes. Other disorders such as axillary sweat hypersecretion, lipomas, and angiomas are also potential disorders that may be treated with liposuction.
Linear Programming and its Applications
This book presents a unified treatment of linear programming. Without sacrificing mathematical rigor, the main emphasis of the book is on models and applications. The most important classes of problems are surveyed and presented by means of mathematical formulations, followed by solution methods and a discussion of a variety of "what-if" scenarios. Non-simplex based solution methods and newer developments such as interior point methods are covered along with a variety of approaches that incorporate multiple objectives in the model.
Linear Programming : Foundations and Extensions
Linear Programming: Foundations and Extensions is an introduction to the field of optimization. The book emphasizes constrained optimization, beginning with a substantial treatment of linear programming, and proceeding to convex analysis, network flows, integer programming, quadratic programming, and convex optimization. The book is carefully written. Specific examples and concrete algorithms precede more abstract topics. Topics are clearly developed with a large number of numerical examples worked out in detail.
Linear Optimization Problems with Inexact Data
Linear programming attracted the interest of mathematicians during and after World War II when the first computers were constructed and methods for solving large linear programming problems were sought in connection with specific practical problems—for example, providing logistical support for the U.S. Armed Forces or modeling national economies. Early attempts to apply linear programming methods to solve practical problems failed to satisfy expectations. There were various reasons for the failure. One of them, which is the central topic of this book, was the inexactness of the data used to create the models. This phenomenon, inherent in most pratical problems, has been dealt with in several ways. At first, linear programming models used "average” values of inherently vague coefficients, but the optimal solutions of these models were not always optimal for the original problem itself. Later researchers developed the stochastic linear programming approach, but this too has its limitations. Recently, interest has been given to linear programming problems with data given as intervals, convex sets and/or fuzzy sets. The individual results of these studies have been promising, but the literature has not presented a unified theory. Linear Optimization Problems with Inexact Data attempts to present a comprehensive treatment of linear optimization with inexact data, summarizing existing results and presenting new ones within a unifying framework.
Lindhe's Clinical Periodontology and Implant Dentistry ; 2 Vol. Set ; 7th ed.
Provides an introduction to anatomy, including periodontal tissues, the edentulous ridge, the mucosa at teeth and implants, and osseointegration Discusses the epidemiology of periodontal and peri-implant diseases Explores the microbiology, including dental biofilms and calculus, periodontal infections, peri-implant infections, the pathogenesis of gingivitis and periodontitis, and the genetic susceptibility to periodontal disease Includes the latest perio- and peri-implant disease classifications Contains updated evidence-based preventive and treatment modalities for the treatment of periodontal and peri-implant diseases Features the latest evidence-based therapeutic alternatives on the use of dental implants to rehabilitate the lost dentition
Lifestyle modifications : The best treatment for prediabetes
Demonstrate the physiological effects of lifestyle modification on prediabetes. Prediabetes is a condition in which individuals have blood glucose levels higher than normal but not high enough to be classified as diabetes. Prediabetes is now recognized as a reversible condition that increases an individual’s risk for development of diabetes. Lifestyle risk factors for prediabetes include overweight and physical inactivity.
Lifestyle medicine
Contains extensive sections on the treatment and prevention of coronary heart disease,stroke, cancer, diabetes, obesity, substance abuse, dementia, and many other clinical conditions. Key lifestyle modalities such as physical activity, nutrition, weight management, sleep, stress reduction, and positive connections with other humans are supported by detailed discussion and state-of-the-art evidence. The expanded section on behavioral medicine provides an important framework for these discussions. Every chapter has been completely revised and many new topics added, such as lifestyle medicine for nursing, psychiatry, and preventive neurology.
Lie Theory Vol.229 : Unitary Representations and Compactifications of Symmetric Spaces
It focuses on two fundamental questions in the theory of semisimple Lie groups: the geometry of Riemannian symmetric spaces and their compactifications; and branching laws for unitary representations, i.e., restricting unitary representations to (typically, but not exclusively, symmetric) subgroups and decomposing the ensuing representations into irreducibles.Ji's introductory chapter motivates the subject of symmetric spaces and their compactifications with carefully selected examples. A discussion of Satake and Furstenberg boundaries and a survey of the geometry of Riemannian symmetric spaces in general provide a good background for the second chapter, namely, the Borel–Ji authoritative treatment of various types of compactifications useful for studying symmetric and locally symmetric spaces. Borel–Ji further examine constructions of Oshima, De Concini, Procesi, and Melrose, which demonstrate the wide applicability of compactification techniques. Kobayashi examines the important subject of branching laws. Important concepts from modern representation theory, such as Harish–Chandra modules, associated varieties, microlocal analysis, derived functor modules, and geometric quantization are introduced. Concrete examples and relevant exercises engage the reader.
Lie Sphere Geometry : With Applications to Submanifolds
Provides a clear and comprehensive modern treatment of Lie sphere geometry and its applications to the study of Euclidean submanifolds. It begins with the construction of the space of spheres, including the fundamental notions of oriented contact, parabolic pencils of spheres, and Lie sphere transformations. The link with Euclidean submanifold theory is established via the Legendre map, which provides a powerful framework for the study of submanifolds, especially those characterized by restrictions on their curvature spheres.
Lie Groups : An Approach through Invariants and Representations
Lie groups has been an increasing area of focus and rich research since the middle of the 20th century. Procesi's masterful approach to Lie groups through invariants and representations gives the reader a comprehensive treatment of the classical groups along with an extensive introduction to a wide range of topics associated with Lie groups: symmetric functions, theory of algebraic forms, Lie algebras, tensor algebra and symmetry, semisimple Lie algebras, algebraic groups, group representations, invariants, Hilbert theory, and binary forms with fields ranging from pure algebra to functional analysis.
Lie Algebras and Applications
This book, designed for advanced graduate students and post-graduate researchers, provides an introduction to Lie algebras and some of their applications to the spectroscopy of molecules, atoms, nuclei and hadrons. In the first part, a concise exposition is given of the basic concepts of Lie algebras, their representations and their invariants. The second part contains a description of how Lie algebras are used in practice in the treatment of bosonic and fermionic systems. Physical applications considered include rotations and vibrations of molecules (vibron model), collective modes in nuclei (interacting boson model), the atomic shell model, the nuclear shell model, and the quark model of hadrons. One of the key concepts in the application of Lie algebraic methods in physics, that of spectrum generating algebras and their associated dynamic symmetries, is also discussed. The book contains many examples that help to elucidate the abstract algebraic definitions. It provides a summary of many formulas of practical interest, such as the eigenvalues of Casimir operators and the dimensions of the representations of all classical Lie algebras.
Liapunov Functions and Stability in Control Theory
Presents a modern and self-contained treatment of the Liapunov method for stability analysis, in the framework of mathematical nonlinear control theory. A Particular focus is on the problem of the existence of Liapunov functions (converse Liapunov theorems) and their regularity, whose interest is especially motivated by applications to automatic control.
Les fonctions sphinctériennes = Sphincter functions
This book on Sphincter functions provides an update on a very topical subject, urinary and anal incontinence. Divided into three parts, it first deals with fundamental aspects, whether anatomical, physiological or clinical. The explorations of the various urinary and anorectal functions are described with electrophysiological, manometric, urodynamic tests as well as imaging. The second part is devoted to the pathology with all the dysfunctions that we encounter in daily practice. Urinary and anal incontinence, dysuria and retention, neurological sphincter disorders, dysfunctions in pregnant women and children are discussed. The last part takes stock of treatments, whether pharmacological, rehabilitative or surgical. This work, which contains a considerable amount of information, will undoubtedly be of interest to many medical specialists (physicians in physical medicine and rehabilitation, neurologists, gastroenterologists, gynecologists, general practitioners, pediatricians), surgeons (urologists, gynecological surgeons, surgeons). digestive) whether they are in training or already involved in the management of perineal disability. Other health professionals will find reference material there (nurses, physiotherapists, midwives).
Les cancers ovariens = Ovarian cancers
Deals with ovarian cancers and their therapeutic management. Besides the epithelial tumors which are the most frequent, the rarer tumors, with attenuated malignancy, germ cells or of the ovarian stroma are also studied. Specialists from multiple backgrounds each deliver in their field the most recent knowledge on the fundamental aspects of the disease, its genetic, epidemiological and prognostic characteristics and its pathological peculiarities. Modern means of diagnosis are presented. The surgical technique, including laparoscopy, is detailed at the different stages of the disease. The therapeutic strategy aims to position the surgery and chemotherapy according to the stage. The current place of radiotherapy and isotopic therapies is indicated. Some more specific aspects are discussed, screening, lymph node dissection, the “second look”, intraperitoneal chemotherapy with or without hyperthermia, treatment of the elderly, monitoring after treatment… as well as the emergence of targeted therapies.



















