الصفحة 33
الصفحة 33
Lysosomes
This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases.
LRFD Bridge Design : Fundamentals and Applications
Examines and explains material from the 9th edition of the AASHTO LRFD Bridge Design Specifications, including deck and parapet design, load calculations, limit states and load combinations, concrete and steel I-girder design, bearing design, and more. With increased focus on earthquake resiliency, two separate chapters– one on conventional seismic design and the other on seismic isolation applied to bridges– will fully address this vital topic. The primary focus is on steel and concrete I-girder bridges, with regard to both superstructure and substructure design. / Includes several worked examples for a project bridge as well as actual bridges designed by the author / Examines seismic design concepts and design details for bridges / Presents the latest material based on the 9th edition of the LRFD Bridge Design Specifications / Covers fatigue, strength, service, and extreme event limit states / Includes numerous solved problems and exercises at the end of each chapter to illustrate the concepts presented
Loss and Damage from Climate Change : Concepts, Methods and Policy Options
Provides an authoritative insight on the Loss and Damage discourse by highlighting state-of-the-art research and policy linked to this discourse and articulating its multiple concepts, principles and methods. Written by leading researchers and practitioners, it identifies practical and evidence-based policy options to inform the discourse and climate negotiations. With climate-related risks on the rise and impacts being felt around the globe has come the recognition that climate mitigation and adaptation may not be enough to manage the effects from anthropogenic climate change.
Longevity and Frailty
Contained in this book are the outcome of a colloquium sponsored by Fondation IPSEN in which interdisciplinary perspectives were brought to bear on conceptual, empirical and clinical aspects of this relationship. The result is a unique, innovative and timely blend of papers on topics ranging from frailty concepts in animal models and early Homo sapiens, to documentation of progress in morbidity compression, on the relationships between frailty and impairments and inflammation, and perspectives on long-term health care needs in an aging world.
Longer Life and Healthy Aging
Focuses on theoretical issues and empirical findings related to trends and determinants of healthy aging, including factors related to "healthy longevity" of the oldest-old, aged 80 and over. The group is the most rapidly increasing elderly sub-population and is most likely to need assistance in daily living in all countries. Chapters include both longitudinal and cross-sectional data from North America, Europe, and Asia in country-specific studies and cross-national comparisons. Part I focuses on the definition, components, concepts, measurements, and determinants of healthy aging, and discusses the trends and patterns of disability and healthy life expectancy at the macro level. Part II addresses individual healthy aging, including its biological and socio-demographic aspects. Part III focuses on issues concerning the family and healthy aging, and Part IV explores formal and informal care for healthy aging through governmental policy interventions and community service programs.
Logging in Java with the JDK 1.4 Logging API and Apache log4j
In development scenarios where things can't be run in a debugger, or when you run the risk of masking the problem, logs are the greatest source of information about running a program. Pro Apache Log4j, Second Edition provides best practices guidelines and comprehensive coverage of the most recent release. Step by step, the book explains core concepts, from basic to advanced. Code samples are in Java and include guidelines for different application-specific needs. You'll also learn how to extend the API to write custom components and best practices for using the feature-rich log4j API. This book concludes with enterprise Java applications using log4j with JSP and J2EE.
Liquid separations with membranes : An introduction to barrier interference
On the level of a textbook a self-consistent approach to liquid separations with membranes is presented, contrasting equilibrium separations with the rate-controlling effects of barrier interference on mass transfer. As a corollary objective, an effort is made to observe context, factual and historical, when introducing concepts and applications of membrane separation science. Ordering principle is the formal structure of mass transfer across barriers, being construed of a driving force (allocated to the condition of the mixtures to be separated) and a barrier permeability (holding the keys to membrane selectivity). The membranes, by this approach, appear by way of the mass transport demands which they are to meet, or else by way of the separation effects which they inspire.
Linear Systems Control : Deterministic and Stochastic Methods
Modern control theory and in particular state space or state variable methods can be adapted to the description of many different systems because it depends strongly on physical modeling and physical intuition. The laws of physics are in the form of differential equations and for this reason, this book concentrates on system descriptions in this form. This means coupled systems of linear or nonlinear differential equations. The physical approach is emphasized in this book because it is most natural for complex systems. It also makes what would ordinarily be a difficult mathematical subject into one which can straightforwardly be understood intuitively and which deals with concepts which engineering and science students are already familiar.
Linear Partial Differential Equations for Scientists and Engineers
This significantly expanded fourth edition is designed as an introduction to the theory and applications of linear PDEs. The authors provide fundamental concepts, underlying principles, a wide range of applications, and various methods of solutions to PDEs. In addition to essential standard material on the subject, the book contains new material that is not usually covered in similar texts and reference books, including conservation laws, the spherical wave equation, the cylindrical wave equation, higher-dimensional boundary-value problems, the finite element method, fractional partial differential equations, and nonlinear partial differential equations with applications.
Linear Functional Analysis
This introduction to the ideas and methods of linear functional analysis shows how familiar and useful concepts from finite-dimensional linear algebra can be extended or generalized to infinite-dimensional spaces. Aimed at advanced undergraduates in mathematics and physics, the book assumes a standard background of linear algebra, real analysis (including the theory of metric spaces), and Lebesgue integration, although an introductory chapter summarizes the requisite material. The initial chapters develop the theory of infinite-dimensional normed spaces, in particular Hilbert spaces, after which the emphasis shifts to studying operators between such spaces. Functional analysis has applications to a vast range of areas of mathematics; the final chapters discuss the particularly important areas of integral and differential equations.
Lighting Design Basics, 3rd ed.
Offering fundamental concepts and prescriptive techniques in a highly visual format, this book provides clear, practical guidance on utilizing the latest in lighting techniques and technology to showcase a space without sacrificing utility. Covering more than 25 different design scenarios with in-depth rationale for proposed solutions, this book provides insightful distribution diagrams, floor plans, and details for lighting installation and construction. Real-world case studies illustrate lighting design in residential, commercial, healthcare, education, and hospitality settings, and skill-building exercises offer practice for real-world projects as well as NCIDQ and NCARB exam preparation.
Lifestyle nursing
Examines the concepts of lifestyle medicine and nursing practice, it is specifically designed to help nurses introduce the concepts of lifestyle medicine to readers while also encouraging them to focus on their own wellness. This book features nutritional guidelines and supplemental materials operationalizing this basic nutrition knowledge into personal and patient wellness. It addresses evidence-based findings of chronic diseases including heart diseases and stroke, type 2 diabetes, and cancers, which can often be prevented by lifestyle interventions.
Lie Theory Vol.229 : Unitary Representations and Compactifications of Symmetric Spaces
It focuses on two fundamental questions in the theory of semisimple Lie groups: the geometry of Riemannian symmetric spaces and their compactifications; and branching laws for unitary representations, i.e., restricting unitary representations to (typically, but not exclusively, symmetric) subgroups and decomposing the ensuing representations into irreducibles.Ji's introductory chapter motivates the subject of symmetric spaces and their compactifications with carefully selected examples. A discussion of Satake and Furstenberg boundaries and a survey of the geometry of Riemannian symmetric spaces in general provide a good background for the second chapter, namely, the Borel–Ji authoritative treatment of various types of compactifications useful for studying symmetric and locally symmetric spaces. Borel–Ji further examine constructions of Oshima, De Concini, Procesi, and Melrose, which demonstrate the wide applicability of compactification techniques. Kobayashi examines the important subject of branching laws. Important concepts from modern representation theory, such as Harish–Chandra modules, associated varieties, microlocal analysis, derived functor modules, and geometric quantization are introduced. Concrete examples and relevant exercises engage the reader.
Lie Algebras and Applications
This book, designed for advanced graduate students and post-graduate researchers, provides an introduction to Lie algebras and some of their applications to the spectroscopy of molecules, atoms, nuclei and hadrons. In the first part, a concise exposition is given of the basic concepts of Lie algebras, their representations and their invariants. The second part contains a description of how Lie algebras are used in practice in the treatment of bosonic and fermionic systems. Physical applications considered include rotations and vibrations of molecules (vibron model), collective modes in nuclei (interacting boson model), the atomic shell model, the nuclear shell model, and the quark model of hadrons. One of the key concepts in the application of Lie algebraic methods in physics, that of spectrum generating algebras and their associated dynamic symmetries, is also discussed. The book contains many examples that help to elucidate the abstract algebraic definitions. It provides a summary of many formulas of practical interest, such as the eigenvalues of Casimir operators and the dimensions of the representations of all classical Lie algebras.
Les techniques de monitorage hémodynamique en réanimation = Hemodynamic monitoring techniques in intensive care
The hemodynamic monitoring of intensive care patients is undergoing major changes. Technological advances such as computerization and miniaturization have made it possible to considerably expand the range of assessment tools available at the bedside. Thus, the approach to cardiovascular monitoring - which was once readily "invasive" and global - is gradually becoming non-invasive and locoregional or even tissue. At the same time, the combined evolution of technology and physiological and pathophysiological concepts now provides the clinician with access to a variety of "functional hemodynamic monitoring". The aim of this book is to provide a better understanding of the interest and the limits of the hemodynamic parameters accessible by current hemodynamic monitoring techniques. It thus aims to ensure that the use of these techniques is perfectly mastered by resuscitators and anesthetists-resuscitators so that patient care is ultimately optimal.
Lectures on Algebraic Geometry I : Sheaves, Cohomology of Sheaves, and Applications to Riemann Surfaces
This book and the following second volume is an introduction into modern algebraic geometry. In the first volume the methods of homological algebra, theory of sheaves, and sheaf cohomology are developed. These methods are indispensable for modern algebraic geometry, but they are also fundamental for other branches of mathematics and of great interest in their own.In the last chapter of volume I these concepts are applied to the theory of compact Riemann surfaces. In this chapter the author makes clear how influential the ideas of Abel, Riemann and Jacobi were and that many of the modern methods have been anticipated by them.
Lean Architecture : Excellence in Project Delivery
Shows readers a path to improve their project delivery via the application of lean concepts and process management. Authors Michael Czap and Gregory Buchanan challenge readers to reexamine their approach to architectural practice and projects by presenting a unique and compelling alternative. Readers will learn to: Maximize the use of their resources to deliver superior results in less time / Minimize waste, cost, and inefficiency in their firm’s operations / Move between radically different project scales while retaining efficient and effective processes
Launching the imagination : A comprehensive guide to two-dimensional design
Launching the Imagination treats design as both a verb and a noun—as both a process and a product. Through an immersion in 2D, 3D, and 4D concepts and possibilities, students develop visual thinking strategies that will serve them throughout their studies and their careers. They discover that design is deliberate—a process of exploring a wide range of solutions and choosing the most promising option for development. They are encouraged to analyze each resulting solution thoughtfully in order to produce the clearest and most inventive solution to each assignment.
Laser-Tissue Interactions : Fundamentals and Applications
This essential work provides a thorough description of the fundamentals and applications in the field of laser-tissue interactions. Concepts such as the optical and thermal properties of tissue, and optical breakdown and its related effects, are treated in detail.
Lasers in dentistry—current concepts ; 2nd ed.
Provides information on the basic science and tissue interactions of dental lasers and documents the principal current clinical uses of lasers in every dental discipline. The applications of lasers in restorative dentistry, endodontics, dental implantology, pediatric dentistry, periodontal therapy, and soft tissue surgery are clearly described and illustrated. Information is also provided on laser-assisted multi-tissue management, covering procedures such as crown lengthening, gingival troughing, gingival recontouring, and depigmentation.
