الصفحة 323
الصفحة 323
Acute Myelogenous Leukemia
The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.
Acute Endocrinology : From Cause to Consequence
The integration of endocrinology in critical care medicine has led to new experimental and clinical data on the complex endocrine and metabolic derangements accompanying non-endocrine severe illnesses. The joining of these two disciplines has generated important novel insights with significant clinical implications. Acute Endocrinology: From Cause to Consequence compiles these new findings into an important and highly relevant new resource.
Actors and the Art of Performance : Under Exposure
Actors and the Art of Performance: Under Exposure combines the author's two main biographical paths: her professional commitment to the fields of both theatre and philosophy. The art of acting on stage is analysed here not only from the theoretical perspective of a spectator, but also from the perspective of the actor. The author draws on her experience as both a theatre actor and a university professor whose teachings in the art of acting rely heavily on her own experience and also on her philosophical knowledge. The book is unique not only in terms of its content but also in terms of its style. Written in a multiplicity of voices, the text oscillates between philosophical reasoning and narrative forms of writing, including micro-narratives, fables, parables, and inter alia by Carroll, Hoffmann and Kleist. Hence the book claims that a trans-disciplinary dialogue between the art of acting and the art of philosophical thinking calls for an aesthetical research that questions and begins to seek alternatives to traditionally established and ingrained formats of philosophy.
Active Rheology Control of Cementitious Materials
The research presented here develops a new method of actively controlling the rheology of fresh concrete during casting operations by incorporating specially designed responsive components. This results in real-time changes to the rheological behaviour of the cementitious material, allowing the user to intervene actively after the cementitious material has left the mixing phase. This newly gained agility contributes to increased processing speed and placement reliability in the case of traditional casting methods and can also facilitate advanced 3D concrete printing. The different routes followed to achieve this Active Rheology Control are explained within.
Active Knowledge Modeling of Enterprises
An AKM solution is about exploiting the Web as a knowledge engineering medium, and developing knowledge-model-based families of platforms, model-configured workplaces and services.
Active Flow Control ; Papers contributed to the Conference “Active Flow Control 2006”, Berlin, Germany, September 27 to 29, 2006
This volume contains a well balanced combination of theoretical and experimental state-of-the-art results of Active Flow Control. It combines new developments in actuator technology, sensing, robust and optimal open- and closed-loop control and model reduction for control. Numerical and experimental applications are considered from aeronautics, turbo-machinery and combustors.
Action Research in Software Engineering: Theory and Applications
This book addresses action research (AR), one of the main research methodologies used for academia-industry research collaborations. It elaborates on how to find the right research activities and how to distinguish them from non-significant ones. Further, it details how to glean lessons from the research results, no matter whether they are positive or negative. Lastly, it shows how companies can evolve and build talents while expanding their product portfolio.
Action and Responsibility
What makes an event count as an action? Typical answers appeal to the way in which the event was produced: e.g., perhaps an arm movement is an action when caused by mental states (in particular ways), but not when caused in other ways. Andrew Sneddon argues that this type of answer, which he calls "productionism", is methodologically and substantially mistaken. In particular, productionist answers to this question tend to be either individualistic or foundationalist, or both, without explicit defence.
Actin-Binding Proteins and Disease
This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.
Across the Sahara : Tracks, trade and cross-cultural exchange in Libya
Provides a multi-perspective approach to the caravan trade in the Sahara during the 19th century. Based on travelogues from European travelers, recently found Arab sources, historical maps and results from several expeditions, the book gives an overview of the historical periods of the caravan trade as well as detailed information about the infrastructure which was necessary to establish those trade networks.
Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma : Complication of Long-Term Dialysis
I have been involved in the treatment of chronic renal insuf? new and unexpected pathological conditions have also appeared as complications of long-term dialysis. One of these involves polycystic changes and their malignant transformation in diseased kidneys. Since I have studied these polycystic changes and their malignant transformation for many years, I decided to compile the results of my work in a book. Such conditions of diseased kidneys pose serious problems, particularly in Japan, where renal transplantation is performed very infrequently compared with other countries, and a large number of patients are managed by dialysis over a long period.
Acoustics for Engineers : Troy Lectures
Provides the material for an introductory course in engineering acoustics for students with basic knowledge in mathematics. It is based on extensive teaching experience at the university level. Under the guidance of an academic teacher it is sufficient as the sole textbook for the subject.
Acoustics and Sound Insulation : Principles, Planning, Examples
Provides expert planners and architects but also interested developers with practical knowledge on the subject of acoustics in high-rise architecture, beginning with standards on methods of planning and prognosis and moving on to the areas of acoustics of rooms and architecture and noise protection in urban planning. Presents typologically specific acoustic and soundproofing measures. Practical knowledge about acoustics in architecture, and noise protection in urban planning, as well as methods for planning and prognosis. Examples of built projects
Acoustic sensing techniques for the shallow water environment : Inversion methods and experiments
Contains the collection of papers from the second workshop on Experimental Acoustic Inversion Techniques for Exploration of the Shallow Water Environment. Acoustic techniques provide the most effective means for remote sensing of ocean and sea floor processes, and for probing the structure beneath the sea floor. No other energy propagates as efficiently in the ocean: radio waves and visible light are severely limited in range because the ocean is a highly conductive medium. However, sound from breaking waves and coastal shipping can be heard throughout the ocean, and marine mammals communicate acoustically over basin scale distances.
Acoustic MIMO Signal Processing
Telecommunication systems and human-machine interfaces start employing multiple microphones and loudspeakers in order to make conversations and interactions more lifelike, hence more efficient. This development gives rise to a variety of acoustic signal processing problems under multiple-input multiple-output (MIMO) scenarios, encompassing distant speech acquisition, sound source localization and tracking, echo and noise control, source separation and speech dereverberation, and many others. The last decade has witnessed a growing interest in exploring these problems, but there has been little effort to develop a theory to have all these problems investigated in a unified framework. This unique book attempts to fill the gap.
Acid in the Environment : Lessons Learned and Future Prospects
This book is the result of a conference held biannually at the Goodwin-Niering Center for Conservation Biology and Environmental Studies at Connecticut College.is a collection of essays that blends the research findings and the policy analyses of individuals from different academic disciplines with the positions advanced by representatives of NGOs. Acid in the Environment: Lessons Learned and Future Prospects presents a broad approach to the study of acid deposition, exposing readers with a scientific background to significant policy issues and those with a policy orientation to important ecological impacts. The book raises important questions that will serve as a springboard for discussion between diverse groups of teachers and students, concerned citizens and legislators, and scientists and policy makers.
Achieving the Paris Climate Agreement goals ; Part 2 : Science-based target setting for the finance industry — Net-Zero Sectoral 1.5˚C pathways for real economy sectors
Provides an in-depth analysis of industry sectors globally, and its purpose is to present emission reduction targets in 5-year steps (2025 to 2050) for the main twelve finance sectors per the Global Industry Classification System. This scientific analysis aims to support the United Nations Principles for Responsible Investment initiative to give sustainability guidance for the global finance industry. The industry sector pathways presented here are based on the latest global and regional 100% renewable energy and non-energy greenhouse gas Representative Concentration Pathways in order to keep climate change significantly under +1.5 C and thereby achieve the Paris Climate Agreement goals. The heart of this book is three chapters presenting the results of industry scenario modelling. These chapters cover twelve industry and service sectors as well as transportation and buildings. The specific energy demand and specific emissions are presented based on the emission accounting concept of “Scope 1, Scope 2 and Scope 3” emission pathways. This methodology has been developed to measure the climate and sustainability index for companies, and this research project expands the methodology to apply it to entire industry sectors ...
Achieving Excellence in Medical Education
Excellence in Medical Education explores the essential question facing medical educators and learners today: What is our vision of educational excellence, and what can we do to enhance our performance?
Accounting for deferred income taxes
Incorporates the new tax rates and other impacts of the Tax Cuts and Jobs Act and will assist you in understanding FASB ASC 740, Income Taxes, and how it establishes guidelines for accounting for income taxes, including income tax expense, classification of deferred tax accounts, and related disclosures.
Accounting for business : Practicalities and strategies
Identifies the types of organizations that generate financial information and explains how you can use it for your benefit. The early chapters focus on the information that is publicly available for large companies and demonstrate how to select and analyze the figures for decision making. The later chapters concentrate on the detailed management accounting information that is available internally for managers so that they can make decisions, investigate problems, and set performance targets. The final chapter, explores emerging and very pertinent issues such as "Can the organization obtain the basic resources to stay in business?" and "Are its activities harmful to the environment??
