الصفحة 32
الصفحة 32
An introduction to description logics
Designed so that domain knowledge can be described and so that computers can reason about this knowledge. DLs have recently gained increased importance since they form the logical basis of widely used ontology languages, in particular the web ontology language OWL. Written by four renowned experts, this is the first textbook on description logics. It is suitable for self-study by graduates and as the basis for a university course. Starting from a basic DL, the book introduces the reader to their syntax, semantics, reasoning problems and model theory and discusses the computational complexity of these reasoning problems and algorithms to solve them.
An Introduction To Chemoinformatics
This, the first text written specifically for this field, aims to provide an introduction to the major techniques of chemoinformatics. The first part of the book deals with the representation of 2D and 3D molecular structures, the calculation of molecular descriptors and the construction of mathematical models. The second part describes other important topics including molecular similarity and diversity, the analysis of large data sets, virtual screening, and library design. Simple illustrative examples are used throughout to illustrate key concepts, supplemented with case studies from the literature.
Amino acid biosynthesis : Pathways, regulation and metabolic engineering
Amino Acids Biosynthesis presents the current knowledge of fundamental as well as applied microbiology of amino acids. Topics discussed are the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The characterization of the control mechanisms of amino acid biosynthesis has revealed insights into principles of genetic and biochemical regulation, such as transcriptional regulators and a new class of regulatory elements, the riboswitch. The volume further deals with the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and, particularly, as food and feed additives.
Ambient intelligence : A novel paradigm
Ambient Intelligence (AmI) is an integrating technology for supporting a pervasive and transparent infrastructure for implementing smart environments. Such technology is used to enable environments for detecting events and behaviors of people and for responding in a contextually relevant fashion. AmI proposes a multi-disciplinary approach for enhancing human machine interaction. The authors start with a description of the iDorm as an example of a smart environment conforming to the AmI paradigm, and introduces computer vision as an important component of the system. Other computer vision examples describe visual monitoring for the elderly, classic and novel surveillance techniques using clusters of cameras installed in indoor and outdoor application domains, and the monitoring of public spaces. Face and speech recognition systems are also covered as well as enhanced LEGO blocks for novel educational purposes. The book closes with a provocative chapter on how a cybernetic system can be designed as the backbone of a human machine interaction.
Alternative Splicing and Disease
Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.
Altering nature ; Vol.1 : Concepts of ‘Nature’ and ‘The Natural’ in Biotechnology Debates
Volume One, Concepts of 'Nature' and 'The Natural' in Biotechnology Debates, offers nuanced accounts of the ways that nature is invoked and interpreted, both descriptively and prescriptively, by different disciplines, including perspectives from spirituality and religion, philosophy, science and medicine, law and economics, and aesthetics. In the context of that broad discussion.
Allosteric Regulatory Enzymes
This book provides a logical introduction to the limits for enzyme function as dictated by the factors that are limits for life. This book presents a complete description of all the mechanisms used for changing enzyme acticity. Eight enzymes are used as model systems after extensive study of their mechanisms. Wherever possible, the human form of the enzyme is used to illustrate the regulatory features.
Algorithms in Bioinformatics : Theory and Implementation
Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results
AJCC Atlante per la stadiazione dei tumori maligni = Atlas for the Staging of Malignant Tumors
he atlas contains over 400 specially created black and white illustrations describing the anatomical extent of the malignant tumor in the primary site (T), regional lymph nodes (N) and distant metastases (M) for various sites, including the head and neck area, the digestive system, the thorax, the musculoskeletal system, the soft tissues, the breast, the urinary system and the genital system. Each illustration provides precise and detailed descriptions designed to clarify the crucial anatomical structures and to provide the reader with an immediate view of the progressive extension of the disease. The most important anatomical structures are identified by specific definitions.
Ajax Patterns and Best Practices
Ajax is taking us into the next generation of web applications. Ajax has broken the client-server barrier by decoupling the client from the server, but an Ajax application still needs a server to extract content from. The most effective use of Ajax and the server requires an understanding of REST, an architectural style used to define Web services. Ajax Patterns and Best Practices explores dynamic web applications that combine Ajax and REST as a single solution. A major advantage of REST is that, like Ajax, it can be used with today's existing technologies.
Ajax in Oracle JDeveloper
The book covers web search and RSS Feed with Ajax as well as form validation with Ajax frameworks for Java, JSP, JSF, and PHP. It discusses using Ajax in Oracle JDeveloper and is IDE based. JDeveloper has the following advantages over Eclipse IDE.
Air-Ice-Ocean Interaction : Turbulent Ocean Boundary Layer Exchange Processes
At a time when the polar regions are undergoing rapid and unprecedented change, understanding exchanges of momentum, heat and salt at the ice-ocean interface is critical for realistically predicting the future state of sea ice. By offering a measurement platform largely unaffected by surface waves, drifting sea ice provides a unique laboratory for studying aspects of geophysical boundary layer flows that are extremely difficult to measure elsewhere. This book draws on both extensive observations and theoretical principles to develop a concise description of the impact of stress, rotation, and buoyancy on the turbulence scales that control exchanges between the atmosphere and underlying ocean when sea ice is present. Several interesting and unique observational data sets are used to illustrate different aspects of ice-ocean interaction ranging from the impact of salt on melting in the Greenland Sea marginal ice zone, to how nonlinearities in the equation of state for seawater affect mixing in the Weddell Sea.
Age-related changes of the human Eye
In Age-Related Changes of the Human Eye, the authors review all aspects of human eye aging. In addition to descriptions of age-related changes in almost all the structures of the human eyes, the authors also include interesting accounts of personal experiments and data.
Advances in web intelligence ; 1st International symposium, ISVC 2005, Lake Tahoe, NV, USA, December 5-7, 2005, proceedings
In recent years the Internet has become a source of data and information of indisputable importance and has immensely gained in acceptance and popularity. The World Wide Web (WWW or Web, for short), frequently named “the nervous system of the infor- tion society,” offers numerous valuable services leaving no doubt about the signi?cance of the Web in our daily activities at work and at home. Consequently, we have a clear aspiration to meet the obvious need for effective use of its potential by making - provements in both the methods and the technology applied. Among the new research directions observable in Web-related applications, intelligent methods from within the broadly perceived topic of soft computing occupy an important place. AWIC, the “Atlantic Web Intelligence Conferences” are intended to be a forum for exchange of new ideas and novel practical solutions in this new and exciting ?eld.
Advances in systems, computing sciences and software engineering ; Proceedings of SCSS 2005
Advances in Systems, Computing Sciences and Software Engineering This book includes the proceedings of the International Conference on Systems, Computing Sciences and Software Engineering (SCSS'05). The proceedings are a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of computer science, software engineering, computer engineering, systems sciences and engineering, information technology, parallel and distributed computing and web-based programming.
Advances in Molecular Oncology
Proceedings of the 2nd Annual IFOM-IEO Meeting on Cancer. This is a new meeting, it has about 200 attendees from Australia, Austria, Belgium, Brazil, Canada, England, France, Germany, Greece, Ireland, Italy, Japan, Netherlands, Spain, Sweden, Switzerland, and the USA. The 2nd IFOM-IEO international meeting on cancer will provide a forum in which the world’s leading cancer researchers and young scientists will discuss the latest advances in molecular oncology. The impact of recent breakthroughs in basic research and of emerging technologies on molecular medicine in cancer will be highlighted.
Advances in Mobile and Wireless Communications : Views of the 16th IST Mobile and Wireless Communication Summit
This Volume presents the most exciting results of the Mobile and Wireless Communication Summit, held 2007 in Budapest. It contains worked out contributions from all areas of wireless communications, physical layer, access methods, techniques and technologies, networks, applications and systems.
Advances in Mass Data Analysis of Signals and Images in Medicine, Biotechnology and Chemistry ; International Conference, MDA 2006/2007, Leipzig, Germany, July 18, 2007, Selected Papers
The automatic analysis of images and signals in medicine, biotechnology, and chemistry is a challenging and demanding field. Signal-producing procedures by microscopes, spectrometers, and other sensors have found their way into wide fields of medicine, biotechnology, economy, and environmental analysis. With this arises the problem of the automatic mass analysis of signal information. Signal-interpreting systems which generate automatically the desired target statements from the signals are therefore of compelling necessity. The continuation of mass analyses on the basis of classical procedures leads to investments of proportions that are not feasible. New procedures and system architectures are therefore required. The goals of this: Provide a forum for identifying important contributions and opportunities for research on mass data analysis on microscopic images Promote the systematic study of how to apply automatic image analysis and interpretation procedures to that field Show case applications of mass data analysis in biology, medicine, and chemistry Topics of interest include (but are not limited to): Techniques and developments of signal and image producing procedures Object matching and object tracking in microscopic and video microscopic images 1D, 2D, and 3D shape analysis and description
Advances in Learning Classifier Systems ; 4th International Workshop, IWLCS 2001, San Francisco, CA, USA, July 7-8, 2001. Revised Papers
The Fourth International Workshop on Learning Classifier Systems (IWLCS2001) was held July 7-8, 2001, in San Francisco, California, during the Geneticand Evolutionary Computation Conference (GECCO 2001). We have includedin this volume revised and extended versions of eleven of the papers presentedat the workshop.The volume is organized into two main parts. The first is dedicated to importanttheoretical issues of learning classifier systems research including the influenceof exploration strategy, a model of self-adaptive classifier systems, and the useof classifier systems for social simulation. The second part contains papers dis-cussing applications of learning classifier systems such as data mining, stocktrading, and power distribution networks.An appendix contains a paper presenting a formal description of ACS, a rapidlyemerging learning classifier system model.
Advances in decision making under risk and uncertainty
Whether we like it or not we all feel that the world is uncertain. From choosing a new technology to selecting a job, we rarely know in advance what outcome will result from our decisions. Unfortunately, the standard theory of choice under uncertainty developed in the early forties and fifties turns out to be too rigid to take many tricky issues of choice under uncertainty into account. The good news is that we have now moved away from the early descriptively inadequate modeling of behavior. This book brings the reader into contact with the accomplished progress in individual decision making through the most recent contributions to uncertainty modeling and behavioral decision making. It also introduces the reader into the many subtle issues to be resolved for rational choice under uncertainty.
