الصفحة 32
الصفحة 32
Geographic information metadata for spatial data infrastructures : Resources, interoperability and information retrieval
Metadata play a fundamental role in both DLs and SDIs. Commonly defined as "structured data about data" or "data which describe attributes of a resource" or, more simply, "information about data", it is an essential requirement for locating and evaluating available data. Therefore, this book focuses on the study of different metadata aspects, which contribute to a more efficient use of DLs and SDIs. The three main issues addressed are: the management of nested collections of resources, the interoperability between metadata schemas, and the integration of information retrieval techniques to the discovery services of geographic data catalogs (contributing in this way to avoid metadata content heterogeneity).
Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases
Improved understanding of role of protein dysmetabolism in neurodegeneration promises to improve diagnoses, facilitate the development of biological markers relevant to disease pathophysiology, and provide tractable therapeutic targets. This Fondation IPSEN conference summary provides an update on the latest advances of the role of protein misfolding in the pathophysiology of neurodegenerative diseases.
Genomic intelligence : Metagenomics and artificial intelligence
The field of metagenomics has revolutionized our comprehension of microbial diversity and function across various habitats, from the human body to terrestrial and aquatic environments. Simultaneously, advancements in AI have empowered researchers to analyze vast troves of genomic data with unprecedented speed and precision, facilitating new insights into the complex interplay between microorganisms and their surroundings. Provides an overview of metagenomics and discusses the combination of metagenomics and AI and its significant consequences for advancements in science. The chapters examine the approaches, difficulties, and revolutionary uses of AI in metagenomics and provide insight into the convergence of genomics, metagenomics, and AI’s potential to revolutionize diverse fields from healthcare to environmental.
Genomes and Genomics of Nitrogen-fixing Organisms
Inthe book the first section organism based and should review our current knowledge of the genomes of nitrogen-fixing organisms and what these nucleotide sequences tell us. The second section should then be technology based. It should review what technologies are available to mine the data inherent in the nucleotide sequences and how they are now being used to produce gene-function data from differential gene expression.
Genetics and regulation of nitrogen fixation in free-Living bacteria
This book is the second volume of a seven-volume series, which covers all fields of research related to nitrogen fixation - from basic studies through applied aspects to environmental impacts. Volume II provides a comprehensive and detailed source of information concerning the genetics and regulation of biological nitrogen fixation in free-living prokaryotes.
Genetics and Genomics of Soybean
The book covers recent progress on genome research in soybeans, including the genetic map with classical, RFLP, SSR and SNP markers; genomic and cDNA libraries, functional genomics platforms (e.g., cDNA, Affymetrix and oligonucleotide based DNA microarrays); physical maps, and the efforts to fully sequence the genome. Given the pending release of the soybean genome sequence, through the efforts of the Department of Energy’s Joint Genome Institute, this book will stand as a critical source of information on soybean.
Genetic programming IV : Routine human-competitive machine intelligence
Genetic Programming IV: Routine Human-Competitive Machine Intelligence presents the application of GP to a wide variety of problems involving automated synthesis of controllers, circuits, antennas, genetic networks, and metabolic pathways. The book describes fifteen instances where GP has created an entity that either infringes or duplicates the functionality of a previously patented 20th-century invention, six instances where it has done the same with respect to post-2000 patented inventions, two instances where GP has created a patentable new invention, and thirteen other human-competitive results. The book additionally establishes: GP now delivers routine human-competitive machine intelligence GP is an automated invention machine GP can create general solutions to problems in the form of parameterized topologies GP has delivered qualitatively more substantial results in synchrony with the relentless iteration of Moore's Law
Genetic Engineering : Principles and Methods
Genetic Engineering: Principles and Methods presents state-of-the-art discussions in modern genetics and genetic engineering. Recent volumes have covered gene therapy research, genetic mapping, plant science and technology, transport protein biochemistry, and viral vectors in gene therapy, among many other topics.
Generative and transformational techniques in software engineering ; International Summer School, GTTSE 2005, Braga, Portugal, July 4-8, 2005. Revised Papers
This tutorial book presents an augmented selection of material presented at the International Summer School on Generative and Transformational Techniques in Software Engineering, GTTSE 2005. The book comprises 7 tutorial lectures presented together with 8 technology presentations and 6 contributions to the participants workshop.
Gene Therapy for Cancer
The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer. Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing number of obstacles. These obstacles include vector systems that do not reach systemic metastases, therapeutic genes with redundant mec- nisms allowing for cellular resistance, and toxicities in clinical trials leading to premature closure of these studies. Different tactics to overcome or circumvent these obstacles have catalyzed the development of a wide range of gene therapy approaches. Thus far, almost two-thirds of gene therapy trials have focused on cancer. This reflects the concept that gene therapy approaches for the treatment of cancer do not necessarily require long-term expression of the gene as is necessary for the treatment of primary genetic defects like hemophilia or juvenile diabetes.
Gastrointestinal malignancies
Details the advances in drug discovery and delivery and the present need for emerging technologies. Throughout the text new micro and nanofabrication techniques are described, including methods such as electrohydrodynamic processes, additive manufacturing, and microfluidics, which have the potential to produce drug delivery systems that were not possible a few years ago. This book is of great use to both entry-level and experienced researchers in the field of emerging technologies for the manufacturing of drug delivery devices.
Galactose Regulon of Yeast : From Genetics to Systems Biology
The galactose regulon of yeast is one of the best studied regulons. It is an ideal paradigm for demonstrating fundamental and evolving concepts in biology and is used in this book as a model system to explain various facets of conventional and modern biology. The book starts with a brief historical overview on yeast research, i.e. early observations in enzyme adaptation, classical genetics, formulating hypotheses based on genetic inference. This is followed by molecular genetics of the galactose regulon, isolation of genes and testing of the hypotheses. The power of mutational analysis in deciphering molecular mechanisms is conveyed. Further, contemporary topics such as genomics, evolution, single cell analysis of transcriptional switching, binary and graded responses, biological consequences of feed back regulation in genetic circuits, and stochasticity are addressed.
Fungi as an Alternative Source of Anticancer and Antioxidant
Fungi are an " excellent but underexplored source " for new therapeutic compounds. The limited availability of bioactive principles in plant sources could be surpassed by exploiting the chemical entities in the endophytes fungi . fungi represent a rich source of bioactive metabolite that can manipulated to produce desirable novel analogs. In addition to the active substances that can be extracted from the fungi, so that they are useful in several mechanisms. Exploring and exploiting of metabolites from endophytic in terrestrial, mangrove and marine habitats may provide an avenue for discovery of drug candidates against deadly human disease. This review focuses on the production of antioxidant and anticancer from severa fungi habitats.
Fungal Genomics
Presents an overview on mutualistic and pathogenic interactions between fungi and plants. This book offers reviews on fungal lifestyles, mechanisms of their interactions with their host plants, signal perception and transduction, and plant defense responses directed against attack by fungal pathogens. It is suitable for students in microbiology.
Fundamentals of Radiation Materials Science : Metals and Alloys
adiation Materials Science teaches readers the fundamentals of the effects of radiation on metals and alloys. When energetic particles strike a solid, numerous processes occur that can change the physical and mechanical properties of the material. Metals and alloys represent an important class of materials that, by virtue of their use in nuclear reactor cores, are subject to intense radiation fields. Radiation causes metals and alloys to swell, distort, blister, harden, soften and deform. This textbook and reference covers the basics of particle-atom interaction for a range of particle types, the amount and spatial extent of the resulting radiation damage, the physical effects of irradiation and the changes in mechanical behavior of irradiated metals and alloys. Concepts are developed systematically and quantitatively, supported by examples, references for further reading and problems at the end of each chapter
Fundamentals of Pap Test Cytology
Fundamentals of Pap Test Cytology is intended as a practical primer on the Pap test. Using bold text, tables, and highlighted areas, this book offers readers a user-friendly text on Pap test fundamentals so readers may find specific information effortlessly. This book begins with a basic dictionary of terms, principles, and anatomy before detailing such issues as the Bethesda System, liquid-based and physiological cytology, reactive changes, human papillomavirus, and atypical squamous cells. The authors also discuss low-grade and high-grade squamous intra-epithelial lesions, invasive squamous carcinoma, endocervical and endometrial lesions, metastatic tumors, therapy-related changes, and the newest techniques in screening and managing Pap tests.
Fundamentals of fixed prosthodontics
A popular undergraduate text reflects research, materials, and techniques in fixed prosthodontics, with the addition of more than 350 new illustrations and three new chapters on the restoration of implants. It is designed to serve as an introduction to restorative dentistry techniques using fixed partial dentures and cast metal, metal-ceramic, and all-ceramic restorations, providing the background knowledge needed by the novice and serving as a refresher for the practitioner or graduate student.
Fundamental approaches to software engineering ; Vol. 3442 ; 8th International Conference, FASE 2005, Held as Part of the Joint European conferences on theory and practice of software, ETAPS 2005, Edinburgh, UK, April 4-8, 2005, Proceedings
ETAPS 2005 was the eighth instance of the European Joint Conferences on Theory and Practice of Software. ETAPS is an annual federated conference that was established in 1998 by combining a number of existing and new conf- ences. This year it comprised ?ve conferences (CC, ESOP, FASE, FOSSACS, TACAS), 17 satellite workshops (AVIS, BYTECODE, CEES, CLASE, CMSB, COCV, FAC, FESCA, FINCO, GCW-DSE, GLPL, LDTA, QAPL, SC, SLAP, TGC, UITP), seven invited lectures (not including those that were speci?c to the satellite events), and several tutorials. We received over 550 submissions to the ?ve conferences this year, giving acceptance rates below 30% for each one. The events that comprise ETAPS address various aspects of the system - velopment process, including speci?cation, design, implementation, analysis and improvement. The languages, methodologies and tools which support these - tivities are all well within its scope. Di?erent blends of theory and practice are represented, with an inclination towards theory with a practical motivation on the one hand and soundly based practice on the other. Many of the issues involved in software design apply to systems in general, including hardware s- tems,andtheemphasisonsoftwareisnotintendedtobeexclusive.
Fundamental approaches to software engineering ; 11th International Conference, FASE 2008, Held as Part of the Joint European conferences on theory and practice of software, ETAPS 2008, Budapest, Hungary, March 29-April 6, 2008. Proceedings
The fve main conferences received 571 submissions, 147 of which were accepted, giving an overall acceptance rate of less than 26%, with each conference below 27%.Congratulationsthereforetoallthe authorswhomadeittothe alprogramme! I hope that most of the other authors will still have found a way of participating in this exciting event, and that you will all continue submitting to ETAPS and contributing to make of it the best conference in the area،The events that comprise ETAPS address various aspects of the system velopment process,including specifcation, design, implementation, analysis and improvement.
Fundamental approaches to software engineering ; 10th International Conference, FASE 2007 Held as part of the joint European conference on theory and practice of software, ETAPS 2007 Braga, Portugal, March 24 - April 1, 2007 Proceedings
This book constitutes the refereed proceedings of the 10th International Conference on Fundamental Approaches to Software Engineering, FASE 2007, held in Braga, Portugal in March/April 2007 as part of ETAPS 2007, the Joint European Conferences on Theory and Practice of Software.
