الصفحة 30
الصفحة 30
Dynamics of soils and their engineering applications
Offers systematic dynamic analysis of soils and their engineering applications, including machine foundations, and aims to develop a clear understanding of the subject. It comprises sixteen chapters. Chapter 1 introduces the reader to the various problems in soil dynamics. In Chapter 2, concepts of theory of vibrations are discussed along with their applications in designing Vibration Absorbers and Pickups. Wave propagation in elastic medium including wave refraction in layered medium is covered in Chapter 3. Chapter 4 deals with the procedure of determining dynamic properties of soils using various laboratory and field tests. Dynamic earth pressures in retaining walls and dynamic bearing capacity of footings are dealt with in Chapters 5 and 6 respectively
Dynamics of Freezing-Thawing Soil around Subway Shield Tunnels
Addresses development laws for axial strain and excess pore water pressure in silty clay around subway shield tunnels before and after freezing-thawing when subjected to subway loading, as well as the effect of freezing-thawing on the dynamic parameters of silty clay, including the dynamic modulus and damping ratio, introducing readers to the design and construction of bypasses in subway tunnels with the artificial freezing method. On this basis, it then studies the microstructures of silty clay before and after freezing-thawing cyclic loading by means of scanning electron microscope tests and mercury intrusion porosimetry tests. Lastly, the book presents a numerical simulation of the dynamics of silty clay around subway tunnels before and after thawing.
Dynamic Trip Modelling : From Shopping Centres to the Internet
When I looked for a new application, I realised that shopping centre demand could be like a longitudinal wave, governed by centre opening and closing times. The testing and application of the model required the compilation of shopping centre surveys and an Internet data set.
Dynamic Regression Models for Survival Data
This book studies and applies modern flexible regression models for survival data with a special focus on extensions of the Cox model and alternative models with the aim of describing time-varying effects of explanatory variables.
Dynamic Magma Evolution
Understanding the magmatic processes responsible for the chemical and textural signatures of volcanic products and igneous rocks is crucial for monitoring, forecasting, and mitigating the impacts of volcanic activity. Dynamic Magma Evolution is a compilation of recent geochemical, petrological, physical, and thermodynamic studies. It combines field research, experimental results, theoretical approaches, unconventional and novel techniques, and computational modeling to present the latest developments in the field.
Dynamic Fleet Management : Concepts, Systems, Algorithms & Case Studies
Dynamic Fleet Management will focus on real time management of a distribution system. The book will integrate the latest results in system design, algorithm development and system implementation, to capture the state-of-the art research and application trends.
Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology
Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. This is assisting clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. In this book, targeted at both clinical practitioners and basic scientists, the principles of the methods, their practical implementation, and their application to specific tumor types are discussed by the leading authorities in the field today. The book will serve as an invaluable single-volume reference covering all the latest developments in contrast-enhanced oncological MRI.
Dynamic characterisation of analogue-to-digital converters
Dynamic Characterisation of Analogue-to-Digital Converters presents a state of the art overview of the methods and procedures employed for characterising ADCs’ dynamic performance behaviour using sinusoidal stimuli. The three classical methods – histogram, sine wave fitting, and spectral analysis – are thoroughly described, and new approaches are proposed to circumvent some of their limitations
Dynamic Assessment : A Vygotskian Approach to Understanding and Promoting L2 Development
This book presents the first in-depth analysis of DA’s application to particular problems of L2 development. It includes detailed discussions of the core theoretical tenets as well as guidelines for implementing DA principles in L2 classrooms. The book will be of interest to language teacher educators, language testers, classroom practitioners, and students and researchers in the areas of SLA, language pedagogy, and assessment.
Dynamic Analysis of Structures
Reflects the latest application of structural dynamics theory to produce more optimal and economical structural designs. The author includes carefully worked-out examples which are solved utilizing more recent numerical methods. These examples pave the way to more accurately simulate the behavior of various types of structures. The essential topics covered include principles of structural dynamics applied to particles, rigid and deformable bodies, thus enabling the formulation of equations for the motion of any structure.
Drying of Porous Materials
This book provides recent advances in research on drying of saturated particulates and porous materials. The present volume is based on the selected papers presented at the XI Polish Drying Symposium 2005. The selected contributions cover theoretical modeling as well as experimental research on heat and mass transfer in porous and multiphase media during drying. The comprehensiveness and profound treatment of the subject makes this book an excellent pioneering contribution to the science and technology of drying of particulate solids.
Drugs quality control (theoretical foundation and practical application) : The coursebook
Presents the basics of drugs quality control in accordance with regulatory documents (pharmacopoeia of Europe, USA, Japan, Russia) and new data from current scientific periodicals, monographs The features of the physical, spectral and chemical quality control of medicines according to the indicators «identification», «tests» and «assay» are described in detail. Part II presents a workbook, which includes questions for the self-control of the material studied and tasks for a laboratory workshop. The Course book contains reference material and samples of pharmacopoeial articles. The Course book is designed for students of the specialty «Pharmacy».
Drugs of abuse : Body fluid testing
The authors discuss the various body fluid specimens suitable for testing for illicit drugs describe the structural and manufacturing aspects of on-site testing devices based on lateral flow immunoassay, and detail the pitfalls sometimes encountered when using these specimens. They also discuss in detail the problem of sample adulteration and its detection. Political, social, and legal issues are also considered in articles on privacy, the use of drug testing in courts, and the problem of sample adulteration.
Drugs Compromising Male Sexual Health
This concise drug guide lists approximately 500 substances, such as pharmaceutical drugs, lifestyle drugs, and environmental toxicants, that show documented untoward effects on the male sexual organs and their functions.
Drug utilization research : Methods and applications
Drug Utilization Research (DUR) is a discipline which combines aspects of pharmacotherapy, epidemiology, and health services research into an interdisciplinary set of methods for analyzing and assessing the prescribing, dispensing and consumption of medicines. It combines both qualitative and quantitative approaches to facilitate the safe and effective use of pharmaceuticals. Drug Utilization Research: Methods and Applications provides a comprehensive introduction to this discipline, prepared by an international team of authors with broad experience in numerous fields. Now reorganized and updated to reflect the latest research and global challenges, it is an indispensable resource for understanding the use of pharmaceuticals.
Drug Testing in Alternate Biological Specimens
Drug Testing in Alternate Biological Specimens provides researchers and forensic toxicologists with a convenient general text summarizing the state of knowledge today.
Drug target selection and validation
Focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
Drug safety evaluation : Methods and protocols
Focuses on the most recent advances in the field of drug safety evaluation. Divided into seven parts, chapters detail specific aspects related to the experimental design of preclinical studies conducted to support the safety of pediatric and combination drugs, necropsy and histopathology evaluation, mass spectrometry imaging, genetic toxicology protocols including the Pig-a mutation assay, safety pharmacology methods such as automatization of patch-clamp procedures, target safety assessment for investigative toxicology, screening assays for developmental toxicology, and methods to characterize novel translational safety biomarkers like microRNAs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting to avoid known pitfalls.
Drug safety evaluation
Presents an all-inclusive practical guide for those who are responsible for developing new drugs and ensuring the safety of an ever-expanding spectrum of therapeutics. This book helps readers understand how the safety of these products are evaluated for use. Extensively revised to reflect up-to-date information, this edition includes changes to the scope of products (vaccines, small synthetic, large protein moieties, cells and tissues), harmonized global and national regulatory requirements, the therapeutic development process, and available technologies to identify and evaluate the relevance of potential patient risks
Drug discovery with privileged building Blocks : Tactics in medicinal chemistry
Drug Discovery with Privileged Building Blocks traces back PharmaBlock’s founding philosophy of designing privileged building blocks. High-quality building blocks are crucial not only to biological activities of different molecules but also to ADMET properties, which eventually will impact the success rate of drug discovery projects. A thorough study of how building blocks perform in drug molecules and a regular analysis of new building block structures in the latest researches have proven to be a fruitful strategy to generate novel building blocks. Using this strategy, PharmaBlock has supplied the drug industry with a great number of building blocks, which are increasingly being adopted by drug hunters, and these are identified in this book.
