New pharmacological hypothesis for cancer therapy and treatment
Despite the considerable development of new cancer drugs the mortality remains high and the improvement in survival rate remains poor compared to the number of new concepts of cancer therapy in which we will review in our study and we will focus on two possible reasons for that delay in success such as the limitation of diagnostic tools to perform early detection for the tumor in a stage where it can be well treated or even cured as it is often a silent disease in the start phase of it...
New metropolitan perspectives : Knowledge dynamics, innovation-driven policies towards the territories’ attractiveness ; Vol.1
This book presents the outcomes of the symposium “NEW METROPOLITAN PERSPECTIVES,” held at Mediterranea University, Reggio Calabria, Italy on May 26–28, 2020.
New Introduction to Multiple Time Series Analysis
This reference work and graduate level textbook considers a wide range of models and methods for analyzing and forecasting multiple time series. The models covered include vector autoregressive, cointegrated,vector autoregressive moving average, multivariate ARCH and periodic processes as well as dynamic simultaneous equations and state space models. Least squares, maximum likelihood and Bayesian methods are considered for estimating these models. Different procedures for model selection and model specification are treated and a wide range of tests and criteria for model checking are introduced. Causality analysis, impulse response analysis and innovation accounting are presented as tools for structural analysis. The book is accessible to graduate students in business and economics. In addition, multiple time series courses in other fields such as statistics and engineering may be based on it. Applied researchers involved in analyzing multiple time series may benefit from the book as it provides the background and tools for their tasks. It bridges the gap to the difficult technical literature on the topic.
New Horizons of Parallel and Distributed Computing
Parallel and distributed computing is one of the foremost technologies for shaping future research and development activities in academia and industry. Hyperthreading in Intel processors, hypertransport links in next generation AMD processors, multicore silicon in today’s high-end microprocessors, emerging cluster and grid computing, has moved parallel/distributed computing into the mainstream of computing. New Horizons of Parallel and Distributed Computing is a collection of self-contained chapters written by pioneers and researchers to provide solutions for newly emerging problems in this field. This volume will not only provide novel ideas, work in progress and state-of-the-art techniques in the field, but also stimulate future research activities in the area of parallel and distributed computing with applications. New Horizons of Parallel and Distributed Computing is intended for researchers and graduate students in computer science and electrical engineering, as well as researchers and developers in industry. This book can be used as a textbook and a reference for use by students, researchers, and developers.
New Frontiers in Enterprise Risk Management
This book provides introductory material about enterprise risk management, and the role of risk in decision making. It presents enterprise risk management from perspectives of finance, accounting, insurance, supply chain operations, and project management. Technology tools are addressed, to include financial models of risk as well as accounting aspects using data envelopment analysis, neural network tools for credit risk evaluation, and real option analysis applied to information technology outsourcing. Three chapters present enterprise risk management experience in China, to include banking, chemical plant operations, and information technology.
New Frontiers in Angiogenesis
New Frontiers in Angiogenesis starts with a comprehensive overview of the field and continues with topics that have been minimally explored. The topics deal with dynamics of vasculogenesis using imaging techniques, bone marrow-derived endothelial cell precursors as potential therapeutic tools, regulation of post-angiogenic vessel regression, vascular mimicry, design and construction of artificial vessels, bioengineering of angiogenesis, and lymphangiogenesis recapitulating angiogenesis in health and disease states. Each chapter is written by leading experts of the subjects. It is hoped that this volume will challenge all of us interested in the field of angiogenesis and cardiovascular biology, in particular those in academia and industries, to think "outside the box" and explore angiogenesis from a fresh angle. It is hoped that New Frontiers in Angiogenesis is thought provoking and serve as a road map for discovering new findings to help betterments of human health.
New Directions : Efficiency and Productivity
The key unifying conceptual tool of this important entry in the study of efficiency and productivity is the directional distance function. In New Directions the authors take up this new performance measure while also maintaining their ''traditional'' axiomatic production theoretic approach.
New diagnostic method th detect peritoneal metastases in colorectal cancer
Colorectal cancer is the third common reason of death in population worldwide therefore we will focus in our study about description of this type of cancer and its symptoms to raise the public awareness to go to the right specialist as soon as the symptoms appear to improve early detection of this disease and the overall survival and we will highlight the best diet and life style to avoid this type of cancer hopefully beside that we will present all the most successful therapies of this disease from different classes of compounds such as chemotherapy or anti angiogenic and Metformin and other bacterial therapy however the major goal of the experimental part of this research is performed to establish a new promising diagnostic tool by Near Infra-red camera after injection of indyocine green to detection the peritoneal metastasis of colorectal in 15 patients since this kind of metastasis
New Developments in Parsing Technology
Parsing can be defined as the decomposition of complex structures into their constituent parts, and parsing technology as the methods, the tools, and the software to parse automatically. Parsing is a central area of research in the automatic processing of human language. Parsers are being used in many application areas, for example question answering, extraction of information from text, speech recognition and understanding, and machine translation. New developments in parsing technology are thus widely applicable. This book contains contributions from many of today's leading researchers in the area of natural language parsing technology. The contributors describe their most recent work and a diverse range of techniques and results. This collection provides an excellent picture of the current state of affairs in this area. This volume is the third in a series of such collections, and its breadth of coverage should make it suitable both as an overview of the current state of the field for graduate students, and as a reference for established researchers.
New Corporate Governance: Successful Board Management Tools
it presents an innovative and integrated approach to the theory and practice of corporate governance. Central to this approach is a set of instruments - developed and tested by the author - that can be used by boards to offer effective strategic direction and control to their organizations. The board instruments can be readily applied to the targeted selection, review, remuneration and development of board members, and for conducting board self-evaluations. This new approach to corporate governance is based on four guiding principles: keep it situational, keep it strategic, keep it integrated, and keep it controlled. Together, these principles form the basis of an integrated approach that addresses all key aspects of corporate governance. The main arguments in each section are supported by conceptual models, practical board tools or case studies, making the book ideally suited to board members, senior managers and post-graduate students.
New Corporate Governance : Successful Board Management Tools
Martin Hilb presents an innovative and integrated approach to the theory and practice of corporate governance. Central to this approach is a set of instruments - developed and tested by the author - that can be used by boards to offer effective strategic direction and control to their organizations. The board instruments can be readily applied to the targeted selection, review, remuneration and development of board members, and for conducting board self-evaluations. This new approach to corporate governance is based on four guiding principles: keep it situational, keep it strategic, keep it integrated, and keep it controlled. Together, these principles form the basis of an integrated approach that addresses all key aspects of corporate governance. The main arguments in each section are supported by conceptual models, practical board tools or case studies, making the book ideally suited to board members, senior managers and post-graduate students.
New Concepts of Antiviral Therapy
Antiviral drugs are important tools for treatment or prevention of viral infections. These drugs were first used for monotherapy, but nowadays combinations of antiviral agents are often part of a standard treatment as evidenced by e.g. HAART (highly active antiretroviral therapy). However, in almost every case of antiviral therapy, drug resistant viruses appear. In addition, the low oral bioavailability, toxicity and the number of severe side effects still pose significant problems. All of the latter issues limit the clinical usefulness and drive the need for improved antiviral strategies. These strategies include new drugs and targets, novel modes of action, vector-based treatments and even the block of defined genes by inhibiting mRNA formation (siRNA).
New Business Models for the Reuse of Secondary Resources from WEEEs : The FENIX Project
This book summarizes research being pursued within the FENIX project, funded by the EU community under the H2020 programme, the goal of which is to design a new product service paradigm able to promote innovative business models, to open added value to the vessels and to create new market segments. It experiments and validates its approach on three new concepts of added-value specialized vessels able to run requested services for several maritime sectors in the most effective, efficient, economic valuable and eco-friendly way. The three vessels share the same lean design methodology, IoT tools and HPC simulation strategy: a lean fact-based design model approach, which combines real operative data at sea with lean methodology, to support the development and implementation of the vessel concepts; IT customized tools to enable the acquisition, processing and usage of on board and local weather data, through an IoT platform, to provide business services to different stakeholders; HPC simulation, providing a virtual towing tank environment, for early vessel design improvement and testing. The book demonstrates that an integrated LCC analysis and LCC strategy to guarantee sustainability to vessels concepts and the proper environmental attention inside the maritime industry.
New Algorithms, Architectures and Applications for Reconfigurable Computing
New Algorithms, Architectures and Applications for Reconfigurable Computing consists of a collection of contributions from the authors of some of the best papers from the Field Programmable Logic conference (FPL’03) and the Design and Test Europe conference (DATE’03).
New Algorithms for Macromolecular Simulation
Molecular simulation is a widely used tool in biology, chemistry, physics and engineering. This book contains a collection of articles by leading researchers who are developing new methods for molecular modelling and simulation. Topics addressed here include: multiscale formulations for biomolecular modelling, such as quantum-classical methods and advanced solvation techniques; protein folding methods and schemes for sampling complex landscapes; membrane simulations; free energy calculation; and techniques for improving ergodicity. The book is meant to be useful for practitioners in the simulation community and for those new to molecular simulation who require a broad introduction to the state of the art.
Neuroscribe = نيوروسكرايب
Neuroscribe is a cutting-edge deep learning framework designed to address the complexities and inefficiencies encountered in existing frameworks like PyTorch and TensorFlow. Aimed at streamlining model development and enhancing performance across diverse hardware environments, NeuroScribe offers a lightweight and flexible solution. The framework features a robust tensor library, an auto-differentiation engine, a comprehensive neural network module, and advanced optimization algorithms. With built-in visualization tools and a user-friendly interface, NeuroScribe simplifies both beginner and advanced workflows. Its cross-platform compatibility, supported by CUDA and Metal Performance Shaders (MPS), ensures optimal performance, and in some scenarios, NeuroScribe demonstrates superior speed compared to leading frameworks. Additionally, NeuroScribe introduces unique libraries and features not found in other frameworks, further enhancing its versatility and appeal. The modular architecture and automatic system detection further enhance its adaptability, making NeuroScribe a versatile and powerful tool for deep learning practitioners.
Neuro–Fuzzy Associative Machinery for Comprehensive Brain and Cognition Modelling
Neuro–Fuzzy Associative Machinery for Comprehensive Brain and Cognition Modelling" is a graduate–level monographic textbook. It represents a comprehensive introduction into both conceptual and rigorous brain and cognition modelling. It is devoted to understanding, prediction and control of the fundamental mechanisms of brain functioning. The reader will be provided with a scientific tool enabling him to perform a competitive research in brain and cognition modelling.
Neurodegeneration in Multiple Sclerosis
In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic reliability and to monitor the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy as to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMRI, and their application is dramatically changing our understanding of how MS causes irreversible disability.
Neurobiology of Human Values
Man has been pondering for centuries over the basis of his own ethical and aesthetic values. Until recent times, such issues were primarily fed by the thinking of philosophers, moralists and theologists, or by the findings of historians or sociologists relating to universality or variations in these values within various populations. Science has avoided this field of investigation within the confines of philosophy. Beyond the temptation to stay away from the field of knowledge science may also have felt itself unconcerned by the study of human values for a simple heuristic reason, namely the lack of tools allowing objective study. For the same reason, researchers tended to avoid the study of feelings or consciousness until, over the past two decades, this became a focus of interest for many neuroscientists
Neuroanatomy for the Neuroscientist
Neurology, more than any other system of medicine, is rooted in the firm knowledge of basic science material (i.e., the anatomy, physiology, and pathology of the nervous system). This material enables students to readily arrive at diagnoses and to apply their knowledge at solving problems in clinical situations. Neuroanatomy for the Neuroscientist gives neuroscientists the tools to teach this material at levels appropriate for students at several levels of study, including undergraduate, graduate, dental, and medical school. The text also provides an updated approach to lesion localization in neurology, utilizing the techniques of computerized axial tomography (CT scanning), magnetic resonance imaging (MRI), and magnetic resonance angiography (MRA). Multiple illustrations demonstrating the value of these techniques in clinical neurology and neuroanatomical localization has been provided.



















