الصفحة 3
الصفحة 3
Nanopharmaceuticals ; Vol.1 : Expectations and realities of multifunctional drug delivery systems
Reviews advances in the drug delivery field via nanovehicles or nanocarriers that offer benefits like targeted therapy and serves as a single dose magic bullet for multiple drug delivery with improved drug efficiency at a lower dose, transportation of the drug across physiological barriers as well as reduced drug-related toxicity. The chapters are written by a diverse group of international researchers from industry and academia. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.
Nanocatalysis
Nanocatalysis is one of the most exciting subfields to have emerged from nanoscience. Its central aim is the control of chemical reactions by changing the size, dimensionality, chemical composition and morphology of the reaction center and by changing the kinetics using nanopatterning of the reaction centers. This approach opens up new avenues for atom-by-atom design of nanocatalysts with distinct and tunable chemical activity, specificity, and selectivity. This book is intended to give a pedagogical and methodological overview of this exciting and growing field and to highlight specific examples of current research. In this way, it serves both as an instructive introduction for graduate students who plan to enter the field and as a reference work for scientists already active in this and related areas.
NanoBiotechnology : BioInspired Devices and Materials of the Future
NanoBioTechnology: BioInspired Devices and Materials of the Future is a groundbreaking text that will assist scientists and students in learning the fundamentals and cutting-edge nature of this new and emerging science. Focusing on materials and building blocks for nanotechnology, leading scientists from around the world share their knowledge and expertise in this authoritative volume. The volume is broken into five sections. The first section presents an overview of nanotechnology and describes the many aspects of the field. Section 2 details biological materials serving as nanotemplates for bottom-up fabrication. Section 3 covers the use of biological macromolecules for electron transfer and computation. Section 4 presents a brief overview of the extensive and rapidly growing field of nanomedicine. Finally, Section 5 details de-novo designed structures and the various approaches different scientific groups take with molecular level training and language
Multiwavelength Approach to Unidentified Gamma-Ray Sources : A 2nd Workshop on the Nature of the High-Energy Unidentified Sources
Nearly one half of the point-like gamma-ray sources detected by EGRET instrument of the late Compton satellite are still defeating our attempts at identifying them. To establish the origin and nature of these enigmatic sources has become a major problem of current high-energy astrophysics. The second workshop on Multiwavelength Approach to Unidentified Gamma-ray Sources intends to shed new and fresh light on the problem of the nature of these mysterious sources and the objects behind them. The proceedings contain 46 contributed papers in this subject, which cover theoretical models on gamma-ray sources as well as the best multiwavelength strategies for the identification of the promising candidates. The topics of this conference also include energetic phenomena ocurring both in galactic and extragalactic scenarios, phenomena that might lead to the appearance of what we have called high-energy unidentified sources. The book will be of interest for all active researchers in the high-energy astrophysics and related research areas as well as for scientists and graduate students interested in understanding the recent progress in this field.
Multivariate Statistical Machine Learning Methods for Genomic Prediction
This book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments.
Multiscale Modeling in Epitaxial Growth
Epitaxy is a very active area of theoretical research since several years. It is experimentally well-explored and technologically relevant for thin film growth. Recently powerful numerical techniques in combination with a deep understanding of the physical and chemical phenomena during the growth process offer the possibility to link atomistic effects at the surface to the macroscopic morphology of the film. The goal of this book is to summarize recent developments in this field, with emphasis on multiscale approaches and numerical methods. It covers atomistic, step-flow, and continuum models and provides a compact overview of these approaches. It also serves as an introduction into this highly active interdisciplinary field of research for applied mathematicians, theoretical physicists and computational materials scientists.
Multiple Bonds between Metal Atoms
The 3rd edition of the Multiple Bonds between Metal Atoms deals with one of the most active fields of inorganic chemistry … . It presents an extensive, critical review and discussion of preparations, reactions, bonding, and physical properties of more than 4000 compounds … heartily recommend it to inorganic and materials chemists, and to all scientists concerned with the synthesis, spectroscopy, and structures of transition-metal compounds. It also belongs in academic, industrial, and government research libraries.
Multimedia Encryption and Watermarking
Multimedia Encryption and Watermarking presents a comprehensive survey of contemporary multimedia encryption and watermarking techniques, which enable a secure exchange of multimedia intellectual property. Part I, Digital Rights Management (DRM) for Multimedia, introduces DRM concepts and models for multimedia content protection, and presents the key players. Part II, Multimedia Cryptography, provides an overview of modern cryptography, with the focus on modern image, video, speech, and audio encryption techniques. This book also provides an advanced concept of visual and audio sharing techniques. Part III, Digital Watermarking, introduces the concept of watermarking for multimedia, classifies watermarking applications, and evaluates various multimedia watermarking concepts and techniques, including digital watermarking techniques for binary images. Multimedia Encryption and Watermarking is designed for researchers and practitioners, as well as scientists and engineers who design and develop systems for the protection of digital multimedia content. This volume is also suitable as a textbook for graduate courses on multimedia security.
Multimedia computing systems and virtual reality
Presents recent advancements in multimedia systems as they relate to various application areas such as healthcare services and agriculture-related industries. The authors also discuss human-machine interface design, graphics modelling, rendering/animation, image/graphics techniques/systems and visualization. They then go on to explore multimedia content adaptation for interoperable delivery. Finally, the book covers cultural heritage, philosophical/ethical/societal/international issues, standards-related virtual technology and multimedia uses. This book is intended for computer engineers and computer scientists developing applications for multimedia and virtual reality and professionals working in object design and visualization, transformation, modelling and animation of the real world.
Multi-Arm Cooperating Robots : Dynamics and Control
This book will be useful to a wide audience of engineers, ranging from undergraduate and graduate students, new and advanced academic researchers, to practitioners (mechanical and electrical engineers, computer and system scientists). It is intended for readers whose work involves manufacturing, industrial, robotics, automation, computer and control engineering, and who wish to find out about this important new technology and its potential advantages for control engineering applications.
Mr Hopkins Men : Cambridge Reform and British Mathematics in the 19th Century
Tells the story of Hopkins and the education and subsequent careers of his top "wranglers", many of whom went on to have illustrious careers as bishops, judges, politicians, scientists or educators. It draws on first-hand accounts of life at Cambridge to give the reader a glimpse inside its colleges, and it charts the evolution of the curriculum and the slow, often reluctant, reforms that led to Cambridge’s dominance of British higher education. It surveys the scientific achievements of the time and considers the disproportionate contributions made by Scottish and Irish alumni in establishing a research community. Gradually, Cambridge was transformed from a near-moribund institution into a world-renowned centre for the mathematical and physical sciences.
Moving Millions : Transport Strategies for Sustainable Development in Megacities
The Alliance for Global Sustainability is an international partnership among four of the leading scienti?c and technological universities worldwide: • The Massachusetts Institute of Technology (MIT-AGS); • The University of Tokyo (UT); • The Swiss Federal Institute of Technology (ETH); and • The Chalmers University of Technology. Created in 1997, the AGS today brings together hundreds of university scientists, engineers, and social scientists to address complex issues that lie at the intersection of environmental, economic, and social policy goals. Since its inception, the AGS has promoted and supported multidisciplinary research teams drawn from its partner institutions. Working on critical issues in sustainability across several ?elds encompassing energy and climate, mobility, urban systems, water and agriculture, cleaner technologies, public policy, and communications, these teams have developed a signi?cant body of new knowledge.
Monograph of the Urostyloidea (Ciliophora, Hypotricha)
This monograph is the second of a series treating the hypotrichs, a major part of the spirotrichous ciliates. The urostyloids are characterised by a zigzag-arrangement of the ventral cirri. Like the first part of the series, the Oxytrichidae, it summarises the morphological, morphogenetic, faunistic, and ecological data from the past 230 years, scattered in more than 1300 references from all over the world. Dichotomous keys lead to 36 genera and subgenera comprising 153 species illustrated by more than 2100 figures, including original ones. The treatise offers taxonomists, cell biologists, and ecologists a thorough and up-to-date revision because for each species a detailed list of synonyms, a discussion of the nomenclature and systematics, and an extensive description of the morphology and ecology, including almost all published faunistic records, are provided. With the monographs of the Urostyloidea and the Oxytrichidae the interested scientist can identify more than 320 species of hypotrichs, which are an important component of the eukaryotic microbial life in limnetic, marine, and terrestrial habitats.
Molecular Paradigms of Infectious Disease : A Bacterial Perspective
This comprehensive volume, written by leading authors in the field, provides a fundamental understanding of the complex cellular and molecular processes that are important for bacterial virulence and the infectious disease process. Written in a clear and engaging manner, the book highlights key techniques and methodologies that have driven recent discoveries in bacterial pathogenesis, major structures and mechanisms in bacteria that are important for the pathogenesis of these organisms, the regulation of these virulence determinants by global regulators, and bacterial biowarfare agents. Molecular Paradigms of Infectious Disease: A Bacterial Perspective is an ideal book for students, microbiologists, immunologists and scientists and researchers of bacterial pathogenesis.
Molecular Mechanisms of Neurotransmitter Release
Within the complex neuronal network of the nervous system, neuron-to-neuron communication occurs mainly through chemical synapses, where the presynaptic nerve terminal releases neurotransmitters that control the function of postsynaptic neurons by acting on postsynaptic receptors. Recent decades have brought groundbreaking new developments and a wealth of knowledge to this field. In Molecular Mechanisms of Neurotransmitter Release, leading experts provide concise, up-to-date information on all major molecular mechanisms involved, with complete background information and figures and diagrams to further elucidate key concepts or experiments.Comprehensive and cutting-edge, Molecular Mechanisms of Neurotransmitter Release is sure to provide a learning tool for neuroscience students, a solid reference for neuroscientists, and a source of knowledge for all those who have a general interest in the ever-evolving field of neuroscience.
Molecular Mechanisms of Basal Cell and Squamous Cell Carcinomas
apid progress in the understanding of carcinogenesis and pathology of epitheUal skin cancer has led to new strategies for the prevention Rand treatment of these malignancies. The goal of this volume is to comprehensively cover in a highly readable overview our present knowledge of pathogenetic mechanisms and molecular biology of Basal Cell and Squamous Cell Carcinomas. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in epidemiology, histology, photobiology, immunology, cytogenetics, and molecular pathol ogy to new concepts for prophylaxis and treatment. Experts in the field as well as health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of this book to summarize essential up-to-date information for clinicians and scientists interested in the biology of Basal Cell and Squamous Cell Carcinomas. The chapters are written by authors who are experts in their respective research areas, and I am gratefixl for their willingness to contribute to this book.
Molecular bio-sensors and the role of metal ions
Represents a milestone of contemporary progress and understanding of molecular bio-sensors for metal ions. It is bringing together the latest research in academia and industry, and it also emphasizes the spectrum of evolving regulations from regulatory bodies. This vibrant research area is covered by 31 internationally recognized experts. The impact of MILS-23 is manifested by more than 1300 references and close to 200 figures, more than 100 of them in color; further information is summarized in several tables. In conclusion, Volume 23 significantly advances our understanding of Molecular Bio-Sensors, it is therefore an essential resource for scientists working in the wide range from earth sciences, material sciences, physics, pharmacology, enzymology, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic.
Molecular Biomethods Handbook
Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. Molecular Biomethods Handbook, 2nd Edition expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Part A of the book describes nucleic acid methods, such as gene expression profiling, microarray analysis and quantitative PCR. In Part B, protein and cell-based methods are outlined, in subjects ranging from protein engineering to high throughput screening. Written by a well-established panel of research scientists, Molecular Biomethods Handbook, 2nd Edition provides an up-to-date collection of methods used regularly in the authors’ own research programs.
Modulation of host gene expression and innate immunity by viruses
This book is reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases.
Modern Meteor Science : An Interdisciplinary View
"During the past half century meteor research has evolved into a comprehensive multidisciplinary science … . New findings are flowing from the ever-broadening range of investigative techniques that are being employed to great effect by the contributors to this book. This comprehensive overview of leading edge research by well over one hundred authors is an essential resource volume for scientists and engineers conducting studies and exploration of the solar system. It demands a place in the libraries supporting their activities.
