الصفحة 3
الصفحة 3
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Modern Trends in Geomechanics

This book is loaded with rich and stimulating articles by a roster of brilliant scholars, reflecting some recent trends in the frontier research of geomechanics. This collection of 32 contributions stems from an international workshop on "Modern Trends of Geomechanics" held in Vienna. The contributions span a wide range of topics and an enormous range of physical scales, from micromechanics at grain scale to engineering problems at large scale; from laboratory and field testing over constitutive modelling to numerical analysis.

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Modern Multivariate Statistical Techniques : Regression, Classification, and Manifold Learning

Remarkable advances in computation and data storage and the ready availability of huge data sets have been the keys to the growth of the new disciplines of data mining and machine learning, while the enormous success of the Human Genome Project has opened up the field of bioinformatics. These exciting developments, which led to the introduction of many innovative statistical tools for high-dimensional data analysis, are described here in detail. The author takes a broad perspective; for the first time in a book on multivariate analysis, nonlinear methods are discussed in detail as well as linear methods.

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Modern Hematology : Biology and Clinical Management

The first chapters of this book contain a self-contained introduction to path integrals in Euclidean quantum mechanics and statistical mechanics. The resulting high-dimensional integrals can be estimated with the help of Monte Carlo simulations based on Markov processes. The most commonly used algorithms are presented in detail so as to prepare the reader for the use of high-performance computers as an “experimental” tool for this burgeoning field of theoretical physics. Several chapters are then devoted to an introduction to simple lattice field theories and a variety of spin systems with discrete and continuous spins, where the ubiquitous Ising model serves as an ideal guide for introducing the fascinating area of phase transitions. As an alternative to the lattice formulation of quantum field theories, variants of the flexible renormalization group methods are discussed in detail. Since, according to our present-day knowledge, all fundamental interactions in nature are described by gauge theories, the remaining chapters of the book deal with gauge theories without and with matter.

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Models of the Atomic Nucleus

Models of the Atomic Nucleus is a largely non-technical introduction to nuclear theory – an attempt to explain the nucleus in a way that makes nuclear physics as comprehensible as chemistry or cell biology. Unlike many other scientific fields, the "popularization" of nuclear physics has not previously been successful because many fundamental issues remain controversial and a unified theory of nuclear structure has not yet been established. The theme developed in this book is that the many models of nuclear theory each provide a partial perspective on the nucleus and that the many models can in fact be integrated into a coherent whole and expressed in terms of a lattice of nucleons.

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Modeling of metal forming and machining processes : By finite element and soft computing methods

The physics of metal forming and metal removing is normally expressed using non-linear partial differential equations which can be solved using the finite element method (FEM). However, when the process parameters are uncertain and/or the physics of the process is not well understood, soft computing techniques can be used with FEM or alone to model the process.

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Modeling Chemical Systems using Cellular Automata

The book will be of great value in undergraduate courses in chemistry, physics, biology, applied mathematics, and bioinformatics, and as a supplement for laboratory courses in introductory chemistry, organic chemistry, physical chemistry, medicinal chemistry, chemical engineering and other courses dealing with statistical and dynamic systems. It allows the exploration of a wide range of dynamic phenomena, many of which are not normally accessible within conventional laboratory settings due to limitations of time, cost, and experimental equipment. The book is both a textbook on applied Cellular Automata and a lab manual for chemistry (physics, engineering) courses with lab activity. It would supplement other lab work and be an additonal book the students would use in the course.

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Model-based Process Supervision : A Bond Graph Approach

Model-based fault detection and isolation requires a mathematical model of the system behaviour. Modelling is important and can be difficult because of the complexity of the monitored system and its control architecture. The authors use bond-graph modelling, a unified multi-energy domain modelling method, to build dynamic models of process engineering systems by composing hierarchically arranged sub-models of various commonly encountered process engineering devices. The structural and causal properties of bond-graph models are exploited for supervisory systems design.

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Mitral valve diseases

The heart is a pump consisting of 4 chambers:2 atria and 2 ventricles and 4 valves one of them is mitral valve which is located betweenthe left atrium and the left ventricle and prevents the backward flow of blood.Ithas several unique features: Mitral annulus, two leaflets, the chordae tendineaeand papillary muscles. The mitral valve may become stenotic or may regurgitate. Regurgitation(or leakage of the valve): When the valve (s) do not close completely. Stenosis (or narrowing of the valve): When the valve (s) opening becomes narrowed. Mitral stenosis is categorized as mild, moderate or severe it is typically causedby (Rheumatic fever, A congenital heart, Calcium deposits .....) and it caused severalsymptoms such as: dyspnea, hemoptysis, fatigue, Chest pain and others Where as the Signs and symptoms of mitral valve regurgitation, can include: Abnormal heart sound, Shortness of breath, Heart palpitations, Fatigue, edma, Coughing.

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Mitochondria and the Heart

The function of the heart is highly dependent on oxidative energy that is generated in mitochondria. Defects in mitochondrial structure and function can be found in association with cardiovascular diseases. Mitochondria and the Heart discusses the role that mitochondria plays in cardiovascular disease, including biogenesis and function of cardiac mitochondria during normal growth, development and aging. In addition, nonbioenergetic, biogenesis and degradation pathways are explored. Understanding these pathways and the effects that mitochondrial defects have in cardiac pathology is extremely important in establishing the diagnosis and treatment of mitochondrial-based cardiac diseases.

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Minimally Invasive Tumor Therapies

In the age of the World Wide Web, informed patients continue to surprise oncologists with detailed questions about popular tumor therapies. Although minimally invasive tumor therapies (MITT) have become daily clinical practice for palliative treatment of liver tumors, the acceptance of these palliative modalities still varies enormously. In addition, promising results have been published for in situ ablation of lung metastases, bone tumors, and renal cell carcinoma. This book gives an up-to-date overview of the popular techniques and clinical results of MITT, with a clarification of the actual indications including the size, tumor entities, and clinical benefits. Moreover, the book focuses on the prospectives and limitations of imaging methods - ultrasound, computed tomography, and magnetic resonance imaging - used for MITT.

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Minimally Invasive Neurosurgery and Neurotraumatology

Neurotraumatology patients present an enormous challenge to society. Neuros- gical management of brain and spinal cord injury has been a frustrating area, as s- gical methods, especially in moderate and severe injuries, have been limited to control of brain and spinal compression, control of intracranial pressure with its expected effect on cerebral blood flow, and structural repair of the supporting structures (skull, spine, brain and spinal cord coverings). Achieving the best outcome for the neu- traumatology patient, however, requires much more than that.

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Migrants and Expats : The Swiss Migration and Mobility Nexus

This book provides insight on current patterns of migration in Switzerland, which fall along a continuum from long-term and permanent to more temporary and fluid. These patterns are shaped by the interplay of legal norms, economic drivers and societal factors. The various dimensions of this Migration-Mobility Nexus are investigated by means of newly collected survey data: the Migration-Mobility Survey. The book covers different aspects of life in the host country, including the family dimension, the labour market and political participation as well as social integration. The book also takes into account the chronological dimension of migration by considering the migrants’ arrival, their stay, and their expectations regarding return.

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Micro-, Meso- and Macro-Connectomics of the Brain

Highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

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Metamorphoses of Hamiltonian Systems with Symmetries

Modern notions and important tools of classical mechanics are used in the study of concrete examples that model physically significant molecular and atomic systems. The parametric nature of these examples leads naturally to the study of the major qualitative changes of such systems (metamorphoses) as the parameters are varied. The symmetries of these systems, discrete or continuous, exact or approximate, are used to simplify the problem through a number of mathematical tools and techniques like normalization and reduction. The book moves gradually from finding relative equilibria using symmetry, to the Hamiltonian Hopf bifurcation and its relation to monodromy and, finally, to generalizations of monodromy.

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Metabolism and Functions of Bioactive Ether Lipids in the Brain

This book will be particularly useful to neuroscience graduate students, academics, and researchers. Clinicians will find this book useful for understanding molecular aspects of neurodegeneration in acute neural trauma and neurodegenerative diseases that are mediated by plamalogen-selective phospholipases A2 and PAF acetyl hydrolases. This monograph is the first to provide a comprehensive description of not only metabolism and role of plasmalogen and platelet activating factor in brain tissue but also the involvement of these lipids with abnormal signal transduction processes in neurological disorders.

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Meshfree Methods for Partial Differential Equations II

A Particle Strategy for Solving the Fokker-Planck Equation Modelling the Fiber Orientation Distribution in Steady Recirculating Flows Involving Short Fiber Suspensions.- Extended Meshfree Method for Elastic and Inelastic Media.- Meshfree Petrov-Galerkin Methods for the Incompressible Navier-Stokes Equations.- The ?-shape Based Natural Element Method in Solid and Fluid Mechanics.- A Particle-Partition of Unity Method Part VI: A p-robust Multilevel Solver.- Enriched Reproducing Kernel Approximation: Reproducing Functions with Discontinuous Derivatives.- Reproducing Kernel Element Interpolation: Globally Conforming I m/C n/P k Hierarchies.- Multi-scale Analysis Using Two Influence Radii in EFGM.- Solution of a Dynamic Main Crack Interaction with a System of Micro-Cracks by the Element Free Galerkin Method.- Finite Cover Method for Physically and Geometrically Nonlinear Problems.- A Numerical Scheme for Solving Incompressible and Low Mach Number Flows by the Finite Pointset Method.- SPH Renormalized Hybrid Methods for Conservation Laws: Applications to Free Surface Flows.- Discontinuous Radial Basis Function Approximations for Meshfree Methods.- Treating Moving Interfaces in Thermal Models with the C-NEM.- Bridging Scale Particle and Finite Element Methods.

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Medical Image Computing and Computer-Assisted Intervention – MICCAI 2005 ; 8th International Conference, Palm Springs, CA, USA, October 26-29, 2005, Proceedings, Part I

This paper presents a method for classification of medical images, using machine learning and deformation-based morphometry. A morphological representation of the anatomy of interest is first obtained using highdimensional template warping, from which regions that display strong correlations between morphological measurements and the classification (clinical) variable are extracted using a watershed segmentation, taking into account the regional smoothness of the correlation map which is estimated by a crossvalidation strategy in order to achieve robustness to outliers. A Support Vector Machine-Recursive Feature Elimination (SVM-RFE) technique is then used to rank computed features from the extracted regions, according to their effect on the leave-one-out error bound. Finally, SVM classification is applied using the best set of features, and it is tested using leave-one-out. The results from a group of 61 brain images of female normal controls and schizophrenia patients demonstrate not only high classification accuracy (91.8%) and steep ROC curves, but also exceptional stability with respect to the number of selected features and the SVM kernel size

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Mechanisms of Insulin Action

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.

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Mechanics of Materials

Provides a review of statics, covering the topics needed to begin the study of mechanics of materials including free-body diagrams, equilibrium, trusses, frames, centroids, and distributed loads. It presents the foundations and applications of mechanics of materials with emphasis on visual analysis, using sequences of figures to explain concepts and giving detailed explanations of the proper use of free-body diagrams. The Cauchy tetrahedron argument is included, which allows determination of the normal and shear stresses on an arbitrary plane for a general state of stress. An optional chapter discusses failure and modern fracture theory, including stress intensity factors and crack growth.

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Mechanical Engineering : Grundlagen des Maschinenbaus in englischer Sprache

Dieses Lehrbuch in englischer Sprache bietet für deutschsprachige Studierende einen Einstieg in die englischen Fachbegriffe der Ingenieurwissenschaften. Es enthält Grundkenntnisse einzelner Bereiche des Maschinenbaues wie Mechanik, Maschinenelemente, Thermodynamik oder auch Fertigungstechnik.

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