الصفحة 3
الصفحة 3
Notch Signaling in Embryology and Cancer : Notch Signaling in Cancer
This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.
Nonparametric Monte Carlo Tests and Their Applications
A fundamental issue in statistical analysis is testing the fit of a particular probability model to a set of observed data. Monte Carlo approximation to the null distribution of the test provides a convenient and powerful means of testing model fit. Nonparametric Monte Carlo Tests and Their Applications proposes a new Monte Carlo-based methodology to construct this type of approximation Every chapter of the book includes algorithms, simulations, and theoretical deductions. The prerequisites for a full appreciation of the book are a modest knowledge of mathematical statistics and limit theorems in probability,empirical process theory.
Nonlinear Finite Element Methods
Finite element methods have become ever more important to engineers as tools for design and optimization, now even for solving non-linear technological problems. However, several aspects must be considered for finite-element simulations which are specific for non-linear problems: These problems require the knowledge and the understanding of theoretical foundations and their finite-element discretization as well as algorithms for solving the non-linear equations. This book provides the reader with the required knowledge covering the complete field of finite element analyses in solid mechanics.
Nonlinear dynamics of a wheeled vehicle
This book provides an overview of the theory of stability analysis and its applications. It is focused on various methods devoted to analyzing wheeled vehicle behavior. The authors provide both basic and advanced knowledge of the subject.
Nonlinear dynamics in complex systems via fractals and fractional calculus
Current advances in the knowledge of nonlinear dynamical networks, systems and processes, as well as their unified repercussions, allow us to include some typical complex natural phenomena, from the nanoscale to an extra-galactic scale, in an unitarian comprehensive manner. In other words, the physical, biological and financial data, as well as technological ones (mechanical or electronic devices), of complex systems available today can be managed by the same unique conceptual approach, both analytically and through a computer simulation, using effective nonlinear dynamics procedures. This volume collected some important advances in the fields of fractal curves, fractal analysis and fractional calculus, as well as new solutions of fractal differential equations.
Noncommunicable diseases
Focuses on cardiovascular disease, diabetes, cancer and chronic respiratory disease and their five shared main risk factors (tobacco use, harmful use of alcohol, unhealthy diet, physical inactivity and air pollution) as defined by the United Nations, this book provides a synopsis of one of the world’s biggest challenges of the 21st century. NCDs prematurely claim the lives of millions of people across the world every year, with untold suffering to hundreds of millions more, trapping many people in poverty and curtailing economic growth and sustainable development. While resources between and within countries largely differ, the key principles of surveillance, prevention and management apply to all countries, as does the need to focus resources on the most cost-effective and affordable interventions and the need for strong political will, sufficient resources, and sustained and broad partnerships. This compendium consists of 59 short and accessible chapters in six sections: (i) describing and measuring the burden and impact of NCDs / (ii) the burden, epidemiology and priority interventions for individual NCDs / (iii) social determinants and risk factors for NCDs and priority interventions / (iv) global policy / (v) cross-cutting issues / and (vi) stakeholder action.
NF-kB/Rel Transcription Factor Family
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
Nexus Network Journal : Leonardo da Vinci : Architecture and Mathematics
The quintessential Renaissance Man, Leonardo da Vinci was well aware of the fundamental importance of mathematics for architecture. This issue of the Nexus Network Journal examines Leonardo’s knowledge of theoretical mathematics, explores how he used concepts of geometry in his designs for architectural projects, and reports on a real-life construction project using Leonardo’s principles. Authors include Sylvie Duvernoy, Kim Williams, Rinus Roelofs, Biagio Di Carlo, Mark Reynolds, João Pedro Xavier, Vesna Petresin, Christopher Glass, and Jane Burry. To complete the issue Rachel Fletcher writes her Geometer’s Angle column on "Dynamic Symmetry", Michael Ostwald reviews A Theory of General Ethics by Warwick Fox, Sarah Clough Edwards reviews Inigo Jones and the Classical Tradition by Christy Anderson, and Sylvie Duvernoy reviews Architecture and Mathematics in Ancient Egypt by Corinna Rossi.
Next generation probiotics from novel drugs to future therapeutics
Provides a comprehensive and cutting-edge exploration of probiotics as powerful therapeutic agents. With the rapid advancements in the field, this book offers a deep dive into how probiotics are evolving beyond traditional uses, addressing complex health conditions and diseases in modern medicine. By combining the latest scientific research with practical applications, this book equips researchers, clinicians, and healthcare professionals with the knowledge needed to incorporate probiotics into clinical practice and future therapeutic strategies.
Next generation information technologies and systems ; 6th International Conference, NGITS 2006, Kebbutz Sehfayim, Israel, July 4-6, 2006, Proceedings
The selected papers may be classified roughly in ten broad areas: ? Information systems development ? Distributed systems ? Semi-structured data ? Data mining and agent-oriented computing ? User-oriented design ? Frameworks, models and taxonomies ? Simulation and incremental computing ? Information integration ? Security and privacy ? Next-generation applications This event is the culmination of efforts by many talented and dedicated individuals.
Newman and Carranza's essentials of clinical periodontology : An integrated study companion
An Integrated Study Companion provides core information on periodontology and implant dentistry in a format that reflects the current, case-based U.S. National Board Dental Examination. Each chapter ends with a case-based exercise, allowing you to apply your knowledge to the practice setting. Like the well-known Newman and Carranza’s Clinical Periodontology textbook, it covers everything from basic science and fundamental procedures to advanced techniques in reconstructive, esthetic, and implant therapy — but with a focus on need-to-know content.
Newman and Carranza's Clinical Periodontology and Implantology
Provides detailed, up-to-date information on the etiology and pathogenesis of periodontal disease. Basic and advanced evidence-based information on the various treatment modalities employed in periodontics and implantology is presented in an easy-to-read format, with callout boxes throughout the text highlighting the clinical relevance of foundational basic science information. Full-color photos and radiographic images depict periodontal conditions and procedures, and the Atlas of Periodontal Pathology is one of the most comprehensive ever compiled in a periodontal textbook. Written by a team of leading experts led by Michael G. Newman, this text not only demonstrates how to perform periodontal procedures but explains the evidence supporting each treatment and provides knowledge on how to achieve the best possible outcomes of periodontal therapy and implant treatment. An eBook version is included with print purchase, providing access to all the text, figures, and references, plus the ability to search, customize content, make notes and highlights, and have content read aloud.
Newman and Carranza’s Clinical Periodontology
An Integrated Study Companion provides core information on periodontology and implant dentistry in a format that reflects the current, case-based U.S. National Board Dental Examination. Each chapter ends with a case-based exercise, allowing you to apply your knowledge to the practice setting. Like the well-knownNewman and Carranza's Clinical Periodontology textbook, it covers everything from basic science and fundamental procedures to advanced techniques in reconstructive, esthetic, and implant therapy - but with a focus on need-to-know content.
New Trends in Databases and Information Systems ; ADBIS 2020 Short Papers, Lyon, France, August 25–27, 2020, Proceedings
This book constitutes thoroughly refereed short papers of the 24th European Conference on Advances in Databases and Information Systems, ADBIS 2020, held in August 2020. ADBIS 2020 was to be held in Lyon, France, however due to COVID-19 pandemic the conference was held in online format. The 18 presented short research papers were carefully reviewed and selected from 69 submissions. The papers are organized in the following sections: data access and database performance; machine learning; data processing; semantic web; data analytics.
New Trends in Cancer for the 21st Century
It is difficult to imagine anyone who has not heard of cancer. This disease can affect families, friends or any one of us at any time in our lives. Every year nearly 3 million Europeans are diagnosed with cancer, leading to around 800,000 deaths per year. These deaths occur not only in aging populations, but also in children and adults who are in the most active period of their lives. This represents a tremendous problem that cannot be ignored by politicians or citizens. Fortunately, there is a constantly growing awareness that although cancer is a problem to be dealt with by clinicians, it should also be the concern of everyone. This volume contains the lectures held at the International Symposium on Cancer "New Trends in Cancer for the 21st Century". Fundamental researchers, politicians and representatives from patient coalitions share here their knowledge and interests as well as their concerns and experiences. Not only do these papers provide state-of-the-art information on cancer, they are also an opportunity to look at the problem from different points of view. It can be encouraging to realise that we are not alone in this fight.
New Technologies, Mobility and Security
NTMS’2007 is the first IFIP International Conference on New Technologies, Mobility and Security that was held from May 2 to May 4, 2007 in Paris, France. NTMS'2007 aims at fostering advances in the areas of New Technologies, Wireless Networks, Mobile Computing, Ad hoc and Ambient Networks, QoS, Network Security and E-commerce, to mention a few, and provides a dynamic forum for researchers, students and professionals to present their state-of-the-art research and development in these interesting areas. The event was combined with tutorial sessions and workshops. Tutorials preceded the main program, aiming at the dissemination of mature knowledge and technology advances in the field. One Workshop immediately followed the main conference, offering the opportunity for a more focused exchange of ideas and presentation of on-going research relevant to selected topics.
New product development : An empirical approach to study of the effects of innovation strategy, organization learning and market Conditions
New product development (NPD) is considered as a process of learning. Successful NPD projects typically rely on knowledge and experience of multi-function teams. In addition to corporate strategy and organization learning, the external factors such as, market and competitive conditions also play a big role in driving business strategies.
New Perspectives in the Study of Mesoamerican Primates : Distribution, Ecology, Behavior, and Conservation
The purpose of this volume is to present a comprehensive overview of recent advances in primate field research, ecology, and conservation biology in Mesoamerica. The overall goal of each contribution is to integrate newly collected field data with theoretical perspectives drawn from evolutionary biology, socioecology, biological anthropology, and conservation to identify how our current knowledge of primate behavior and ecology has moved beyond more traditional approaches. A corollary to this, and an important goal of the volume is to identify geographical regions and species for which we continue to lack sufficient information, to develop action plans for future research, and to identify areas for immediate conservation action. Despite many decades of primate research in Mesoamerica, much is still unknown concerning the basic ecology and behavior of these species, demography, current distribution, and conservation status of local populations, and the effectiveness of conservation policies on primate survivorship. Four major areas of research are the focus of the volume: Evolutionary Biology and Biogeography; Population Demography and Ecology; Behavior; and Conservation and Management Policies.
New metropolitan perspectives : Knowledge dynamics, innovation-driven policies towards the territories’ attractiveness ; Vol.1
This book presents the outcomes of the symposium “NEW METROPOLITAN PERSPECTIVES,” held at Mediterranea University, Reggio Calabria, Italy on May 26–28, 2020.
New Light on Dark Stars : Red Dwarfs, Low-Mass Stars, Brown Stars
There has been very considerable progress in research into low-mass stars, brown dwarfs and extrasolar planets during the past few years, particularly since the fist edtion of this book was published in 2000. In this new edtion the authors present a comprehensive review of both the astrophysical nature of individual red dwarf and brown dwarf stars and their collective statistical properties as an important Galactic stellar population. Chapters dealing with the observational properies of low-mass dwarfs, the stellar mass function and extrasolar planets have been completely revised. Other chapters have been significantly revised and updated as appropriate, including important new material on observational techniques, stellar acivity, the Galactic halo and field star surveys. The authors detail the many discoveries of new brown dwarfs and extrasolar planets made since publication of the first edition of the book and provide a state-of-the-art review of our current knowledge of very low-mass stars, brown dwarfs and extrasolar planets, including both the latest observational results and theoretical work.
