الصفحة 3
الصفحة 3
Modeling Decisions for Artificial Intelligence ; 4th International Conference, MDAI 2007, Kitakyushu, Japan, August 16-18, 2007, Proceedings
Decision modeling is a key area in the developing field of AI, and this timely work connects researchers and professionals with the very latest research. It constitutes the refereed proceedings of the 4th International Conference on Modeling Decisions for Artificial Intelligence, held in Kitakyushu, Japan, in August 2007.
Model-Based Software and Data Integration ; 1st International Workshop, MBSDI 2008, Berlin, Germany, April 1-3, 2008. Proceedings
The First International Workshop on Model-Based Software and Data Integ- tion (MBSDI 2008), was ourfrst event of this kind in a forthcoming series of activities at TU Berlin, where a scientifc discussion and exchange forum was provided for both academic and industrial researchers. We aimed at researchers, engineersand practitionerswho focus onadvanced, model-basedsolutions inthe area of software and information integration and interoperability. As withevery beginning, the resonanceonour callsin today's overfoodingof workshops was somewhat unpredictable, and we did not really know how many paper submissions to expect. We were nicely surprised, considering the rather short lead time to organize the meeting and the very specialized and focused topic.
Mobility, data mining and privacy : Geographic knowledge discovery
This book assesses this research frontier from a computer science perspective, investigating the various scientific and technological issues, open problems, and roadmap. The editors manage a research project called GeoPKDD, Geographic Privacy-Aware Knowledge Discovery and Delivery, funded by the EU Commission and involving 40 researchers from 7 countries, and this book tightly integrates and relates their findings in 13 chapters covering all related subjects, including the concepts of movement data and knowledge discovery from movement data; privacy-aware geographic knowledge discovery; wireless network and next-generation mobile technologies; trajectory data models, systems and warehouses; privacy and security aspects of technologies and related regulations; querying, mining and reasoning on spatiotemporal data; and visual analytics methods for movement data.
Mining Complex Data ; ECML/PKDD 2007 Third International Workshop, MCD 2007, Warsaw, Poland, September 17-21, 2007, Revised Selected Papers
This book constitutes the refereed proceedings of the Third International Workshop on Mining Complex Data, MCD 2007, held in Warsaw, Poland, in September 2007, co-located with ECML and PKDD 2007.The 20 revised full papers presented were carefully reviewed and selected; they present original results on knowledge discovery from complex data. In contrast to the typical tabular data, complex data can consist of heterogenous data types, can come from different sources, or live in high dimensional spaces. All these specificities call for new data mining strategies.
Microwave-Assisted Synthesis of Heterocycles
This book is Volume I of a new series by Springer entitled Topics in Heterocyclic Chemistry. At present, there are six such monographs in this series, the overall scope of which is to cover "current trends in heterocyclic chemistry". Given the importance of heterocylic natural products and heterocyclic scaffolds in the realm of medicinal chemistry and drug discovery, an up-todate series on this subject is well warranted, and a survey of the recent impact of microwave-assisted synthesis on this venerable field is both timely and needed
Microwave Methods in Organic Synthesis
We are delighted to present this volume with contributions from some of themost renowned and experienced microwave chemists today.The delivery and introduction of energy has been closely connected withthe discovery and investigation of new chemistry. It is with pleasure thatwe have seen an increased use of microwave irradiation over the years andwe hope that this volume will reflect the current interest in expanding thescope of microwave applications in both organic and medicinal chemistry. Oneimportant explanation behind the growth of microwave-enhanced chemistryhas been the introduction of dedicated microwave reactors.As a result of this development we are proud to present a diverse set of re-views.
Microbiomes and emerging applications
Covers a range of important topics and recent advances in metagenomics, microbiomes and their emerging applications, including microbiota transplantation and its health implications. It also discusses microbiome composition and development in humans. The contributors of this volume provide detailed information on prebiotics and probiotics for enhanced human health. They also introduce microbiomes as the next frontiers in medicine, agriculture, industry and environment. A chapter is presented that discusses probiotic research studies in Nigeria and Canada that led to the discovery of Lactobacillus pentosus KCA1. The book contains timely knowledge and will be useful reference material for scientists and researchers working in the fields of food and agricultural biotechnology, biopharmaceuticals and medical biotechnology, fermentation technology, environmental biotechnology, microbiomes and microbial biotechnology and health care.
MICAI 2006 : Advances in Artificial Intelligence ; 5th Mexican International Conference on Artificial Intelligence, Apizaco, Mexico, November 13-17, 2006, Proceedings
This volume contains the papers presented during the oral session of the 5 Mexican International Conference on Artificial Intelligence, held on November 13–17, 2006, at the Technologic Institute of Apizaco, Mexico. The conference received for evaluation 448 submissions by 1207 authors from 42 different countries
Metalearning : Applications to Automated Machine Learning and Data Mining
This book as one of the fastest-growing areas of research in machine learning, metalearning studies principled methods to obtain efficient models and solutions by adapting machine learning and data mining processes. This adaptation usually exploits information from past experience on other tasks and the adaptive processes can involve machine learning approaches. As a related area to metalearning and a hot topic currently, automated machine learning (AutoML) is concerned with automating the machine learning processes. Metalearning and AutoML can help AI learn to control the application of different learning methods and acquire new solutions faster without unnecessary interventions from the user.
Metal-containing molecules and nanomaterials : from diagnosis to therapy
Since the discovery and successful deployment of salvarsan to treat syphilis, as well as cisplatin as a cancer drug, the field of metallodrugs has been flourishing. In addition to therapeutic applications, metals and metal-containing molecules have properties, such as an electrochemical or an optical signal, used to diagnose biologically relevant molecules or unravel cellular metabolism. Metals are part of the essential elements for life, and of increased attention in nutraceuticals. Most of the current diagnosis processes, therapeutics and nutraceuticals are based on organic molecules. MILS-26 reviews the most recent metal-containing molecules and nanomaterials for diagnosis and therapy
Metabolome Analyses : Strategies for Systems Biology
Metabolome Analyses is intended as a follow-up to Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (Kluwer, 2003). That text offered guidelines to currently available technology, bioinformatics and databases. Evidence was presented showing metabolic profiling as a valuable addition to genomics and proteomics strategies devoted to drug discovery and development. This book focuses on how metabolic profiling is being more comprehensively integrated with the other "omics" technologies. It provides more practical applications of such "panomics" or "Systems Biology" approaches. The expanding use of mass spectrometry as a measurement technology in metabolic profiling is addressed through demonstrated applications. The integration of metabolic profiling and proteomics is probably most developed for plant-based studies, which was not addressed in Volume 1. Other areas related to metabolic profiling continue to show significant development. These include database strategies and an increased acceptance by the pharmaceutical industry of metabolic profiling. Also covered is the use of in silico metabolic networks. Again the focus is primarily on the pharmaceutical industry but the importance of metabolic profiling to studies on human nutrition (a burgeoning area) is discussed.
Melting Hadrons, Boiling Quarks - From Hagedorn Temperature to Ultra-Relativistic Heavy-Ion Collisions at CERN : With a Tribute to Rolf Hagedorn
Shows how the study of multi-hadron production phenomena in the years after the founding of CERN culminated in Hagedorn's pioneering idea of limiting temperature, leading on to the discovery of the quark-gluon plasma -- announced, in February 2000 at CERN.
Medicinal foods as potential therapies for type-2 diabetes and associated diseases : The chemical and pharmacological basis of their action
Focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. Provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries.
Medicinal Chemistry for Practitioners
Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes features important insights into the applications of fullerenes and carbon nanotubes. It discusses the fullerene and nanotubes derivatives which are effective against viruses, cells, and bacteria and those which are able to interact and inhibit certain enzymes. Also covered in this book are the formation of complex structures between biologically active molecules and carbon materials. Furthermore, the application of fullerenes in certain medical therapies is explored, including the very recent discovery of new bio-compatible media which could be used as carriers in the delivery of fullerenes in vivo. An additional topic of this text is the formation of hybrids between nanotubes and biological molecules and their use as chemical sensors.
Medical Reprints: 3D ed.
3D printing or additive manufacturing is a novel method of manufacturing parts directly from a digital model by using layer by layer material build-up approaches. This discovery is predicted to have the greatest impact on the future industries. Additive manufacturing has numerous applications in different areas including healthcare. Applications encompass many medical fields such as dentistry, surgery, and medical devices as well as the pharmaceutical field. Due to transplant donor deficiencies, ‘bioprinting’ has been invented to print biocompatible organs. Adding ‘time’ as a 4th dimension, 4D printing uses ‘smart materials’ to initiate the ‘smart drugs’ era.
Mathematical Tools for Data Mining : Set Theory, Partial Orders, Combinatorics
Mathematics is presented in a thorough and rigorous manner offering a detailed explanation of each topic, with applications to data mining such as frequent item sets, clustering, decision trees also being discussed. More than 400 exercises are included and they form an integral part of the material. Some of the exercises are in reality supplemental material and their solutions are included. The reader is assumed to have a knowledge of elementary analysis.
Ion channels as targets in drug discovery
Built around ion channel research and, more specifically, ion channels as important therapeutic drug targets. Under the editorial leadership of Gary Stephens in academic research and Edward Stevens from industry, the aim is to bring these strands together to provide a cutting-edge translational reference on ion channel drug discovery. Exploiting our knowledge of ion channel structure and function has clear current and future potential to intervene and correct the pathophysiology associated with debilitating conditions, including cardiovascular disease, diabetes, cystic fibrosis, pain, epilepsy, and neurodegenerative disorders. Individual chapters have a disease focus, also providing a “case study story” that will also appeal to a clinical audience
Introduction to Optics
Since the discovery of the laser in 1960 and optical fibers in 1970, optics has undergone dramatic changes that accentuate its multi-disciplinary character. This text covers essential concepts and reports the key developments and progress in current knowledge in the field. Inspired by the style of Richard Feynman, the method of presentation emphasizes "telling" optics, rather than deducing it from fundamental laws, as well as tactfully using mathematical tools so as not to obscure the physical phenomena of interest. For its excellent teaching approach, the book received the Arnulf-Francon Award of the French Optical Society. The concepts are formulated in a way such that the necessary mathematical tools do not hinder comprehension of the phenomena. Global in vision, the book can also be used as a reference. In addition to the traditional aspects of optics, it includes the tools and methods currently used by researchers and engineers, as well as explanation and implications of the most recent developments.
Introduction to Data Mining and its Applications
This book explores the concepts of data mining and data warehousing, a promising and flourishing frontier in data base systems and new data base applications and is also designed to give a broad, yet in-depth overview of the field of data mining. Data mining is a multidisciplinary field, drawing work from areas including database technology, AI, machine learning, NN, statistics, pattern recognition, knowledge based systems, knowledge acquisition, information retrieval, high performance computing and data visualization.
