الصفحة 3
الصفحة 3
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Pro Nagios 2.0

Pro Nagios 2.0 explains how to install and administer Nagios, the web-based enterprise management tool that helps monitor Unix, Windows, network devices, infrastructure equipment, and applications. You'll learn how to architect Nagios installations, deploy agents and plug-ins, and monitor a variety of assets, which include applications across a variety of platforms and operating systems. Nagios has the power to alert you to current and future incidents that could impact the availability, performance, and security of monitored assets.

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Principles, Systems and Applications of IP Telecommunications. Services and Security for Next Generation Networks ; 2nd International Conference, IPTComm 2008, Heidelberg, Germany, July 1-2, 2008. Revised Selected Papers

This book constitutes the thoroughly refereed proceedings of the 10th International Workshop on Principles, Systems and Applications of IP Telecommunications, held in Heidelberg, Germany, in July 2008.The 16 full papers presented were carefully reviewed and selected from a total of 56 submissions. Topics covered include recent advances in the domains of convergent networks, VoIP security, and multimedia service environments for next generation networks.

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Principles of structural design : Wood, steel, and concrete

Timber, steel, and concrete are common engineering materials used in structural design. Material choice depends upon the type of structure, availability of material, and the preference of the designer. The design practices the code requirements of each material are very different. In this updated edition, the elemental designs of individual components of each material are presented, together with theory of structures essential for the design.

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Principles of Electronic Prescribing

Electronic prescribing (EP) is a complex discipline, the success of which relies on the successful interplay of system design, data support and clinical practice. It represents the use of electronic systems to facilitate and enhance communication of a prescription or medicine order, and improves legibility and completeness of prescriptions, improves availability of electronic decision support tools at the point of prescribing, enables a comprehensive audit trail, and reduces medication-related errors. These benefits are far-reaching in significance, both in terms of their effects on risk management and risk reduction and their financial impact. Given the likely growth of interest in electronic medicines management, this discussion of relevant design issues and their impact is timely.

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Principles of Distributed Systems ; 12th International Conference, OPODIS 2008, Luxor, Egypt, December 15-18, 2008. Proceedings

The 30 full papers and 11 short papers presented were carefully reviewed and selected from 102 submissions. The conference focused on the following topics: communication and synchronization protocols; distributed algorithms and multiprocessor algorithms; distributed cooperative computing; embedded systems; fault-tolerance, reliability and availability; grid and cluster computing; location- and context-aware systems; mobile agents and autonomous robots; mobile computing and networks; peer-to-peer systems and overlay networks; complexity and lower bounds; performance analysis of distributed systems; real-time systems; security issues in distributed computing and systems; sensor networks; specification and verification of distributed systems; and testing and experimentation with distributed systems.

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Primate biogeography : Progress and prospects

Biogeography, the study of the distribution of organisms over the surface of the earth, plays a central role in our understanding of virtually all aspects of the biology of primates and other animals, including systematics, mechanisms of speciation, population genetics and demography. The distribution of primates relative to aspects of climate and habitat, including altitude, forest type, and food availability, forms the basis for our understanding of ecological and behavioral adaptations. The biogeography of primates in the past is a major component of our understanding of their evolutionary history and is an essential component of conservation biology. This volume, which brings together these papers on the biogeography of primates, past and present, provides an introduction to Primate Biogeography as a discipline, illustrates the many factors that may influence the distribution of primates, and demonstrates the wide range of methodological approaches that are available to understanding the distribution of this order.

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Preserving Privacy in On-Line Analytical Processing (OLAP)

Preserving Privacy in On-Line Analytical Processing reviews a series of methods that can precisely answer data cube-style OLAP queries regarding sensitive data while provably preventing adversaries from inferring the data. How to keep the performance overhead of these security methods at a reasonable level is also addressed. Achieving a balance between security, availability, and performance is shown to be feasible in OLAP systems.

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Practice of Intramedullary Locked Nails : New Developments in Techniques and Applications

The third volume of the "Practice of Intramedullary Locked Nails" places a special focus on recent advancements in understanding the biology of fracture healing of long bones, the emerging technologies that further enhance the minimally invasive nature of closed treatment of fractures, and the availability of various surgical techniques in intramedullary fixation. The application of new technology in prevention of infection and application of the intramedullary fixation of fractures in pediatric and adolescent patients are also described. The contributors to this volume are from different well-known trauma centers and are pioneer surgeons in the development and practice of intramedullary locked nails.

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Plant Litter : Decomposition, Humus Formation, Carbon Sequestration

This fully revised and updated 2nd edition of Plant Litter focuses on decomposition processes in natural terrestrial systems such as boreal and temperate forests. The availability of several long-term studies from these forest types allows a more in-depth approach to the later stages of decomposition as well as to humus formation. It further briefly explores how processes are modified due to anthropogenic influences. Earlier findings are re-evaluated in light of recent research and with relevance to current areas of investigation. New concepts that modify or go beyond those already presented are covered and a new chapter on patterns of decomposition and accumulation on a regional scale was introduced.

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PharmaFind Application Online Chat with Pharmacy

The origin of the idea for the Pharma Find application is the almost daily need to order and search for medicines in these conditions our country is going through, which is represented by the difficulties of finding some imported medications and the price dissimilarity from one pharmacy to another. There’s also the difficulty of searching for a required medication in the late hours of the night due to the lack of information about the locations of the available pharmacies and the availability of the medication in them.

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Pharmacokinetics and toxicokinetic considerations - Vol II ; 1st ed.

Explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists.

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Pharmacokinetics and pharmacodynamics of nanoparticulate drug delivery systems

Discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles.

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Pharmacokinetics : Basics to Applications

Covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature.

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Pharmaceutical dissolution testing, bioavailability, and bioequivalence : Science, applications, and beyond

Delivers a comprehensive and up-to-date reference covering the established and emerging roles of dissolution testing in pharmaceutical drug development. After discussing the fundamentals of the subject, the included resources go on to explore common testing practices and methods, along with their associated challenges and issues, in the drug development life cycle. A thorough introduction to the fundamentals and essential applications of pharmaceutical dissolution testing. Comprehensive explorations of the foundations and drug development applications of bioavailability and bioequivalence. Practical discussions about solubility, dissolution, permeability, and classification systems in drug development. In-depth examinations of the mechanics of dissolution, including mathematical models and simulations. An elaborate assessment of biophysiologically relevant dissolution testing and IVIVCs, and their unique applications. A complete understanding of the methods, requirements, and global regulatory expectations pertaining to dissolution testing of generic drug products

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Pharmaceutical cocrystals : Along the path to improved medicines

Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to differences in the intermolecular interactions, Differences in solid forms often lead to differences in thermodynamic parameters and physicochemical properties for example solubility {especially that a lot of drugs are in Class II and IV according to BCS (Biopharmaceutics Classification System) and these classes suffer from poor aqueous solubility and hence low bioavailability} ,dissolution rate, stability and mechanical properties of APIs and excipients. Hence, solid forms of APIs play a vital role in drug discovery and development.

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Payara Micro Revealed : Cloud-Native Application Development with Java

Shows how to develop microservices using RESTful web services, followed by how to create microservice clients using MicroProfile and the REST client API. Dependency Injection via Jakarta Context and Dependency Injection (CDI) is also covered. Various approaches to application configuration are covered as well, including property files, environment variables, and system properties. You will learn to configure fault tolerance and high availability, generate system and custom application metrics, and generate health checks to automatically improve overall application health. You will know how to trace the flow of a request across service boundaries with OpenTracing. You will learn : Develop microservices using standard Java APIs / Implement cloud functionality such as request tracing and health checks / Deploy applications as thin archives and as uber archives / Configure applications via Maven and Gradle / Generate custom metrics for capacity planning and proactive discovery of issues / Implement features in support of high availability and fault tolerance / Secure your applications with Jason Web Tokens / Take advantage of Payara’s own cloud platform for easy deployment

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Parameter Estimation in Stochastic Differential Equations

Parameter estimation in stochastic differential equations and stochastic partial differential equations is the science, art and technology of modelling complex phenomena and making beautiful decisions. The subject has attracted researchers from several areas of mathematics and other related fields like economics and finance. This volume presents the estimation of the unknown parameters in the corresponding continuous models based on continuous and discrete observations and examines extensively maximum likelihood, minimum contrast and Bayesian methods. Useful because of the current availability of high frequency data is the study of refined asymptotic properties of several estimators when the observation time length is large and the observation time interval is small. Also space time white noise driven models, useful for spatial data, and more sophisticated non-Markovian and non-semimartingale models like fractional diffusions that model the long memory phenomena are examined in this volume.

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Parallel programming : Technigues and applications using networked workstations and parallel computers

Covers the techniques of parallel programming in a practical manner that enables students to write and evaluate their parallel programs. Supported by the National Science Foundation and exhaustively class-tested, it is the first text of its kind that does not require access to a special multiprocessor system, concentrating instead only on parallel programs that can be executed on networked workstations using freely available parallel software tools. The Second Edition has been revised to incorporate a greater focus on cluster programming as this type of programming has become more widespread with the availability of low-cost computers.

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Palladium Emissions in the Environment : Analytical Methods, Environmental Assessment and Health Effects

To date the investigations of metal emissions from automotive catalysts has focussed mainly on platinum. Since 1993, however, platinum has been increasingly replaced by palladium as the predominant substance in pollution-control catalysts. Now the release of palladium in automotive catalysts is becoming just a critical problem as that of platinum. The editors present the latest research results related to all aspects of palladium emissions in the environment, as well as an assessement of their effects on the environment and health. The book focuses on the following topics: analytical methods; sources of palladium emissions; occurrence, chemical behaviour and fate in the environment; bioavailability and biomonitoring; and health-risk potential.

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Paclitaxel : Sources, Chemistry, Anticancer Actions, and Current Biotechnology

Provides a comprehensive survey of Paclitaxel and its derivatives chemistry, biosynthesis and anticancer activities. In addition, biotechnological methods, including cell cultures, the use of bioreactors and metabolic engineering strategies to improve Paclitaxel production are also discussed. The book discusses topics such as mechanisms of action against cancer, novel forms of Paclitaxel for an effective cancer treatment, strategies for enhancing its bioavailability, and the application of nanocarriers for its delivery and chemotherapy of cancer.

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