الصفحة 29
الصفحة 29
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Botanical drug products : Recent developments and market trends

Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process.

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Borderless Knowledge : Understanding the “New” Internationalisation of Research and Higher Education in Norway

this book analyses patterns of internationalisation comprising the national and supranational level, the level of higher education institutions and private companies, as well as the level of individual researchers and graduates. As a laboratory for studying internationalisation the book uses the case of Norway, a small knowledge system set in an open society, political system and economy. The case offers exceptionally good data on the developments in its research and higher education system that record changes over time and across the different parts and levels of a national knowledge system.

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Bone augmentation in implant dentistry : A step-by-step guide to predictable alveolar ridge and sinus grafting

Implant dentistry has evolved tremendously over the past three decades and is rapidly progressing as new materials and protocols become available each year. With the number of advancements made in digitally based media and marketing, it is imperative that the clinician is able to separate new trends from evidence-based protocols to make sound and predictable choices for the ultimate benefit of patients. This textbook presents cases from the author's 35-year practice to show the successes and failures of various treatment approaches and protocols. Early chapters discuss the relevant biomaterials and instruments utilized for bone augmentation protocols, including barrier membranes, bone grafting materials, and growth factors. Surgical chapters dedicated to extraction socket management, alveolar ridge augmentation, and sinus grafting follow, each chapter detailing specific indications and patient selection criteria as well as step-by-step surgical procedures, aspects of postoperative treatment, and complications. The final chapter focuses on full-arch reconstruction using fully guided immediate reconstruction protocols. The author's teaching institute is credited with preparing some of the world's best clinicians, and this book will pave the way for countless more.

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Bonding in Microsystem Technology

Bonding in Microsystem Technology starts with descriptions of terminology, kinds of microsystems and market analysis. Followed by the presentation of mechanisms of wet etching, set of process parameters, description of micromachining methods, examples of procedures, process flow-charts and applications of basic micromechanical structures in microsystems are shown. Next, high-temperature, low temperature and room-temperature bonding and their applications in microsystem technology are presented. The following part of the book contains the detailed description of anodic bonding, starting from analysis of properties of glasses suitable for anodic bonding, and discussion of the nature of the process. Next all types of anodic bonding and sealing procedures used in microsystem technology are presented.

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Bond Portfolio Optimization

1 The tools of modern portfolio theory are in general use in the equity markets, either in the form of portfolio optimization software or as an accepted frame- 2 work in which the asset managers think about stock selection. In the ?xed income market on the other hand, these tools seem irrelevant or inapplicable. Bond portfolios are nowadays mainly managed by a comparison of portfolio 3 4 risk measures vis ¶a vis a benchmark. The portfolio manager’s views about the future evolution of the term structure of interest rates translate th- selves directly into a positioning relative to his benchmark, taking the risks of these deviations from the benchmark into account only in a very crude 5 fashion, i.e. without really quantifying them probabilistically. This is quite surprising since sophisticated models for the evolution of interest rates are commonly used for interest rate derivatives pricing and the derivation of ?xed 6 income risk measures.

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Blockchain and crypto currency : Building a high quality marketplace for crypto data

This book contributes to the creation of a cyber ecosystem supported by blockchain technology in which technology and people can coexist in harmony. Blockchains have shown that trusted records, or ledgers, of permanent data can be stored on the Internet in a decentralized manner.

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Biosimilars : Regulatory, clinical, and biopharmaceutical development

Provides a comprehensive overview of the biosimilar regulatory framework, the development process and clinical aspects for development of biosimilars. The development path of a biosimilar is just as unique as a development path of a new drug, tailored by the mechanism of action, the quality of the molecule, published information on the reference product, the current competitive environment, the target market and regulatory guidance, and most importantly, the emerging totality of evidence for the proposed biosimilar during development.

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Biologically Inspired Algorithms for Financial Modelling

Then Part I provides a thorough guide to the various bioinspired methodologies – neural networks, evolutionary computing (particularly genetic algorithms and grammatical evolution), particle swarm and ant colony optimization, and immune systems. Part II brings the reader through the development of market trading systems. Finally, Part III examines real-world case studies where BIA methodologies are employed to construct trading systems in equity and foreign exchange markets, and for the prediction of corporate bond ratings and corporate failures.

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Bioinformatics tools for pharmaceutical drug product development

Presents the latest information on bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies. And include bioinformatics tools for the pharmaceutical sector and the healthcare sector. Bioinformatics brings a new era in research to accelerate drug target and vaccine design development, improving validation approaches as well as facilitating and identifying side effects and predicting drug resistance. As such, this will aid in more successful drug candidates from discovery to clinical trials to the market, and most importantly make it a more cost-effective process overall.

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Biogeochemistry of Trace Elements in Arid Environments

Global warming has worsened the water resource crisis in many arid zones worldwide, from Africa to Asia, affecting millions of people and putting them at risk of hunger. Effective management of arid zone resources, including understanding the risks of toxic trace and heavy elements to humans, coupled with the need to produce more food to feed the world’s growing population, has thus become increasingly important. This very timely book, the only one of its kind on the market, fills the gap of our knowledge of trace elements in these regions. This book begins by introducing the nature and properties of arid zone soil, followed by an updated overview and comprehensive coverage of the major aspects of the trace elements and heavy metals of most concern in the world’s arid and semi-arid soils. These aspects include: - content and distribution - solution chemistry - solid-phase chemistry - selective sequential dissolution techniques - transfer fluxes - bioavailability - pollution and remediation In order to illustrate the themes, a comprehensive and focused case study on transfer fluxes of trace elements in Israeli arid soils is presented. Finally it closes with the global perspectives on anthropogenic interferences in the natural trace elements’ distribution.

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Big little hotel : Small hotels designed by architects

This book showcases small hotels, all located in the United States, designed by architects who use light and materials in interesting and intentional ways. The designs also deliberately connect to their local history, context, or land – in many cases all three. Both the architecture and the operations harmonize with the place, whether that is a bustling city, small town, or natural area. Many are new buildings but some are adaptive reuse projects or renovations of historic properties, extending the connectivity of the place into the future.

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Big Data : A Road Map for Successful Digital Marketing

Explores recent trends in the use of big data to predict consumer behavior, strategies to engage online customers, integration of big data with other data sources, and its applications in social media analytics, mobile marketing, search engine optimization and customer relationship management.

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Berufliche passagen im lebenslauf : berufsbildungs- und transitionsforschung in der Schweiz = Vocational passages in the CV : Vocational training and transition research in Switzerland

During the transition from school to work, important groundwork is laid that prepares the further course of a person's life. In addition, this volume presents new results from diverse transition research from all over Switzerland, which are based on various disciplines such as psychology, sociology, educational sciences or educational economics. For this purpose, theoretical foundations and empirical evidence for the analysis and control of significant passages in the life course are developed.

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Benefits realisation : The change-driven approach to project success

In Benefits Realisation: The Change-Driven Approach to Project Success, renowned benefits realisation expert, speaker, and consultant Rasmus Rytter introduces a new approach to change projects where benefits realisation defines the design of the project and how it’s led. Once the project’s benefits have been defined, the key question for the project to answer is: ‘How might we help our colleagues change their behaviour? Thus, identifying behavioural change as the key driver of benefit realisation.

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Behavioural research for marketing : A practitioner's handbook

Provides market researchers and marketeers with the tools to better understand human behaviour by drawing upon social science theory from different schools of thought, including sociology, psychology and behavioural economics. It has practical examples throughout to help illustrate how to operationalise theory in market research and to underpin the way we understand how people think, behave, decide and make choices.

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Behavioral interventions for prevention and control of sexually transmitted diseases

Before AIDS, the role of behavioral interventions in preventing transmission of sexually transmitted diseases was acknowledged in text books and journals but rarely promoted effectively in public health practice. Informed by a comprehensive knowledge of behavioral theory, intervention methods, and affected populations, the authors of this important book examine the central role of behavioral interventions in combating STDs. The book addresses the complexities and social contexts of human behaviors which spread STDs, the cultural barriers to STD education (ranging from conservative mores to "stay out of my bedroom" libertarianism), and the sociopolitical nuances surrounding treatment.

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Behavioral finance and your portfolio : A navigation guide for building wealth

Designed for investors who are serious about maximizing their gains, in this book you’ll discover how to: ● Take control of your decision-making—even when challenging markets push greed and fear to intolerable levels ● Reflect on how to make investment decisions using data-backed and substantiated information instead of emotion and bias ● Counter deep-seated biases like loss aversion, hindsight and overconfidence with self-awareness and hard facts ● Identify your personal investment psychology profile, which you can use to inform your future financial decision making

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Behavioral competencies of digital professionals : Understanding the role of emotional intelligence

Shedding new light on the human side of big data through the lenses of emotional and social intelligence competencies, this book advances the understanding of the requirements of the different professions that deal with big data. It also illustrates the empirical evidence collected through the application of the competency-based methodology to a sample of data scientists and data analysts, the two most in-demand big data jobs in the labor market.

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Beginning DB2 : From novice to professional

IBM’s DB2 Express Edition is one of the most capable of the free database platforms available in today’s marketplace. In Beginning DB2, author Grant Allen gets you started using DB2 Express Edition for web sites, desktop applications, and more. The author covers the basics of DB2 for developers and database administrators, shows you how to manage data in both XML and relational form, and includes numerous code examples so that you are never in doubt as to how things work.

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Bee products : Chemical and biological properties

Presents an updated discussion on the chemical composition and biological properties of the main bee products, which until now have been presented separately in different editions This book scoops out studies about bee products most used in marketing and in traditional medicine such as honey, royal jelly, propolis, bee pollen and bee venom Discusses chemical composition and biological function of the different bee products on topics such as nutrition, aging and age-related diseases, cancer, neurodegenerative diseases and pathogen infections Bee products are rich in several essential nutrients and non essential nutrients, as sugars, minerals, proteins, free amino acids, vitamins, enzymes and polyphenols, that seem to be closely related to their biological functions. The effects of these products in nutrition, aging and age-related diseases, cancer, neurodegenerative diseases and pathogen infections are discussed.

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